Featured

• A Neuromarker for Drug and Food Craving Distinguishes Drug Users from Non-Users.
• Low subjective social status is associated with daily selection of fewer healthy foods and more high-fat/high sugar foods.
• Randomization, Design and Analysis for Interdependency in Aging Research: No Person or Mouse Is an Island.
• Endosomal Lipid Signaling Reshapes the Endoplasmic Reticulum to Control Mitochondrial Function.

Headline vs Study

• Headline: What Causes Childhood Obesity? New Study Says a Single Gene Could Be Responsible.
• Study: Aberrant Expression of Agouti Signaling Protein (ASIP) as a Cause of Monogenic Severe Childhood Obesity... In 5 of 1,746 Children with Overweight or Obesity.

Contrary or Null Findings

• Urbanization Does Not Endanger Food Security: Evidence from China's Loess Plateau.
• RCT: Early Nutritional Intervention Does Not Prevent Long-Term Adverse Events in Women with Breast Cancer.
• Recapitulation of Anti-Aging Phenotypes by Global, but Not by Muscle-Specific, Deletion of PAPP-A in Mice.
• "We found inconsistent evidence that a child’s BMI affected their depressive and ADHD symptoms, and little evidence that a child’s BMI affected their anxiety symptoms."
• Iron Supplementation Does Not Aggravate Impaired Glucose Tolerance and Sugar Overload-Induced Genotoxicity in Rats.
• Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake.
• RCT: Eight-Hour Time-Restricted Eating Does Not Lower Daily Myofibrillar Protein Synthesis Rates.
• RCT: Acute Pre-Exercise Hydrogen Rich Water Intake Does Not Improve Running Performance at Maximal Aerobic Speed in Trained Track and Field Runners.
• RCTs: Imagined Eating & Satiety - "Priming appeared to be specific to the taste of the exposed stimulus, and satiation, contrary to prior literature, appeared to be more general. Neither colour nor flavour variety reliably moderated any of the responses."

Basic

• Review: Novel Importance of MiR-143 in Obesity Regulation.
• Angiotensin(1–7) Attenuates Visceral Adipose Tissue Expansion and Lipogenesis by Suppression of Endoplasmic Reticulum Stress Via Mas Receptor.
• Brevibacillus laterosporus BL1, a Promising Probiotic, Prevents Obesity and Modulates Gut Microbiota in Mice Fed a High-Fat Diet.
• Empagliflozin Protects Mice Against Diet-Induced Obesity, Insulin Resistance, and Hepatic Steatosis.
• L-Arginine Supplementation Regulates Energy-Substrate Metabolism in Skeletal Muscle and Adipose Tissue of Diet-Induced Obese Rats.

Scientific Rigor & Scholarly Dialogue

• Big Claims, Vexing Flaws of an Intermittent Fasting Study.
• Article: Coffee and Green Tea Consumption and Cardiovascular Disease Mortality Among People with and Without Hypertension.
• Comments: Expert Reaction to Study Looking at Coffee and Green Tea Consumption and Heart Deaths in People with Severe High Blood Pressure.

Clinical

• RCT: Comparison of an Online Versus Conventional Multidisciplinary Collaborative Weight Loss Programme in Type 2 Diabetes Mellitus.
• Review: Intermuscular Adipose Tissue in Metabolic Disease.
• Detailed Versus Simplified Dietary Self-Monitoring in a Digital Weight Loss Intervention Among Racial and Ethnic Minority Adults.
• RCT: Effects of a Web-Based Weight Loss Program on the Healthy Eating Index-NVS in Adults with Overweight or Obesity and the Association with Dietary, Anthropometric and Cardiometabolic Variables.
• RCT: Body Fat Reduction Effect of Bifidobacterium Breve B-3.

Children and Adolescents

• Trends in U.S. Adolescent Physical Activity and Obesity: A 20-Year Age-Period-Cohort Analysis.
• Meta-Analysis: Effects of Nutritional Intervention Strategies in the Primary Prevention of Overweight and Obesity in School Settings.
• Obesity, Overweight and Hyperglycemia Among Primary School Children in a Low-Middle Income Country with a Multiethnic Population.
• Fat Content in Infant Mesenchymal Stem Cells Prospectively Associates with Childhood Adiposity and Fasting Glucose.

Surgery

• Gut Adaptation After Gastric Bypass in Humans Reveals Metabolically Significant Shift in Fuel Metabolism.
• Systematic Review: The Efficacy of GLP-1RAs for the Management of Postprandial Hypoglycemia Following Bariatric Surgery.
• Protein Supplementation with Short Peptides Prevents Early Muscle Mass Loss After Roux-En-Y-Gastric Bypass.

Drugs

• Meta-Analysis: Reducing Craving and Consumption in Individuals with Drug Addiction, Obesity or Overeating Through Neuromodulation Intervention.
• Review: Drug Dosing in Hospitalized Patients with Obesity and COVID-19.
• Effectiveness and Persistence of Anti-Obesity Medications (Liraglutide 3 Mg, Lorcaserin, and Orlistat) in a Real-World Primary Care Setting.
• Effects of Jowiseungki-Tang on High Fat Diet-Induced Obesity in Mice and Functional Analysis on Network Pharmacology and Metabolomics Analysis.

Food & Diet

• Meta-Analysis: Combined Effects of Aspartame and Acesulfame-K Blends on Appetite.
• Perspective: Multi-Sectoral Strategies Needed to Establish Healthy Portion Size Norms That Disincentivize Hyperpalatable, Energy-Dense Foods and Sugary Beverages in Food Environments Linked to Obesity and Diet-Related Chronic Diseases in the United States.
• Multi-Omics Gut Microbiome Signatures in Women with Obesity: Role of Diet and Uncontrolled Eating Behavior.
• Effect of D-β-Hydroxybutyrate-(R)-1,3 Butanediol on Appetite Regulation in People with Prediabetes.

Caloric and Dietary Restriction

• RCT: Effect of an Intermittent Calorie-Restricted Diet on Type 2 Diabetes Remission.
• Effects of Dietary Methionine Restriction on Age-Related Changes in Perivascular and Beiging Adipose Tissues in the Mouse.
• Review: Energy Intake at the Intersection of the Clock and Ageing.

Exercise & Physical Activity

• Association of Longitudinal Activity Measures and Diabetes Risk: An Analysis from the National Institutes of Health All of Us Research Program.
• Review: Myokine, a Key Cytokine for Physical Exercise to Alleviate Sarcopenic Obesity.

Economics & Sociology

• Preprint: Associations of Socioeconomic Status and Obesity with Hypertension in Tibetan Adults in a Chinese Plateau Area.
• G7 Food Security Working Group: Financial Report on Food Security and Nutrition 2020. (pdf)
• Associations of Neighborhood Opportunity and Social Vulnerability with Trajectories of Childhood BMI and Obesity Among US Children.

Epidemiology

• Weight Change Across Adulthood and Accelerated Biological Aging in Middle-Aged and Older Adults.
• Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program.

Psychology & Neuroscience

• Imaginal Retraining Reduces Craving for High-Calorie Food.
• The Concept of “Metabolic Jet Lag” in the Pathophysiology of Bipolar Disorder: Implications for Research and Clinical Care.

Equity and Disparities

• Socioeconomic Disparities in Diabetes Prevalence and Management Among the Adult Population in Bangladesh.
• Neighborhood Disadvantage Is Associated with Decreased Ovarian Reserve in Women with Overweight and Obesity.
• Trends in School-Neighbourhood Inequalities and Youth Obesity: Repeated Cross-Sectional Analyses of the Public Schools in the State of California.

Stigma

• Weight Stigma Among Adolescents in Three Low- and Middle-Income Countries.
• Intuitive Eating Buffers the Link between Internalized Weight Stigma and BMI in Stressed Adults.

Policy Related

• A Scientific Transition to Support the 21st Century Dietary Transition.
• Person-First Treatment Strategies: Weight Bias and Impact on Mental Health of People Living with Obesity.
• Series of Rapid Reviews: Breakfast Consumption by School-Aged Children and Adolescents and School Performance, Weight-Related Outcomes, and Health & U.S. School Breakfast Program Best Practices, Including Models of Student Costs and Breakfast Delivery.
• A Novel Approach to Characterize State-Level Food Environment and Predict Obesity Rate Using Social Media Data: Correlational Study.

Intergenerational Effects

• Egg Introduction During Infancy Is Associated with Lower Fat Mass Index in Females at Early Adolescence.
• RCT: Maternal Well-Being and Stage of Behaviour Change During Pregnancy.
• Maternal BMI in the Preconception Period, and Association with Child zBMI Growth Rates.
• Epigenetic Age Acceleration in Mothers and Offspring 4–10 Years After a Pregnancy Complicated by Gestational Diabetes and Obesity.

Ecology, Evolution, & Energetics

• Review: Finding Balance: Understanding the Energetics of Time-Restricted Feeding in Mice.
• Chronic Intermittent Hypoxia During Sleep Causes Browning of Interscapular Adipose Tissue Accompanied by Local Insulin Resistance in Mice.
• Preprint: Age but Not Menopausal Status Is Linked to Lower Resting Energy Expenditure.

Methods

• A Conductive Hydrogel Microneedle-Based Assay Integrating PEDOT:PSS and Ag-Pt Nanoparticles for Real-Time, Enzyme-Less, and Electrochemical Sensing of Glucose.
• Machine Learning in Nutrition Research.
• Letter: The A, B, C, D's of Dietary Trials.
• Reply to H Staudacher et al.

Commentary

• The Marketing of Plant-Based Protein - the Beyond Meat Case: Making Food Alternatives Appealing to Multiple Groups of Consumers.
• Sugar May Become Healthier Through Wyss, Kraft Heinz Collaboration.
• Starvation Triggers Metabolic Rewiring Crucial for Cellular Survival.
• Tiny Patch Could Give Diabetics Painless Glucose Monitoring.
• A Metabolic Gift for Gaining Weight and Hibernating.
• Common Food Dye Can Trigger Inflammatory Bowel Diseases, Say Researchers.
• Blood-Based Metabolic Signature Outperforms Standard Method for Predicting Diet, Disease Risk: The Study Found That Machine Learning Techniques Improved Diet Prediction by 10-20%.
• Obesity Researchers Discover New Gene Mutation in Children.

General

• Collecting: A Demonic Passion. (pdf)
• WEBINAR | Considerations in the Study of Sex as a Biological Variable in Aging Research February 2, 2023 from 4-5pm ET.
• The Equality Paradox: Gender Equality Intensifies Male Advantages in Adolescent Subjective Well-Being.
• Towards a New Paradigm for ‘Journal Quality’ Criteria: A Scoping Review.
• Neurons Responsible for Maintaining Body Temperature: Study.
• The Musicality of Birds: From Charles Darwin to Hermeto Pascoal.
• Twin Research for Everyone. (pdf)
• Improving the Rigor of Mechanistic Behavioral Science: The Introduction of the Checklist for Investigating Mechanisms in Behavior-Change Research (CLIMBR).
• NIH Plans Grant-Review Overhaul to Reduce Bias.
• Glassfrogs Conceal Blood in Their Liver to Maintain Transparency.

Announcements

• IU Bloomington School of Public Health Seeks Chair of the Department of Environmental and Occupational Health.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Indiana University School of Public Health-Bloomington Is Recruiting for Tenure-Track Faculty in Every Department!