Featured

• RCT: "in physically inactive men with BMI ≥25 kg/m2, consuming ~14,500 kcal as donuts over 4 weeks did not adversely affect body weight and body fat, or several markers of cardiometabolic risk."
• Systematic Review: Health Effects of Increasing Protein Intake Above the Current Population Reference Intake in Older Adults.
• Two Splendid Books for Gifting at the Holidays - One on Food History, One on Obesity.
• Is Obesity/Adiposity-Based Chronic Disease Curable: The Set Point Theory, the Environment, and Second Generation Medications.

Headline vs Study

• Headline: "Prunes may be the secret weapon to prevent holiday weight gain."
• Study: In RCT, "There was no significant difference in mean weight loss between the [prune and control] groups when measured over 12 weeks" and no mention of holidays.

Contrary or Null Findings

• Low Variability of Plant Protein Intake in the CKiD Cohort Does Not Demonstrate Changes in Estimated GFR nor Electrolyte Balance.
• RCT: Ursolic Acid Does Not Change the Cytokine Levels Following Resistance Training in Healthy Men.
• RCT: One Week of Low or Moderate Doses of Caffeinated Coffee Consumption Does Not Induce Tolerance to the Acute Effects of Caffeine on Sprint Performance.
• "Lifelong soya feeding does not increase lifespan in healthy mice."
• High Sucrose Diet Does Not Impact Spatial Cognition in Rats Using Advanced Touchscreen Technology.
• Neighborhood Walkability Is Not Associated with Attaining Recommended Physical Activity in a Behavioral Weight Loss Trial Testing Remotely Delivered Feedback Messages.
• RCT: Egg and Saturated Fat Containing Breakfasts Have No Acute Effect on Acute Glycemic Control in Healthy Adults.
• RCT: Introducing Dietary Self-Monitoring to Undergraduate Women Via a Calorie-Counting App Has No Effect on Mental Health or Health Behaviors.

Basic

• Glycogen Metabolism Links Glucose Homeostasis to Thermogenesis in Adipocytes.
• Dietary Induction and Reversal of Obesity and Insulin Resistance Is Associated with Changes in Fgf21 DNA Methylation in Liver of Mice.
• The Effect of General Adiposity and Central Body Fat Distribution on the Circulating Metabolome: A Multi-Cohort Non-Targeted Metabolomics Observational and Mendelian Randomization Study.
• CRISPR-Enhanced Human Adipocyte Browning as Cell Therapy for Metabolic Disease.
• RIG-I Deficiency Promotes Obesity-Induced Insulin Resistance.
• Mucin Secretory Action of Capsaicin Prevents High Fat Diet-Induced Gut Barrier Dysfunction in C57BL/6 Mice Colon.
• β3-Adrenergic Receptor Downregulation Leads to Adipocyte Catecholamine Resistance in Obesity.

Scientific Rigor & Scholarly Dialogue

• Article: Effects of Exercise Type and Intensity on Visfatin and the Metabolic Syndrome in Obesity.
• Letter: For the Manuscript: Effects of Exercise Type and Intensity on Visfatin and the Metabolic Syndrome in Obesity.
• Reply: To Letter to the Editor: Effects of Exercise Type and Intensity on Visfatin and the Metabolic Syndrome in Obesity.

Clinical

• Hypoglycemic and Hyperglycemic Crises Among U.S. Adults with Diabetes and End-Stage Kidney Disease: Population-Based Study, 2013–2017.
• Prevalence and Incidence of Microvascular and Macrovascular Complications over 15 Years Among Patients with Incident Type 2 Diabetes.
• Normal Weight Obesity Is Associated with Hypercholesterolemia and Low Muscle Mass in Persons Living with HIV on Antiretroviral Treatment.
• Insulin Resistance Persists Despite a Metabolically Healthy Obesity Phenotype.

Children and Adolescents

• Developmental Trajectories of BMI Since Childhood and Health-Related Quality of Life in Young Adulthood.
• The Other Pandemic: A Conceptual Framework and Future Research Directions of Junk Food Marketing to Children and Childhood Obesity.
• Does Obesity-Associated Insulin Resistance Affect Brain Structure and Function of Adolescents Differentially by Sex?

Surgery

• IL-27 Signalling Promotes Adipocyte Thermogenesis and Energy Expenditure.
• The Effect of Gastric Sleeve Resection on Menstrual Pattern and Ovulation in Premenopausal Women with Classes III-IV Obesity.
• Prior Bariatric Surgery Is Associated with a Reduced Risk of Poor Outcomes in COVID-19: Propensity Matched Analysis of a Large Multi-Institutional Research Network.
• Is Hypertension Despite Use of Two or More Anti-Hypertensive Medications for Patients with a BMI < 40 Kg/m 2 Justified for Eligibility for Bariatric Surgery?

Drugs

• RCT: Comparative Analysis of the Effects of Fish Oil and Fenofibrate on Plasma Metabolomic Profiles in Individuals with Overweight and Obesity.
• Anti-Obesity Drug Discovery: Advances and Challenges.
• Evaluation of the Anti-Obesity Potential of Polyphenols Through Pancreatic Lipase Inhibition.

Food & Diet

• RCT: Hypocaloric Diet with Lower Meal Frequency Did Not Affect Weight Loss, Body Composition and Insulin Responsiveness, but Improved Lipid Profile.
• Total Polyunsaturated Fatty Acid Intake and the Risk of Non-Alcoholic Fatty Liver Disease in Chinese Han Adults: A Secondary Analysis Based on a Case–Control Study.
• Review: Curcumin Supplementation Improves Biomarkers of Oxidative Stress and Inflammation in Conditions of Obesity, Type 2 Diabetes and NAFLD: Updating the Status of Clinical Evidence.
• Zeaxanthin Ameliorates Obesity by Activating the β3-Adrenergic Receptor to Stimulate Inguinal Fat Thermogenesis and Modulating the Gut Microbiota.
• Three in One: The Potential of Brassica By-Products Against Economic Waste, Environmental Hazard, and Metabolic Disruption in Obesity.

Caloric and Dietary Restriction

• G3PP/PGP: A Novel Calorie Restriction Enzyme in C. elegans.
• The Ups and Downs of Caloric Restriction and Fasting: From Molecular Effects to Clinical Application.
• No Significant Effect of the Individual Chronotype on the Result of Moderate Calorie Restriction for Obesity—A Pilot Study.

Exercise & Physical Activity

• Combined Association of Skeletal Muscle Mass and Grip Strength with Cardiovascular Diseases in Patients with Type 2 Diabetes.
• Time-Of-Day Moderate-To-Vigorous Physical Activity and All-Cause Mortality in Individuals with Type 2 Diabetes.
• RCT: Comparison of High Intensity Interval Training with Standard Cardiac Rehabilitation on Vascular Function.
• RCT: Type of Self-Talk Matters: Its Effects on Perceived Exertion, Cardiorespiratory, and Cortisol Responses During an Iso-Metabolic Endurance Exercise.

Economics & Sociology

• Effect of Online Reviews and Offline Cues on Consumer's Restaurant Selection: A Conceptual Model and Research Agenda. (pdf)
• Perceptions of Weight Loss in Older Adults Following a 6-Month Weight Loss Program.
• The Double Burden of Being a Woman and Having Obesity: Evidence from the Chilean Labor Market.
• Seasoned Socialism: Gender and Food in Late Soviet Everyday Life, Edited by Anastasia Lakhtikova, Angela Brintlinger and Irina Glushchenko.
• How Weight and Body Size Affect Learning: A Qualitative Exploration of Experiences in Secondary School.

Epidemiology

• Drive for Thinness in Adolescents Predicts Greater Adult BMI in the Growth and Health Study Cohort over 20 Years.
• Food Insecurity Is Associated with Diarrhea, Respiratory Illness, and Stunting but Not Underweight or Obesity in Low-Resource New Delhi Households.
• Obesity and Anterior Abdominal Gunshot Wounds: A Cushion Effect.
• Is High Dietary Quality the Real Fountain of Youth?

Psychology & Neuroscience

• Brain Responses to Glucose Ingestion are Greater in Children Than Adults and are Associated with Overweight and Obesity.
• Review: Memory and Eating: A Bidirectional Relationship Implicated in Obesity.
• GABAergic Basal Forebrain Projections to the Periaqueductal Gray Promote Food Consumption, Reward and Predation.
• Momentary Predictors of Dietary Lapse from a Mobile Health Weight Loss Intervention.
• Food Olfactory Cues Reactivity in Individuals with Obesity and the Contribution of Alexithymia.

Equity and Disparities

• Systematic Review: Looking for Crumbs in the Obesity Forest: Anti-Obesity Interventions and Obesity-Associated Cardiometabolic Traits in the Mexican Population.
• Gender Differences in the Development of Childhood Obesity in Young Teenagers in Murcia, Spain.
• Prevalence and Contributing Factors to Recurrent Binge Eating and Obesity Among Black Adults with Food Insufficiency: Findings from a Cross-Sectional Study from a Nationally-Representative Sample.

Stigma

• Systematic Review: Weight Stigma and Obesity Related Policies.
• An Examination of the Factor Structure of the Goldfarb Fear of Fat Scale in Clinical and Non-Clinical Samples of Polish Women.

Policy Related

• Patients Undergoing Bariatric Surgery: A Special Risk Group for Lifestyle, Emotional and Behavioral Adaptations During the COVID-19 Lockdown.
• Warning Labels and Interpretive Nutrition Labels: Impact on Substitution between Sugar and Artificially Sweetened Beverages, Juice and Water in a Real-World Selection Task.
• Bariatric Surgery Is Booming, as Patients with Obesity Worry About Their Covid-19 Risks.

Intergenerational Effects

• Impact of Maternal Obesity on Neonatal Heart Rate and Cardiac Size.
• Birth Weight and Postnatal Weight Gain as Predictors of Abdominal Adiposity in Childhood and Adolescence: A Cohort Study in Northeast Brazil.
• Association of Parental Prepregnancy BMI with Neonatal Outcomes and Birth Defect in Fresh Embryo Transfer Cycles: A Retrospective Cohort Study.

Ecology, Evolution, & Energetics

• Impact of Follicular Menstrual Phase on Body Composition Measures and Resting Metabolism.
• What’s Sweeter Than Honey to These Bees? Rotting Meat. Special Germs in Their Guts Help the Bees Digest Flesh.
• Body Mass and Tail Girth Predict Hibernation Expression in Captive Dwarf Lemurs.
• Seasonal Variations in the Intermediate Metabolism in South American Tree-Frog Boana pulchella.

Methods

• Applications of Complex Systems Models to Improve Retail Food Environments for Population Health: A Scoping Review.
• Recommendations for the Use of the Veggie Meter® for Spectroscopy-Based Skin Carotenoid Measurements in the Research Setting.

Commentary

• Lessons Learned for Obesity Prevention and Care from Five Integrated Programs.
• Most Vegan Thanksgiving Ever? Not Exactly.
• Twin Views of Obesity in Conflict.
• An Alternative Approach to Obesity Treatment: Intermittent Fasting.
• Childhood Obesity: Are New Treatment Centres the Solution?
• Nothing Ventured, Nothing Gained: Does This Apply to Obesity in Young People?
• Uncomfortably Important: Children, Obesity, and COVID.
• Energy Compensation and Metabolic Adaptation: “The Biggest Loser” Study Reinterpreted.

General

• Fetomaternal Microchimerism and Genetic Diagnosis: On the Origins of Fetal Cells and Cell-Free Fetal DNA in the Pregnant Woman.
• New Directions in Research on Aging.
• Question the ‘Lab Leak’ Theory. But Don’t Call It a Conspiracy.
• At the Dawn of Life, Heat May Have Driven Cell Division.
• Dismissing “Don’t Know” Responses to Perceived Risk Survey Items Threatens the Validity of Theoretical and Empirical Behavior-Change Research.
• Preprint: Harnessing the Power of Sex Differences: What a Difference Ten Years Did Not Make.
• Letter: Multiple Comparisons and Inappropriate Statistical Testing Lead to Spurious Sex Differences in Gene Expression.
• Response: Reply To: Multiple Comparisons and Inappropriate Statistical Testing Lead to Spurious Sex Differences in Gene Expression.
• Pre-Print: Ten Simple Rules in Good Research Practice for Early Career Researchers.
• Randomistas Vs. Contestistas.
• Misinformation Fuelled by ‘Tsunami’ of Poor Research, Says Science Prize Winner.

Announcements

• IU Virtual Event: Dr. Anthony Fauci to Receive Ryan White Award, Take Part in Virtual Ceremony.
• Now Seeking Applications for American Society for Nutrition’s 2022 Science Policy Fellowship. Due December 17.
• IU Bloomington School of Public Health Is Recruiting Tenure-Track Faculty in Every Department! A Sampling of Opportunities Is Here, but Even Departments Not Yet Listed are Recruiting.
• Nutrition Science Non-Tenure-Track Search: Clinical Full-Associate-Assistant Professor; Senior Lecturer or Lecturer.
• Nutrition Science Tenure/Tenure-Track Search: Full Professor/Associate-Assistant Professor.