Featured

• Do Lower-Carbohydrate Diets Increase Total Energy Expenditure? An Updated and Reanalyzed Meta-Analysis of 29 Controlled-Feeding Studies.
• Similar Foraging Energetics of Two Sympatric Albatrosses Despite Contrasting Life Histories and Wind-mediated Foraging Strategies.

Headline vs Study

• Headline: Obesity Drives Breast Cancer Risk for Black Women.
• Press-release: Study Finds Obesity Contributes to 40% Mortality Gap between Black and White Women with Early Breast Cancer.
• Study: Associations Among Obesity, Comorbidities, and Treatment Selection in Black and White Women with Early Breast Cancer.

Contrary or Null Findings

• RCT: "This study showed that physical exercise interventions did not enhance executive functioning in children."
• "There were only minimal associations of DNA methylation with childhood and adolescent BMI. …These findings may be compatible with the hypothesis that DNA methylation differences are mostly a consequence rather than a cause of obesity."
• Attenuated Early Pregnancy Weight Gain by Prenatal Lifestyle Interventions Does Not Prevent Gestational Diabetes in the LIFE-Moms Consortium.
• "The failure to find a relationship between parental feeding synchrony and nest survival seems exceptional because it is contrary to findings of previous studies."
• RCT: Few Structural Brain Changes Associated with Moderate-Intensity Interval Training and Low-Intensity Continuous Training in Older Adults.
• RCT: "The macronutrient composition of an isoenergetic WM diet did not affect fasting appetite-related hormone concentrations."
• RCT: Habitual Caffeine Consumption Does Not Affect the Ergogenicity of Coffee Ingestion During a 5 Km Cycling Time Trial.
• RCT: "A hypocaloric high-protein diet along with fennel supplementation could not provide additional improvements in anthropometric and androgen indices among PCOS women."
• RCT: No Consistent Statistically Significant Effect at 5-Year Follow-Up of a Telephone Intervention to Increase Fruit and Vegetable Consumption in Preschoolers: The ‘Healthy Habits’ Trial.

Basic

• Whole Red Raspberry (Rubus Idaeus)-Enriched Diet Is Hepatoprotective in the Obese Zucker Rat, a Model of the Metabolic Syndrome.
• Inhibition of Mitochondrial Fission and INOS in the Dorsal Vagal Complex Protects from Overeating and Weight Gain.
• Gamma-Oryzanol as a Possible PPAR-γ Agonist in Adipose Tissue May Represent a Coadjutant Therapeutic to Prevent Cytokine Storm in COVID-19 Patients with Obesity.
• Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity.
• Sex Differences in Macrophage Responses to Obesity-Mediated Changes Determine Migratory and Inflammatory Traits.
• How Targeting Fat Cells’ Estrogen Receptors Could Fight Obesity.

Scientific Rigor & Scholarly Dialogue

• Retraction Note: Dietary Patterns and Their Associations with Socio-demographic and Lifestyle Factors in Tasmanian Older Adults: A Longitudinal Cohort Study.
• Republished: Longitudinal Associations of Dietary Patterns with Sociodemographic and Lifestyle Factors in Older Adults: The TASOAC Study.
• Editorial: "...we commend the authors’ intellectual honesty..."
• Letter: Covid-19 and Vit-D: Disease Mortality Negatively Correlates with Sunlight Exposure.
• Reply: Response to Naudet et al.

Clinical

• RCT: Post-weight Loss Changes in Fasting Appetite- and Energy Balance-related Hormone Concentrations and the Effect of the Macronutrient Content of a Weight Maintenance Diet.
• Meta-analysis: Effects of Capsicum Annuum Supplementation on the Components of Metabolic Syndrome.
• Meta-analysis: The Effect of the Magnitude of Weight Loss on Non-alcoholic Fatty Liver Disease.
• Feasibility of a Digital Health Intervention to Improve Diet Quality Among Women with High Blood Pressure.

Children and Adolescents

• Obesogenic Environment and Childhood Obesity.
• Systematic Review: Metabolic Syndrome in Children and Adolescents: Is There a Universally Accepted Definition? Does It Matter?

Surgery

• Bariatric Surgery for Patients with Type 2 Diabetes Mellitus Requiring Insulin: Clinical Outcome and Cost-effectiveness Analyses.
• Review: Immunometabolism, Micronutrients, and Bariatric Surgery: The Use of Transcriptomics and Microbiota-Targeted Therapies.
• Does Postoperative Oral and Intestinal Microbiota Correlate with the Weight-Loss Following Bariatric Surgery?—A Cohort Study.

Drugs

• FDA Approves Saxenda® for the Treatment of Obesity in Adolescents Aged 12-17.
• Commentary: Pfizer COVID Vaccine: Equally Effective with Obesity.
• The Potential of Resveratrol to Act as a Caloric Restriction Mimetic Appears to Be Limited: Insights from Studies in Mice.
• Enoxacin Induces Oxidative Metabolism and Mitigates Obesity by Regulating Adipose Tissue MiRNA Expression.

Food & Diet

• Meta-analysis of RCTs: The Impact of Low Advanced Glycation End Products Diet on Metabolic Risk Factors.
• Ultra-processed Food Consumption and Indicators of Obesity in the United Kingdom Population (2008-2016).
• Effect of a Low-Fat Vegan Diet on Body Weight, Insulin Sensitivity, Postprandial Metabolism, and Intramyocellular and Hepatocellular Lipid Levels in Overweight Adults.
• Longer Time Spent at Home During COVID-19 Pandemic Is Associated with Binge Drinking Among US Adults.
• Metabolic Syndrome Features and Excess Weight Were Inversely Associated with Nut Consumption After 1-Year Follow-Up in the PREDIMED-Plus Study.
• Enhanced Weight and Fat Loss from Long-term Intermittent Fasting in Obesity-prone, Low-fitness Rats.

Caloric and Dietary Restriction

• A Hypoenergetic Diet with Decreased Protein Intake Does Not Reduce Lean Body Mass in Trained Females.
• Review: Still Living Better Through Chemistry: An Update on Caloric Restriction and Caloric Restriction Mimetics as Tools to Promote Health and Lifespan.

Exercise & Physical Activity

• Maternal BMI, Change in Weight Status from Childhood to Late Adulthood and Physical Activity in Older Age.
• Moderate-to-vigorous Physical Activity Duration Is More Important Than Timing for Physical Function in Older Adults.

Economics & Sociology

• Social Determination, Health Selection or Indirect Selection? Examining the Causal Directions between Socioeconomic Status and Obesity in the Chinese Adult Population.
• Economic Preferences and Obesity: Evidence from a Clinical Lab-in-Field Experiment. (PDF)

Epidemiology

• Increases in Prepregnancy Obesity: United States, 2016–2019.
• Height and Body-mass Index Trajectories of School-aged Children and Adolescents from 1985 to 2019 in 200 Countries and Territories.
• Examining the Obesity Paradox: A Moderating Effect of Fitness on Adipose Endocrine Function in Older Adults.
• Sex Differences in the Risk of Coronary Heart Disease Associated with Type 2 Diabetes.

Psychology & Neuroscience

• Narrative review: Sleep Extension: A Potential Target for Obesity Treatment.
• Higher HbA1c Levels Associate with Lower Hippocampal Serotonin Transporter Availability in Non-diabetic Adults with Obesity.

Equity and Disparities

• The Impacts of Racism and Bias on Black People Pursuing Careers in Science, Engineering, and Medicine: Proceedings of a Workshop.
• Food over Fear: Overcoming Barriers to Connect Latinx Immigrant Families to Federal Nutrition and Food Programs.
• Income-based Inequality of Adolescent Obesity in Australia.
• Obesity, Comorbidities, and Treatment Selection in Black and White Women with Early Breast Cancer.
• Weighing the Influence of Race and Obesity on Outcomes in Patients with Early-stage Breast Cancer.
• Trends in Hypertension Clinical Trials Focused on Interventions Specific for Black Adults.

Stigma

• Does Promoting Positive Body Image to a Friend Affect One’s Own Positive Body Image?
• Attitudes and Beliefs in Swedish Midwives and Obstetricians Towards Obesity and Gestational Weight Management.
• Body Appreciation and Appearance Evaluation in Individuals with Obesity Compared to Individuals with Normal-weight: Findings from a Representative German Population Sample.

Policy Related

• State of Obesity 2020: Better Policies for a Healthier America Congressional Briefing.
• Global Epidemics of Obesity and Diabetes: A Renewed Call for Action. (PDF)

Intergenerational Effects

• Moving Down the Energy Ladder: Average In-utero Temperature and Fuel Choice in Adulthood. (PDF)
• Maternal Obesity Is Associated with a Sex-specific Epigenetic Programming in Human Neonatal Monocytes.
• Parental Consumption of Ultra-processed, High-fat Products Has No Association with Childhood Overweight/obesity: An Epidemiological Study Among 10–12-years-old Children in Greece.
• Maternal GDM Status, Genetically Determined Blood Glucose, and Offspring Obesity Risk: An Observational Study.

Ecology, Evolution, & Energetics

• RCT: Nitrogen Recycling Buffers Against Ammonia Toxicity from Skeletal Muscle Breakdown in Hibernating Arctic Ground Squirrels.
• Blood as Fuel: The Metabolic Cost of Pedestrian Locomotion in Rhodnius Prolixus.
• Energetic Scaling Across Different Host Densities and Its Consequences for Pathogen Proliferation.
• Urbanization-driven Climate Change Increases Invertebrate Lipid Demand, Relative to Protein—A Response to Dehydration.

Methods

• Measuring Perceptions of Social Environments for Walking: A Scoping Review of Walkability Surveys.
• Development of a National Dietary Behaviors Questionnaire for EFNEP Adult Participants.

Mathematical and Quantitative

• Modeling Obesity in Norway (The MOON Study): A Decision-Analytic Approach—Prevalence, Costs, and Years of Life Lost.
• A Health Inequality Impact Assessment from Reduction in Overweight and Obesity.
• Optimal Speed in Thoroughbred Horse Racing.
• Risk Prediction Model of Gestational Diabetes Mellitus Based on Nomogram in a Chinese Population Cohort Study.

Commentary

• Lonely Brains Crave People Like Hungry Brains Crave Food.
• Do Cooler Temperatures Really Help with Weight Loss?
• Fruit and Cocoa Flavanols Improve Mental Agility in Human Study.
• Adult Obesity and Its Complications a Pediatric Disease?
• Lipoprotein (a) and Diabetes Mellitus Causes and Consequences.
• Promoting Regular Exercise as a Path to Obesity Treatment. (PDF)
• Liver Fat Storage Pathways Methodologies and Dietary Effects.
• "Fat poets speak: poetry about (some) fat women’s experiences with oppression."

General

• Questionable Utility of the Relative Risk in Clinical Research: A Call for Change to Practice.
• Photosynthesis: On the Art of Stealing Chloroplasts.
• ‘It Will Change Everything’: DeepMind’s AI Makes Gigantic Leap in Solving Protein Structures.
• Vaccines for a Common Pet Problem Could Help Save This Big Cat from Extinction.
• Science News in Brief: from Lizards Re-evolving Legs to How Octopuses Taste with Their Arms.
• Preprint: RCT: Effect of Vitamin D3 Supplementation vs Placebo on Hospital Length of Stay in Patients with Severe COVID-19.
• Folic Acid Supplementation in the Gestational Phase of Female Rats Improves Age-related Memory Impairment and Neuroinflammation in Their Adult and Aged Offspring.
• Peer Review: Implementing a "publish, then review" model of publishing.

Video & Audio

• Webinar: The Place of Nutrition in Medical Education.
• Video: Probiotics: The Friendly Bacteria.
• Podcast: Gerald Shulman, M.D., Ph.D.: A Masterclass on Insulin Resistance—molecular Mechanisms and Clinical Implications.

Announcements

• IU Bloomington leads nationwide study into COVID-19 infection, reinfection, immunity backed by philanthropic investment.
• Society for Nutrition Education and Behavior Is Accepting Abstracts.
• Workshop: Promising Practices and Innovative Programs in the Responsible Conduct of Research.
• The Department of Environmental and Occupational Health at Indiana University School of Public Health-Bloomington (SPH-B) Invites Applications to Join the Faculty of the Department of Environmental and Occupational Health.
• IU Bloomington School of Public Health to Offer New Advanced Degrees in Biostatistics in Next Academic Year.