11/07/25
Featured
- Diagnostic Ultrasound Irradiation Combined with Microbubbles to Modulate Carotid Body Activity for the Treatment of Obesity-Related Hypertension in Rabbits.
- Weightlifting Outperforms Voluntary Wheel Running for Improving Adiposity and Insulin Sensitivity in Obese Mice.
- Targeting the MTOR-Mitochondrial Function Axis: Calcitriol Attenuates Sarcopenic Obesity with Lipid Dysregulation Etiology [in Mice].
Headline vs Study
- Headline: What? I Can't Have Bacon in My Full English Breakfast Now?
- Headline: Bacon and Ham Linked to Cancer Risk - Here's What Scientists Want You to Know.
- Letter: Coalition Against Nitrites Call for Action on Nitrite-Cured Meats in Reference to Ten Year Old WHO IARC Report. No New Evidence Presented; Nothing Preventing Your Full English Breakfast.
Contrary or Null Findings
- RCT: "None of the [physical activity promotion and micronutrient supplementation] interventions significantly improved daily PA…[and] the PA + MMNS arm increased body fat percentage…".
- RCT: "After controlling for age, BMI, sequence and period, there were no condition*time interactions for IL-6 (primary endpoint)..." [in] "Inflammatory Cytokine Responses to Six Weeks of Increased Dairy Intake in Individuals with Overweight and Obesity".
- RCT: "Despite lower adherence in the high-dose group, adherence showed little association with clinical outcomes. These results suggest that high adherence to high-dose exercise may not be necessary for short-term benefit..." in knee osteoarthritis.
- RCT: No Significant Impact of Nutrition Counselling Via Online Application on Nutrient Intake Among Thai Older Adults During COVID-19.
- RCT: "Metformin did not reduce [low risk prostate cancer] progression in men with low-risk PCa on AS....In prespecified subgroup analysis, metformin was associated with increased pathologic progression among obese patients (BMI ≥ 30; HR, 2.36 [95% CI, 1.21 to 4.59]; P = .0092)."
- RCT: Metformin "blunts exercise training-mediated increases in vascular insulin sensitivity at the levels of conduit arteries and capillaries..."
- RCT: No Effect of "Disclosure of Genotype Information to Reduce Caffeine Intake in Slow Metabolizers: Findings from RCT on Personalized Dietary Interventions.”
- RCT: No significant "effects of digital health intervention (DHI) or/and personalized healthy breakfast guidance (PHBG) on ...body composition of young adults in Tianjin..."
Basic
- Short-Term Exposure to Lauric Acid Promotes Adipose Tissue Lipolysis and Reduces Leptin Expression Via a PPARγ-Dependent Mechanism.
- Leucine Inhibits Degradation of Outer Mitochondrial Membrane Proteins to Adapt Mitochondrial Respiration.
- Review: Tracing the Path from Obesity to Diabetes: How S-Allyl Cysteine Shapes Metabolic Health.
- Preprint: Mitochondrial Uncoupler BAM15 Improves Skeletal Muscle Function and Mitochondrial Respiration in Sarcopenia.
Scientific Rigor & Scholarly Dialogue
- PubPeer Comments On: Protective Effect of Vitamin D Supplementation on COVID-19-Related Intensive Care Hospitalization and Mortality: Definitive Evidence from Meta-Analysis and Trial Sequential Analysis.
- Retraction: Argano et al. Protective Effect of Vitamin D Supplementation on COVID-19-Related Intensive Care Hospitalization and Mortality: Definitive Evidence from Meta-Analysis and Trial Sequential Analysis. Pharmaceuticals 2023, 16, 130.
- Meta-Analysis of RCTs: "Acute exercise significantly improved executive function (moderate evidence, 9 studies, 330 participants, g = 0.33, small effect, 95% CI, 0.07-0.59, P = .01, I2 = 26.77%). However, this was only for high risk of bias/crossover studies."
- Retraction: Sesame Oil and Vitamin E Co-Administration May Improve Cardiometabolic Risk Factors in Patients with Metabolic Syndrome: A Randomized Clinical Trial.
Clinical
- Combining Medications with Bariatric Surgery to Treat Obesity.
- Long-Term Administration of Liraglutide for Weight Management in Pediatric Patients Under 18 Years: Evidence from 7 RCTs.
- Exploring the Relationship between Obesity, Weight Loss and Health-Related Quality of Life: An Updated Systematic Review of Reviews.
- To What Extent Do Clinical Practice Guidelines for Chronic Diseases Embrace Current Obesity Management Guidance? A Qualitative Content Analysis.
Children and Adolescents
- Jumping Hurdles: A Grounded Theory Study of Factors Influencing School Nurses' Role in Pediatric Obesity Prevention in Saudi Arabia.
- Tiered School-Family-Clinic Intervention for Childhood Obesity Prevention in China.
- A Prospective Cohort Analysis from Germany Shows Transition Into Adulthood Is an Underestimated Vulnerable Period for Children with Overweight/Obesity.
Surgery
- Abstract: The Impact of Bariatric Surgery on Pancreatic Adenocarcinoma and Exocrine Pancreatic Insufficiency Risk in Patients with Chronic Pancreatitis and Morbid Obesity: A National Readmission Database Analysis.
- ANGPTL8 Is Upregulated in Subcutaneous Adipose Tissue at Early Term After Bariatric Surgery in Patients Living with Obesity.
- Metabolic Bariatric Surgery in Older Patients: Is It Worth It? BARI-10-POL Study.
- Retrospective Study: Bariatric Surgery: Pre-Operative Comorbidities, Postoperative Results, and Complications.
Drugs
- Commentary: Tirzepatide and the NHS: Are We Creating a Two-Tier Obesity Treatment System?
- Thermogenic Targets for Obesity Management in the Era of Incretin-Based Therapies.
- “The New DNP”: Discussion of the Experimental ‘Fat Burner’ BAM15 on Bodybuilding Forums and YouTube.
Food & Diet
- Ketogenic Diet Modulates Gut Microbiota–Brain Metabolite Axis in a Sex- and Genotype-Specific Manner in APOE4 Mice.
- Soy Protein Outperforms Whey Protein in Ameliorating Insulin Resistance but Not Obesity in High-Fat Diet-Induced Obese Mice.
- High Consumption of Ultra-Processed Foods Is Associated with Genome-Wide DNA Methylation Differences in Women: A Pilot Study.
Caloric and Dietary Restriction
- Comparison of an Energy-Reduced Mediterranean Diet and Physical Activity Versus an Ad Libitum Mediterranean Diet in the Prevention of Type 2 Diabetes: A Secondary Analysis of a RCT.
- Intended Isocaloric Time-Restricted Eating Shifts Circadian Clocks but Does Not Improve Cardiometabolic Health in Women with Overweight.
- Semaglutide Versus Caloric Restriction-Induced Weight Loss: Insights Into Effects on Skeletal Muscle Mass and Function.
Exercise & Physical Activity
- Sex Differences in Upper-Body Strength, Lean Mass, and Bone Density Across the Adult Lifespan: Insights Into Musculoskeletal Aging and Strength Preservation.
- Effects of 8-Week High-Intensity Interval Training Intervention Regulating the SIRT1/PGC1α Pathway on Hippocampal Neuron Injury and Cognitive Impairment in Obese Rats.
- Impact of an 8-Week High-Intensity Bodyweight Interval Training on Body Composition and Blood Lipid Metabolism in Young Women with Overweight.
Economics & Sociology
- Impact of Sugar-Sweetened Beverages Tax on Obesity and Obesity-Related Health Conditions: Evidence from Washington State’s Soft Drink Syrup Tax.
- Incident Cases and Healthcare Costs of Non-Communicable Diseases Attributable to Industrialized and Total Sugar Sweetened Beverage Intake in Mexico.
- Factors Shaping Dietary Choices of Black African Immigrant Women with Overweight and Obesity from West Africa Living in the UK.
Epidemiology
- Rising Trends in Obesity and Heart Failure: Related Mortality in the United States, 1999-2024.
- Prevalence of Overweight, Obesity and Underweight and Associated Factors in a Three-Generation Population-Based Study in a Large Russian Region.
- Long-Term Waist Circumference and Diabetes Risk in Premenopausal Women: Role of Shared Risk Factors.
Psychology & Neuroscience
- The Influence of Referral, Initial Assessment, and Logistical Factors on Dropout at an Adult Weight Management Service: A Semi Structured Interview Study.
- Weight Loss After Obesity Disrupts Cognitive Flexibility Through Reinforcement Learning Strategies.
- Do We Just Need to Eat Less Often? An Update on the Role of Eating Frequency and Intermittent Fasting for Obesity Prevention and Management.
Differential Population Circumstances, Exposures, Outcomes, and Effects
- Disparities and Trends in Pulmonary Embolism Mortality with and Without Obesity: A Nationwide U.S. Analysis.
- Abstract: Demographic and Regional Disparities in GLP-1 Receptor Agonist Clinical Trials for Weight Loss: A Comparative Meta-Analysis of US and International RCTs.
- Anthropometric Indices of Obesity and Their Relationships with Diabetes Risk by Race and Ethnicity Among Postmenopausal Women.
Ethics
- Big Data, Machine Learning, and Personalization in Health Systems: Ethical Issues and Emerging Trade-Offs.
- Report: Science in the Age of AI: How Artificial Intelligence Is Changing the Nature and Method of Scientific Research.
Stigma
- Family-Based Weight Stigma and Psychological Well-Being of Adolescents: A Longitudinal Analysis of Recent Vs. Cumulative Exposure.
- Weight Stigma and Implicit Bias in Healthcare: Investigating the Impact of Women's Body Size on Continuity of Care and Communication About Sexual and Reproductive Health.
- Understanding Overweight and Obesity: Contemporary Evidence-Based Approaches to Delivering Person-Centred Nursing Care.
Policy Related
- RCT: Nutrition Info and Other Front-Of-Package Labels and Simulated Food and Beverage Purchases.
- The Undernourished Curriculum: What Happened to Nutritional Education in the Medical Curriculum?
- Examining Effective Translation and Implementation Methods for Equitable Access and Scaling of Nutrition Programs - A Report from the “Biomarkers of Nutrition for Development: Knowledge Indicating Dietary Sufficiency (BOND-KIDS)” Project Working Group 4.
Intergenerational Effects
- Discovery of Obesity Genes Through Cross-Ancestry Analysis.
- Relationship between Maternal Obesity, Birth Weight, and Fetal Adiponectin/Leptin Ratio: A Potential Early Biomarker of Cardiometabolic Risk.
- Epigenetic Mediation May Explain Intergenerational Associations between Maternal Obesogenic Lifestyle and Children’s Birth Weight: Findings from the NorthPop Prospective Birth Cohort.
Ecology, Evolution, & Energetics
- Lipolysis Gone Rogue: The HSL Connection in Feeding Cancer.
- Is the vLamax for Glycolysis What the VO2max Is for Oxidative Phosphorylation?
- Shifts in Salamander Body Size Associated with 60 Years of Climate Change.
Methods
- Performance Evaluation of 3 Large Language Models for Nutritional Content Estimation from Food Images.
- ToF Based Wearable Sensing for Passive Food Intake Monitoring.
Commentary
- Anti-Obesity Medications Set to Explode Entering 2026.
- Podcast: Strength Training and Myokines: Unlocking Exercise as Medicine.
- Advancing Policy, Systems and Environmental Change Research to Reverse Upward Trends in Obesity Prevalence - A New Call to Action.
- Should Young People Take Creatine?
- Emerging Challenges in the Epidemic of Diabetes and Obesity: The Need for Evidence-Based and Policy-Oriented Strategies.
- Seriously, Can Use of GLP-1s Lower Obesity Prevalence?
- Podcast: Weight Bias, Diabetes Distress & Trauma Informed Care – Dr. Robyn Pashby.
- Today’s ‘Skinny Influencers’ are Selling Something More Mind-Bending Than Weight Loss.
General
- Novel Approach Restores Sperm Production in Mouse Model of Infertility.
- RCT: Sensory Trial of Camel Milk Powder Among Pastoralist Communities of the Somali Region, Ethiopia.
- Meta-Analysis of RCTs: "Overall, inositol may offer modest cardiometabolic benefits, with moderate-to-high certainty for improvements in insulin resistance and lipid profiles. However, existing studies show a high risk of bias and low certainty of evidence, particularly for anthropometric outcomes, creating cautious interpretation."
- RCT: "An 8-week pickleball program significantly improved balance, gait, and social engagement in older adult women."
- RCT: "For patients with degenerative meniscal tear and knee pain, the addition of physical therapy or text messages to encourage adherence to home exercises was not superior in reducing pain to a home-exercise program alone."
- Why Psychopathology Research Should Avoid Studying One Mental Disorder at a Time: An Intergenerational and Developmental Evidence Base for Understanding “p”.
- Fruit Flies Offer New Insights Into How Human Alzheimer’s Disease Risk Genes Affect the Brain.
- Perceptions of Food and Alcohol Disturbance: A Vignette Experiment Examining the Role of Gender and Calorie Restriction Motive.
- Saying ‘No’ with Confidence: Statistical Approaches to Test for the Absence of an Effect.
- Obesity Rates by Country 2025.
Video & Audio
Announcements
- 125 Years of Discovery, Care and Impact: The Legacy and Future of Baylor College of Medicine.
- Call for Abstracts: American Society for Nutrition's NUTRITION 2026.
- David B. Allison, PhD (Baylor College of Medicine), Lauren Hunt, PhD, RN, FNP (UCSF), and Arlan Richardson, PhD (University of Oklahoma Health Sciences) to Receive AFAR Annual Scientific Awards of Distinction.