Featured

• Genotype-by-sex-by-diet Interactions for Nutritional Preference, Dietary Consumption, and Lipid Deposition in a Field Cricket.
• RCT: "Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars."
• Household Food Insecurity and Psychosocial Dysfunction in Ecuadorian Elementary Schoolchildren.
• RCT: First "evidence that an after-school setting has a better impact than a school-based setting in delivering a universal wellness prevention programme."

Headline vs Study

• Headline: Diabetes 'can Be Kept at Bay with a Glass of MILK Every Day at Breakfast Time'.
• Study: Acute Effects of Milk Proteins in Breakfast Meals on Postprandial Glucose, Satiety Ratings, and Subsequent Meal Intake. No Diabetes.

Contrary or Null Findings

• RCT: No effects of "Hit n Run, a video game based on the principles of Go/No-Go inhibition training, in young adults who reported disinhibited eating" on food-specific inhibitory control or caloric intake.
• Local Metabolic Hypothesis is Not Sufficient to Explain Coronary Autoregulatory Behavior.
• "Contrary to frequently reported unintended weight loss, our systematic review does not provide evidence for a lower energy or protein intake in patients with AD [Alzheimer's Disease] compared to controls."
• RCT: "Treatment with the dopamine agonist cabergoline does not prevent weight regain in obese individuals following weight loss."
• RCT: No Differential Effects of Two Preoperatory Weight Loss Diets on Hepatic Volume and Surgical Complications in Morbid Obese Bariatric Surgery Candidates.
• RCT: "Increasing the dose of calcium supplementation in RYGB operated patients with slightly elevated PTH levels does not normalize PTH levels, regardless of the type of supplement."
• RCT: No Evidence for Added Benefits of Ten Top Tips (10TT) is a Primary Care-led Behavioural Intervention Which Aims to Help Adults Reduce and Manage Their Weight By Following 10 Weight Loss Tips Beyond Usual Care.
• "Correlations between all nutritional intake and [gastrointestinal symptoms] were not statistically significant" during a marathon in recreational runners.

Basic

• SGLT2 Knockout Prevents Hyperglycemia and is Associated with Reduced Pancreatic β-cell Death in Genetically Obese Mice.
• Dietary Stearic Acid Regulates Mitochondria in Vivo in Humans.
• Disruption of G0/G1 Switch Gene 2 (G0S2) Reduces Abdominal Fat Deposition and Alters Fatty Acid Composition in Chickens.
• Activation of Histone Deacetylase 4 (HDAC4) in Adipocytes Leads to Beige Adipocyte Expansion and Reduced Adiposity in H4-TG Mice.
• Intestinal Metabolism and Bioaccumulation of Sucralose in Adipose Tissue in the Rat.
• CD38 Deficiency Protects Heart From High Fat Diet-Induced Oxidative Stress Via Activating Sirt3/FOXO3 Pathway.
• Absence of Leptin Signaling Allows Fat Accretion in CF Mice.
• Emerging Role of AMPK in Brown and Beige Adipose Tissue (BAT): Implications for Obesity, Insulin Resistance, and Type 2 Diabetes.

Scientific Rigor & Scholarly Dialogue

• Erratum. Reduction in the Incidence of Type 2 Diabetes with the Mediterranean Diet: Results of the PREDIMED-Reus Nutrition Intervention Randomized Trial.
• Erratum. Mediterranean Diet, Retinopathy, Nephropathy, and Microvascular Diabetes Complications: A Post Hoc Analysis of a Randomized Trial.
• Trade-offs in Rigor and Generalizability in a Diet Trial of Glycemic Control in Adults with Type 2 Diabetes Using Whole Foods and Dietary Supplements.
• Letter. Effects of Probiotics on Body Weight, BMI, Fat Mass and Fat Percentage in Subjects with Overweight or Obesity: A Systematic Review and Meta-analysis of RCTs.
• Why is So Much Nutrition Research Kept Confidential Before Publication?

Clinical

• Effect of Obesity on Labor Duration Among Nulliparous Women with Epidural Analgesia.
• RCT: "Short-medium-long-term efficacy of interdisciplinary intervention against overweight and obesity."

Children and Adolescents

• Infant Breastfeeding and Childhood General, Visceral, Liver, and Pericardial Fat Measures Assessed By Magnetic Resonance Imaging.
• Relationship of BMI Z Score to Fat Percent and Fat Mass in Multiethnic Prepubertal Children.
• The Association Between Household Food Insecurity and BMI: A Prospective Growth Curve Analysis.

Surgery

• IFSO Worldwide Survey 2016: Primary, Endoluminal, and Revisional Procedures.
• Laparoscopic Sleeve Gastrectomy Resolves NAFLD: Another Formal Indication for Bariatric Surgery?

Drugs

• RCT: The Benefits of Adding Metformin to Tamoxifen to Protect the Endometrium.
• A Good Look at Semaglutide for Obesity.
• Pharmacological Action of a Pregnane Glycoside, Russelioside B, in Dietary Obese Rats: Impact on Weight Gain and Energy Expenditure.

Food & Diet

• Phytoestrogen Supplementation and Body Composition in Postmenopausal Women: A Systematic Review and Meta-analysis of RCTs.
• Dietary Carbohydrate Intake and Mortality: A Prospective Cohort Study and Meta-analysis.
• Ketogenic Ratio Determines Metabolic Effects of Macronutrients and Prevents Interpretive Bias.
• Metabolites as Regulators of Insulin Sensitivity and Metabolism.

Caloric Restriction

• Moderate Calorie Restriction Attenuates Age‑associated Alterations and Improves Cardiac Function By Increasing SIRT1 and SIRT3 Expression.
• Caloric Restriction Counteracts Chemotherapy-induced Inflammation and Increases Response to Therapy in a Triple Negative Breast Cancer Model.
• Time-restricted Feeding Suppresses Excess Sucrose-induced Plasma and Liver Lipid Accumulation in Rats.
• Overfed Mice Got Rhythm.

Exercise & Physical Activity

• RCT: Effects of Aerobic Exercise and Vitamin C Supplementation on Rhinitis Symptoms in Allergic Rhinitis Patients.
• Consensus Statement on Placebo Effects in Sports and Exercise: The Need for Conceptual Clarity, Methodological Rigour, and the Elucidation of Neurobiological Mechanisms.
• Replacing Sedentary Time: Meta-analysis of Objective-Assessment Studies.
• RCT: Pre-Exercise Breakfast Ingestion Versus Extended Overnight Fasting Increases Postprandial Glucose Flux After Exercise in Healthy Men.
• The Multivariate Physical Activity Signature Associated with Metabolic Health in Children.

Economics & Sociology

• Neighborhood Food Environment, Dietary Fatty Acid Biomarkers, and Cardiac Arrest Risk.
• The Impact of Rising Food Prices on Obesity in Women: A Longitudinal Analysis of 31 Low-income and Middle-income Countries From 2000 to 2014.

Epidemiology

• Working Times and Overweight: Tight Schedules, Weaker Fitness? (pdf)
• Morning Preference and Better Sleep Linked to Reduced Type 2 Diabetes Risk.
• Coronary Microvascular Dysfunction: A Preferred Risk Marker in Obesity?
• Adolescent Weight and Electronic Vapor Product Use: Comparing BMI-Based with Perceived Weight Status.
• Analysis of Changes in Adiponectin Levels and Abdominal Obesity After Smoking Cessation.
• Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes.
• The All-Cause Mortality and a Screening Tool to Determine High-Risk Patients Among Prevalent Type 2 Diabetes Mellitus Patients.

Psychology & Neuroscience

• Framing Obesity: Effects of Obesity Labeling and Prevalence Statistics on Public Perceptions.
• Sociocentric Social Networks and Overweight/obesity in the Classroom.
• Ripple Effects of Communities Childhood Obesity Prevention.

Equity and Disparities

• Public Health Interventions in the Era of Childhood Obesity and Other Racial Health Disparities.
• Racial/Ethnic Differences in the Effectiveness of a Multisector Childhood Obesity Prevention Intervention.
• Socioeconomic Inequalities in Weight, Height and BMI From Birth to 5 Years.

Stigma

• How and Why Weight Stigma Drives the Obesity ‘epidemic’ and Harms Health.
• Preferred Weight‐related Terminology By Parents of Children with Obesity.
• Weight Bias and Stigma in Children.
• Framing Obesity: Effects of Obesity Labeling and Prevalence Statistics on Public Perceptions.

Policy Related

• A Toolkit for Data Transparency Takes Shape.
• Understanding and Overcoming the Challenge of Obesity and Overweight in the Armed Forces.

Ecology, Evolution, & Energetics

• Impacts of Forests on Children’s Diet in Rural Areas Across 27 Developing Countries.
• Metabolic Rates, Climate and Macroevolution: A Case Study Using Neogene Molluscs.
• Terrestrial Locomotion of the Northern Elephant Seal (Mirounga Angustirostris): Limitation of Large Aquatically Adapted Seals on Land?
• Role of the Circadian Clock in the Metabolic Syndrome and Nonalcoholic Fatty Liver Disease.

Methods

• Cardiorespiratory Fitness in Children: Evidence for Criterion-referenced Cut-points.
• Comparison of Logistic Regression with Machine Learning Methods for the Prediction of Fetal Growth Abnormalities: A Retrospective Cohort Study.
• Estimating Energy Expenditure From Wrist and Thigh Accelerometry in Free-living Adults: A Doubly Labelled Water Study.
• Narrative Review of New Methods for Assessing Food and Energy Intake.

Commentary

• Genetic Susceptibility to the “obesogenic” Environment: The Role of Eating Behavior in Obesity and an Appetite for Change.
• Get Up and Move Around, Children!
• Ketogenic Leftovers, Reheated- Just for You!
• Loose Connections Between Dietary Guidelines and Reality.
• Looking for a Sweet Spot for Carbs.
• Why do Some Microbes Live in Your Gut While Others Don’t?
• The Toll of America’s Obesity.

General

• RP: CB Study Decides to Scale Down Studies to Replicate.
• Open Science By Design: Realizing a Vision for the 21st Century.
• Biological Embedding of Neighborhood Disadvantage and Collective Efficacy: Influences on Chronic Illness Via Accelerated Cardiometabolic Age.
• Important Factor May Be Missing in Models Used to Predict Spread of Epidemics From Climate Change.
• Hormonal Correlates of Exploratory and Play-related Behavior in Domestic Dogs.
• Populating the Data Ark: An Attempt to Retrieve, Preserve, and Liberate Data From the Most Highly-cited Psychology and Psychiatry Articles.
• Scalable and Accurate Deep Learning with Electronic Health Records.

Video & Audio

• David Sabatini, M.D., Ph.D.: Rapamycin and the Discovery of MTOR — the Nexus of Aging and Longevity?
• Audio: Rapamycin and Dogs — Man’s Best Friends? — Living Longer, Healthier Lives and Turning Back the Clock on Aging and Age-related Diseases.

Announcements

• IU Bloomington School of Public Health Initiates Major Wave of Faculty Recruitment – Tenure-track positions available in every department and two department chairs open – see multiple listings posted here.
• UAB’s NORC Seeks Post-doctoral Fellows in Obesity Research.
• UAB Seeks Post-doctoral Fellows for Its AHA Strategically Focused Research Center – Obesity Network: Intergenerational Transmission of Obesity.