Featured

• Leveraging Behavioral Genetics Methods to Accelerate Obesity Protection Discovery: The Augmented T0 Discordant Sibling Design.
• How Could Different Obesity Scenarios Alter the Burden of Type 2 Diabetes and Liver Disease in Saudi Arabia?
• RCT: Peanut Paste-Based Ready-To-Use School Meals Benefit Fluid Cognition in Northern Ghana.
• CLCF1 Signaling Restrains Thermogenesis and Disrupts Metabolic Homeostasis by Inhibiting Mitochondrial Biogenesis in Brown Adipocytes.

Headline vs Study

• Headline: Cognitive Behavioral Therapy Aids Outcomes One Year After Bariatric Surgery.
• Headline: No Weight Benefits with Phone-Based CBT a Year After Bariatric Surgery.
• Study: "This study found that tele-CBT delivered at 1 year after surgery resulted in no change in short-term weight outcomes [registered primary outcome] but improved disordered eating and psychological distress."
• Headline Critique: CBT After Metabolic Surgery: Tell the Story You Like.

Contrary or Null Findings

• RCT: Short-Duration Cold Exposure Decreases Fasting-Induced Glucose Intolerance but Has No Effect on Resting Energy Expenditure.
• No compelling evidence "that the dose of leucine ingested within the protein (leucine threshold hypothesis) and the subsequent plasma leucine variables (leucine trigger hypothesis; peak magnitude, rate of rise, and total availability) determine the magnitude of the postprandial postexercise MPS response."
• High Availability of Vegetables and Fruit Through Government-Funded School Lunch Is Not Reflected in 4th Grade Pupils' Intake.
• RCT: "contrary to our hypotheses, mindset did not affect snacking behaviour."
• RCT: "This study found no evidence of differences in changes from baseline in obesity measures, glucose regulation, and inflammation between...Intermittent dietary carbohydrate restriction versus calorie restriction..."
• RCT: "Eating a virtual meal does not appear to significantly reduce hunger in healthy individuals."
• "Neither dietary choline or L-carnitine altered body composition or energy metabolism in the lean or obese cats, as compared to control."
• RCT: "No effect of prefrontal transcranial direct current stimulation (tDCS) on food craving, food reward and subjective appetite in females displaying mild-to-moderate binge-type behaviour."

Basic

• Distinct Response of Adipocyte Progenitors to Glucocorticoids Determines Visceral Obesity Via the TEAD1-MiR-27b-PRDM16 Axis.
• E4orf1 Improves Adipose Tissue-Specific Metabolic Risk Factors and Indicators of Cognition Function in a Mouse Model of Alzheimer’s Disease.
• Obesity-Associated Microglial Inflammatory Activation Paradoxically Improves Glucose Tolerance.
• Modulatory Effect of Green Coffee Bioactives on High-Fat Diet–Induced Obesity in C57BL6 Mice Model.
• ACOT1 Deficiency Attenuates High-Fat Diet Induced Fat Mass Gain by Increasing Energy Expenditure.
• Lactobacillus oris Improves Non-Alcoholic Fatty Liver in Mice and Inhibits Endogenous Cholesterol Biosynthesis.

Scientific Rigor & Scholarly Dialogue

• Article: The Effect of Pistachio Supplementation on Metabolic Syndrome and Its Components in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
• Letter: Regarding “The Effect of Pistachio Supplementation on Metabolic Syndrome and Its Components in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials”.
• Reply: To Letter to the Editor Regarding “The Effect of Pistachio Supplementation on Metabolic Syndrome and Its Components in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials”.
• Silencing the Alarm on Aspartame and Cancer.
• Water Down Childhood Weight Gain in Elementary School?

Clinical

• Human-Centered Designed Communication Tools for Obesity Prevention in Early Life.
• Examine: Muscle Size & Strength.
• Sarcopenic Obesity and Cardiometabolic Health and Mortality in Older Adults: A Growing Health Concern in an Ageing Population.

Children and Adolescents

• The Effect of Poverty on the Relationship between Household Education Levels and Obesity in U.S. Children and Adolescents.
• BMI at Different Childhood Age Periods Associated with Cardiometabolic Disorders in Young Adulthood.
• Adherence to 24-Hour Movement Guidelines in Relation to the Risk of Overweight and Obesity Among Children and Adolescents.

Surgery

• The Impact of Bariatric Surgery on Liver Enzymes in People with Obesity: A 5-Year Observational Study.
• Bariatric and Metabolic Surgery in Patients Older Than 65 Years – a Multicenter Study.
• Effect of Bariatric Surgery on Metabolic Syndrome in Chinese Patients with Low BMI: A Propensity Score Matching Study.

Drugs

• Semaglutide Therapy Decreases Epicardial Fat Inflammation and Improves Psoriasis Severity in Patients Affected by Abdominal Obesity and Type-2 Diabetes.
• Role of Glucagon-Like Peptide-1 Receptor Agonists in Achieving Weight Loss and Improving Cardiovascular Outcomes in People with Overweight and Obesity.
• Beyond Weight Loss: Added Benefits Could Guide the Choice of Anti-Obesity Medications.

Food & Diet

• Modeling Digestion, Absorption, and Ketogenesis After Administration of Tricaprilin Formulations to Humans.
• A Secondary Outcome Analysis of an RCT Using a Mixed Lipid Emulsion Containing Fish Oil in Infants with Extremely Low Birth Weight: Cognitive and Behavioral Outcome at Preschool Age.
• RCT: When a Calorie Is Not a Calorie: Metabolic and Molecular Effects of Intermittent Fasting in Humans.
• Energy-Adjusted Dietary Inflammatory Index and Diabetes Risk in Postmenopausal Hispanic Women.
• Ultra-Processed Foods: Processing Versus Formulation.

Caloric and Dietary Restriction

• High-Fiber Diet Promotes Metabolic, Hormonal, and Satiety Effects in Women with Obesity on a Short-Term Caloric Restriction.
• RCT: Intermittent Dietary Carbohydrate Restriction Versus Calorie Restriction and Cardiometabolic Profiles.
• Universal DNA Methylation Age Across Mammalian Tissues.
• DNA Methylation Networks Underlying Mammalian Traits.

Exercise & Physical Activity

• Metabolic Pathway Modeling in Muscle of Male Marathon Mice (DUhTP) and Controls (DUC)-A Possible Role of Lactate Dehydrogenase in Metabolic Flexibility.
• Vigorous Intermittent Lifestyle Physical Activity and Cancer Incidence Among Nonexercising Adults - the UK Biobank Accelerometry Study.
• Extraordinary Claims in the Literature on High-Intensity Interval Training (HIIT): I. Bonafide Scientific Revolution or a Looming Crisis of Replication and Credibility?
• Effects of 2-Year Dietary and Physical Activity Intervention on Cognition in Children—A Nonrandomized Controlled Trial.
• Unpacking Differences in Post-Exercise Affective Experiences between Physically Underactive and Active Individuals.

Economics & Sociology

• “New Life and a New Way of Living”: Social Representations of Obesity and the Weight Loss Process in Women Who Underwent Bariatric Surgery.
• Relationships between Early-Life Family Poverty and Relative Socioeconomic Status with Gestational Diabetes, Preeclampsia, and Hypertensive Disorders of Pregnancy Later in Life.

Epidemiology

• Measured vs Estimated Resting Energy Expenditure in Children and Adolescents with Obesity.
• The Association between Dietary Pattern and Visceral Adiposity Index, Triglyceride-Glucose Index, Inflammation, and Body Composition Among Iranian Overweight and Obese Women.
• Age- and Sex-Related Trends in Body Composition Among Beijing Adults Aged 20–60 Years: A Cross-Sectional Study.
• Socio-Demographic Correlates of Unhealthy Lifestyle in Ethiopia: A Secondary Analysis of a National Survey.
• Mediation Effect of JAK2 Methylation on the Association between Sitting Time and Abdominal Obesity in Rural Adults.
• Differential Associations between Television Viewing, Computer Use, and Adiposity by Age, Gender, and Race/Ethnicity in United States Youth: A Cross-Sectional NHANES Analysis.

Psychology & Neuroscience

• Suppression of Food Intake by Glp1r/Lepr-Coexpressing Neurons Prevents Obesity in Mouse Models.
• Investigating Habenula Functional Connectivity and Reward-Related Activity in Obesity Using Human Connectome Project Data.
• Meta-Analysis: The Use of Non-Invasive Brain Stimulation Techniques to Reduce Body Weight and Food Cravings.

Equity and Disparities

• Social, Behavioral, and Metabolic Risk Factors and Racial Disparities in Cardiovascular Disease Mortality in U.S. Adults.
• The Effect of Poverty on the Relationship between Household Education Levels and Obesity in U.S. Children and Adolescents: An Observational Study.
• AI in Medicine-JAMA's Focus on Clinical Outcomes, Patient-Centered Care, Quality, and Equity.
• Glucose-Lowering Drug Use in Migrants and Native Danes with Type 2 Diabetes: Disparities in Combination Therapy and Drug Types.

Stigma

• Weight Stigma and Barriers to Effective Obesity Care.
• Ethical Considerations in Engaging Young People in European Obesity Prevention Research: The CO-CREATE Experience.
• American Association of Clinical Endocrinology Consensus Statement: Addressing Stigma and Bias in the Diagnosis and Management of Patients with Obesity/Adiposity-Based Chronic Disease and Assessing Bias and Stigmatization as Determinants of Disease Severity.

Policy Related

• Estimating the Unintended Impact of the North American Free Trade Agreement on U.S. Public Health.
• A Sugar-Sweetened Beverage Excise Tax in California: Projected Benefits for Population Obesity and Health Equity.
• Scoping Review: The Effectiveness of Food System Policies to Improve Nutrition, Nutrition-Related Inequalities and Environmental Sustainability.

Intergenerational Effects

• Sex-Specific Impact of Maternal Obesity on Fetal Placental Macrophages and Cord Blood Triglycerides.
• The Association between Maternal BMI and Serial Plasma Oxytocin Levels During Labor.
• Association between Metabolic Healthy Obesity and Female Infertility: The National Health and Nutrition Examination Survey, 2013-2020.

Ecology, Evolution, & Energetics

• Thesis: Dietary Indicators in the Tribosphenic Dentition and Their Implication for the Early Diversification of Therian Mammals.
• Senescent Immune Cells Accumulation Promotes Brown Adipose Tissue Dysfunction During Aging.
• Combined Threats of Climate Change and Contaminant Exposure Through the Lens of Bioenergetics.

Methods

• Using Machine Learning in Predicting Food Exchange List and the Exchangeable Portion.
• Deuterium Oxide Validation of Bioimpedance Total Body Water Estimates.

Commentary

• A Coronary Calcium Scan Predicts Risk of Death in Obesity.
• Decoding the Role of Leptin and Adiponectin in Obesity-Related Gastrointestinal Cancer.
• Adipocyte- and Monocyte-Mediated Vicious Circle of Inflammation and Obesity (Review of Cellular and Molecular Mechanisms).
• Opaque Transparency in the Promise to Share Data.
• Triple G Agonists — a Home Run for Obesity?
• The Potential Contribution and Challenges of Edible Grasshopper (Ruspolia differens) to Food and Nutrition Security in Uganda- a Literature Review.
• Non-Digestible Oligosaccharides-Based Prebiotics to Ameliorate Obesity: Overview of Experimental Evidence and Future Perspectives.
• An Issue of Disparities Embedded in the SELECT Trial.

General

• Sex Bias in Mortality Risk Changes over the Lifespan of Bottlenose Dolphins.
• The Heaviest Animal Ever? Massive Whale That Lived 40 Million Years Ago Found in Desert.
• Quantifying Population Dynamics Via a Geometric Mean Predator–Prey Model.
• The Effects of Animal Transfers on the Reproductive Success of Female White Rhinoceroses (Ceratotherium simum simum) Kept in European Zoos.
• How People Decide Who Is Correct When Groups of Scientists Disagree.
• Preprint: Major data analysis errors invalidate cancer microbiome findings.
• People's knowledge of and attitudes toward abortion laws before and after the Dobbs v. Jackson decision.
• Barbie and Body Image: A Scholar’s Take on the Research — and the Blockbuster Film.

Announcements

• Workshop: Dietary Patterns to Prevent and Manage Diet-Related Disease Across the Lifespan.