Featured

• Meta-analyses of human gut microbes: although subjects can be classified as lean or obese within individual studies, signatures of obesity are not consistent across studies.
• A simple algorithm allows for more realistic predictions of intervention effects in free-living populations by accounting for the compensation that occurs.
• Researchers retract study supporting diet pills promoted by Dr. Oz.
• Comparing the effects of age, BMI and gender on severe injury (AIS 3+) in motor-vehicle crashes.
• Hypothalamic PGC-1a Protects Against High-Fat Diet Exposure by Regulating ERa.

Findings Contrary to Hypotheses or Popular Beliefs

• RCT: No effect of a healthy corner store initiative on the purchases or weights of urban, low-income youth.
• RCT: No differential effects of High-GI diets, Low GI-Diets, or just adding potatoes to diet on weight loss.
• RCT: No effect of Acupoint Stimulation on Weight Reduction for Obesity.
• RCT: Intervention was associated with lower intake of fried foods and sodas (p < 0.05) and higher knowledge scores (p < 0.01) 18 months later, yet not significantly associated with improved physical activity or lower BMI.
• There have been conflicting reports about the relationship between gut microbiota taxonomy compositions and obesity.
• RCT: No significant effects (in a small study) of a pregnancy lifestyle intervention to prevent gestational diabetes risk factors in overweight Hispanic women.
• Food Intake Did Not Differ between Obese Women Who Are Metabolically Healthy or Abnormal.
• RCT: Internet-Based Healthy Eating Program Causes Increased Fruit & Vegetable Consumption, But No Discernable Effect on BMI.
• Myth: Losing Weight Too Fast.

Clinical

• RCT: effects of an integrated school–worksite weight control program.
• Diabetes Status and Race are Associated with Cardiovascular Risk Markers in Obese Adolescents.
• Hemoglobin A1c and the Progression of Coronary Artery Calcification Among Adults Without Diabetes.
• RCT: Academic Detailing Improves BMI Assessment in Pediatric Practices.

Epidemiology

• Infectobesity in the Polish Population - Evaluation of an Association between Adenoviruses Type 5, 31, 36 and Human Obesity.
• Availability of State-Based Obesity Surveillance Data on High School Students with Disabilities in the United States.
• Postpartum Weight Change in Lactating Women by Breast-feeding Duration.
• Access to Healthy Food Stores Modifies Effect [Association] of a Dietary Intervention.
• Overweight, food neophobia and food liking in children: is there a relationship?
• Inverse Correlation Between Helicobacter pylori Colonization and Obesity in a Cohort of Inner City Children.

Psychology

• Behavioral and Neural Valuation of Foods Is Driven by Implicit Knowledge of Caloric Content.
• Morality in everyday life.
• Worry or craving? A selective review of evidence for food-related attention biases in obese individuals, eating-disorder patients, restrained eaters and healthy samples.
• Approach Bias for Food Cues in Obese Individuals.

Food

• Breakfast-skippers have lower dopamine levels, which can lead to overeating and eventual weight gain.
• Red Pepper Can Enhance Energy Metabolism and Satiety.
• The relationship between bioactive components in breast milk and bone mass in infants.
• Type of fatty acids in maternal diets during pregnancy and/or lactation and metabolic consequences of the offspring.
• Timing of fat and liquid sugar intake alters substrate oxidation and food efficiency in male Wistar rats.
• Exposure to non-nutritive sweeteners during pregnancy and lactation: Impact in programming of metabolic diseases in the progeny later in life.

Drugs

• Zafgen Aims Obesity Drug At Rare, Deadly Disease.
• Off-Label Antiobesity Treatment in Patients without Diabetes with GLP-1 Agonists in Clinical Practice.
• Reports of Pathological Gambling, Hypersexuality, and Compulsive Shopping Associated With Dopamine Receptor Agonist Drugs.
• Why the Work of Dr. Nancy J. Sullivan Could Be Key to a Potential Ebola Vaccine.

Exercise

• Breaking-up Sedentary Time Is Associated With Physical Function in Older Adults.
• Decreased basal metabolic rate may reflect pituitary secretion disturbance in elite female athlete.

Surgery

• MGAT2 deficiency and vertical sleeve gastrectomy have independent metabolic effects in the mouse.
• Association of Race and Socioeconomic Status with Outcomes Following Laparoscopic Roux-en-Y Gastric Bypass.
• Weight loss required by the severely obese to achieve clinically important differences in health-related quality of life: two-year prospective cohort study.

Methods

• Establishing of a reliable multiple reaction monitoring-based method for the quantification of obesity associated comorbidities in serum and adipose tissue requires intensive clinical validation.
• On the use of log-transformation versus nonlinear regression for analyzing biological power laws.
• A method superior to adding percentiles when only limited anthropometric data such as percentile tables are available for design models.

Longevity

• Sugary soda and Cell Aging.
• Why caloric restriction alone won't help you live longer.
• TOR Signaling Couples Oxygen Sensing to Lifespan in C. elegans.
• Aging Research—Where Do We Stand and Where Are We Going?
• Aging and energetics' 'Top 40' future research opportunities 2010-2013.
• BMI and All-Cause Mortality in a Large Prospective Cohort of White and Black U.S. Adults.

Evolution, Energetics, & Ecology

• Impacts of extreme climatic events on the energetics of long-lived vertebrates: the case of the greater flamingo facing cold spells in the Camargue.
• Opportunity for selection in human health.
• Temperature acclimation rate of aerobic scope and feeding metabolism in fishes: implications in a thermally extreme future.
• Temperature effects induced by climate change on the growth and consumption by salmonines in Lakes Michigan and Huron.
• Among- and within-individual correlations between basal and maximal metabolic rates in birds.
• Let There Be Light.
• Modeling Growth Patterns of Swift Terns Using Non-Linear Mixed Effects Models.

Brown Fat

• Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors.
• Reduced brown adipose tissue thermogenesis during environmental interactions in transgenic rats with ataxin-3-mediated ablation of hypothalamic orexin neurons.

Energy Balance

• Energy requirements of adult dogs: a meta-analysis.
• Predictors of acute dietary compensation among sedentary women after free-living moderate intensity exercise.
• Effects of weight gain induced by controlled overfeeding on physical activity.

Policy Related

• Workplace wellness programs: how regulatory flexibility might undermine success.
• Who benefits from health system change?
• Health care transparency and economic theory.
• Why Bariatric Surgery Should be Given High Priority: An Argument from Law and Morality.

Commentary

• Retraction Watch: Authors retract green coffee bean diet paper touted by Dr. Oz.
• The scientific study of inspiration in the creative process: challenges and opportunities.
• Skin That Nobody Needs.
• Standardizing Portion Sizes May Not Benefit Human or Environmental Health.
• The university experiment – special section of Nature.
• BMI: Can’t Let It Go.
• Can Coupons Help Curb Obesity?
• Industry Influence, Integrity, and Respect.
• Concerning Limitations of Food-Environment Research: A Narrative Review and Commentary Framed around Obesity and Diet-Related Diseases in Youth.

Basic Science

• Leptin therapy alters appetite and neural responses to food stimuli in brain areas of leptin sensitive subjects without altering brain structure.
• Obesity May Speed Aging of the Liver, Study Suggests.
• Postnatal growth may identify infants genetically predisposed to obesity.
• Differential effects of caloric and carbohydrate restriction on prostate cancer in a mouse model.
• Diet Modification and Metformin Have a Beneficial Effect in a Fly Model of Obesity and Mucormycosis.
• The Role of Mio in the Drosophila Brain to Regulate Feeding and Metabolism.

General Science

• How to Make More Published Research True.
• Late onset temperature reduction can retard aging process in aged fish via a combined action of antioxidant system and IIS pathway.
• Recommendations from the NHLBI Working Group on Epidemiology.
• HSF-1-mediated cytoskeletal integrity determines thermotolerance and life span.
• Opportunity for selection in human health.
• 6,000-Year-Old Temple with Possible Sacrificial Altars Discovered.
• Physicists see potential dark matter from the Sun.
• Blinded with science: Trivial graphs and formulas increase ad persuasiveness and belief in product efficacy.
• Extremely Rare White Rhino Dies in Kenya—His Kind Nearly Extinct.
• Goliath Encounter: Puppy-Sized Spider Surprises Scientist in Rainforest.

Video

• Marie-Pierre St-Onge: The role of sleep restriction in weight management.
• Kim Gans: Fresh to You: An Innovative Public-Private Partnership to Increase Access to Fresh Fruits and Vegetables: History, lessons learned and Next Steps.
• Vicente Gilsanz: Expanding the role of imaging biomarkers to assess disease risk in children.
• Member Central Update:How R&D appropriations have stacked up in 2014.

Announcements

• New Book: Georges Vigarello. The Metamorphoses of Fat: A History of Obesity.
• 4th Short Course on Next-Generation Sequencing: Technology and Statistical Methods.
• Animal Obesity – causes, consequences and comparative aspects. 14-16 June 2015 in Uppsala, Sweden.
• Advances and Controversies in Clinical Nutrition in National Harbor, MD, December 4-6, 2014.
• American Society for Nutrition Scientific Sessions at EB 2015: Abstract deadline November 6.