Featured

• RCT: Carbohydrate-last Meal Pattern Lowers Postprandial Glucose and Insulin Excursions in Type 2 Diabetes.
• Obesity: Receptors Identified for a Weight Regulator.
• The Additional Costs and Health Effects of a Patient Having Overweight or Obesity: A Computational Model.

Headline vs Study

• Headline: Fat-regulating Enzyme Control Protects Against Disease, Say Researchers.
• Press release: A Fat-Regulating Enzyme Could Hold the Key to Obesity, Diabetes, Cancer, Other Diseases.
• Study: Activity of Phosphatidate Phosphatase (an Enzyme) Controls Expression of Phosphatidylserine Synthase (another Enzyme) for Membrane Phospholipid Synthesis... In Yeast. No Obesity, Diabetes, Cancer, or Other Diseases.

Contrary or Null Findings

• "Contrary to our hypotheses, results indicated that those living in less-favorable food and physical activity environments had greater improvements in diet, physical activity, and weight, compared to those living in more favorable environments."
• Botox Injections in Stomach Ineffective Against Obesity.
• "Higher milk fat consumption is associated with lower odds of severe obesity among Latino preschoolers. These results call into question recommendations that promote consumption of lower fat milk."
• High-fat Diet Reduces Weight Gain [but Increases Other Cardio-metabolic Indices] in Offspring of Normotensive and Hypertensive Rats.
• "In the total cohort, …[vitamin K] increased circulating carboxylated OC (cOC) but had no effect on body composition."
• Our Findings Indicate that Helminth Antigen-induced Eosinophilia Fails to Induce Profound Beiging of White Adipocytes.
• "Early-life exposure to SSBs conferred long-lasting impairments in hippocampal-dependent memory function later in life- yet had no effect on body weight, anxiety-like behavior, or glucose tolerance."
• "manipulations of the plate size had no effect on the expected fullness or the estimated intake of the Chinese and Korean respondents, as opposed to significant effects in Canadians and New Zealanders."

Basic

• Tissue Specific Modulation of Cyp2c and Cyp3a MRNA Levels and Activities By Diet-Induced Obesity in Mice: The Impact of Type 2 Diabetes on Drug Metabolizing Enzymes in Liver and Extra-Hepatic Tissues.
• Sexual Dimorphism, Age and Fat Mass are Key Phenotypic Drivers of Proteomic Signatures.
• The Effect of High Fat Diet on Daily Rhythm of the Core Clock Genes and Muscle Functional Genes in the Skeletal Muscle of Chinese Soft-shelled Turtle (Trionyx Sinensis).
• Ethanol-triggered Lipophagy Requires SQSTM1 in AML12 Hepatic Cells.
• Sympathetic Innervation is Essential for Metabolic Homeostasis and Pancreatic Beta Cell Function in Adult Rats.
• Caloric Restriction Stabilizes Body Weight and Accelerates Behavioral Recovery in Aged Sprague-Dawley Rats After Focal Ischemia.
• Effects of Obesity, Energy Restriction, and Neutering on the Faecal Microbiota of Cats.
• A Test of the Reward-contrast Hypothesis.
• Cold-sensing TRPM8 Channel Participates in Circadian Control of the Brown Adipose Tissue.

Scientific Rigor & Scholarly Dialogue

• Flawed Findings: Conspiracy Theories Masked as Academic Analysis.
• Pursuing Intellectual Honesty, Free of Bias and Conflicts.
• Too Indulgent or Not Sensitive Enough: Mothering in the Current Historical Era and Its Relevance to Childhood Obesity.
• Letter: Explaining the Obesity Paradox.
• Response: Explaining the Obesity Paradox.

Clinical

• Obesity and Sexual Dysfunction: Making the Connection.
• Fifty Years of Behavioral/Lifestyle Interventions for Overweight and Obesity: Where Have We Been and Where are We Going?
• Using Dietetic Interns to Facilitate a School-Based Obesity Intervention Can Lead to Sustained Reductions in Standardized BMI.
• Comparison of New Adiposity Indices for the Prediction of Body Fat in Hospitalized Patients.
• A Network Analysis Investigation of the Cognitive-behavioral Theory of Eating Disorders.
• Herbal Medicine for the Treatment of Obesity: An Overview of Scientific Evidence From 2007 to 2017.

Children and Adolescents

• Serum and Exhaled Breath Condensate Leptin Levels in Asthmatic and Obesity Children: A Pilot Study.
• Classification of Thinness, Overweight, and Obesity as a Function of the BMI and Fat Percentiles in Preschool and Primary School Children.

Surgery

• Improvement of Dyspnea After Bariatric Surgery is Associated with Increased Expiratory Reserve Volume.
• Comparison of the Recovery Profile Between Desflurane and Sevoflurane in Patients Undergoing Bariatric Surgery: A Meta-Analysis of RCTs.
• The Regulations and Mechanisms of Laparoscopic Sleeve Gastrectomy (LSG) for Obesity and Type 2 Diabetes: A Systematic Review.

Drugs

• PureTech's Gelesis Says Obesity Drug Achieved Weight Loss in Study.
• Inconsistences in Dosage Practice in Children with Overweight and Obesity.
• Longitudinal Trends and Predictors of Statin Use Among Patients with Diabetes.
• RCT: Effects of Liraglutide on Weight, Satiation, and Gastric Functions.

Food & Diet

• A High-Carbohydrate, High-Fiber, Low-Fat Diet Results in Weight Loss Among Adults at High Risk of Type 2 Diabetes.
• RCT: Effects of Timing of Whey Protein Intake on Appetite and Energy Intake in Healthy Older Men.
• Impact of Difructose Anhydride III, Raffinose, and Fructooligosaccharides on Energy Intake, Gut Hormones, and Cecal Fermentation in Rats Fed a High-fat and High-sucrose Diet.
• Influence of Dietary Macronutrients on Liver Fat Accumulation and Metabolism.
• Dairy Attenuates Weight Gain to a Similar Extent as Exercise in Rats Fed a High-Fat, High-Sugar Diet.
• Red Bull Energy Drink Increases Consumption of Higher Concentrations of Alcohol [in Rats].
• College-Aged Males Experience Attenuated Sweet and Salty Taste with Modest Weight Gain.

Caloric Restriction

• A Metabolomic Signature of Acute Caloric Restriction.
• Caloric Restriction Stabilizes Body Weight and Accelerates Behavioral Recovery in Aged Rats After Focal Ischemia.
• Caloric Restriction-Induced Decreases in Dopamine Receptor Availability are Associated with Leptin Concentration.
• Plasma FGF21 Levels in Obese Patients Undergoing Energy-restricted Diets or Bariatric Surgery: A Marker of Metabolic Stress?
• Effect of Caloric Restriction on Gut Permeability, Inflammation Markers, and Fecal Microbiota in Obese Women.

Exercise & Physical Activity

• Effectiveness of Physical Activity Interventions in Achieving Behaviour Change Maintenance in Young and Middle Aged Adults: A Systematic Review and Meta-analysis.
• Mediterranean Diet, Physical Activity and Their Combined Effect on All-cause Mortality: The Seguimiento Universidad De Navarra (SUN) Cohort.
• One-Year Adherence to the Otago Exercise Programme with or Without Motivational Interviewing in Community-Dwelling Older People.
• High-intensity High-volume Swimming Induces More Robust Signaling Through PGC-1a and AMPK Activation than Sprint Interval Swimming in M. Triceps Brachia.
• RCT: Moderate Walking Enhances the Effects of an Energy-Restricted Diet on Fat Mass Loss and Serum Insulin in Overweight and Obese Adults.

Economics & Sociology

• Perceived Neighborhood Safety Related to Physical Activity but Not Recreational Screen-based Sedentary Behavior in Adolescents.
• How the Built Environment Affects Change in Older People's Physical Activity.
• Employment Status and Temporal Patterns of Energy Intake: Nutrition and Health Survey in Taiwan, 2005–2008.
• Family Food and Shape Messages: Capturing the Experiences of African-American Women.
• “Hunger Was Never Absent”: How Residential School Diets Shaped Current Patterns of Diabetes Among Indigenous Peoples in Canada.

Epidemiology

• Overweight is Associated with Lower Resting State Functional Connectivity in Females After Eliminating Genetic Effects: A Twin Study.
• Attention-Deficit/Hyperactivity Disorder Symptoms are Associated with Overeating with and Without Loss of Control in Youth with Overweight/Obesity.
• Does Public Transport Use Prevent Declines in Walking Speed Among Older Adults Living in England? A Prospective Cohort Study.
• Vital Signs: Trends in Incidence of Cancers Associated with Overweight and Obesity — United States, 2005–2014.

Equity and Disparities

• Neighborhood and Individual Sociodemographic Characteristics Associated with Disparities in Adult Obesity and Perceptions of the Home Food Environment.
• Examining Health Disparities By Gender: A Multimorbidity Network Analysis of Electronic Medical Record.
• When is a RCT Health Equity Relevant? Development and Validation of a Conceptual Framework.

Stigma

• Obesity is About Much More than an Unhealthy Lifestyle.
• Messages About Weight, Eating and Race in Super Bowl Advertisements.
• Differential Impact of Patient Weight on Pain-Related Judgments About Male and Female Chronic Low Back Pain Patients.

Policy Related

• Projecting the Impact of a Nationwide School Plain Water Access Intervention on Childhood Obesity: A Cost-benefit Analysis.
• The Nutrition Assistance Landscape in Afterschool Programs: Understanding the Gap Between Research, Policy, and Practice.
• Defining Obesity as a Disease.
• Obesity Prevention in the Supermarket-Choice Architecture and the Supplemental Nutrition Assistance Program.
• Mandate is Clear: Flawed Dietary Guidelines Process Must Be Reformed.
• Supplemental Nutrition Assistance Program (SNAP) Participation and Health Care Expenditures Among Low-Income Adults.
• Three Years Later, What is the Impact of the Gluten-Free Labeling Standard?
• The 2017 Treat and Reduce Obesity Act (TROA) Surpasses 110 Co-Sponsors in the U.S. House of Representatives.

Intergenerational Effects

• The Impacts of Maternal Iron Deficiency and Being Overweight During Pregnancy on Neurodevelopment of the Offspring.
• Gestational Hypoxia Disrupts the Neonatal Leptin Surge and Programs Hyperphagia and Obesity in Male Offspring in the Sprague-Dawley Rat.

Ecology, Evolution, & Energetics

• Who’s Eating Jellyfish? Penguins, That’s Who.
• Food Habits and Anthropogenic Supplementation in Coyote Diets Along an Urban-rural Gradient.
• Evidence of Developmental Niche Construction in Dung Beetles: Effects on Growth, Scaling and Reproductive Success.
• Biomarker of Burden: Feather Corticosterone Reflects Energetic Expenditure and Allostatic Overload in Captive Waterfowl.

Methods

• Monitoring Blood Sugar Without a Drop of Blood.
• Validation of Gait Characteristics Extracted From Raw Accelerometry During Walking Against Measures of Physical Function, Mobility, Fatigability, & Fitness.
• Measuring the Association Between BMI and All-Cause Mortality in the Presence of Missing Data: Analyses From the Scottish National Diabetes Register.
• Estimation of Chicken Intake By Adults Using Metabolomics-Derived Markers.

Mathematical and Quantitative

• Computational Content Analysis of Negative Tweets for Obesity, Diet, Diabetes, and Exercise. (pdf)
• Targeting Weight Loss Interventions to Reduce Cardiovascular Complications of Type 2 Diabetes: A Machine Learning-based Post-hoc Analysis of Heterogeneous Treatment Effects in the Look AHEAD Trial.

Commentary

• Time to Base Nutrition Policy on Science.
• Publish Houses of Brick, Not Mansions of Straw.

General

• Sloppy Reporting on Animal Studies Proves Hard to Change.
• Individual Heterogeneity Determines Sex Differences in Mortality in a Monogamous Bird with Reversed Sexual Dimorphism.
• Yes, You Get Wiser with Age.
• Is There an Ideal Amount of Income Inequality?
• Biological Clock Discoveries By 3 Americans Earn Nobel Prize.

Announcements

• NIH Announces New Clinical Trial Requirements for Grants and Contracts.
• UAB Seeks Post-doctoral Fellows for Its AHA Strategically Focused Research Center – Obesity Network: Intergenerational Transmission of Obesity.
• UAB’s NORC seeks post-doctoral fellows in obesity research.
• Research Position at Boston Children’s Hospital – Collaborate with Researchers at IU and UAB.