08/20/21
Featured
- Daily Energy Expenditure Through the Human Life Course.
- Ablation of Sam68 in Adult Mice Increases Thermogenesis and Energy Expenditure.
- The Effect of Endurance Training on Non-Alcoholic Fatty Liver Disease in Mice.
- Mito-Mendelian Interactions Alter in vivo Glucose Metabolism and Insulin Sensitivity in Healthy Mice.
Headline vs Study
- Headline: New Drug Corrects Diet-Induced Obesity by Keeping Mitochondria from Fragmenting.
- Press-Release: Targeting Mitochondria Shows Promise in Treating Obesity: Molecule That Changes the Shape of Mitochondria Corrects Obesity.
- Study: Drug-Like Sphingolipid SH-BC-893 Opposes Ceramide-Induced Mitochondrial Fission and Corrects Diet-Induced Obesity... In Mice.
Contrary or Null Findings
- No Effect of Monosodium Glutamate on Subjective Appetite and Subsequent Energy Intake in Children of Different Ethnicities.
- RCT: Unsupervised Exercise Training Was Not Found to Improve the Metabolic Health or Phenotype over a 6-Month Dietary Intervention.
- "Contrary to expectations, SMM and SMI were also higher in patients with NASH. Therefore, higher body fat, rather than sarcopenia and SO, might be decisive for development of NASH in patients with obesity."
- "Contrary to our hypothesis, DH mice were leaner, had increased energy dissipation, a pro-thermogenic profile in BAT and WAT, and improved carbohydrate metabolism compared to wild types."
- "In conclusion, prenatal exposure to preferred D-limonene and trans-anethole, or familiarity to eucalyptol did not help to overcome the innate aversion to eucalyptol and its negative effect on weanling piglets' BW."
- "The hypothesis that previously reported correlations between knee-extensor torque complexity and metabolic rate ([Formula: see text]) would be conserved at reduced joint angles (i.e., shorter muscle lengths)" was not confirmed.
- "In conclusion, frequency of consumption of boiled potatoes was not associated with all-cause or CVD mortality in the HUNT population in Norway."
- "No evidence was found that the 'prudent' pattern reduced cancer mortality."
Basic
- Distinct Changes in Gut Microbiota are Associated with Estradiol-Mediated Protection from Diet-Induced Obesity in Female Mice.
- Dynamic Interplay between Afadin S1795 Phosphorylation and Diet Regulates Glucose Homeostasis in Obese Mice.
- Hematopoietic Upstream Stimulating Factor 1 Deficiency Is Associated with Increased Atherosclerosis Susceptibility in LDL Receptor Knockout Mice.
- NOTUM Promotes Thermogenic Capacity and Protects Against Diet-Induced Obesity in Male Mice.
- Pinch Loss Ameliorates Obesity, Glucose Intolerance and Fatty Liver by Modulating Adipocyte Apoptosis in Mice.
Scientific Rigor & Scholarly Dialogue
- Letter: Expectancy Violation and COVID-19 Misinformation: A Comment on Bogomoletc and Lee's “Frozen Meat Against COVID-19 Misinformation: An Analysis of Steak-Umm and Positive Expectancy Violations”.
- Reply: A Response to Jon Agley’s “Expectancy Violation and COVID-19 Misinformation”.
- Article: Increasing Skeletal Muscle Carnitine Content in Older Individuals Increases Whole-body Fat Oxidation During Moderate-intensity Exercise.
- Letter: Does Carnitine Supplementation Truly Increase Whole-Body Fat Oxidation in Older Male Adults During Moderate-Intensity Exercise?
- Editorial: Strengthening Research Investigating Maternal Nutrition and Children's Neurodevelopment: How Can We Do It Better? Where Do We Go from Here?
Clinical
- Therapeutic Plasma Exchange in Patients with Severe Obesity (BMI >40): A Survey of Practices in the United States.
- Systematic Review: Peer-Supported Lifestyle Interventions on Body Weight, Energy Intake, and Physical Activity in Adults.
Children and Adolescents
- RCT: Comparing Two Different Family-Based Childhood Obesity Treatment Programmes in a Medically Underserved Region: Effectiveness, Engagement and Implementation Outcomes.
- Case-Control Study: Comparison of Family Related Factors, Nutritional-Behavioral Habits, and Lifestyle of Children with and without Obesity.
- "...the reported prevalences of childhood obesity in Australia between 1985 and 1995 were likely to have been overestimated, a result of the BMI-height bias coupled with the increase in average height during that period."
- Waist Circumference and Waist-To-Height Ratio in 7-Year-Old Children from the WHO Childhood Obesity Surveillance Initiative.
- Systematic Review: School-Based High-Intensity Interval Training Programs for Promoting Physical Activity and Fitness in Adolescents.
Surgery
- "Regulation of thioredoxin‑interacting protein could be part of the mechanism of diabetes remission after bariatric surgery."
- Intestinal-Derived FGF15 Protects Against Deleterious Effects of Vertical Sleeve Gastrectomy in Mice.
- Microstructural Changes in Human Ingestive Behavior After Roux-En-Y Gastric Bypass During Liquid Meals.
- "The presence of obstructive sleep apnoea does not influence either sleep duration or sleep quality in the bariatric surgical population. This suggests that clinically severe obesity itself may cause poor sleep."
- Systematic Review: Genetic Correlates of Weight Loss After Bariatric Surgery.
Drugs
- Weight Gain and Obesity Rates in Transgender and Gender-Diverse Adults Before and During Hormone Therapy.
- Obesity Potentiates the Risk of Drug-Induced Long QT Syndrome - Preliminary Evidence from WNIN/Ob Spontaneously Obese Rat.
Food & Diet
- RCT: Efficacy of Oral Cholecalciferol in Improving Renal and Vascular Functions in Vitamin D-Deficient Patients with Type 2 Diabetes Mellitus.
- Age and Sex Interact to Determine the Effects of Commonly Consumed Dairy Products on Postmeal Glycemia, Satiety, and Later Meal Food Intake in Adults.
- Alanine Alters the Carbohydrate Metabolism of Rainbow Trout: Glucose Flux and Cell Signaling.
- Effects of Miao Sour Soup on Hyperlipidemia in High-Fat Diet-Induced Obese Rats Via the AMPK Signaling Pathway.
- Spirulina Platensis Polysaccharides Attenuate Lipid and Carbohydrate Metabolism Disorder in High-Sucrose and High-Fat Diet-Fed Rats in Association with Intestinal Microbiota.
- Review: The Anti-Obesogenic Effects of Dietary Berry Fruits.
- Review: Protective and Ameliorating Effects of Probiotics Against Diet-Induced Obesity.
Caloric and Dietary Restriction
- The Effects of Graded Calorie Restriction XVII: Multitissue Metabolomics Reveals Synthesis of Carnitine and NAD, and TRNA Charging as Key Pathways.
- Bigu-Style Fasting Affects Metabolic Health by Modulating Taurine, Glucose, and Cholesterol Homeostasis in Healthy Young Adults.
Exercise & Physical Activity
- Standing Is Associated with Insulin Sensitivity in Adults with Metabolic Syndrome.
- Effect Modification of Cardiorespiratory Fitness, Obesity, and Physical Activity in Adults.
- Lack of Increase in Muscle Mitochondrial Protein Synthesis During the Course of Aerobic Exercise and Its Recovery in the Fasting State Irrespective of Obesity.
Economics & Sociology
- Systematic Review: The Effectiveness of Weight-Loss Lifestyle Interventions for Improving Fertility in Women and Men with Overweight or Obesity and Infertility.
- Systematic Review and Qualitative Synthesis: The Lived Experience of Patients with Obesity.
Epidemiology
- "Watching TV at least once a week was found to be a significant correlate of overweight and obesity in rural Timorese women of reproductive age."
- Adverse Childhood Experiences and Obesity over Time.
- Biomarker-Calibrated Macronutrient Intake and Chronic Disease Risk Among Postmenopausal Women.
- Substituting Meat or Dairy Products with Plant-Based Substitutes Has Small and Heterogeneous Effects on Diet Quality and Nutrient Security.
Psychology & Neuroscience
- "Children with obesity having greater initial impulsivity had better weight outcomes in treatment even after adjusting for initial appetitive drive."
- Weight Change Predicts College Adjustment and Depressive Symptoms Among First-Year College Students.
- Homeostasis and Food Craving in Obesity (Functional MRI Data).
- "...grandmother underweight prior to pregnancy is associated with an increased risk of ADHD among grandchildren..."
- Dynamic Regional Alterations in Mouse Brain Neuronal Activity Following Short-Term Changes in Energy Balance.
- Meta-Analysis: Weight Loss Interventions on Health-Related Quality of Life in Those with Moderate to Severe Obesity.
Equity and Disparities
- Fixed Effects Analysis: Socioeconomic Inequalities in the Food Environment and Body Composition Among School-Aged Children.
- Food Insecurity Is Associated with Higher Food Responsiveness in Low-Income Children: The Moderating Role of Parent Stress and Family Functioning.
- Sex-Specific Signature in the Circulating NLRP3 Levels of Saudi Adults with Metabolic Syndrome.
Stigma
- Systematic Review and Qualitative Synthesis: What are Weight Bias Measures Measuring? An Evaluation of Core Measures of Weight Bias and Weight Bias Internalisation.
- "Better If They Laugh with Me than at Me": The Role of Humor in Coping with Obesity-Related Stigma in Women.
Policy Related
- Digital Health and Precision Prevention: Shifting from Disease-Centred Care to Consumer-Centred Health.
- Changes in Food Purchases After the Chilean Policies on Food Labelling, Marketing, and Sales in Schools: A Before and After Study.
- From Data to Action: Combatting Childhood Obesity in Europe and Beyond.
- Qualifications and Competence to Prescribe Dietary Supplements: Perception of Fitness Instructors.
- Systematic Review: Undergraduate Medical Education Interventions Aimed at Managing Patients with Obesity.
Intergenerational Effects
- Prospective Relations between Maternal Emotional Eating, Feeding to Soothe, and Infant Appetitive Behaviors.
- Influence of Maternal Excess Weight Before Pregnancy on Breastfeeding and Weaning.
- Review: Should COVID-19 Mother Breastfeed Her Newborn Child?
- Review: Maternal Diet During Pregnancy and Lactation and Child Food Preferences, Dietary Patterns, and Weight Outcomes.
Ecology, Evolution, & Energetics
- Environmental Gradients Predict the Ratio of Environmentally Acquired Carotenoids to Self-Synthesised Pteridine Pigments.
- Cannibalism and Necrophagy Promote a Resource Loop and Benefit Larval Development in Insects of Temporary Waters.
Methods
- Design, Simulation, and Fabrication of an Ingestible Capsule with Gastric Balloon for Obesity Treatment.
- A Simple Method of Sarcopenia Detection Can Predict Adverse Cardiovascular Events in Patients with Abdominal Obesity.
- CUN-BAE Index as a Screening Tool to Identify Increased Metabolic Risk in Apparently Healthy Normal-Weight Adults and Those with Obesity.
- Magnesium Depletion Score (MDS) Predicts Risk of Systemic Inflammation and Cardiovascular Mortality Among US Adults.
- A Dietary Supplement Frequency Questionnaire Correctly Ranks Nutrient Intakes in US Older Adults When Compared to a Comprehensive Dietary Supplement Inventory.
Mathematical and Quantitative
- Anthropometric Indicators of Obesity. Are the New Indicators a Better Predictor of Body Fat Content Than BMI?
- Why Meals During Resting Time Cause Fat Accumulation in Mammals? Mathematical Modeling of Circadian Regulation on Glucose Metabolism.
- New Insights on the Interactions between Insulin Clearance and the Main Glucose Homeostasis Mechanisms.
Commentary
- Simple Energy Balance or Microbiome for Childhood Obesity Prevention?
- The Possible Mechanism of Physiological Adaptation to the Low-Se Diet and Its Health Risk in the Traditional Endemic Areas of Keshan Diseases.
- What We Think We Know About Metabolism May Be Wrong.
- Increases in Adiposity Among Children and Adolescents over Time: Moving Beyond BMI.
- Mobilizing Governments and Society to Combat Obesity: Reflections on How Data from the WHO European Childhood Obesity Surveillance Initiative are Helping to Drive Policy Progress.
- Intake of Ultraprocessed Foods Among US Youths Health Concerns and Opportunities for Research and Policy.
- Is Makeup Making Us Fat?
General
- RCT: Quality Control Questions on Amazon’s Mechanical Turk (MTurk).
- Envisioning Science for an Unknown Future.
- A Quantitative Decision Theory of Animal Conflict.
- The Light-To-Nutrient Ratio in Alpine Lakes: Different Scenarios of Bacterial Nutrient Limitation and Community Structure in Lakes Above and Below the Treeline.
- Cross-Continental Comparison of Parasite Communities in a Wide-Ranging Carnivore Suggests Associations with Prey Diversity and Host Density.
- Anaerobic Digestion of Sewage Sludge Has No Effect on Glucocorticoid and Anti-Progestagenic Activity but Increases Estrogenicity Three-Fold.
- "Overall, evidence supports our hypothesis that artificial lighting and noise pollution have been overlooked as long-term contributors to the spillover of zoonotic pathogens to humans in urban environments."
- Review: Advanced Glycation End Products (AGEs) and Its Receptor, RAGE, Modulate Age-Dependent COVID-19 Morbidity and Mortality.