Featured

• "Highly processed foods, from pizza to bread, are said to be seriously bad for your health. Here is a digestible guide to what the evidence says, to help you make sense of the conflicting claims."
• BMI Trajectories and Mortality Risk in Japan Using a Population-Based Prospective Cohort Study.
• Untargeted Metabolomic Analysis Investigating Links between Unprocessed Red Meat Intake and Markers of Inflammation.
• Evaluation of Food Security Status, Psychological Well-Being, and Stress on BMI and Diet-Related Behaviors Among a Sample of College Students.

Headline vs Study

• Headline A: One Extra Cup of Coffee a Day May Help Avoid Weight Gain. Here's Why.
• Study A: An Increase in Self-Reported Coffee Intake Was Inversely Associated with Weight Gain, Depending on Whether Participants Self-Reported Adding Sugar or Creamer. Causation Not Established.
• Headline B: Adding Sugar to Coffee, Tea May Not Significantly Impact Health.
• Study B: Self-Reported Use of Sugar in Self-Reported Tea and/or Coffee Consumption Was Not Significantly Associated with Increased Risk of Mortality or Incident Diabetes. Causation Not Established.

Contrary or Null Findings

• Systematic Review: "We need to acknowledge that we do not have sufficient knowledge about how to prevent children with a healthy weight from developing overweight."
• Meta-Analysis: Exercise Training Improves Brachial Artery Endothelial Function, but Does Not Alter Inflammatory Biomarkers in Patients with Peripheral Artery Disease.
• Functional Knockout of the TRPV1 Channel Has No Effect on the Exercise Pressor Reflex in Rats.
• No Evidence for Direct Thermal Carryover Effects on Starvation Tolerance in the Obligate Blood-Feeder, Glossina morsitans.
• RCT: "After 3 months (n = 81), no difference in weight, BMI, waist circumference, blood pressure, or biomarkers were observed between the groups" in evaluating probiotic efficacy on weight loss in adults with overweight.
• RCT: No Differential "Effects of 12 Weeks of Family and Individual Multi-Disciplinary Intervention in Overweight and Obese Adolescents under Cardiometabolic Risk Parameters."
• RCT: "Contrary to our postulated hypothesis, we did not observe significant differences between the study groups in glucose tolerance and HbA1c" in Pilot Study of the Food Order Behavioral Intervention in Prediabetes.

Basic

• Changes in Brown Adipose Tissue Induced by Resveratrol and Its Analogue Pterostilbene in Rats Fed with a High-Fat High-Fructose Diet.
• CTRP13 Ablation Improves Systemic Glucose and Lipid Metabolism.
• Deletion of Adipocyte NOS3 Potentiates High-Fat Diet-Induced Hypertension and Vascular Remodeling Via Chemerin.
• Dual Roles of Myocardial Mitochondrial AKT on Diabetic Cardiomyopathy and Whole Body Metabolism.
• High-Fat Diet Impairs Glucose Homeostasis by Increased P16 Beta-Cell Expression and Alters Glucose Homeostasis of the Progeny in a Parental-Sex Dependent Manner.
• Adipose Tissue as a Cause of Endocrine Dysfunction.

Scientific Rigor & Scholarly Dialogue

• Specks and Logs, Bias and Conflicts.
• Retraction Watch: “History Repeats Itself: Diabetes Researcher Gets Four Expressions of Concern in Journal He Once Sued."

Clinical

• Obesity Dysregulates the Pulmonary Antiviral Immune Response.
• Bone Marrow Adiposity Alterations in Type 2 Diabetes are Sex-Specific and Associated with Serum Lipid Levels.
• Impact of Metformin and Dysosmobacter Welbionis on Diet-Induced Obesity and Diabetes: From Clinical Observation to Preclinical Intervention.
• Meta-Analysis: Is Binge Eating Associated with Poor Weight Loss Outcomes in People with a High Body Weight?
• Protocol: Effects of Pharmacist-Led Interventions on Glycaemic Control, Adherence, Disease Management and Health-Related Quality of Life in Patients with Type 2 Diabetes.
• RCT: Effect of the Smartphone Application on Caesarean Section in Women with Overweight and Obesity.
• Diabetes Complications Worsen Prognosis for Colorectal Cancer Patients.
• Adiponectin as a Key Player in Obesity-Driven Cancers.

Children and Adolescents

• Next Generation, Modifiable Cardiometabolic Biomarkers: Mitochondrial Adaptation and Metabolic Resilience.
• Estimating the Effects of Preventive and Weight-Management Interventions on the Prevalence of Childhood Obesity.
• Atherosclerosis from Newborn to Adult—Epidemiology, Pathological Aspects, and Risk Factors.
• MASLD vs. NAFLD: A Better Definition for Children with Obesity at Higher Risk of Kidney Damage.
• Circulating Extracellular Vesicles are Associated with Pathophysiological Condition Including Metabolic Syndrome-Related Dysmetabolism in Children and Adolescents with Obesity.
• Changes in Leukocyte Telomere Length Among Children with Obesity Participating in a Behavioural Weight Control Program.
• Systematic Review: Human Milk Bioactive Components and Child Growth and Body Composition in the First 2 Years.
• Ultra-Processed Foods and the Nutritional Transition Among Infants and Young Children.

Surgery

• Safety and Efficacy of Bariatric Surgery Versus Glucagon-Like Peptide-1 Analogue.
• Advanced Lipoproteins and Lipidomic Profile in Plasma Determined by Nuclear Magnetic Resonance Before and After Bariatric Surgery.
• Bariatric Evaluation Through AI.
• Positive Predictive Value for Multitarget Stool DNA After Bariatric and Metabolic Surgery.

Drugs

• Viking Therapeutics Announces Completion of Enrollment in Phase 2 Trial of Dual GLP-1/GIP Receptor Agonist VK2735 in Patients with Obesity.
• Meta-Analysis: Tirzepatide-Induced Gastrointestinal Manifestations.

Food & Diet

• Healthy Food and Determinants of Food Choice on Online Food Delivery Applications.
• The Underlying Role of Food Guilt in Adolescent Food Choice: A Potential Conceptual Model for Adolescent Food Choice Negotiations Under Circumstances of Conscious Internal Conflict.
• Termites as Human Foods.
• Moving Towards Healthier Eating Habits | Why Low- and No-Calorie Sweeteners Play a Critical Role. (pdf)
• RCT: Anti-Obesity Effect of Neoagaro-Oligosaccharides for Subjects with Overweight or Obesity.
• RCT: Effect of Time-Restricted Eating on Weight Loss in Adults with Type 2 Diabetes.
• Perspective: Carbohydrate Confusion and Dietary Patterns: Unintended Public Health Consequences of “Food Swapping”.
• The Association between Alcohol Intake and Obesity in a Sample of the Irish Adult Population.
• Scoping Review: Benefits and Side Effects of Protein Supplementation and Exercise in Sarcopenic Obesity.
• 10 Best High-Protein Snacks, According to Dietitians.

Caloric and Dietary Restriction

• A Cluster of X-Linked MiRNAs are De-Repressed with Age in Mouse Liver and Target Growth Hormone Signaling.
• Changes in the Prevalence of U.S. Adults Using Diet, Exercise, Pharmaceuticals and Diet Products for Weight Loss from 1999–2018.

Exercise & Physical Activity

• Device-Measured Physical Activity, Sedentary Time, and Risk of All-Cause Mortality: An Individual Participant Data Analysis of Four Prospective Cohort Studies.
• Associations Among Metabolic Health, Weight Status, and Various Physical Fitness Components in Japanese Adolescents.
• Impact of Physical Fitness and Exercise Training on Subcutaneous Adipose Tissue Beiging Markers in Humans with and Without Diabetes and a High-Fat Diet-Fed Mouse Model.
• The Role of Cardiopulmonary Fitness in Weight Loss.

Economics & Sociology

• "Differences in Body Weight According to Skin Color and Sex in Mexican Adults."
• ‘If You’re Serious About Losing Weight, Why are You Drinking All Those Cokes?’: A Critical Discourse Analysis of Interviews on Sugar-Sweetened Beverages Amongst Residents of a Middle to Upper Class Neighborhood in Winnipeg, Manitoba.
• Socioeconomic Factors Associated with Poor Medication Adherence in Patients with Type 2 Diabetes.

Epidemiology

• Gestational Weight Change in a Diverse Pregnancy Cohort and Mortality over 50 Years.
• Effects of Prepregnancy Dietary Patterns on Infant Birth Weight.
• Serum 25-Hydroxyvitamin D, Type 2 Diabetes, and Liver-Related Outcomes.
• The Triglyceride-Glucose Index Is a Predictor for Cardiovascular and All-Cause Mortality in CVD Patients with Diabetes or Pre-Diabetes.

Psychology & Neuroscience

• RCT: Effects of Zinc Supplementation on Inflammatory and Cognitive Parameters in Middle-Aged Women with Overweight or Obesity.
• Maternal DHA Intake in Mice Increased DHA Metabolites in the Pup Brain and Ameliorated MeHg-Induced Behavioral Disorder.

Equity and Disparities

• Narrative Review: Clinic-Community Food Provision Interventions Aimed at Improving Diabetes Outcomes Among Food-Insecure Adults: Examining the Role of Nutrition Education.
• Examining Neighbourhood-Level Disparities in Black, Latina/o, Asian, and White Physical Health, Mental Health, Chronic Conditions, and Social Disadvantage in California.
• Clinical Performance and Health Equity Implications of the American Diabetes Association's 2023 Screening Recommendation for Prediabetes and Diabetes.
• Building Bridges with School Boards-An Understudied Seat of Health Equity.

Ethics

• "How the Use of BMI Fetishizes White Embodiment and Racializes Fat Phobia."

Stigma

• RCT: The Effects of an Acute Weight Stigma Exposure on Cardiovascular Reactivity Among Women with Obesity and Hypertension.
• Weight Stigma Is a Predictor of Disordered Eating in Brazilian College Students During the COVID-19 Pandemic: A 16-Month Cohort Follow-Up.

Policy Related

• Food and Power in Protracted Crisis: How Systems and Institutions Influence Livelihoods, Food Security, and Nutrition.
• Can Government Investment in Food Pantries Decrease Food Insecurity?
• Food Justice: Turning Private Choices Into Public Issues.
• Comparing Product Healthiness According to the Health Star Rating and the NOVA Classification System and Implications for Food Labelling Systems: An Analysis of 25 486 Products in Australia.
• Society for Nutrition Education and Behavior Bi-Weekly Policy Update.
• Commentary: The Pitfalls of Ascribing Moral Agency to Corporations: Public Obligation and Political and Social Contexts in the Commercial Determinants of Health.

Intergenerational Effects

• Intergenerational Hyperglycemia Impairs Mitochondrial Function and Follicular Development and Causes Oxidative Stress in Rat Ovaries Independent of the Consumption of a High-Fat Diet.
• Paternal Obesity Induced by High-Fat Diet Impairs the Metabolic and Reproductive Health of Progeny in Rats.
• Supporting the Management of Gestational Diabetes Mellitus with Comprehensive Self-Tracking: Mixed Methods Study of Wearable Sensors.
• Continuous Glucose Monitoring Metrics in High-Risk Pregnant Women with Type 2 Diabetes.
• Hypoglycemia and Associated Comorbidities Among Newborns of Mothers with Diabetes in an Academic Tertiary Care Center.
• AI-Enhanced Analysis Reveals Impact of Maternal Diabetes on Subcutaneous Fat Mass in Fetuses Without Growth Alterations.
• Role of Oxidative Stress and Inflammation in Gestational Diabetes Mellitus.

Ecology, Evolution, & Energetics

• Mitochondrial Reactive Oxygen Species, Insulin Resistance, and Nrf2-Mediated Oxidative Stress Response-Toward an Actionable Strategy for Anti-Aging.
• Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice.

Methods

• Exploring Estrogen’s Role in Metabolism and the Use of 13C-Labeled Nutrients for Advanced Animal Physiology and Nutrition Research.
• Epicardial Adipose Tissue, Metabolic Disorders, and Cardiovascular Diseases: Recent Advances Classified by Research Methodologies.
• Comment: The Value of Ethnographic Studies for Making Inferences About the Nature of the Human Paleolithic Diet.

Commentary

• UAB Researchers Link College Student Health with Food Security.
• Red Meat May Not Cause Harmful Inflammation After All.
• How the Brain Protects Itself from Blood-Borne Threats.
• Is a Spoonful of Sugar in Coffee or Tea No Problem?
• Webinar: Solving Sodium – Insights, Science & Strategies to Help You Navigate the Salt Space.
• Speculation About Ripples from Effective Obesity Treatment.
• Special Episode: Peter Answers Questions on Longevity, Supplements, Protein, Fasting, ApoB, Statins, and More.
• Commentary: Renaming Obesity Won’t Fix Weight Stigma Overnight.

General

• "Bacteria use population heterogeneity, the presence of more than one phenotypic variant in a clonal population, to endure diverse environmental challenges - a 'bet-hedging' strategy."
• Editorial: The Role of Medicinal Plants and Natural Products in Modulating Oxidative Stress and Inflammatory Related Disorders, Volume II.
• Editorial: Antioxidant and Neuroprotective Potential of Alternative and Complementary Therapeutic Approaches Against Alzheimer’s Disease.
• A Luminous Fast Radio Burst That Probes the Universe at Redshift 1.
• Xanax’s Efficacy Questioned.
• Patterns of Enrichment and Acceleration in Evolutionary Rates of Promoters Suggest a Role of Regulatory Regions in Cetacean Gigantism,
• Survey on the Inclusion of Tobacco Prevention/ Cessation, Nutrition/Diet, and Exercise Physiology/ Fitness Education in Medical School Curricula. (pdf)
• Topoisomerase 1 Activity Is Reduced in Response to Thermal Stress in Fruit Flies and in Human HeLa Cells.
• Longevity May Be Associated with Olfactory Perception of Harmful Substances.
• Is Testosterone Replacement Therapy Both Safe and Effective in Men with Higher Cardiovascular Risk Factors?

Video & Audio

• Podcast: Fat Liberation and Weight Discrimination.

Announcements

• USDA Appoints New Members to Food Safety Advisory Committee.
• Webinar: Control of Muscle Glucose Uptake in Vivo: Thinking Outside the Myocyte Thursday, November 9, 2023 11:00 Am ET.
• Webinar: Processed Foods: Can They Be Right for Your Health or Are They Better Left on the Store Shelf?