Featured

• A consensus guide to preclinical indirect calorimetry experiments.
• Meta-Analysis: Psychiatric and Cognitive Outcomes of Iron Supplementation in Non-Anemic Children, Adolescents, and Menstruating Adults.
• "Early supplementation with MFGM and MPL can effectively improve metabolic disorders induced by high fat, with MFGM having the most significant effect" in mice.
• Lac-Phe Induces Hypophagia by Inhibiting AgRP Neurons in Mice.
• RCT: Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment.

Headline vs Study

• Headline: Mounjaro 'Golden Dose' Revealed to Stop 'Food Noise'.
• Study: Cross-Sectional Review of Data from 100 Patients Prescribed Mounjaro from One Online Pharmacy. Current Dose, Starting Body Mass Index (BMI) and Percentage of Body Weight Lost Extracted; Food Noise Was Not Assessed.

Contrary or Null Findings

• RCT: In "Evaluation of Five Novel Intervention Components in Online Obesity Treatment: Outcomes of a Randomized Factorial Experiment," "No intervention component independently improved weight loss..."
• The Combination of Mechanical Overload (OL) and High-Intensity Interval (HIIE) Training Does Not Interfere with Skeletal Muscle Hypertrophy Compared with OL Alone. MTOR Signaling Is Not Suppressed by HIIE in Mice.
• Energy Expenditure of Male Soccer Players from an English Premier League Team Does Not Differ between One-Game and Two-Game Per Week Microcycles.
• RCT: "Commercially relevant 16:0-rich IE fats consumed at 10% energy for a 6-week period do not adversely affect total:HDL cholesterol ratio or other CMD risk markers compared with 18:0-rich fats."
• RCT: "inclusion of up to 71 g/day of lean beef in a Mediterranean-Style diet increased gut microbiota diversity and lowered TMAO concentrations in healthy adults".
• RCT: No Significant Effects of Small-Quantity Lipid-Based Nutrient Supplements on Adolescent Physical Activity and Sedentary Behavior.
• RCT: "These findings suggest a limited ergogenic benefit of CHO and/or CAF mouth rinse through physiological and perceptual responses following sufficient food intake."
• RCT: "The results indicate that there was no statistical difference between groups for all variables" ...in "Effects of an Aquatic Exercise Protocol on Blood Pressure, Respiratory Function, and Functional Capacity in Individuals with Type 2 Diabetes."

Basic

• SerpinA3N in Leptin-Sensitive Neurons Is Required for Energy and Glucose Homeostasis and Autonomic Regulation.
• Principles of Cotranslational Mitochondrial Protein Import.
• The Physiology of MASLD: Molecular Pathways between Liver and Adipose Tissues.
• SOX4 Regulates Thermogenesis in Brown Adipose Tissue Via Independent Complexes with EBF2 and PPARγ.

Scientific Rigor & Scholarly Dialogue

• Article: Urine Stable Isotope Ratios are Associated with Proportional Intakes of Animal Protein and Added Sugars in a 15-Day Controlled Feeding Study.
• Editorial: Stable Isotopes Can Transform Nutritional Epidemiology - If We Let Them.
• Dr. Joseph Gordon Recognized with National Open Science Research Award for His Obesity Research.

Clinical

• The Effect of Habitual Sleep Duration on Weight Loss During a Behavioral Weight Loss Intervention in a Mediterranean Population.
• RCT: Effects of an App-Based Walking Program on Weight Management in Inflammatory Bowel Disease Patients.
• RCT: Effects of Dietary Energy Restriction of Ultra-Processed Foods Compared to a Generic Energy Restriction on the Intestinal Microbiota of Individuals with Obesity.

Children and Adolescents

• Childhood Allostatic Load Predicts Cardiometabolic Health in Adulthood.
• Association between Body Composition and Snack Nutrient Profile in Children.
• Lifting More Than Weights: Multi-Dimensional Health Benefits of Resistance Training in Children.

Surgery

• Evaluating National Trends in Bleeding Associated with Metabolic Bariatric Surgery over 7 Years.
• Enhancing Mood Post-Bariatric Surgery: Associations of Rosuvastatin with Vitamin D, Oxidative Stress, and Neurotransmitter-Related Outcomes in Rats.
• Retrospective Study: Thyroid Volume Stabilization and Nodule Progression After Bariatric Surgery.

Drugs

• Artemisia Argyi Essential Oil Modulates Lipid Metabolism Via Linoleic Acid and Glycerophospholipid Pathways in High-Fat Diet-Induced Obese Mice.
• Editorial: Drug Depots for Obesity Targeting Metabolism, Appetite, and Inflammation.
• Narrative review: Anti-Obesity Treatments with Anti-Inflammatory and Antioxidant Potential and Their Effects on Obesity-Related Metabolic and Cardiovascular Disorders.

Food & Diet

• Serum Galectin-9 and Decorin in Relation to Brain Aging and the Green-Mediterranean Diet.
• Histological Methods to Quantify Changes of White and Brown Adipose Tissue in Response to a High Content Fat Diet in Mice.
• Mediterranean Diet Adherence and Phase Angle: An Integrative Review on Cellular Health and Metabolic Risk.

Caloric and Dietary Restriction

• Disentangling the Distinct Effects of Calorie Restriction Versus Time-Restricted Eating on Longevity Pathways: Calorie Deficit or Fasting Window?
• Impact of Varied Dietary Macronutrient Ratios on the Nutrition Status of Swiss Albino Mice.

Exercise & Physical Activity

• Meta-Analysis: Virtual Reality-Enhanced Exergames for Weight Control.
• RCT: Adapted Basketball Training Improves Fitness and Motivation in Adolescents with Moderate Obesity.
• Retrospective Study: Childhood Obesity Beyond Individual Behaviors: Associations with Family Nutrition and Physical Activity.

Economics & Sociology

• Body Shape and Labor Market Dynamics: Analyzing Salary Information Asymmetry and Bargaining Power.
• Thesis: Understanding the Food Insecurity-Obesity Paradox: Socioeconomic and Geographic Influences.
• Dissertation: Understanding White-Collar Worker Experiences in Using Worksite Wellness Programs to Achieve Weight Loss.
• Review: Economic Impacts of Healthy Ageing Promotion and Disease Prevention in OECD Member Countries.

Epidemiology

• Association of Relative Fat Mass with the Incidence of Type 2 Diabetes: Over a Decade Follow-Up from the TLGS.
• A U-Shaped Relationship between BMI and the Risk of Elevated Liver Stiffness in Older People.
• Narrative Review: Weighty Consequences: Pollution's Hidden Weight in the Obesity Epidemic.
• Obesity and Inactivity Cluster the Strongest Risk Factor for the Development of Heart Failure in a Population-Based Study.
• High Prevalence of Overweight and Obesity Among Young Adults, Cameroon.
• Associations between Adverse Childhood Experiences and Obesity Among Young US Adults.
• Metabolic Health and BMI Phenotypes in Adults.

Psychology & Neuroscience

• Preprint: The Influence of Depression and Binge Eating Disorder in Inpatient Treatment of Obesity.
• Evaluation of Five Novel Intervention Components in Online Obesity Treatment: Outcomes of a Randomized Factorial Experiment.
• Meta-Analysis: Association between Screen Time and Overweight/Obesity.
• Preprint: Perceived Barriers and Facilitators to Engagement and Behavioral Enactment in Weight Management Interventions Among Racial and Ethnic Minorities.
• Preference for Behavior Change Strategies in RCTs: Evidence from Weight Management.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Systematic Review: Neighborhood Racial and Ethnic Segregation and Obesity.
• BMI Inequities Among Adults in Spain: An Intersectional Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy of Age, Sex/Gender, Immigration Status, and Education.

Stigma

• Moral Foundations and Obesity: The Role of Binding Vs. Individualizing Foundations in Shaping Weight Stigma.
• Maternity Care Providers' Attitudes and Beliefs Toward Weight and Body Size During Pregnancy.
• Review: Associations between Weight Discrimination and Health Outcomes by Racial and Ethnic Groups.

Policy Related

• Can Safe Routes to School and Transportation Policy Impact Child and Adolescent Health? A State-Level Policy Analysis.
• Consensus Statement on Front-of-Pack Nutrition Warning Labels on the High Fat, Sugar & Salt Food/Drink Products in India.
• Managing MASLD Through Preventive Hepatology: Integrating Policy Reform, Public Health and Personalised Care.

Intergenerational Effects

• Feasibility Study: Fresh Funds for Moms: Feasibility of a 12-Week Online Food as Medicine Grocery Prescription Program for Women with Food Insecurity and Gestational Diabetes.
• Revealing the Complexity of Immunobiological Shifts from Non-Pregnant to Pregnant State.
• Sexual Dimorphism in Offspring's Response to Maternal High-Fat Diet During Preconception and Diverse Fatty Acid Sources in Pregnancy and Lactation.

Ecology, Evolution, & Energetics

• Narrative Review: Weighty Consequences: Pollution’s Hidden Weight in the Obesity Epidemic.
• Genetic Variants May Explain Why Obesity Affects People Differently.

Methods

• Epidemiological Associations between Obesity, Metabolism and Disease Risk: Are BMI and Waist-Hip Ratio All You Need?
• Analysis of Long-Term Follow-Up of RCT with Departures from Assigned Treatments: Estimation of Metformin Effects on Diabetes and Its Complications in the Diabetes Prevention Program Outcomes Study.
• Preprint: Obesity Prevalence from 2005 to 2024: Comparison of Traditional and New Classification Approaches in a Swiss Population-Based Study.

Commentary

• Are GLP-1 Receptor Agonists a ‘Magic Bullet’ for Cancer?
• Current and Future Medications for Obesity Treatment.
• EASD: Can Semaglutide Put a Lid on Food Noise?
• On the Complexity of Moral Argument Understanding That Good People, for Good Reasons, Hold on to Ideas We Strongly Disagree With.
• Two Oral Tablets Race to the Market for Obesity Treatment.
• Opinion: Identification of a Reverse Crossover Point During Moderate-Intensity Exercise (>6hrs; 69% VO2max) in a World-Class Triathlete - A Secondary Analysis.
• They Shed Pounds with Weight-Loss Jabs - but Then Came the Loose Skin.
• Gut-Liver Axis: An Emerging Target for Exercise in Obesity Management.

General

• Iron Deficiency Without Anemia and Reduced Basal Ganglia Iron Content in Youths.
• Review: Prenatal Metabolomics Analysis and Fetal Congenital Anomalies and Genetic Conditions.
• Preprint: INSPECT-SR: A Tool for Assessing Trustworthiness of Randomised Controlled Trials.
• Study Finds Unexpected Ozempic, Zepbound Benefits for Psoriasis.
• Teflon Diet, Garlic Milk and Zebra Cows Triumph at 2025 Ig Nobel Prizes.
• Regenerate to "Rejuvenate": Insights From Adult Resident Stem Cells of Aged Flatworms and Mice.
• Review: Advancing Biological Understanding of Cellular Senescence with Computational Multiomics.
• Preprint: Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers.
• Chronic High Intensity Interval Training (HIIT) Exercise in Adolescent Rats Results in Cocaine Place Aversion and ΔFosB Induction.

Announcements

• NIH Workshop: Glucagon Physiology for the 21st Century Feb. 9 - 10, 2026.
• Mead Johnson Nutrition Hong Kong in collaboration with Medical Conscience, hosted a Paediatric Nutrition Symposium on September 15: "Clinical Benefits of Milk Fat Globule Membrane (MFGM) for Sustained Neurodevelopment at Age 5.5."