Featured

• Determining Energy Expenditure in a Large Seabird Using Accelerometry.
• Glucose-Dependent Insulinotropic Polypeptide Regulates Body Weight and Food Intake Via GABAergic Neurons in Mice.
• RCT: Semaglutide and Cardiovascular Outcomes in Obesity Without Diabetes.

Headline vs Study

• Headline (From the Research Authors): Insecure Renting Ages You Faster Than Owning a Home, Unemployment or Obesity. Better Housing Policy Can Change This.
• Study: Associations between Various Housing, Social, and Health Variables and So-Called 'Epigenetic Aging' from DNA Methylation. Causation Not Established; Policy Not Tested.

Contrary or Null Findings

• RCT: Early Initiation of Metformin Did Not Significantly Reduce Insulin Initiation or Improve Fasting Hyperglycemia at Gestation Weeks 32 or 38.
• "Mitochondrial genes in every study species exhibited evidence of purifying selection, but the strength of selection was greater in short-distance migrants, contrary to our predictions."
• "Contrary to our hypothesis, low BMI had no impact on patient survival" in patients with familial dysautonomia.
• "Although temperatures increased at Mývatn over this period, there was only a slight (non-significant) decrease in midge adult body size, contrary to theoretical expectations."
• "Contrary to our hypothesis, when consumed in combination, evening alcohol consumption interacted with ongoing caffeine consumption such that alcohol partially mitigated the impairments in sleep quantity associated with caffeine (p = 0.032)."
• "Sub-effective doses of glucose plus Ad administered simultaneously to Ad-deficient mice increased contextual fear memory, contrary to independent sub-effective doses" in mice.
• "Contrary to some published trials, our meta-analysis concludes that the use of probiotics in patients with SAP is not effective in reducing the mortality rate, septic complications, and need for operation."
• "Contrary to expectations, higher VAI [visceral adiposity index] levels were associated with higher overall cognitive scores and improved episodic memory scores, while no significant effect was observed on mental status."

Basic

• Antioxidants Green Tea Extract and Nordihydroguaiaretic Acid Confer Species and Strain-Specific Lifespan and Health Effects in Caenorhabditis Nematodes.
• A PPARγ/Long Noncoding RNA Axis Regulates Adipose Thermoneutral Remodeling in Mice.
• Puberty as a DOHaD Programming Window: High-Fat Diet Induces Long-Term Hepatic Dysfunction in Male Rats.
• Hepatic Runx1t1 Improves Body Fat Index After Endurance Exercise in Obese Mice.
• Thromboxane A2/Thromboxane A2 Receptor Axis Facilitates Hepatic Insulin Resistance and Steatosis Through Endoplasmic Reticulum Stress in Non-Alcoholic Fatty Liver Disease.

Scientific Rigor & Scholarly Dialogue

• Retraction: Leukocyte Telomere Length and Obesity in Children and Adolescents: A Systematic Review and Meta-Analysis.
• Correction: Randomized Nutrient Bar Supplementation Improves Exercise-Associated Changes in Plasma Metabolome in Adolescents and Adult Family Members at Cardiometabolic Risk.
• Evaluation of Changes in Dietary Methodology in the National Diet and Nutrition Survey Rolling Programme from Year 12 (2019 to 2020): Stage 2.

Clinical

• RCT: Precision Nutrition Counseling for Service Members at Risk for Metabolic Syndrome.
• Retatrutide Showing Promise in Obesity (and Type 2 Diabetes).
• Pathophysiology of Obesity-Related Infertility and Its Prevention and Treatment by Potential Phytotherapeutics.
• Pentadecanoic Acid (C15:0) Shares Clinically Relevant Cell-Based Activities with Leading Longevity-Enhancing Compounds.

Children and Adolescents

• Association of Physical Activity, Sedentary Behavior, Diet Quality with Adiposity: A Longitudinal Analysis in Children Categorized by Baseline Weight Status.
• Economic Growth and Childhood Malnutrition in Low- and Middle-Income Countries.
• Review: Pediatric Obesity Care Via Telemedicine: Expanding the Path Forward.
• Trends in Prevalence of Breastfeeding Initiation and Duration Among US Children, 1999 to 2018.
• How the Marketing Practices of Commercial Milk Formula Companies Impact Infant Breastfeeding Practices.

Surgery

• Follow-Up Care After Metabolic Surgery – in the North-Eastern Region of Romania.
• Surgical Importance of Belseys Fat in Sleeve Gastrectomy—a Less Visited Topic.
• Weight-Loss Independent Clinical and Metabolic Biomarkers Associated with Type 2 Diabetes Remission Post-Bariatric/Metabolic Surgery.
• Meta-Analysis: Bariatric Surgery for Patients with Overweight/Obesity. A Comprehensive Grading Methodology and Network Metanalysis of RCTs on Weight Loss Outcomes and Adverse Events.

Drugs

• Effect of Obesity on the Pharmacokinetics and Pharmacodynamics of Anticancer Agents.
• Cost-Effectiveness of Antiobesity Drugs for Adolescents with Severe Obesity.

Food & Diet

• RCT: The Effect of Conjugated Linoleic Acid Supplementation on Densitometric Parameters in Women with Overweight and Obesity.
• RCT: Modification of Breakfast Fat Composition Can Modulate Cytokine and Other Inflammatory Mediators in Women.
• Overflowing Tables: Changes in the Energy Intake and the Social Context of Thanksgiving in the United States.
• Opposite Effects of Low-Carbohydrate High-Fat Diet on Metabolism in Humans and Mice.

Caloric and Dietary Restriction

• Glucose Restriction in Saccharomyces cerevisiae Modulates the Phosphorylation Pattern of the 20S Proteasome and Increases Its Activity.
• Single Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Generates Sustained Improvement of Glycemic Control Compared with Sleeve Gastrectomy in the Diet-Induced Obese Rat Model.
• Recombinant-Methioninase-Producing Escherichia coli Instilled in the Microbiome Inhibits Triple-Negative Breast Cancer in an Orthotopic Cell-Line Mouse Model.

Exercise & Physical Activity

• Meta-Analysis: Effects of Exercise Interventions on Cognitive Functions in Healthy Populations.
• Systematic Review: Perspectives on Concurrent Strength and Endurance Training in Healthy Adult Females.
• Joint Associations of Device-Measured Physical Activity and Abdominal Obesity with Incident Cardiovascular Disease.
• RCT: Effect of High-Intensity Interval Training and Moderate-Intensity Continuous Training in People with Poststroke Gait Dysfunction.

Economics & Sociology

• Review: Obesity from a Sign of Being Rich to a Disease of the New Age.
• Do Differences in Sport Participation Contribute to Socioeconomic Health Inequalities? Evidence from the Lifelines Cohort Study on All-Cause Mortality, Diabetes and Obesity.

Epidemiology

• Association of Obesity with Cardiovascular Disease in the Absence of Traditional Risk Factors.
• Ideal Body Weight-Based Determination of Minimum Oral Calories Beneficial to Function and Survival in ALS.
• Estimating the Effects of Preventive and Weight-Management Interventions on the Prevalence of Childhood Obesity in England.
• COVID-19 Pandemic-Related Weight Gain in the Pediatric Population Declined After Restrictions Ended, Except Among Patients with Obesity.
• Obesity and Cardiac Conduction Block Disease in China.

Psychology & Neuroscience

• Diet-Induced Glial Insulin Resistance Impairs the Clearance of Neuronal Debris in Drosophila Brain.
• Meta-Analysis: Brain Dopamine Receptor System Is Not Altered in Obesity.
• Modulation of GABA Release by 5-HT1B Receptors: An Interplay with AMPA-Receptors and Voltage-Gated Ca2+ Channels.

Equity and Disparities

• Abstract: Community-Based Interventions to Address Obesity in the Context of Health Equity.
• Abstract: Evidence-Based Interventions for Cancer Equity, Clinic-Based Interventions to Promote Patient-Centered Care, and Weight Loss and Management.
• Spatiotemporal Change in Wealth-Based Inequalities in Overweight/Obesity Among Women of Reproductive Age in India, 2015–2021.

Ethics

• Editorial: The Genetics of Obesity: A New Narrative or the Same Old Story?

Stigma

• Female Advertising Models and Their BMI: How Does BMI Similarity Affect Perceived Product Quality?
• Weight Stigma Associated with Mental Health Concerns Among College Students.
• Moderation of Associations between Weight Discrimination and Diabetes Status by Psychosocial Factors.
• How are People with Obesity Managed in Primary Care? – Results of a Qualitative, Exploratory Study in Germany 2022.
• The Challenge of Weight Stigma for Women in the Preconception Period: Workshop Recommendations for Action from the 5th European Conference on Preconception Health and Care.

Policy Related

• Putting the Dietary Guidelines for Americans Into Action Through the National Strategy on Hunger, Nutrition, and Health.
• Food Retail Environments, Extreme Weather, and Their Overlap: Exploratory Analysis and Recommendations for U.S. Food Policy.
• Using Online Photovoice to Explore Food Decisions of Families on Low Income: Lessons Learnt During the COVID-19 Pandemic.
• Analysis of Public Perception of National Obesity Management Policy.

Intergenerational Effects

• Evaluating the Association between Caesarean Delivery and Weight Status in Early Childhood in a Japanese Birth Cohort Study.
• The Role of Adverse Childhood Experiences in Obesity Among Adolescents with Autism Spectrum Disorder.

Ecology, Evolution, & Energetics

• Metabolic Rates in Female Guinea Pigs During Different Reproductive Stages.
• Very-Low-Calorie Diets with High and Low Protein Content: Impact on Triiodothyronine, Energy Expenditure, and Nitrogen Balance.
• The Regulatory Role of MicroRNAs in Obesity and Obesity-Derived Ailments.

Methods

• Discretizing Continuous Variables in Nutrition and Obesity Research: A Practice That Needs to Be Cut Short.
• Effects of Different Obesity Evaluation Indexes on Long-Term Blood Pressure Variability in Adults.
• Editorial: Is There a Need for a Dedicated Pharmacokinetic Trial for a Drug in Populations with Obesity? A Drug Prioritization Decision Tree Framework.

Mathematical and Quantitative

• Abstract: Modeling of Lipolysis in the Human Body and the Methodology for Developing Technology of Supplements for Obesity Prevention Considering the Utilization of Food Industry By-Products.

Commentary

• Antiobesity Pharmacotherapy in Adults with Chronic Kidney Disease.
• Three Details Worth Knowing About the SELECT Study.
• Defining and Diagnosing Obesity in India: A Call for Advocacy and Action.
• Caught between Confronting Reality and Claiming Autonomy.
• How Does APOE Status Impact the Relationship between Obesity and Dementia Risk?
• A Call for Obesity Prevention Interventions for Young Children with Intellectual and Developmental Disabilities.
• Understanding the Relationship between Body Composition and Mortality Using Artificial Intelligence (AI).
• Obesity as a Neuroendocrine Disorder.

General

• An Interdisciplinary and Immersive Real-Time Learning Experience in Adolescent Nutrition Education Through Augmented Reality Integrated with Science, Technology, Engineering, and Mathematics.
• Sex Differences in Mouse Longevity and Responses to Geroprotective Drugs: Implications for Human Intervention.
• Vertically Inherited Microbiota and Environment-Modifying Behaviors Indirectly Shape the Exaggeration of Secondary Sexual Traits in the Gazelle Dung Beetle.
• Occupational Heat Stress Recommendation Compliance Attenuates Acute Kidney Injury Risk Compared to a Work-Rest Matched, Positive Control Scenario.
• The Significance of Hair: We Endow Hair with Psychological and Symbolic Meaning.
• Intra-Uterine Programming of Future Fertility.
• Disentangling the Dynamics of Energy Allocation to Develop a Proxy for Robustness of Fattening Pigs.
• Evaluating Tests for Cluster-Randomized Trials with Few Clusters Under Generalized Linear Mixed Models with Covariate Adjustment.

Video & Audio

• PCAST Advancing Nutrition Workshop Presentations.
• The Sugar Mind Trap: Obesity's Path to Neurodegeneration.
• SELECT Trial and Implications for Population Health.

Announcements

• A Great Model at Indiana University School of Public Health for Stimulating Grant Writing and Submissions.
• Registration Is Now OPEN for Our Advanced Therapies in Pediatric Obesity (ATPO) 2024 Conference. This Is a LIVE Virtual Conference Which Will Be Recorded.* Wednesday, February 21st-Friday, February 23rd 8 AM - 12 N CT Each Day.