Featured

• The Energy Requirements and Metabolic Benefits of Wilderness Hunting in Alaska.
• Irisin Mediates Effects on Bone and Fat Via αV Integrin Receptors.
• Quantifying the Imprecision of Energy Intake of Humans to Compensate for Imposed Energetic Errors: A Challenge to the Physiological Control of Human Food Intake.
• Compensation in Response to Energy Deficits Induced By Exercise or Diet.

Headline vs Study

• Headline: Fighting Obesity—Could It Be as Plain as Dirt?
• Study: Spray Dried Smectite Clay Particles as a Novel Treatment Against Obesity... In Rats.

Contrary or Null Findings

• RCT: "School feeding had no effect on HAZ and BAZ [height-for-age and BMI-for-age scores] in children aged 5-15 years."
• RCT: No Meaningfully Differential Effects of Different Effects of BodyPump and Traditional Heavy Load Resistance Training.
• RCT: "Videoconference and community‐based delivery were as effective [or as ineffective] as an FQHC‐based weight loss program."
• "Contrary to hypotheses, however, participants reported moderately positive attitudes toward treating the client regardless of BMI."
• "There was no difference in the occurrence of incident metabolic comorbidities between lean NAFLD and non-lean NAFLD."
• "We found no association between early life BMI and subsequent dementia..."
• "we tested the hypothesis that calorically matched interval (INT) training would improve both fasted and post-prandial arterial stiffness more than continuous (CONT) exercise in adults with prediabetes" and found no statistically significant support.
• "We found no evidence for a persistent effect of prenatal exposure to traffic pollution on BMI trajectory from birth through mid-childhood in a population exposed to modest levels of air pollution."
• "...fast food contained 33% less energy than full service meals."

Basic

• Doubled Lifespan and Patient‐like Pathologies in Progeria Mice Fed High‐fat Diet.
• CRISPR-mediated Activation of a Promoter or Enhancer Rescues Obesity Caused By Haploinsufficiency.
• Genetic Nicotinamide N-Methyltransferase (Nnmt) Deficiency in Male Mice Improves Insulin Sensitivity in Diet-Induced Obesity but Does Not Affect Glucose Tolerance.
• Loss of μ-Crystallin Causes PPARγ Activation and Obesity in High-Fat Diet-Fed Mice.
• Sex Differences in Inflammatory Responses to Adipose Tissue Lipolysis in Diet-Induced Obesity.

Scientific Rigor & Scholarly Dialogue

• Establishing Validity and Cross-Context Equivalence of Measures and Indicators.
• Quantifying the Imprecision of Energy Intake of Humans to Compensate for Imposed Energetic Errors: A Challenge to the Physiological Control of Human Food Intake.
• The Case of GWAS of Obesity: Does Body Weight Control Play By the Rules?
• Letter: GWAS for BMI. A Treasure Trove of Fundamental Insights Into the Genetic Basis of Obesity.
• Thanks for Opening an Overdue Discussion on GWAS of BMI: A Reply to Prof. Speakman et al.

Clinical

• RCT: The ICook 4-H Study: Report on Physical Activity and Sedentary Time in Youth Participating in a Multicomponent Program Promoting Family Cooking, Eating, and Playing Together.
• Bariatric Surgery, Lifestyle Interventions and Orlistat for Severe Obesity: The REBALANCE Mixed-methods Systematic Review and Economic Evaluation.
• Exercise and Diet: Different Tools for Different Jobs. (pdf)
• Is Waist Circumference More Strongly Associated with Metabolic Risk Factors than Waist-to-height Ratio in Asians?
• RCT: Effectiveness of a Brief Behavioural Intervention to Prevent Weight Gain Over the Christmas Holiday Period.

Children and Adolescents

• 2‐hr Vs. 1‐hr Glucose Tolerance Testing: Predicting Prediabetes in Adolescent Girls with Obesity.
• RCT: Implementing School-Based Policies to Prevent Obesity.

Surgery

• Change in Brain Volume and Cortical Thickness After Behavioral and Surgical Weight Loss Intervention.
• Lack of Standard Definitions of Primary and Secondary (Non)responders After Primary Gastric Bypass and Gastric Sleeve: A Systematic Review.

Drugs

• RCT: Pegbelfermin (BMS-986036), PEGylated FGF21, in Patients with Obesity and Type 2 Diabetes.
• Liraglutide Induces Beige Fat Development and Promotes Mitochondrial Function in Diet Induced Obesity Mice Partially Through AMPK-SIRT-1-PGC1-α Cell Signaling Pathway.

Food & Diet

• RCT: Effect of Dried Fruit on Postprandial Glycemia.
• Blueberry Containing Diets Protect From Bone Loss Induced By Sex Steroid Deficiency Differently Depending on Sex and By Mechanisms Independent of Canonical Sex Steroid Receptor Signaling.
• RCT: Anti-obesity and Anti-hyperlipidemic Activity of Processed Honey.
• RCT: A 12-wk Whole-grain Wheat Intervention Protects Against Hepatic Fat in Overweight Subjects.
• Strategies to Improve Bioavailability of Omega-3 Fatty Acids From Ethyl Ester Concentrates.

Caloric Restriction

• Dietary Methionine Restriction Reduces Hepatic Steatosis and Oxidative Stress in High-fat-fed Mice By Promoting H2S Production.
• Caloric Restriction Rescues Yeast Cells From Alpha-synuclein Toxicity Through Autophagic Control of Proteostasis.
• Intermittent Fasting Exerts Beneficial Metabolic Effects on Blood Pressure and Cardiac Structure By Modulating Local Renin-angiotensin System in the Heart of Mice Fed High-fat or High-fructose Diets.
• Impact of Calorie Restriction on Glycemic Control in Overweight Patients with Type 2 Diabetes Mellitus.

Exercise & Physical Activity

• The Impact of Physical Activity to the Child’s Quality of Life: A Synthetic Review.
• Decompression Sickness, Fatness and Active Hydrophobic Spots.
• Physical Activity Less than the Recommended Amount May Prevent the Onset of Major Biological Risk Factors for Cardiovascular Disease: A Cohort Study of 198,919 Adults.
• Benefits of Resistance Training on Body Composition and Glucose Clearance are Inhibited By Long-term Low Carbohydrate Diet in Rats.
• Determinants of Changes in Physical Activity From Pre-diagnosis to Post-diagnosis in a Cohort of Prostate Cancer Survivors.

Economics & Sociology

• Socioeconomic Differences in BMI in Spain: An Intersectional Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy.
• Soda, Salad, and Socioeconomic Status: Findings From the Seattle Obesity Study (SOS).
• Socioeconomic Status in Relation to Childhood General and Central Obesity in Primary School Children in the City of Farokh Shahr in 2009.

Epidemiology

• Associations of Body Mass and Fat Indexes with Cardiometabolic Traits.
• Exploring the Role of Family Functioning in the Association Between Frequency of Family Dinners and Dietary Intake Among Adolescents and Young Adults.
• Body Composition and Mortality in the General Population: A Review of Epidemiologic Studies.
• Inverse Association Between Metabolic Syndrome and Altitude: A Cross-Sectional Study in an Adult Population of Ecuador.
• Severe Housing-cost Burden and Obesity Among Preschool-aged Low-income Children in Los Angeles County.

Psychology & Neuroscience

• Weight Self-stigma and Weight Loss During Behavioral Weight Loss Intervention.
• A Healthy Lifestyle Decreases the Risk of Obesity Among Children at High Polygenic Risk.
• Race and Income Moderate the Association Between Depressive Symptoms and Obesity.
• Healthcare Providers’ Advice on Lifestyle Modification in the US Population.
• Implications of Agency in Studies of Self-regulation and Obesity.

Equity and Disparities

• Ethnic Differences in Eating Disorder Prevalence, Risk Factors, and Predictive Effects of Risk Factors Among Young Women.
• Developing Key Performance Indicators for Guaranteeing Right to Health and Access to Medical Service for Persons with Disabilities in Korea: Using a Modified Delphi.
• Protective Factors Associated with Fewer Generalized Anxiety Disorder Symptoms Among Women Exposed to Intimate Partner Violence.

Stigma

• Understanding the Psychosocial Impact of Weight Loss Following Bariatric Surgery: A Qualitative Study.
• Healthy Life Centre Participants’ Perceptions of Living with Overweight or Obesity and Seeking Help for a Perceived “wrong” Lifestyle.
• Weight Stigma and Its Impact on Pediatric Care.
• Explicit and Implicit Measures of Weight Stigma in Young Children.
• Assessment of Public Attitudes Toward Weight Loss Surgery in the United States.

Policy Related

• What Factors Influence Ultra-processed Food Purchase and Consumption in Households with Children? A Comparison Between Participants and Non-participants of the Supplemental Nutrition Assistance Program (SNAP).
• Addressing Food Insecurity in Vulnerable Populations.
• What Young Australians Think About a Tax on Sugar-sweetened Beverages.
• Structural Responses to the Obesity and Non‐communicable Diseases Epidemic: Update on the Chilean Law of Food Labelling and Advertising.
• Environmental Impact on Health Across Generations: Policy Meets Biology. A Review of Animal and Human Models.

Intergenerational Effects

• Genetic Insights Into Fetal Growth and Measures of Glycaemic Regulation and Adiposity in Adulthood: A Family-based Study.
• Dietary Fish Oil Supplementation During Early Pregnancy in Rats on a Cafeteria-diet Prevents Fatty Liver in Adult Male Offspring.
• The Influence of Maternal BMI and Physical Activity on Select Cardiovascular Risk Factors of Preadolescent Hispanic Children.
• Paternal Grandfather’s Access to Food Predicts All-cause and Cancer Mortality in Grandsons.
• Early Post-conception Maternal Cortisol, Children’s HPAA Activity and DNA Methylation Profiles.

Ecology, Evolution, & Energetics

• Containing Obesity From a Human Evolutionary Perspective.
• Sperm Competition and the Evolution of Male Reproductive Anatomy in Rodents.

Methods

• The Reachable 3-D Workspace Volume is a Measure of Payload and Body-mass-index: A Quasi-static Kinetic Assessment.
• Imputing Missing Values for Improved Statistical Inference Applied to Intrauterine Growth Restriction Problem.
• Challenges of Non–Intention-to-Treat Analyses.

Mathematical and Quantitative

• Mathematical Model of Hemodynamic Mechanisms and Consequences of Glomerular Hypertension in Diabetic Mice.
• Multiscale Mathematical Modeling Vs. The Generalized Transfer Function Approach for Aortic Pressure Estimation: A Comparison with Invasive Data.
• Random-Effects Meta-analysis: Summarizing Evidence with Caveats.

Commentary

• Just Thinking You Have Poor Endurance Genes Changes Your Body.
• Population Declines in Grip Strength.
• The Misleading Fast Food Boogeyman.

General

• Size‐dependent Mating Pattern in a Nuptial Gift‐giving Insect.
• Contrary to Common Belief, RCTs Inevitably Produce Biased Results.
• Key Opinion Leaders’ Guide to Spinning a Disappointing Clinical Trial Result.
• Genetic Mutation Drives Tumor Regression in Tasmanian Devils.
• Frog Sex in the City.
• No Place for ‘Trial By Media’ in Bullying Allegations.

Video & Audio

• TedTalk: 3 Kinds of Bias that Shape Views on Science Matters.
• PodCast: Siddhartha Mukherjee, M.D., Ph.D.: New Frontiers in Cancer Therapy, Medicine, and the Writing Process.
• Video: Regression to the Mean in Nutrition and Obesity Research.
• Recordings From NUTRITION 2018 are Now Available.

Announcements

• NORC of UAB Seeks Postdoctoral Fellows in Obesity Research.
• UAB Seeks Postdoctoral Fellows for Its AHA Strategically Focused Research Center– Obesity Network: Intergenerational Transmission of Obesity.
• IU School of Public Health Bloomington Initiates Major Wave of Faculty Recruitment – Tenure-track Positions Available in Every Department and Two Department Chairs Open: See Multiple Listings Posted Here.