08/14/26
Featured
- Menopausal Duration and Relative Skeletal Muscle Index Predict Metabolic Inflexibility During Walking in Postmenopausal Women with Overweight/Obesity.
- A Central Role for Dietary Sugars in Human Evolution.
- Cannabinoid Modulation of Intestinal and Neuroimmune Dysregulation in Diet-Induced Obesity.
- The Hallmarks of Protein and Amino Acid Restriction in Aging and Longevity.
- Podcast: The New Science of Food Noise and Its Impact on Weight Loss.
Headline vs Study
- Headline: Brain Protein May Be Key Link between Obesity, Aging & Memory Loss.
- Study: Announcement About a Funded Grant to Study Obesity and Brain Aging... In Rats. No Study (Yet).
Contrary or Null Findings
- "Adherence to healthful PBDs [Plant-Based Diets] is associated with more favourable health outcomes irrespective of UPF content, suggesting that overall PBD quality may be more important than processing level for chronic disease prevention."
- RCT: "There were no significant between-group differences in microbiome health ranks of significantly changing species (increasing or decreasing)" in “Does a diverse whole-food plant-based dietary intervention improve gut microbiome composition, gut symptoms, energy and hunger in healthy adults?”
- Home-Delivered Diet Meal Service Combined with Dietary Counseling Not Statistically Significantly Better Than Dietary Counseling Alone.
- "Contrary to our initial predictions, our meta-regression models revealed no significant effects of host size (body mass) or temperature on the [Body Condition Index]-infection relationship after accounting for other drivers, such as parasite taxa and types of [Body Condition Index] measures used."
- Mixotrophy: An Updated View of Glucose Pathways in Cyanobacteria: Contrary to Previous Belief, the Cyanobacterium Synechocystis Lacks the Entner-Doudoroff Pathway for Glucose Metabolism.
- "Contrary to expectations, pregnant women without children (n=30) demonstrated greater knowledge about the minimum recommended duration of exclusive breastfeeding (87%) compared to pregnant women who were already mothers (n=22) (59%)."
- RCT: "In this trial, long-term aLA [α-lactalbumin] supplementation did not improve overall menstruation-related symptoms as assessed by the primary outcome."
- RCT: "Full-fat dairy shows benefits without raising body fat or cholesterol."
Basic
- Review: Mechanisms of Obesity-Related Kidney Disease: From Adipose Depot Biology to the Chymase-Aldosterone and Ghrelin-Leptin Axes.
- Nr4a3 Deficiency Disrupts MEK1-ERK1/2-Drp1 Signaling, Driving Adiposity and Glucose Intolerance in Male Mice.
- Attenuation of Diet-Induced Obesity and Impaired Glucose Homeostasis by IL-2/Anti-IL-2 Complex and Hyperbaric Oxygen.
- Duration-Dependent Gut Microbiota Disruption Drives Opposing Effects on Adipose Thermogenesis in Obese Mice.
- Ultrafiltered Mulberry (Morus alba L.) Leaf Albumin-Type Protein Attenuates High-Fat Diet-Induced Obesity in Mice by Remodeling Gut Microbiota and Metabolic Homeostasis.
- Obestatin and Its Fragment Analog Nt8U Influence Levels of Satiety Peptides in Diet-Induced Obese Mice.
Scientific Rigor & Scholarly Dialogue
- Authoring and Management of Transparent Research Integrity Assessments of RCT Publications Using LLM-Assisted Tools and Provenance Knowledge Graphs.
- Purified Diets Enable Experimental Rigor Through Compositional Control in Animal Research.
Clinical
- RCT: Intentional Weight Loss Before Endometrial Cancer Surgery to Support Postoperative Recovery.
- Unpacking Adiposity: A Narrative Critical Appraisal of Diverse Obesity Definitions.
- Hypothalamic Syndrome and Acquired Hypothalamic Obesity: From Fragmented Care to Integrated Multidisciplinary Management.
- Lipid Accumulation Product (LAP): A Key Indicator for Metabolic Dysregulation and Inflammatory Status in Obesity.
Children and Adolescents
- Eating Behavior Latent Profiles and Their Associations with Body Composition in Early Childhood: The CORALS Cohort.
- A Home-Based Progressive-Ratio Task for Assessing Food Reinforcement in Infancy: Developmental Sensitivity at 9 and 12 Months.
Surgery
- Association of Prior Metabolic Surgery with Outcomes After Hospitalization for Acute COPD Exacerbation.
- Experiences and Needs of Self-Health Management Among Patients Undergoing Bariatric Surgery.
- One-Year Weight Loss and Metabolic Outcomes After Laparoscopic Sleeve Gastrectomy in Adolescents Compared with Young Adults.
- Comparison of 90-Day Complications between Direct Anterior and Postero-Lateral Total Hip Arthroplasty in Patients with Obesity.
- Predictivity of Preoperative Weight Loss on Comorbidity Resolution in Bariatric Patients.
- Systematic Review: Efficacy of Bariatric Techniques in the Management of Pediatric and Adolescent Obesity.
Drugs
- Is Mandatory Lifestyle Intervention Before Pharmacological Obesity Management Needed?
- Meta-Analysis: Efficacy and Safety of High-Dose Retatrutide in Adults with Obesity and Type 2 Diabetes.
- Cardiovascular Prevention and the Implementation Gap in GLP-1 Receptor Agonist Therapies: After the Trials.
Food & Diet
- Review: Transitioning Towards Sustainable Diets: Pulses, Their Role in Modulating Gut Microbiota and Metabolic Health.
- Review: Molecular Mechanisms of Food Bioactive Constituents in the Management of Obesity and Hypertension.
- Review: High-Protein Diet: Biochemical Mechanisms, Metabolic Effects and Clinical Implications.
- Fibroblast Growth Factor 21: Possible Role in Growth and Metabolic Development During Early Life, Nutritional Interactions and Biological Actions.
- Vegan Diets and Dietary Energy Density.
- High Animal Protein and High Plant Protein Meals Differentially Alter Postprandial Plasma Amino Acid Concentrations but Not Glucose Homeostasis in People with Overweight/Obesity.
Caloric and Dietary Restriction
- Methionine-Supplemented Longevity Diet Increases Growth Hormone, GLP-1, and FGF21; Reduces Frailty; And Promotes Healthspan.
- Reduced Food Availability Amplifies Behavioral Depression and Impairs Locomotor Performance After Immune Challenge in Xenopus laevis.
- Atlas of Lysosomal Aging Reveals a Metabolite Signature Shared with Lysosomal Storage Disorders.
Exercise & Physical Activity
- Beyond MVPA Minutes: Physical Activity Phenotypes are Associated with Metabolic Profiles in Children with Obesity.
- RCT: Resistance Training and Its Cessation: Hormonal Responses, Muscle Thickness, Strength, and Muscular Endurance Adaptations to High- and Low-Load Protocols in Male Runners.
- Differential Neuromuscular Adaptations Following Multi-Joint vs Single-Joint Resistance Exercise Training.
- Relationships between Plasma Volume, Fluid Regulatory Hormones, and Maximal Oxygen Uptake Following Fixed-Workload Heat Acclimation in Men and Women.
- Effects of Exercise in a Fed or Fasted State on Mitochondrial Dynamics Regulators in the Skeletal Muscle of Recreationally Active Males.
- Acute Effects of Greek Yogurt Consumption on Bone Status Indices Following High-Intensity Interval Exercise in Premenopausal Females with Obesity.
Economics & Sociology
- Neighborhood, Race, and Cardiometabolic Health: A Legal Epidemiological Analysis of Greenville County, South Carolina.
- Socioeconomic Position, Genetic Susceptibility, and Epigenetic Profiles in Obesity Across the Life Course.
- Sociodemographic Correlates of BMI Among Adults with Obesity in Urban Lahore.
Epidemiology
- Prevalence, Comorbidities, and Mortality of Obesity Classes 4 and 5 in Adults.
- The Clinical Outcomes of Preclinical and Clinical Obesity Across Multiple Cohorts.
- Trends in Obesity Prevalence During Early Pregnancy in Gran Canaria, Spain, 1993 to 2022.
Psychology & Neuroscience
- Antipsychotic-Induced Obesity: A Literature Review of Pathophysiology, Genetics, and Management Strategies.
- Systematic Review: Brain Structural and Functional Changes in Childhood and Adolescent Obesity: A Systematic Review of MRI Studies.
- Meta-Analysis: Efficacy of Mindfulness-Based Interventions on Psychological Distress, Hyperandrogenism, and Metabolic Profile in Women with Polycystic Ovary Syndrome.
- Systematic Review: Digital Mental Health Interventions in Obesity Management.
Differential Population Circumstances, Exposures, Outcomes, and Effects
- Global Trends, Projections, and Inequalities in Overweight and Obesity Among Children and Adolescents from 1990 to 2040: A Modelling Study.
- Obesity in Migrant Populations: Epidemiology, Determinants, and Public Health Implications.
- Program and Family Predictors of Retention and Weight Loss Among Black Youth in a Pediatric Weight Management Program.
- Bridging the Gaps: A Critical Review of National Dietary and Lifestyle Guidelines for Pregnant Women in the Eastern Mediterranean Region.
- Real-World Experiences with Obesity Medication in the Netherlands: A Mixed Methods Study Among Patients and Professionals.
Ethics
Stigma
- Association of Internalised Weight Stigma and Physical Activity of Patients with Diabesity in a Primary Care Clinic in Hong Kong.
- Sleep Quality, Not Sleep Duration, Is Independently Associated with Internalized Weight Bias.
- Systematic Review: Seeing Size: A Systematic Review on Responses to Plus-Size Representation in Contemporary Media.
Policy Related
- Parents’ Reactions to a Social Media Marketing Campaign Promoting Universal School Meals Among Elementary-Aged US Children: A Content Analysis.
- Perspective: Shrinking Appetites: Will GLP-1 Adoption in High-Income Countries Accelerate Big Food’s Push Into Low- and Middle-Income Countries?
- Review: A Practical Perspective on Confronting the Obesity Epidemic: Public-Health Strategies.
Intergenerational Effects
- Review: Unhealthy Diets, Unhealthy Futures: How Modern Eating Patterns Endanger Maternal and Offspring Health.
- Optimizing the Postpartum Period to Support Lifelong Health for Women with Obesity.
- Neuroepigenetic Programming by the Maternal Environment.
Ecology, Evolution, & Energetics
- Podcast: The Evolutionary Science Behind Why You Can’t Lose Weight and How to Avoid 5 Modern Food Mistakes | Prof Daniel Lieberman.
- The Effects of Natural and Anthropogenic Stressors on the Behaviour, Physiology, and Life History of the Eastern Grey Kangaroo, Macropus giganteus, with Implications for Kangaroo Management.
Methods
- Lancet Definition vs Other Criteria for Obesity Diagnosis in Adults.
- Genome-Scale Modeling of the Influence of Microbiota-Derived Butyrate on the Regulation of Human Metabolism by the Histone Deacetylase SIRT1.
Mathematical and Quantitative
Commentary
- Podcast: How Much Weaker are You When Fasting?
- Podcast: Carbs Vs. Keto: Fueling Optimal Performance with Louise Burke, Ph.D.
- Podcast: How Much Does Cardio Hurt Weightlifting Power? With Emidio Pistilli.
- Podcast: Overrated/Underrated: Fat Loss Edition.
- Could an Ultra-Processed Food for Special Dietary Use Advance Personalized Medicine in Diabetic Nephropathy?
- Without Sugar, We Might Not Exist.
- Expert Reaction to Reports of Numbers of Deaths After Use of Obesity Drugs, as First Reported in the Times.
- Ultraprocessed Foods and Public Policy: The Argument for Use-Case Consideration.
General
- Podcast: "You've probably worried that the glyphosate on your bread is slowly harming you. The evidence points somewhere far less obvious and far more fixable."
- Podcast: AHA Special Edition: Hypertension Part I - Overview and Management.
- Podcast: The Joy of (Y): How Does Touch Lead to Pain or Pleasure?
- Podcast: "The FDA Voted for 6 Peptides. Its Own Scientists Said No."
- Podcast: Debunking Cochrane's 'Nurses Can Replace Hospital Physicians' Study.
- Cell-Specific Y-Box-Binding Protein-1 Drives Liver-Kidney Injury in Cholestasis.
- Sitting All Day Is Terrible for Us. Moving a Little Can Help.
Announcements
- Webinar: When the Provider is the Patient: An Obesity Specialist with Obesity Battles Bias and Stigma, Thomas George, Jr., Mon., August 24, 2026, 1-2 pm ET.
- Virtual Workshop: The planning committee on Community Engaged Research to Improve Diet, Nutrition, and Health will host a two-day, virtual workshop on September 3rd and 4th, 2026, from 11:00AM - 3:30PM ET each day.