Featured

• Meta-Analysis: "In conclusion, SGLT2 inhibitors reduce all-cause mortality in randomized-controlled trials."
• Life’s Energy and Information: Contrasting Evolution of Volume- Versus Surface-Specific Rates of Energy Consumption.
• Association between Achieving Inpatient Glycemic Control and Clinical Outcomes in Hospitalized Patients with COVID-19: A Multicenter, Retrospective Hospital-Based Analysis.

Headline vs Study

• Headline: Increasing Water Intake May Help Prevent, Treat Metabolic Syndrome.
• Press-release: Water May Be an Effective Treatment for Metabolic Syndrome.
• Study: Vasopressin Mediates Fructose-induced Metabolic Syndrome by Activating the V1b Receptor... In Mice and Immortal Cells.

Contrary or Null Findings

• RCT: "Overall, multiple food-specific or generic ICT sessions over the course of a four-week period do not affect overall weight loss, caloric intake, or N2 ERP amplitude."
• RCT: "While this trial was a pilot study and not powered to detect a difference between groups, there was no suggestion of any clinically important impact of this financial incentive on postoperative ambulation."
• RCT: No significant effect in "a 3-month ...feasibility trial comparing app-based diet tracking (active comparator) to app-based diet tracking plus feedback on DASH adherence via text message (intervention)."
• "The present study was unable to show any clear associations between ICFI [Infant and Child Feeding Index] and nutritional status..."
• "Contrary to expectations, DIP [glutamine and alanine supplementation, as dipeptide] administration increased central fatigue parameters, such as plasma concentration of free fatty acids (FFA), hypothalamic content of serotonin and serotonin/dopamine ratio" in rats.
• "Contrary to predictions, the monkeys spent equal proportions of time feeding...in forest edge and interior."
• RCT: No Differential Effect of Intermittent vs Continuous Energy Restriction Result in Similar Weight Loss, Weight Loss Maintenance, and Body Composition Changes.
• RCT: "Consumption of a Beverage Containing Aspartame and Acesulfame K for Two Weeks Does Not Adversely Influence Glucose Metabolism in Adult Males and Females."

Basic

• Resistin Is Co-Secreted with Adiponectin in White Mouse Adipocytes.
• Chronic Circadian Shift Leads to Adipose Tissue Inflammation and Fibrosis in Mice.
• Oxidative Stress and Neuroinflammation in a Rat Model of Co-Morbid Obesity and Psychogenic Stress.
• HIF1α Activation in Dendritic Cells Under Sterile Conditions Promotes an Anti-Inflammatory Phenotype Through Accumulation of Intracellular Lipids.
• The Effects of Ovariectomy on the Behavioral and Physiological Responses to Constant Light in C57BL6/J Mice.
• Appetite Regulating Hormones are Reduced After Oral Sucrose vs Glucose: Influence of Obesity, Insulin Resistance and Sex.

Scientific Rigor & Scholarly Dialogue

• PubPeer Comment On: Could Ketogenic Diet “starve” Cancer? Emerging Evidence.
• PubPeer Comments on: Exercise for Weight Loss.
• Retraction: Is Interval Training the Magic Bullet for Fat Loss? A Systematic Review and Meta-analysis Comparing Moderate-intensity Continuous Training with High-intensity Interval Training (HIIT).

Clinical

• Driver Versus Navigator Causation in Biology: The Case of Insulin and Fasting Glucose.
• The Impact of Obesity in End of Life Care in Patients with End Stage Liver Disease: An Observational Study.
• Body Weight Management in Breast Cancer Survivors with Overweight and Obesity.
• RCT: Combined Effects of Continuous Exercise and Intermittent Active Interruptions to Prolonged Sitting on Postprandial Glucose, Insulin, and Triglycerides in Adults with Obesity.
• RCT: Intermittent and Continuous Energy Restriction Result in Similar Weight Loss, Weight Loss Maintenance, and Body Composition Changes.

Children and Adolescents

• Associations of Maternal Fructose and Sugar-sweetened Beverage and Juice Intake During Lactation with Infant Neurodevelopmental Outcomes at 24 Months.
• The Impact of Obesity on Left Ventricular Hypertrophy and Diastolic Function in Caucasian Children.
• Physical Activity and Screen Time of Children and Adolescents Before and During the COVID-19 Lockdown in Germany: A Natural Experiment.
• Childhood Exposure to Parental Smoking and Lifecourse Overweight and Central Obesity.

Surgery

• RCT: Effect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss and Quality of Life at 7 Years in Patients with Morbid Obesity.
• Partial Restoration of Normal Intestinal Microbiota in Women with Morbid Obesity Six Months After Bariatric Surgery.
• Granzyme B Expression in Visceral Adipose Tissue Associates with Local Inflammation and Glyco-Metabolic Alterations in Obesity.

Drugs

• Anti-Obesity Natural Products Tested in Juvenile Zebrafish Obesogenic Tests and Mouse 3T3-L1 Adipogenesis Assays.
• Pharmacotherapy in Pediatric Obesity: Current Evidence and Landscape.
• Obesity Treatment in Patients Both with and Without Diabetes: Current Options and Perspectives.

Food & Diet

• RCT: Effects of Fasting-Mimicking Diet and Specific Meal Replacement Foods on Blood Glucose Control in Patients with Type 2 Diabetes.
• Meta-analysis: Calcium Supplements and Dairy Products for Changes in Body Weight and Obesity Indices.
• The Importance of 24-h Metabolism in Obesity-related Metabolic Disorders: Opportunities for Timed Interventions.
• Review: A Rational Review on the Effects of Sweeteners and Sweetness Enhancers on Appetite, Food Reward and Metabolic/adiposity Outcomes in Adults.

Caloric and Dietary Restriction

• Middle Age as a Turning Point in Mouse Cerebral Cortex Energy and Redox Metabolism: Modulation by Every-other-day Fasting.
• Enhanced Weight and Fat Loss from Long-term Intermittent Fasting in Obesity-prone, Low-fitness Rats.
• RCT: PROFAST: Assessing the Effects of Intermittent Fasting and Lacticaseibacillus Rhamnosus Probiotic Among People with Prediabetes.

Exercise & Physical Activity

• Meta-Analysis: Resistance Training Is Associated with Significantly Improved Hip-related Quality of Life, Symptoms, and Sports and Recreation, and Decreased Pain Scores in Post-hip Replacement Patients.
• Effect of EHealth to Increase Physical Activity in Healthy Adults over 55 Years.
• The Influence of Physical Activity on the Bioactive Lipids Metabolism in Obesity-Induced Muscle Insulin Resistance.
• Carbohydrate Requirements for Prolonged, Fasted Exercise with and Without Basal Rate Reductions in Adults with Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion.

Economics & Sociology

• Transitions Among BMI States: A Test of Competing Hypotheses.
• Objectively Measured Waist Circumference Is Most Strongly Associated in Father–boy and Mother–girl Dyads in a Large Nationally Representative Sample of New Zealanders.

Epidemiology

• Cardiometabolic Morbidity and Mortality with Smoking Cessation, Review of Recommendations for People with Diabetes and Obesity.
• Association between High Birth Weight and Later Central Obesity in 9-Year-Old Schoolchildren.
• BMI Trajectories Among People with Obesity and Association with Mortality: Evidence from a Large Israeli Database.
• Meta-Analysis: Association between Obesity and Depression Among Community-Dwelling Older Adults.
• Prevalence of Overweight, Obesity, and Severe Obesity Among Children and Adolescents Aged 2–19 Years: United States, 1963–1965 Through 2017–2018.
• Brief Communication: Impact of COVID-19 Lockdown on Activity Patterns and Weight Status Among Youths in China: The COVID-19 Impact on Lifestyle Change Survey (COINLICS).
• Brief Communication: The Association between BMI Class and Coronavirus Disease 2019 Outcomes.

Psychology & Neuroscience

• Barriers to Adherence to a Weight Loss Diet in Women.
• Bi-Directional Associations between Real-Time Affect and Physical Activity in Weight-Discordant Siblings.
• Food Reward Sensitivity, Impulsivity, and Weight Change During and After a 3-month Weight Loss Program.
• RCT: Exploring Attitudes, Subjective Norms and Perceived Behavioural Control in a Genetic-Based and a Population-Based Weight Management Intervention.
• Perceived Willpower Self-efficacy Fluctuates Dynamically with Affect and Distress Intolerance.
• Direct and Indirect Effects of Poor Sleep Quality on BMI and Waist Circumference in a Female Population-based Study in Southern Brazil.

Equity and Disparities

• A Culturally and Gender Responsive Stress and Chronic Disease Prevention Intervention for Low/no-income African American Men: The MOCHA Moving Forward RCT Protocol. (pdf)
• Less Obesity but Higher Inequalities in Portuguese Children: Trends of Childhood Obesity between 2002-2016.

Stigma

• Discrimination in the Health Care System Among Higher-weight Adults: Evidence from a Canadian National Cross-sectional Survey.

Policy Related

• On Shape and Being Shaped - Rethinking the Urban Built Environment as a Catalyst of Childhood Inactivity and Obesity.
• Energy Imbalance: Obesity, Associated Comorbidities, Prevention, Management and Public Health Implications.

Intergenerational Effects

• Observations of Maternal Feeding Practices and Styles and Young Children's Obesity Risk: A Longitudinal Study of Hispanic Mothers with Low Incomes.
• The Role of Vitamin A and Its Pro-vitamin Carotenoids in Fetal and Neonatal Programming: Gaps in Knowledge and Metabolic Pathways.

Ecology, Evolution, & Energetics

• Prey Preferences of Modern Human Hunter-gatherers.
• Breaking Free from Thermodynamic Constraints: Thermal Acclimation and Metabolic Compensation in a Freshwater Zooplankton Species.

Methods

• Regression to the Mean Contributes to the Apparent Improvement in Glycemia 3.8 Years After Screening: The ELSA-Brasil Study.
• Comparison of Anthropometric Measures in US Military Personnel in the Classification of Overweight and Obesity.
• Dietary Metabolite Profiling Brings New Insight into the Relationship between Nutrition and Metabolic Risk: An IMI DIRECT Study.

Mathematical and Quantitative

• A Systematic Comprehensive Longitudinal Evaluation of Dietary Factors Associated with Acute Myocardial Infarction and Fatal Coronary Heart Disease.
• Relative Fat Mass Index Can Be Solution for Obesity Paradox in Coronary Artery Disease Severity Prediction Calculated by SYNTAX Score.

Commentary

• Is American Dietetics a White-Bread World? These Dietitians Think So.
• Exercise for Weight Loss: The Lie That Won’t Die.
• Race, Ethnicity, and Racism in the Nutrition Literature: An Update for 2020.
• Preconception Dilemma for Women with Obesity: Is It Worth Waiting to Lose Weight?
• A Blind Spot for Diversity in Nutrition?
• Psychological Aspects of Obesity.
• Dogs and Owners May Share Resemblance in Diabetes Risk.
• Study Finds No Evidence That Vegan Diet Benefits Specific Blood Type.
• Moderna Vaccine Works Well, Even with Severe Obesity.

General

• Race, Ethnicity, and Racism in the Nutrition Literature: An Update for 2020.
• The Effect of Offspring Sex on Parents’ Migration Probabilities and Outcomes—A Natural Experiment.
• RCT: The Effects of Four Doses of Vitamin D Supplements on Falls in Older Adults: A Response-Adaptive RCT.
• World Leaders are Waking Up to the Ocean’s Role in a Healthy Planet.
• Childbirth and the Women’s Aging Process.
• IEEE’s Refusal to Issue Corrections.
• Video: Smart Spoon for People with Parkinson's Disease.
• Statistical Discrimination and the Rationalization of Stereotypes.
• Fruit Flies are Essential to Science. So are the Workers Who Keep Them Alive [at Indiana University's Bloomington Drosophila Stock Center].

Announcements

• Indiana University School of Public Health-Bloomington’s Department of Kinesiology Ranked 11th in the Nation.
• Award Opportunity: New Award from American Society for Nutrition Foundation for Scientific Achievements in Obesity Research.
• Award Opporunity: Expanded Call for Nominations for ASN Junior and Mid-Career Scientific Achievement Awards.
• The Department of Environmental and Occupational Health at Indiana University School of Public Health-Bloomington (SPH-B) Invites Applications to Join the Faculty of the Department of Environmental and Occupational Health.
• IU Bloomington School of Public Health to Offer New Advanced Degrees in Biostatistics in Next Academic Year.