Featured

• A Sad Loss for the Obesity Research Community: Dr. Randall "Randy" Lee Mynatt passed away in Baton Rouge, LA on November 10, 2021.
• As in Humans, Measuring Energy Intake in Free-Living Whales Proves Challenging: Biologists Vastly Underestimated How Much Whales Eat and Poop.
• RCT: Cognitive Response to Testosterone Replacement Added to Intensive Lifestyle Intervention in Older Men with Obesity and Hypogonadism.
• Women with Long COVID May Need Targeted Rehab to Counter Problems with Physical Activity Tolerance.

Headline vs Study

• Headline: Scientists May Have Found the Perfect Bedtime to Keep Hearts Healthy.
• Study: Associations between Arbitrarily Discretized Accelerometer-Derived Sleep Onset Timing and Cardiovascular Disease Incidence.
• SciCom Commentary: Careful! Health News Headlines Can Be Deceiving.

Contrary or Null Findings

• RCT: "Five years of supervised exercise training in older adults had little effect on cardiovascular risk profile and did not reduce cardiovascular events."
• "Although we expected rapid growth to induce developmental costs, neither instantaneous growth rates nor the duration of larval growth were related to developmental stability in the adult."
• "Contrary to what was expected, in the three marine populations, the SFA and MUFA levels showed opposite correlations (negative and positive, respectively) with habitat temperatures…in finless porpoises …"
• RCT: Post-Exercise Cold Water Immersion Does Not Improve Subsequent 4-Km Cycling Time-Trial Compared with Passive and Active Recovery in Normothermia.
• N-Acetylcysteine Supplementation Did Not Reverse Mitochondrial Oxidative Stress, Apoptosis, and Inflammation in the Salivary Glands of Hyperglycemic Rats.
• Obesity Does Not Protect from Subarachnoid Hemorrhage: Pooled Analyses of 3 Large Prospective Nordic Cohorts.
• RCT: A Protein-Supplemented Very-Low-Calorie Diet Does Not Mitigate Reductions in Lean Mass and Resting Metabolic Rate in Subjects with Overweight or Obesity.
• RCT: "At the six-month intervention endpoint (n=862) there were no statistically significant differences between students in intervention or control schools for mean daily intake of SSBs …percentage daily energy from SSBs …or for secondary outcomes."

Basic

• Hepatocyte-Specific Fibroblast Growth Factor 21 Overexpression Ameliorates High-Fat Diet-Induced Obesity and Liver Steatosis in Mice.
• A Neural Circuit Integrates Pharyngeal Sensation to Control Feeding.
• The KRAB Domain-Containing Protein ZFP961 Represses Adipose Thermogenesis and Energy Expenditure Through Interaction with PPARα.
• Dietary Macronutrient Imbalances Lead to Compensatory Changes in Peripheral Taste Via Independent Signaling Pathways.

Scientific Rigor & Scholarly Dialogue

• Letter: Systematic Review of Counseling and Behavioral Interventions for Healthy Weight and Weight Gain in Pregnancy from the US Preventive Services Task Force.
• Reply: to letter on "Systematic Review of Counseling and Behavioral Interventions for Healthy Weight and Weight Gain in Pregnancy from the US Preventive Services Task Force."
• Event: The STORK Summit 2022: Moving Toward Better Research Practices in Kinesiology.

Clinical

• Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol.
• Abstract: Higher BMI Is Associated with a Higher Prevalence of Thin-Cap Fibroatheroma in Younger Patients with Type 2 Diabetes Mellitus.
• Metabolic and Genetic Determinants for Progression to Severe Liver Disease in Subjects with Obesity from the UK Biobank.
• Birth with Synthetic Oxytocin and the Risk of Having Overweight or Obesity During Childhood.

Children and Adolescents

• Associations of Dairy Intake with Anthropometric Failure in Children Ages 6 to 23 Mo Consuming Vegetarian Diets and Fulfilling Minimum Dietary Diversity in India.
• RCT: Effectiveness of Mobile Application on Changing Weight, Healthy Eating Habits, and Quality of Life in Children and Adolescents with Obesity.
• Narrative Review: Early Nutrition and Later Excess Adiposity During Childhood.
• How Do Interpersonal Relationships Affect Children's Weight Management? A Qualitative Analysis of Parents' Long-Term Perceptions After Obesity Treatment.
• RCT: Effectiveness of a Multifaceted Intervention for Prevention of Obesity in Primary School Children in China.
• Meta-Analysis: Low Birth Weight and Small for Gestational Age are Associated with Complications of Childhood and Adolescence Obesity.
• Prospective Associations between Leukocyte Telomere Length and Adiposity in Childhood.
• Qualitative Comparative Analysis of Program and Participant Factors That Explain Success in a Micropolitan Pediatric Weight Management Intervention.

Surgery

• Review: Efficacy and Mechanisms of Gastric Volume-Restriction Bariatric Devices.
• Bariatric Surgery Induces a Differential Effect on Plasma Aldosterone in Comparison to Dietary Advice Alone.
• Patients with Low Socioeconomic Status are More Likely to Undergo Sleeve Gastrectomy vs Roux-En-Y Gastric Bypass.
• Meeting Abstract of Meta-Analysis: Protective Role of Bariatric Surgery in Prevalence and Risk of Atrial Fibrillation in Patients with Obesity on Long-Term, with Gradually Waning Effect over a Decade.

Drugs

• Video: GLP-1 Agonists – the Future of Treating Obesity?
• Video: Pharmacotherapy for Obesity.

Food & Diet

• RCT: Increasing Vegetable Intake Decreases Urinary Acidity and Bone Resorption Marker in Adults with Overweight and Obesity.
• Informal Vendors and Food Systems Planning in an Emerging African City.
• Review: Impacts of Essential Amino Acids on Energy Balance.
• The Relationship between Dietary Approaches to Stop Hypertension Diet Adherence and Inflammatory Factors and Insulin Resistance in Women with Overweight and Obesity: A Cross-Sectional Study.
• Review: MUFA in Metabolic Syndrome and Associated Risk Factors: Is MUFA the Opposite Side of the PUFA Coin?
• Reproducibility and Validity of Diet Quality Scores Derived from Food Frequency Questionnaires.

Caloric and Dietary Restriction

• Caloric Restriction Induces Anabolic Resistance to Resistance Exercise.
• The Effect of Caloric Restriction on the Increase in Senescence-Associated T Cells and Metabolic Disorders in Aged Mice.
• Predictors of Clinically Meaningful Gait Speed Response to Caloric Restriction Among Older Adults Participating in Weight Loss Interventions.
• Review: Molecular Mechanisms of Dietary Restriction Promoting Health and Longevity.

Exercise & Physical Activity

• RCT: Effect of Different Kinesio Tape Tensions on Experimentally-Induced Thermal and Muscle Pain in Healthy Adults.
• Systematic Review: The Metabolic Signature of Cardiorespiratory Fitness.
• Home-Based HIIT and Traditional MICT Prescriptions Improve Cardiorespiratory Fitness to a Similar Extent Within an Exercise Referral Scheme for At-Risk Individuals.
• Is Wrist Accelerometry Suitable for Threshold Scoring? A Comparison of Hip-Worn and Wrist-Worn ActiGraph Data in Low-Active Older Adults with Obesity.
• Timing of Objectively-Collected Physical Activity in Relation to Body Weight and Metabolic Health in Sedentary Older People: A Cross-Sectional and Prospective Analysis.

Economics & Sociology

• Cost-Effectiveness of Lipid-Lowering Treatments in Young Adults.
• Associations between Socioeconomic Status and Obesity, Sarcopenia, and Sarcopenic Obesity in Community-Dwelling Older Adults: The Tasmanian Older Adult Cohort Study.
• Abstract: Financial Hardship from Medical Bills Among Non-Elderly Adults with Obesity in the US.
• Meta-Analysis: Health and Financial Costs of Adverse Childhood Experiences in 28 European Countries.

Epidemiology

• Chronic Disease and Where You Live: Built and Natural Environment Relationships with Physical Activity, Obesity, and Diabetes.
• The Impact of Undernutrition on Cognition in Children with Severe Malaria and Community Children: A Prospective 2-Year Cohort Study.
• Demographic and Sociocultural Risk Factors for Adulthood Weight Gain in Hispanic/Latinos: Results from the Hispanic Community Health Study / Study of Latinos (HCHS/SOL).
• Abstract: Morbid Obesity Eliminates the Obesity Paradox in Patients Hospitalized for Heart Failure.
• Trabecular Bone Score and Bone Mineral Density in Postmenopausal Women with Morbid Obesity—A Clinical Paradox.
• Association of Bariatric Surgery with Major Adverse Liver and Cardiovascular Outcomes in Patients with Biopsy-Proven Nonalcoholic Steatohepatitis.
• Risk Associations of Long-Term HbA1c Variability and Obesity on Cancer Events and Cancer-Specific Death in 15,286 Patients with Diabetes - a Prospective Cohort Study.

Psychology & Neuroscience

• BMI and the Risk of Suicidal Ideation and Suicide Attempt Among Youth in 45 Low-And Middle-Income Countries.
• Diminished Insulin Sensitivity Is Associated with Altered Brain Activation to Food Cues and with Risk for Obesity – Implications for Individuals Born Small for Gestational Age.
• Perspective: Advances in Diet-Induced Rodent Models of Metabolically Acquired Peripheral Neuropathy.
• Glycemic Dysregulations are Associated with Worsening Cognitive Function in Older Participants at High Risk of Cardiovascular Disease: Two-Year Follow-Up in the PREDIMED-Plus Study.
• Long Term Metabolic and Inflammatory Effects of Second-Generation Antipsychotics: A Study in Offenders with Mental Disorders.
• Mindful Eating, Body Weight, and Psychological Well-Being in Adolescence.

Equity and Disparities

• Classes of Lifetime Adversities Among Emerging Adult Women by Race/ethnicity and Their Associations with Weight Status in the United States.
• Abstract: Trends in Racial and Ethnic Differences in Adiposity and Association with All-Cause Mortality in Adults in the United States: A 20-Year National Health and Nutrition Examination Survey Analysis, 1999-2018.
• Latino Children's Obesity Risk Varies by Place of Birth: Findings from New York City Public School Youth, 2006–2017.

Stigma

• Meta-Analysis: Weight Stigma and Mental Health in Youth.
• Perceptions of Weight Management: Interviews with Adolescents with Severe Obesity and Their Mothers.
• Qualitative Study: “Do You Find It Normal to Be So Fat?” Weight Stigma in Gym Users with Obesity.

Policy Related

• Evaluation of Changes in Grams of Sugar Sold After the Implementation of the Seattle Sweetened Beverage Tax.
• Restricting the Advertising of High Fat, Salt and Sugar Foods on the Transport for London Estate: Process and Implementation Study.
• Understanding Prevention Networks in a Local Government Area: Insights from a Social Network Analysis Among Western Australian Nutrition, Physical Activity, and Obesity Prevention Programs.
• Editorial: Childhood Obesity Interventions—Going Beyond the Individual.
• Effects of Competing Food Desert Policies on Store Format Choice Among SNAP Participants.
• Scoping Review: Policies to Restrict Unhealthy Food and Beverage Advertising in Outdoor Spaces and on Publicly Owned Assets.

Intergenerational Effects

• Meta-Analysis: Impact of Maternal Pre-Pregnancy BMI on Maternal, Fetal and Neonatal Adverse Outcomes in the Worldwide Populations.
• Meta-Analysis: Prenatal Exposure to Persistent Organic Pollutants and Childhood Obesity.
• Prenatal and Early Childhood Exposure to Lead and Repeated Measures of Metabolic Syndrome Risk Indicators from Childhood to Preadolescence.
• Elevated Anthropometric and Metabolic Indicators Among Young Adult Offspring of Mothers with Pregestational Diabetes: Early Results from the Transgenerational Effect on Adult Morbidity Study.

Ecology, Evolution, & Energetics

• PM10 Exposure Interacts with Abdominal Obesity to Increase Blood Triglycerides: A Cross-Sectional Linkage Study.
• Predicting Novel Candidate Human Obesity Genes and Their Site of Action by Systematic Functional Screening in Drosophila.
• Evaluation of Antioxidant Response and Na+-K+-ATPase Activity in Zebrafish Exposed to Polyethylene Microplastics: Shedding Light on a Physiological Adaptation.
• An Hourglass Mechanism Controls Torpor Bout Length in Hibernating Garden Dormice (PDF).

Methods

• The GLIM Criteria for Nutrition Assessment and Survival Prediction in Older Adult Cancer Patients.
• Review: Artificial Intelligence in Nutrients Science Research.
• Meta-Analysis: Impact of Risk of Generalizability Biases in Adult Obesity Interventions.
• Systematic Review: Modulating Eating Behavior with Transcranial Direct Current Stimulation (tDCS).

Mathematical and Quantitative

• Uncorrected Proof: Comparison of Metabolic States Using Genome-Scale Metabolic Models.
• A Machine Learning Approach to Predict the Trend of Obesity Prevalence at a Global Level.

Commentary

• Guide and Advances on Childhood Obesity Determinants: Setting the Research Agenda.
• Lean Body Mass Level Predicts Cardiac Output in Women.
• Should You Take Aspirin?
• 'Scorn for Scoring Foods for Health'.
• Systematic Review: Breastfeeding: When Will Enough Evidence Be Enough?
• Obesity: Can We Blame It on Cheap Gas?
• Variation in AIN-93G/M Diets Across Different Commercial Manufacturers: Not All AIN-93 Diets are Created Equal.
• Cutting NASH Harms by 88% with Bariatric Surgery.
• Press Release: Bristol Childhood Obesity Clinic Forms Blueprint for National NHS Pilot.

General

• Tick “not”: understanding tick encounters on recreational trails through online reviews.
• RCT: The Effects of a Novel Personal Comfort System on Thermal Comfort, Physiology and Perceived Indoor Environmental Quality, and Its Health Implications - Stimulating Human Thermoregulation Without Compromising Thermal Comfort.
• The Great Organic-Food Fraud: There’s No Way to Confirm That a Crop Was Grown Organically. Randy Constant Exploited Our Trust in the Labels—and Made a Fortune.
• Physical Activity Behavior in the First Month After Mild Traumatic Brain Injury Is Associated with Physiological and Psychological Risk Factors for Chronic Pain.
• Scientists: Don’t Feed the Doubt Machine.
• Campus Food Pantry Use Addresses a Gap Among California Public University Students.
• RCT: High-Intensity Leg Cycling Alters the Molecular Response to Resistance Exercise in the Arm Muscles.
• Event: Data, Rigor, and Reproducibility in Light of Diversity, Equity, and Inclusion.

Video & Audio

• Podcast: 11. Katherine Flegal, PhD: The Obesity Wars and the Politicization of Science.

Announcements

• IU Bloomington School of Public Health Is Recruiting Tenure Track Faculty in Every Department! A Sampling of Opportunities Is Here, but Even Departments Not Yet Listed are Recruiting.
• Non-Tenure-Track: Clinical Full/Associate/Assistant Professor; Senior Lecturer/Lecturer Search.
• Nutrition Science Tenure-Track/Tenure: Full/Associate/Assistant Professor Search.
• The Center for Research on Race and Ethnicity in Society (CRRES) at Indiana University Bloomington Invites Applications for Up to Two CRRES Postdoctoral Fellowships.