Featured

• Commentary: “Breakfast doesn't have much to do with weight loss."
• The Effects of Dietary Saturated Fat Source on Weight Gain and Adiposity are Influenced by Both Sex and Total Dietary Lipid Intake in Zebrafish.
• To Be Energy-Efficient, Brains Predict Their Perceptions.
• The Cost of Reproduction in a Cooperatively Breeding Mammal: Consequences of Seasonal Variation in Rainfall, Reproduction, and Reproductive Suppression.

Headline vs Study

• Headline: Adding Juice to Baby's Diet May Increase Risk for Obesity, Study Finds.
• Study: Predictors of Age at Reported Juice Introduction and Associations with Subsequent Reported Beverage Intake in Early and Middle Childhood. Obesity Not Reported.

Contrary or Null Findings

• RCT: "The current study was unable to detect a significant effect of the OBEST application as an adjunct tool to the standard treatment on reducing weight in [children and adolescents with obesity]."
• RCT: "Although metformin and lifestyle modification prevented diabetes, neither strategy reduced all-cause, cancer, or cardiovascular mortality rates."
• RCT: No Apparent Effects of a Viscous, Superabsorbent Hydrogel on Appetite, Energy Intake, or Fecal Excretion in Overweight Adults.
• Genosets for APOE and CYP7A1-Rs3808607 Variants Do Not Predict Low-Density Lipoprotein Cholesterol Lowering upon Intervention with Plant Sterols in an RCT.
• RCT: "ALA supplementation with camelina oil did not improve vascular function but adversely affected glucose metabolism in hypertensive patients with metabolic syndrome."
• "Contrary to expectations, a peer-created ego-climate contributed positively to three life skills and total life skills" in childhood sports programs.
• RCT: "...probiotics have no advantage over lifestyle modification for improving obesity-associated metabolic derangement in children."
• "No significant associations between PCB-153, PFOA, PFOS, or pentaPBDEs with childhood BMI were found in meta-analyses."

Basic

• Leptin Receptor Defect with Diabetes Causes Skeletal Muscle Atrophy in Female Obese Zucker Rats Where Peculiar Depots Networked with Mitochondrial Damages.
• Asparagine Reinforces MTORC1 Signaling to Boost Thermogenesis and Glycolysis in Adipose Tissues.
• BAd-CRISPR: Inducible Gene Knockout in Interscapular Brown Adipose Tissue of Adult Mice.
• A Novel Partial PPARγ Agonist Has Weaker Lipogenic Effect in Adipocytes and Stimulates GLUT4 Translocation in Skeletal Muscle Cells Via AMPK-Dependent Signaling.
• Parental High-Fat High-Sugar Diet Programming and Hypothalamus Adipose Tissue Axis in Male Wistar Rats.

Scientific Rigor & Scholarly Dialogue

• Expression of Concern: Differential Effects of Growth Hormone and Alfa Calcidol on Trabecular and Cortical Bones in Hypophysectomized Rats.
• Article: Effect of Vitamin D3 on Severe Asthma Exacerbations in Children with Asthma and Low Vitamin D Levels: The VDKA RCT.
• Critique: "A study of [children with asthma], most of them Black, shows how a common clinical trial design can expose vulnerable participants to serious risks"
• Critique of critique: Misleading Portrayal of Children’s Asthma Study.
• Response from study author: Accurately Assessing Children’s Asthma Study.
• Editor’s note: Regarding the Two Letters.
• Blog Post: The Importance of Careful Use of Comparative Terms in Quantitative Arguments in Science Journalism.
• PubPeer Comment: Summarizing the Defense of the Study.

Clinical

• Novel Adiposity and Biochemical–Anthropometric Indices to Identify Cardiometabolic Risk and Metabolic Syndrome in Mexican Adults.
• Trends in Obesity Prevalence Among Adults Aged 18 Through 25 Years, 1976-2018.
• Effectiveness of Anti-Obesity Medications Approved for Long-Term Use in a Multidisciplinary Weight Management Program: A Multi-Center Clinical Experience.

Children and Adolescents

• Pediatric Weight Management Through MHealth Compared to Face-To-Face Care: Cost Analysis of an RCT.
• Birth Weight, Adult Weight, and Cardiovascular Biomarkers: Evidence from the Cardiovascular Young Finns Study.
• Adolescent BMI and Changes in Pre-Pregnancy BMI in Relation to Risk of Gestational Diabetes.
• The Relationship between BMI and Children’s Mathematics Performance.

Surgery

• One Year Follow-Up of Taste-Related Reward Associations with Weight Loss Suggests a Critical Time to Mitigate Weight Regain Following Bariatric Surgery.
• Colorectal Cancer After Bariatric Surgery (Cric-Abs 2020): Sicob (Italian Society of Obesity Surgery) Endorsed National Survey.
• Radiographic Measurement of Gastric Remnant Volume After Laparoscopic Sleeve Gastrectomy: Assessment of Reproducibility and Correlation with Weight Loss.
• Body Composition, Basal Metabolic Rate and Leptin in Long-Term Weight Regain After Roux-En-Y Gastric Bypass are Similar to Pre-Surgical Obesity.

Drugs

• Novel Noninvasive Approaches to the Treatment of Obesity: From Pharmacotherapy to Gene Therapy.
• Endocrine Disruptors, Obesity, and Prostate Cancer: Cell Fate Analysis.
• RCT: Once-Weekly Cagrilintide for Weight Management in People with Overweight and Obesity.
• Liraglutide for Weight Management in the Real World: Significant Weight Loss Even If the Maximal Daily Dose Is Not Achieved.

Food & Diet

• Life Habits of Postmenopausal Women: Association of Menopause Symptom Intensity and Food Consumption by Degree of Food Processing.
• The Effects of Blueberry Phytochemicals on Cell Models of Inflammation and Oxidative Stress.
• Diets for Weight Management in Adults with Type 2 Diabetes: An Umbrella Review of Published Meta-Analyses and Systematic Review of Trials of Diets for Diabetes Remission.
• Sugar-Sweetened Beverage Consumption Among Adults in Rural Appalachia.

Caloric and Dietary Restriction

• RCT: Short-Term Pre-Operative Protein Caloric Restriction in Elective Vascular Surgery Patients.
• Short Term Caloric Restriction and Biofeedback Enhance Psychological Wellbeing and Reduce Overweight in Healthy Women.
• Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Cancer Patients.

Exercise & Physical Activity

• RCT: Estrogen Modulates Metabolic Risk Profile After Resistance Training in Early Postmenopausal Women.
• Meta-Analysis: Overall Effect of MHealth Physical Activity Interventions for Weight Loss and the Moderating Effect of Behavioral Change Theories, Techniques, and Mobile Technologies.
• Meta-Analysis: Calorie Restriction with Exercise Intervention Improves Inflammatory Response in Adults with Overweight and Obesity.
• The Exercise-Induced Improvement in Insulin-Stimulated Glucose Uptake by Rat Skeletal Muscle Is Absent in Male AS160-Knockout Rats, Partially Restored by Muscle Expression of Phosphomutated AS160, and Fully Restored by Muscle Expression of Wildtype AS160.

Economics & Sociology

• The Associations of Socioeconomic Status and Financial Strain with Restrained and Emotional Eating Among 42-Year-Old Women and Men.
• The Role of Socioeconomic Status in Adherence to the Mediterranean Diet and BMI Change.
• Longer-Term Impacts of the Oakland, California, Sugar-Sweetened Beverage Tax on Prices and Volume Sold at Two-Years Post-Tax.

Epidemiology

• LDL-Cholesterol Trajectories and Statin Treatment in Finnish Type 2 Diabetes Patients: A Growth Mixture Model.
• Obesity and Cancer Death in White and Black Adults: A Prospective Cohort Study.
• Prevalence of Type 2 Diabetes by Age, Sex and Geographical Area Among Two Million Public Assistance Recipients in Japan: A Cross-Sectional Study Using a Nationally Representative Claims Database.

Psychology & Neuroscience

• Interoception and Obesity.
• AgRP/NPY and POMC Neurons in the Arcuate Nucleus and Their Potential Role in Treatment of Obesity.
• Systematic Review: Screening for Mild Cognitive Impairment in People with Obesity.
• Meta-Analysis: Self-Reported Eating Speed Is Associated with Indicators of Obesity in Adults.

Equity and Disparities

• Racial/Ethnic Disparities in Parent Activation: Implications for Developing Interventions Addressing Early Childhood Obesity.
• The Determinants of Racial Disparities in Obesity: Baseline Evidence from a Natural Experiment.
• Effects of Diabetes and Obesity on Cognitive Impairment and Mortality in Older Mexicans.
• Leading Our Way: Urban and Rural Indigenous Diabetes and Obesity Wellness Programs.

Stigma

• Systematic Review: Is Weight Stigma Associated with Physical Activity?
• Incorporating Obesity and Weight Bias Training Improved Attitudes of Hospital Staff Towards People with Obesity in Alberta.
• Intuitive Eating Buffers the Link between Internalized Weight Stigma and BMI in Stressed Adults.

Policy Related

• Policies to Restrict Unhealthy Food and Beverage Advertising in Outdoor Spaces and on Publicly Owned Assets: A Scoping Review of the Literature.
• Diet, Nutrition, Obesity, and Their Implications for COVID-19 Mortality: Development of a Marginalized Two-Part Model for Semicontinuous Data.

Intergenerational Effects

• Meta-Analysis: Prenatal Exposure to Persistent Organic Pollutants and Childhood Obesity.
• Maternal BMI, Offspring BMI, and Blood Pressure at 18 Years: A Causal Mediation Analysis.
• Changes in Fathers’ BMI, Sleep, and Diet from Prebirth to 12 Months Postbirth: Exploring the Moderating Roles of Parenthood Experience and Coparenting Support.
• Perinatal Socio-Behavioral and Obstetric Predictors of Metabolically Healthy and Unhealthy Obesity in Adult Offspring.

Ecology, Evolution, & Energetics

• Sex Differences in the Response to Circadian Disruption in Diurnal Sand Rats.
• The Structure and Function of Gut Microbiomes of Two Species of Sea Urchins, Mesocentrotus Nudus and Strongylocentrotus Intermedius, in Japan.

Methods

• Measurement of Physical Activity Self-Efficacy in Adults with Obesity: A Latent Variable Approach to Explore Dimensionality, Temporal Invariance, and External Validity.
• Comparison of Pancreatic Fat Content Measured by Different Methods Employing MR MDixon Sequence.
• Preparation of Methodological Systematic Reviews in Nutrition Science.

Mathematical and Quantitative

• A Simple Mathematical Model Simulating Individual Weight Based on Daily Diet Menu.
• Modeling Growth Curves for Epidemiology.

Commentary

• Obesity May Trigger Development of Cells That Break Down Bones Holding the Teeth, Study Shows.
• More Anti-Obesity Medicine Progress with Cagrilintide.
• How a Narrow Definition of Healthy Diverges from Health.
• New Polling: Medicare Lags Behind on Obesity Care.
• Conceptualizing Food Insecurity Among Older Adults: Development of a Summary Indicator in the National Health and Aging Trends Study.
• The Dietary Guidelines for Americans (2020–2025): Pulses, Dietary Fiber, and Chronic Disease Risk—A Call for Clarity and Action.
• BMI Centiles for South Asian Children: Do They Need Reconsideration?

General

• Molecular Reconstruction of Recurrent Evolutionary Switching in Olfactory Receptor Specificity.
• Structural Racism and Its Pathways to Asthma and Atopic Dermatitis.
• Disturbed Retinoid Metabolism upon Loss of Rlbp1a Impairs Cone Function and Leads to Subretinal Lipid Deposits and Photoreceptor Degeneration in the Zebrafish Retina.
• Mediation Analysis of Social Isolation and Mortality by Health Behaviors.
• When No One Is Watching: Ecological Momentary Assessment to Understand Situated Social Robot Use in Healthcare.
• Within-Person Longitudinal Associations between Electronic Nicotine Delivery Systems Use and Smoking Cessation Efforts Among U.S. Continuing Adult Cigarette Smokers.
• Age Varying Polygenic Effects on Alcohol Use in African Americans and European Americans from Adolescence to Adulthood.
• Possible Gender Influence in the Mechanisms Underlying the Oxidative Stress, Inflammatory Response, and the Metabolic Alterations in Patients with Obesity and/or Type 2 Diabetes.
• A Billion-Dollar Donation: Estimating the Cost of Researchers' Time Spent on Peer Review.

Video & Audio

• Webinar: Metabolic Adaptations: The Physiology of Cold Acclimatization and Exercise in Rodent Models.

Announcements

• Colloquium Nov 29: Geographical Indications and Sustainable Food Systems. (pdf)
• IU Bloomington Ranks High in U.S. News List of 'Best Global Universities'.
• IU Bloomington School of Public Health Is Recruiting Tenure Track Faculty in Every Department! A Sampling of Opportunities Is Here, but Even Departments Not Yet Listed are Recruiting.
• Non-Tenure-Track: Clinical Full/Associate/Assistant Professor; Senior Lecturer/Lecturer Search.
• Nutrition Science Tenure-Track/Tenure: Full/Associate/Assistant Professor Search.
• The Center for Research on Race and Ethnicity in Society (CRRES) at Indiana University Bloomington Invites Applications for Up to Two CRRES Postdoctoral Fellowships.