Featured

• Obesity and Thinness: Insights from Genetics.
• Diet Composition and Energy Intake in Humans.
• Requiem for Rimonabant: Therapeutic Potential for Cannabinoid CB1 Receptor Antagonists After the Fall.
• Gβγ-SNAP25 Exocytotic Brake Removal Enhances Insulin Action, Promotes Adipocyte Browning, and Protects Against Diet-Induced Obesity.

Headline vs Study

• Headline: For Jet Lag, a Hearty Breakfast in the New Time Zone May Help.
• Study: A Minimal Model of Peripheral Clocks Reveals Differential Circadian Re-Entrainment in Aging. No in Vivo Testing of Breakfast on Jet Lag.
• Headline Critique: “Study Finds” Breakfast Could Reduce Jet Lag - or Maybe Not.

Contrary or Null Findings

• Thesis: "We also fail to confirm our choice substitution effect hypothesis between full-service and limited- service restaurants, finding counter-intuitive outcomes in one of the three cities studied as well as in our Placebo test city. These findings suggest that public infrastructure projects are not a panacea, as they don’t translate into immediate spillover effects to the food system."
• "A 300 kcal/kg difference in dietary energy [density] (2,750–3,050 kcal/kg) does not affect short-term (36–52 wk of age) egg production in Hy-Line W-36 laying hens."
• "Contrary to expectations, oral Lactobacillus communities were not enriched by the XOS-supplemented diet" [in mice].
• "Orthorexia nervosa and healthy orthorexia assessed by most measures, contrary to the expectations, had significant positive associations with psychological distress indicated by stress, anxiety, and depression."
• Thesis: Contrary to Our Hypotheses, BMI Was Not Significantly Associated with Overall Emotion Recognition Accuracy.
• No Evidence of Compensatory Changes in Energy Balance, Despite Reductions in Body Weight and Liver Fat, During Dapagliflozin Treatment in Type 2 Diabetes Mellitus.
• "...our analysis of a nationwide claims database found no evidence that SGLT2 inhibitors increase UTIs in Japanese patients with DM, regardless of sex or age."
• RCT: "The primary out-come was weight loss and weight loss maintenance in the respective phases....Overall, there was ...no significant differences between groups..." on weight loss.

Basic

• URAT1 Is Expressed in Cardiomyocytes and Dotinurad Attenuates the Development of Diet-Induced Metabolic Heart Disease.
• Wnt10b Knockdown Promotes UCP1 Expression in Brown Adipose Tissue in Mice.
• Starch-Entrapped Microspheres Enhance Gut Microbiome-Mediated Anti-Obesity Effects of Resistant Starch in High-Fat Diet Induced Obese C57BL/6J Mice.
• Tricaprylin, a Medium-Chain Triglyceride, Aggravates High-Fat Diet-Induced Fat Deposition but Improves Intestinal Health.
• Branched-Chain Amino Acids Prevent Obesity by Inhibiting the Cell Cycle in an NADPH-FTO-M6A Coordinated Manner.

Scientific Rigor & Scholarly Dialogue

• Article: Effects of the Application of a Food Processing-Based Classification System in Obese Women: A Randomized Controlled Pilot Study.
• Letter: Incorrect Analysis in “Effects of the Application of a Food Processing-Based Classification System in Obese Women: A Randomized Controlled Pilot Study” Has Resulted in Incorrect Conclusions of Demonstrated Effects Where No Such Effects Have Been Demonstrated.
• "expert reaction to study looking at emulsifier E numbers and cardiovascular disease risk."
• Food Is Medicine! Regression to the Mean Proves It!
• Confounders, Biases, and the Sweetener Science.
• Good Vs. Bad Science: How to Read and Understand Scientific Studies.

Clinical

• Our Biology Working Against Us in Obesity: A Narrative Review on Implications for Management of Osteoarthritis.
• Giving Weight to Incretin-Based Pharmacotherapy for Obesity-Related Sleep Apnea: A Revolution or a Pipe Dream?

Children and Adolescents

• Perspective: Unintended Consequences of Glucagon-Like Peptide-1 Receptor Agonists Medications in Children and Adolescents: A Call to Action.
• The Association of Food Insecurity on BMI Change in a Pediatric Weight Management Intervention.
• Literature Review: Self-Esteem and Obesity in Children and Adolescents.
• Overeating Among Adolescents: Prevalence and Associations with Weight-Related Characteristics and Psychological Health.
• Evidence Base Update on Behavioral Treatments for Overweight and Obesity in Children and Adolescents.

Surgery

• Milestones in the Journey Towards Addressing Obesity; Past Trials and Triumphs, Recent Breakthroughs, and an Exciting Future in the Era of Emerging Effective Medical Therapies and Integration of Effective Medical Therapies with Metabolic Surgery.
• Adolescent Bariatric Surgery: The Need for Tailored Educational Materials.
• Bariatric and Metabolic Surgery in Patients with Low BMI: An Online Survey of 543 Bariatric and Metabolic Surgeons.

Drugs

• Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use.
• Novel Anti-Obesity Therapies and Their Different Effects and Safety Profiles: A Critical Overview.
• Anti-Inflammatory Effect of Ethanolic Extract from Tabebuia rosea (Bertol.) DC., Quercetin, and Anti-Obesity Drugs in Adipose Tissue in Wistar Rats with Diet-Induced Obesity.
• High-Throughput Screening of Lipase Inhibitors as Anti-Obesity Drugs on Liquid Crystal-Infused Porous Surfaces.

Food & Diet

• Adding Banana to Smoothie Reduces Bioavailability of Flavanols.
• RCT: Diet-Induced Weight Loss and Phenotypic Flexibility Among Healthy Overweight Adults.
• Diet-Derived and Diet-Related Endogenously Produced Palmitic Acid: Effects on Metabolic Regulation and Cardiovascular Disease Risk.
• Systematic Review: The Long-Term Effect of Maternal Obesity on the Cardiovascular Health of the Offspring.
• Clinical Review: Obesity and Malnutrition in Children and Adults.

Caloric and Dietary Restriction

• A Step Toward Precision Gerontology: Lifespan Effects of Calorie and Protein Restriction are Consistent with Predicted Impacts on Entropy Generation.
• Dietary Change Without Caloric Restriction Maintains a Youthful Profile in Ageing Yeast.

Exercise & Physical Activity

• Combined Endurance and Strength or Only Endurance Training? Effects of Training Mode on Neuromuscular Characteristics and Functional Abilities in Adolescent Girls with Obesity Enrolled in a Weight-Reduction Program.
• RCT: The Effects of an Exercise Intervention on Neuroelectric Activity and Executive Function in Children with Overweight/Obesity.

Economics & Sociology

• Factors Associated with Eating Behaviors in Older Adults from a Socioecological Model Perspective.
• Theorising Fatness as an Ordering Issue: A Conceptual Framework for Analysing the Construction of Fatness as Disorder.
• Ethnicity/Race, Parent Educational Attainment, and Obesity Associated with Prediabetes in Children.

Epidemiology

• Racial Disparities in Obesity-Related Cardiovascular Mortality in the United States: Temporal Trends from 1999 to 2020.
• Salivary Epigenetic Measures of BMI and Social Determinants of Health Across Childhood and Adolescence.
• Prepregnancy Overweight and Obesity and Long-Term Risk of Venous Thromboembolism in Women.
• Abstract: Insulin Resistance and Central Obesity Determine Hepatic Steatosis and Explain Cardiovascular Risk in Steatotic Liver Disease.
• BMI-Based Obesity Classification Misses Children and Adolescents with Raised Cardiometabolic Risk Due to Increased Adiposity.
• Association between Maternal Pre-Pregnancy BMI and Offspring’s Outcomes at 9 to 15 Years of Age.
• Investigating the Effects of Rurality on Stress, Subjective Well-Being, and Weight-Related Outcomes.

Psychology & Neuroscience

• Associations of Age and Gender with Dietary Patterns, Mindful Eating, Body Image and Confidence.
• Psychopathological Factors and Personality Dimensions on Dysfunctional Eating Behaviors in a Sample of Individuals with Obesity.
• Obesity Reduces Hippocampal Structure and Function in Older African Americans with the APOE-ε4 Alzheimer’s Disease Risk Allele.
• Energy Expenditure Homeostasis Requires ErbB4, an Obesity Risk Gene, in the Paraventricular Nucleus.

Equity and Disparities

• The Influence of Contested Racial Identity and Perceived Everyday Discrimination Exposure on BMI in US Adults.
• Explaining Gender Inequalities in Overweight People: A Blinder-Oaxaca Decomposition Analysis in Northern Sweden.

Stigma

• Distribution of Perceived Weight Stigma and Its Psychological Impact on Obese People in Saudi Arabia.
• Assessment of Obesity Stigma and Discrimination Among Spanish Subjects with a Wide Weight Range: The OBESTIGMA Study.
• Constant Vigilance: The Impact of Weight Stigma, Vigilance, and Internalization on Maladaptive Eating Behaviors.

Policy Related

• Effectiveness of a School Drinking Water Promotion and Access Program for Overweight Prevention.
• Social Media Food Ads Hype and Adolescent Obesity Upsurge in Nigeria.
• Government Policies to Improve Food Environments: A Population and Equity Lens.
• School Nutrition Environment and Services: Policies and Practices That Promote Healthy Eating Among K-12 Students.
• Neighborhood Sociodemographic Characteristics and Healthfulness of Store Checkouts in Northern California.

Intergenerational Effects

• Preprint: The Developmental Origins of Health and Disease and Intergenerational Inheritance: A Scoping Review of Multigenerational Cohort Studies.
• Are Child and Parent Health Behaviors Associated with Childhood Obesity? A Descriptive and Methodological Study.

Methods

• Assessing Daily Energy Intake in Adult Women: Validity of a Food-Recognition Mobile Application Compared to Doubly Labelled Water.
• Establishing a Machine Learning Model for Predicting Nutritional Risk Through Facial Feature Recognition.
• Mixed Methods Feasibility and Usability Testing of a Childhood Obesity Risk Estimation Tool.

Commentary

• Targeting Obesity: Louisiana Partners Harness the Latest Science for Weight Loss.
• "Her work paved the way for blockbuster obesity drugs. Now, she’s fighting for recognition Svetlana Mojsov helped discover the hormone GLP-1. Why has she been excluded from its history?"
• ‘Willpower’ Is Not Enough: Time for a New Approach to Public Health Policy to Prevent Obesity.
• What Obesity Drugs and Antidepressants Have in Common.
• Diabetics, Rejoice: For Some, an Extra Cup of Coffee Might Be Just What the Doctor Ordered.
• How Fasting Can Lengthen Your Life.
• More Than Glycemic Control: SGLT2 Inhibitors May Extend Lung Cancer Survival.
• Elegant Explanations for Obesity Causes? Fuhgeddaboudit.
• The Science, Strengths, and Limitations of BMI.

General

• Hot Weight Loss Drugs Tested as Addiction Treatments.
• The Super-Recognizers: Some People Never Forget a Face.
• Heart Disease and Stroke Statistics—2023 Update: A Report from the American Heart Association.
• Balancing Risks and Benefits of Cannabis Use: Umbrella Review of Meta-Analyses of RCTs and Observational Studies.
• Sustainability of Knowledge Translation Interventions: The Evidence Lacks Evidence.
• The Opportunities and Pitfalls of ChatGPT in Clinical and Translational Medicine.
• Not What It Said on the Menu.
• Psychedelic Therapy for Depressive Symptoms: A Systematic Review and Meta-Analysis.
• A Systematic Review of Child Health, Developmental and Educational Outcomes Associated with High Mobility in Indigenous Children from Australia, Canada and New Zealand.

Announcements

• EUFIC Launches Food and Health Science Literacy Campaign to Combat Disinformation in the EU.
• National Institute of Health Awarded Assistant IU Biology Professor and Evolutionary Biologist Ryan Bracewell Nearly $2 Million to Study Chromosome Evolution and Rapid Y Chromosome Degeneration.