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Featured

• RCT: Sildenafil Induces Browning of Subcutaneous White Adipose Tissue in Overweight Adults.
• Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.
• Can the Skin Make You Fat? A Role for the Skin in Regulating Adipose Tissue Function and Whole-body Glucose and Lipid Homeostasis.
• Body Weight, Perceived Weight Stigma and Mental Health Among Women at the Intersection of Race/ethnicity and Socioeconomic Status: Insights From the Modified Labelling Approach.

Headline vs Study

• Headline: No Sweat: Small Doses of Exercise May Ward Off Depression.
• Study: Self-reported Baseline Exercise is Associated with Lower Depression but Not Anxiety After 11 Years.

Contrary or Null Findings

• RCT: No Statistically Significant Effect on Obesity Indicators in a School-Based Weight Management Program Involving Parents Via MHealth for Overweight and Obese Children and Adolescents with Intellectual Disability.
• Overall, the Prevention Component Did Not Have an Impact on Students’ Measures of BMI Over One, Two, or Three Years in Interim Report of Healthy Harlem on the Prevalence of Child Overweight and Obesity (PDF).
• "Neither perceived nor objective community food environment measures were significantly associated with overweight/obesity in multivariable analyses."
• "Menu labeling resulted in no significant change in reported calories ordered/consumed in studies with full criteria adherence, nor the 14 studies analyzed with 1 unmet criteria, nor for change in total ordered carbohydrate, fat, and saturated fat (three studies) or ordered or consumed sodium (four studies)."
• "More studies need to be done to establish why market access did not enhance household food security contrary to the findings of other studies." (PDF)
• Although Dietary Source of Protein Has Significant Short Term Implications for Satiety and Metabolism, Manipulation of the Protein Component of a Single Meal of the Day Has Minimal Long Term Effects on Body Weight and Composition (in Rats).
• RCT: "no effect of offering overweight and obese pregnant women supervised exercise training during pregnancy on gestational weight gain."
• "It seems that overweightness or obesity was not associated with age of menopause, so it could not be said that females, who were overweight or obese compared to normal-weight females had earlier or later menopause."
• " a BMI in the overweight range of 25–29.9 kg/m2 is not associated with a poorer implantation rate or live-birth rate, nor is it associated with an increased risk of miscarriage when compared with a normal BMI range."

Basic

• Obesogenic Endocrine Disruptors and Obesity: Myths and Truths.
• Dietary Omega-3 and Omega-6 Polyunsaturated Fatty Acids Modulate Hepatic Pathology in Mice.
• Targeting ATP-Citrase Lyase in Hyperlipidemia and Metabolic Disorders: A Review.
• Lipolysis in Brown Adipocytes is Not Essential for Cold-Induced Thermogenesis in Mice.
• FGF19, FGF21, and an FGFR1/ß-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia.
• Suppression of Adipocyte Differentiation and Lipid Accumulation By Stearidonic Acid (SDA) in 3T3-L1 Cells.

Scientific Rigor & Scholarly Dialogue

• Big Breakfast Strikes Again.
• "Will a vegetarian diet during pregnancy drive your child to drugs and drink?"

Clinical

• What Bed Size Does a Patient Need? The Relationship Between BMI and Space Required to Turn in Bed.
• Long-term Impact of Weight Loss Intervention on Changes in Cognitive Function: Exploratory Analyses From the Action for Health in Diabetes RCT.
• RCT: Phone-based Mindfulness and Weight Loss Program.

Children and Adolescents

• RCT: Childhood Obesity Prevention Through a Physical Activity Intervention Among Schools in China: The Health Legacy Project of the 2nd World Summer Youth Olympic Games (YOG-obesity Study).
• The Transition Into Young Adulthood: A Critical Period for Weight Control.
• Patterns of Eating Disorder Pathology are Associated with Weight Change in Family-Based Behavioral Obesity Treatment.
• Childhood Obesity and Physical Activity-Friendly School Environments.
• Predictors and Outcomes of Mealtime Emotional Climate in Families with Preschoolers.

Surgery

• Long-Term Follow-Up of Autonomic and Enteric Measures in Patients Undergoing Vertical Banded Gastroplasty for Morbid Obesity.
• Diabetes Outcomes More than a Decade Following Sustained Weight Loss After Laparoscopic Adjustable Gastric Band Surgery.
• Significant Liver-Related Morbidity After Bariatric Surgery and Its Reversal-a Case Series.

Drugs

• Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People with Impaired Glucose Regulation.
• Metformin Affects Cortical Bone Mass and Marrow Adiposity in Diet-Induced Obesity in Male Mice.

Food & Diet

• Magnesium Intake, Quality of Carbohydrates, and Risk of Type 2 Diabetes: Results From Three U.S. Cohorts.
• Investigating an Incentive-Sensitization Model of Eating Behavior: Impact of a Simulated Fast-Food Laboratory.
• Can Chocolate Consumption Reduce Cardio-cerebrovascular Risk? A Systematic Review and Meta-analysis Chocolate Intake and Cardio-cerebrovascular Risk.
• Impact of Liver Fat on the Differential Partitioning of Hepatic Triacylglycerol Into VLDL Subclasses on High and Low Sugar Diets.
• Review: Egg Consumption, Cardiovascular Diseases and Type 2 Diabetes.
• Impact of Supplementation with a Food-derived Microbial Community on Obesity-associated Inflammation and Gut Microbiota Composition.

Caloric Restriction

• Timing of Caloric Intake During Weight Loss Differentially Affects Striatal Dopamine Transporter and Thalamic Serotonin Transporter Binding.
• Dietary Methionine Restriction Alleviates Hyperglycemia in Pigs with Intrauterine Growth Restriction By Enhancing Hepatic Protein Kinase B Signaling and Glycogen Synthesis.
• D-Allulose, a Stereoisomer of D-fructose, Extends Caenorhabditis Elegans Lifespan Through a Dietary Restriction Mechanism: A New Candidate Dietary Restriction Mimetic.

Exercise & Physical Activity

• Effectiveness of Remote Feedback on Physical Activity in Persons with Type 2 Diabetes: A Systematic Review and Meta-analysis of RCTs.
• Obesity Research Using Anti-gravity Treadmill.
• Stepping Up Weight Loss: Can Walking Help Dieters Shed Fat?
• RCT: Effects of Order and Sequence of Resistance and Endurance Training on Body Fat in Prepubescent Girls.
• Physical Activity, Obesity and Mortality: Does Pattern of Physical Activity Have Stronger Epidemiological Associations?

Economics & Sociology

• Interaction Between Social/Psychosocial Factors and Genetic Variants on BMI: A Gene-Environment Interaction Analysis in a Longitudinal Setting.
• Neighborhood Socioeconomic Disadvantage and BMI Among Residentially Stable Mid-older Aged Adults.
• Book Review: Nicole Taylor, Schooled on Fat: What Teens Tell Us About Gender, Body Image, and Obesity.

Epidemiology

• "Using large data with biomarkers in China, we show body mass index (BMI) to be positively correlated with higher person-level education if estimated using ordinary least squares. In stark contrast, fitting the same data within a multilevel model gives the complete opposite result."
• Meta-analysis on Shift Work and Risks of Specific Obesity Types.
• Hepatic but Not Extrahepatic Insulin Clearance is Lower in African American than in European American Women.
• Global Warming and Obesity: A Systematic Review.
• Changes in Adult BMI and Waist Circumference are Associated with Increased Risk of Advanced Colorectal Neoplasia.
• Cancers Associated with Overweight and Obesity Make Up 40 Percent of Cancers Diagnosed in the United States.
• Worldwide Trends in Body-mass Index, Underweight, Overweight, and Obesity From 1975 to 2016: A Pooled Analysis of 2416 Population-based Measurement Studies in 128·9 Million Children, Adolescents, and Adults.

Psychology & Neuroscience

• State and Trait Positive and Negative Affectivity in Relation to Restraint Intention and Binge Eating Among Adults with Obesity.
• Community Crime Exposure and Risk for Obesity in Preschool Children: Moderation By the Hypothalamic–Pituitary–Adrenal-Axis Response.
• Effects of 3-week Total Meal Replacement Vs. Typical Food-based Diet on Human Brain Functional Magnetic Resonance Imaging Food-cue Reactivity and Functional Connectivity in People with Obesity.
• Personal Variation in Preference for Sweetness: Effects of Age and Obesity.
• RCT: Social Media Peer Group for Mothers to Prevent Obesity From Infancy.
• Feeling Sated Can Become a Cue to Eat More (in Rats).

Equity and Disparities

• The Effect of Area Level Deprivation on Obesity in New Zealand: Analysis of the New Zealand Health Surveys.
• Hispanic Youth Visits to Food and Beverage Company Websites.

Stigma

• Body Image and Paranoia.
• Body Weight, Perceived Weight Stigma and Mental Health Among Women at the Intersection of Race/ethnicity and Socioeconomic Status: Insights From the Modified Labelling Approach.

Policy Related

• Use of International Classification of Diseases, Ninth Revision Codes for Obesity: Trends in the United States From an Electronic Health Record-Derived Database.
• The Relationship between Nicotine and Body Weight: Implications for Tobacco Regulatory Policy from Rats & Humans.
• Assessing the Role of Access and Price on the Consumption of Fruits and Vegetables Across New York City Using Agent-based Modeling.
• Is There a Link Between Availability of Food and Beverage Establishments and BMI in Mexican Adults?
• Who is Behind the Stocking of Energy-dense Foods and Beverages in Small Stores? The Importance of Food and Beverage Distributors.
• Approaching the Wicked Problem of Obesity: An Introduction to the Food System Compass.
• Why Chicago’s Soda Tax Fizzled After Two Months — and What It Means for the Anti-soda Movement.

Intergenerational Effects

• Associations of Maternal Weight Status Before, During, and After Pregnancy with Inflammatory Markers in Breast Milk.
• Maternal Obesity Heritably Perturbs Offspring Metabolism for Three Generations Without Serial Programming.
• Maternal High-fat Diet Induces Sex-specific Endocannabinoid System Changes in Newborn Rats and Programs Adiposity, Energy Expenditure and Food Preference in Adulthood.

Ecology, Evolution, & Energetics

• Zebra Finch Nestlings, Rather than Parents, Suffer From Raising Broods Under Low Nutritional Conditions.
• Heterogeneous Activity Causes a Nonlinear Increase in the Group Energy Use of Ant Workers Isolated From Queen and Brood.
• Amphipods (Gammarus Pseudolimnaeus) Prefer but are Harmed By a Diet of Non-native Leaves.
• Validation of the Doubly Labeled Water Method Using Off-axis Integrated Cavity Output Spectroscopy and Isotope Ratio Mass Spectrometry.
• Insulin-like Growth Factor 1 and Life-history Evolution of Passerine Birds.

Methods

• Influence of Body Composition on Disposition of the Highly Fat Distributed Compound as Analyzed By Physiologically-based Pharmacokinetic (PBPK) Modeling and Simulation.
• A Systematic Review of Methods to Measure Family Co-participation in Physical Activity.
• Measuring Glucose Cerebral Metabolism in the Healthy Mouse Using Hyperpolarized 13C Magnetic Resonance.
• Validity and Reliability of a 4-compartment Body Composition Model Using Dual Energy X-ray Absorptiometry-derived Body Volume.

Commentary

• Antibiotics in Livestock: Time for Slimming Down the Herd?
• Do Environmental Chemicals Make Us Fat?
• Addicted to Outrage: Can We Talk About Nutrition and Obesity?
• "Until strong evidence from well-conducted randomized controlled trials shows a robust, reproducible effect of parenting on childhood obesity, the research community must be cautious about implying that childhood obesity is a result of suboptimal parenting—be it too permissive or not sensitive enough—usually by mothers."
• The Sedentary (r)evolution: Have We Lost Our Metabolic Flexibility?
• Another Nobel Prize that Reflects on Obesity.
• ‘The Environmental Impact of Obesity: Longitudinal Evidence From the United States’.

General

• Ensuring Due Process in the IACUC and Animal Welfare Setting: Considerations in Developing Noncompliance Policies and Procedures for Institutional Animal Care and Use Committees and Institutional Officials.
• Addressing Scientific Integrity Scientifically.
• High-Deductible Health Plans Reduce Health Care Cost and Utilization, Including Use of Needed Preventive Services.
• US Navy Dolphins to Capture Vaquitas to Save Them From Extinction.
• Scientists List 50 Terms You May Be Confusing.
• Big Trouble Managing Mustangs.

Announcements

• Science Unbound Foundation Best Paper Awards Announced.
• UAB Seeks Post-doctoral Fellows for Its AHA Strategically Focused Research Center – Obesity Network: Intergenerational Transmission of Obesity.
• UAB’s NORC seeks post-doctoral fellows in obesity research.
• Research Position at Boston Children’s Hospital – Collaborate with Researchers at IU and UAB.
• OSP Scholar Spotlight: Daniella E. Chusyd.