Featured

• RCT: Cost-Effectiveness of Goal-Directed and Outcome-Based Financial Incentives for Weight Loss in Low-Income Populations.
• Regulatory T Cells Shield Muscle Mitochondria from Interferon-γ-Mediated Damage to Promote the Beneficial Effects of Exercise in Mice.
• Fructose: a modulator of intestinal barrier function and hepatic health?
• Assessing the Evolutionary Lability of Insulin Signalling in the Regulation of Nutritional Plasticity Across Traits and Species of Horned Dung Beetles.

Headline vs Study

• Headline: Obesity: Study Suggests Fructose Is the Key Cause of Weight Gain.
• Press Release: What Drives Obesity - Diets High in Fat? Carbohydrates? Actually, It’s Everything – and Fructose Is at the Center.
• Study: A Review Article Arguing a Fructose Survival Hypothesis.

Contrary or Null Findings

• "Pooled results from the random-effects model indicated that the GFD [Gluten Free Diet] has no significant effect on any of the factors of anthropometry, including weight …BMI …waist circumference …and body fat..."
• "Contrary to our predictions, higher BMI predicted less attentional priority for images of food and food logos."
• Meta-Analysis: Evidence of Post-Activation Performance Enhancement on Endurance Exercises.
• RCT: "No effect on vegetable intake was identified. According to sensitivity analyses, effects on fruit intake among the complete sample did not remain significant at 36 months..." in Evolution of fruit and vegetable intake among health promotion service participants in a Brazilian metropolis: 48-month follow-up.
• RCT: "In our study, HM macronutrients were overall not influenced by the NiPPeR intervention supplement taken preconceptionally and during pregnancy" in "A nutritional supplement taken during preconception and pregnancy influences human milk macronutrients in women with overweight/obesity and gestational diabetes mellitus." (pdf)
• RCT: Oral Magnesium Supplementation Does Not Affect Insulin Sensitivity in People with Insulin-Treated Type 2 Diabetes and a Low Serum Magnesium.
• RCT: "Pre-specified analysis per randomization found no effect of the intervention on the 2-year overall mean systolic and diastolic blood pressure (SBP, DBP) and any other outcomes" in Experience with 2 years’ intervention to progressively reduce salt supply to kitchens in elderly care facilities.
• RCT: Four Sessions of Repeated-Sprint Cycling Training with or Without Severe Hypoxia Do Not Modify Overground Running Sprint Force-Velocity Profile.

Basic

• Deficiency of Histone Variant MacroH2A1.1 Is Associated with Sexually Dimorphic Obesity in Mice.
• TRPV4 in Adipose Tissue Ameliorates Diet-Induced Obesity by Promoting White Adipocyte Browning.
• Transcriptional Repression of Beige Fat Innervation Via a YAP/TAZ-S100B Axis.
• Loss of Phospholipase PLAAT3 Causes a Mixed Lipodystrophic and Neurological Syndrome Due to Impaired PPARγ Signaling.
• Metabolic Consequences of Skeletal Muscle- and Liver-Specific BBSome Deficiency.

Scientific Rigor & Scholarly Dialogue

• Retraction: Kweichow Moutai Ameliorates Alcohol-Induced Liver Fibrosis in Mice by Targeting the NFκB Pathway.
• Letter to the Editor from Richmond et al: “Sleep Duration and Visceral Adipose Tissue: Linear and Nonlinear Mendelian Randomization Analyses”.
• Visual Cues and Food Intake: A Preregistered Replication of Wansink et al. (2005).
• Retraction: The Relationship between the Mechanism of Sarcopenia and Exercise Based on Data Mining.

Clinical

• Lower Quality of Life in ICU Survivors with Obesity: A Multicenter Cohort Study.
• RCT: Effects of Energy Loads on Energy and Nutrient Absorption Rates and Gut Microbiome in Humans.
• Adherence to a Healthy Lifestyle, Genetic Susceptibility to Abdominal Obesity, Cardiometabolic Risk Markers, and Risk of Coronary Heart Disease.
• Meta-Analysis: Effects of Bifidobacterium Probiotic Supplementation on Blood Glucose: Preclinical Animal Models and Clinical Evidence.

Children and Adolescents

• Pediatric Obesity Prevalence in the U.S. Military Health System, Fiscal Years 2012-2018.
•  Narrative Review: Evidence for Primary Prevention of Overweight and Obesity in Healthy Weight Children and Adolescents.
• Chapter: Dietary Interventions for Pediatric Obesity.
• Physical Fitness Among Children with Diverse Weight Status During and After the COVID-19 Pandemic.
• Editorial: Maternal Dietary and Lifestyle Patterns with Pregnancy, Birth, and Child Health Outcomes.

Surgery

• Obesity and Its Comorbidities, Current Treatment Options and Future Perspectives: Challenging Bariatric Surgery?
• Meta-Analysis: Bariatric Surgery Reduces Colorectal Cancer Incidence in Individuals with Obesity.
• Narrative Review: Impact of Bariatric Surgery on Patients' Satisfaction and Quality of Life.
• A Novel Pathogenic Variant in MRAP2 in a Patient with Obesity with Successful Outcome of Bariatric Surgery.
• The Impact of BMI on Adverse Outcomes Associated with Panniculectomy: A Multimodal Analysis.
• What Matters to Adolescents with Obesity, and Their Caregivers, When Considering Bariatric Surgery or Weight Loss Devices? A Qualitative Evidence Synthesis.

Drugs

• “FDA Approves New Medication [Tirzepatide] for Chronic Weight Management.”
• RCT: Acute Effect of Different Doses of Caffeinated Chewing Gum on Exercise Performance in Caffeine-Habituated Male Soccer Players.
• Weight Change in a National Cohort of U.S. Military Veterans Engaged in Medication Treatment for Opioid Use Disorder.
• Use and Continuity of Weight-Modifying Medications Among Adults with Diabetes and Overweight/Obesity: US Population Study.

Food & Diet

• Meta-Analysis: The Relationship between Alcohol Consumption, BMI, and Type 2 Diabetes.
• Meta-Analysis: Substitution of Sugar-Sweetened Beverages with Non-Caloric Alternatives and Weight Change.
• Systematic Review: Who Consumes Ultra-Processed Food? A Systematic Review of Sociodemographic Determinants of Ultra-Processed Food Consumption from Nationally Representative Samples.
• Meta-Analysis: Reference Range for Circulating Ionized Magnesium Concentrations in Adult Populations.

Caloric and Dietary Restriction

• Perspective: Does Dietary Nitrate Boost the Effects of Caloric Restriction on Brain Health? Potential Physiological Mechanisms and Implications for Future Research.
• Prenatal Caloric Restriction Adjusts the Energy Homeostasis and Behavior in Response to Acute and Chronic Variations in Food Availability in Adulthood.

Exercise & Physical Activity

• Reported Barriers to Physical Activity and the Role of Built Environment Among Youth with Overweight and Obesity Attending a Canadian Pediatric Weight Management Clinic.
• Parental Perceptions of Physical Activity and Risk of Disease Associated with Sedentary Behaviours in Infants and Toddlers.

Economics & Sociology

• Multilevel Prenatal Socioeconomic Predictors of Mexican American Children’s Cardiometabolic Health in Preschool and School Age.
• Relationship of Living and Eating Arrangements to Mental Distress Among Older Korean Immigrants: Gender Difference in the Mediating Role of Loneliness.
• Systematic Review: Economic Costs of Obesity.

Epidemiology

• Mendelian Randomization: "Age-related hearing impairment may reduce body mass index."
• Age and Sex Differences in the Association between Neighborhood Socioeconomic Environment and Incident Diabetes: Results from the Diabetes Location, Environmental Attributes and Disparities (LEAD) Network.
• Increased Body Weight and Central Adiposity Markers are Positively Associated with the 20-Year Incidence of Cardiovascular Disease: The ATTICA Epidemiological Study (2002-2022).
• Review: Epidemiology of Obesity Among People with HIV.
• Abstract:  Sociodemographic Measures and Disparities in Obesity in US Rural vs Nonrural Counties, 2004-2019.
• Trends in Weight Change Patterns Across Life Course Among US Adults, 1988–2018: Population-Based Study.
• Comparative Analysis of Lifestyle Behaviors and Dietary Intake Among Individuals With and Without Obesity Following Bariatric Surgery: A Secondary Data Analysis from 2020 to 2022.
• Impact of the Immune Profiles of Hypertensive Patients With and Without Obesity on COVID-19 Severity.

Psychology & Neuroscience

• Neural Adaption in Midbrain GABAergic Cells Contributes to High-Fat Diet-Induced Obesity.
• Behavioral Treatment and Psychological Complications of Pediatric Obesity.
• Predicting High-Risk Periods for Weight Regain Following Initial Weight Loss.

Equity and Disparities

• Meta-Analysis: Sex-Specific Obesity and Cardiometabolic Disease Risks in Low- and Middle-Income Countries.
• The Impact of COVID-19 on BMI Among Hispanic Children Accessing a Primary Care Clinic in Central Texas: An Epidemic Amidst a Pandemic.

Stigma

• Systematic Review: Psychosocial Consequences of Weight Screening of School-Age Children.
• From Labels to Humiliation: Generation of Discrimination and Resilience in the Obese Population.
• The Role of Body Image and Refusal to Be Weighed: Implications for Primary Healthcare.
• Weight Stigma Is Associated with BMI Among College Students in Taiwan: The Mediated Role of Internalized Weight Stigma.

Policy Related

• The Need to Promote Sleep Health in Public Health Agendas Across the Globe.
• How Indigenous Knowledge May Shape the Future of U.S. Policy.
• Living with Obesity in Ireland – Determinants, Policy, and Future Perspectives.
• Lessons for Strengthening Policymaking for Obesity and Diet-Related Noncommunicable Disease Prevention: A Narrative Synthesis of Policy Literature from the Western Pacific Region.
• State Supplemental Nutrition Assistance Program Policies and Substance Use Rates.

Intergenerational Effects

• Placental Pathologic Features in Obesity.
• Maternal BMI and Smoking as Mediators in the Maternal Education – Offspring Asthma Association in a Register-Based Cohort.

Ecology, Evolution, & Energetics

• Metabolic Syndrome Accelerates Epigenetic Ageing in Older Adults: Findings from The Irish Longitudinal Study on Ageing (TILDA).
• Lifestyle Interventions to Delay Senescence.

Methods

• Accuracy of Heart-Rate-Recovery Parameters Assessed from a Wrist-Worn Photoplethysmography Monitor.
• Improving Transportability of RCT Inference Using Robust Prediction Methods.

Commentary

• A Call to the European Congress on Obesity: It’s Time to Remove Corporate Sponsorship.
• Lifestyle-Based Obesity Care.
• The Long Goodbye to Brominated Vegetable Oil.
• Paying a Heavy Price: Costs of Care for People with Severe Obesity in Nursing Homes.
• Outlook for the Future of Food in America.
• Prize Winner's Research Reveals Neural Cells in the Gut That Aid Digestion.
• How Pharmaceutical Companies Misappropriate Fat Acceptance.
• How to Measure the Calories in a Candy Bar—With Physics!

General

• Are Probiotics Actually Beneficial?
• A Vaping Inquisition.
• Two Questions, Hundreds of Scientists, No Easy Answers: How Small Differences in Data Analysis Make Huge Differences in Results.
• Testing the Effects of Kinship, Reciprocity and Dominance on Prosocial Food Provisioning in Azure-Winged Magpies (Cyanopica cyana), Carrion Crows (Corvus corone) and Common Ravens (C. corax).
• Genetic Conflict and the Origin of Multigene Families: Implications for Sex Chromosome Evolution.
• Understanding Organisms Using Ecological Observatory Networks.
• Dysfunction of Mitochondria Drives the Exhaustion of T Cells, Study Shows.
• Unintended Effects of Preferential Tax Assessment on Farmland Protection: Evidence from Utah's Farmland Assessment Act.
• The Impact of Subjective Social Class on Subjective Well-Being: Examining the Mediating Roles of Perceived Scarcity and Sense of Control.
• The “Free Lunches” Index for Assessing Academics: A Not Entirely Serious Proposal.

Announcements

• WEBINAR: Nov 28 - More Than What You Eat: The Regulation of Metabolic Health and Aging by Diet Composition and Activity.
• Indiana University to Invest $250 Million in Bioscience and Technology Initiatives.
• Book Review: Rethinking Diabetes - What Science Reveals About Diet, Insulin, and Successful Treatments by Gary Taubes.