Featured

• Muddy Water: Additional Observational Data Cannot Aid in Determining Whether There Is a Physiological Interaction between Low Vitamin B12 and High Folate in Cognitive Health.
• Metabolic Adaptation After Combined Resistance and Aerobic Exercise Training in Older Women.
• Risk of Type 2 Diabetes Among Individuals with Excess Weight: Weight Trajectory Effects.
• Valuing the Diversity of Research Methods to Advance Nutrition Science.

Headline vs Study

• Headline: Starting Babies on the ‘Nordic Diet’ Could Prevent Childhood Obesity, Study Says.
• Press Release: Nordic Lower-Protein Diet Could Hold Key to Instilling Healthier Eating Habits in Babies, New Study Finds.
• Conference Presentation: No abstract or publication publicly available. Release mentions no obesity outcomes other than observing "no negative effects on ... growth."

Contrary or Null Findings

• RCT: "Among participants in REDUCE-IT, allocation to icosapent ethyl had minimal effects on a series of biomarkers associated with atherosclerotic disease, whereas levels increased among those allocated to mineral oil."
• "Contrary to expectation, combining all micro and macro [in simulated] interventions appeared to have no impact or moderately increased the proportion of obesity/overweight among children."
• No Effect of Five Days of Bed Rest or Short-Term Resistance Exercise Prehabilitation on Markers of Skeletal Muscle Mitochondrial Content and Dynamics in Older Adults.
• "Contrary to our expectations, puma consumption of large species did not change with their trophic position, and pumas consumed more small prey and birds as apex predators."
• "Contrary to expectations, shorter juvenile telomere length was not associated with poor early-life conditions, but instead with better conditions, probably as a result of faster juvenile growth."
• "Contrary to our expectations, induced glucose levels were not protective. Increasing O-GlcNAc, either with Thiamet-G (TMG) or by suppressing the O-GlcNAcase (oga-1) gene does interfere with and therefore reduce Aβ- toxicity but not in the presence of high glucose."
• "Contrary to the first hypothesis, isokinetic peak strength showed stronger associations with all daily activities than did estimated 1-RM. In addition, the second hypothesis regarding the activity-specific pattern for the 1-RM with regards walking, chair rising and stair climbing measurements was not confirmed."
• No Evidence Supported a Significant Relationship between Combined Exposure to Phthalate Metabolites and Girls’ High BMI Trajectory.

Basic

• Male Marfan Mice are Predisposed to High Fat Diet Induced Obesity, Diabetes, and Fatty Liver.
• Severe Hyperprolactinemia Promotes Brown Adipose Tissue Whitening and Aggravates High Fat Diet Induced Metabolic Imbalance.
• Coagulation Factors Promote Brown Adipose Tissue Dysfunction and Abnormal Systemic Metabolism in Obesity.
• Modulation of Endoplasmic Reticulum Stress Via Sulforaphane-Mediated AMPK Upregulation Against Nonalcoholic Fatty Liver Disease in Rats.
• The Different Effects of Intramuscularly-Injected Lactate on White and Brown Adipose Tissue in Vivo.
• Obesity Elicits a Unique Metabolomic Signature in Human Airway Smooth Muscle Cells.
• FKBP11 Rewires UPR Signaling to Promote Glucose Homeostasis in Type 2 Diabetes and Obesity.

Scientific Rigor & Scholarly Dialogue

• Oops: The Mistaken Rush for Menu Calorie Labeling.
• Methodological Rigor and Transparency in Clinical Practice Guidelines for Nutrition Care in Critically Ill Adults: A Systematic Review Using the AGREE II and AGREE-REX Tools.
• Webinar: Are Federal Food Regulations Based on Sound Science?
• Current WHO Recommendation to Reduce Free Sugar Intake from All Sources to Below 10% of Daily Energy Intake for Supporting Overall Health Is Not Well Supported by Available Evidence.
• Viewpoint: France’s Le Monde Leads Media Frenzy Hyping Flawed Study Claiming Trace Pesticide Residues Wipe Out Benefits of Eating Fruits and Vegetables.
• Use of Pre-Post Treatment Values in Place of Between Group Comparisons Invalidates Meta-Analysis Findings. Commentary: "Can Millet Consumption Help Manage Hyperlipidemia and Obesity? A Systematic Review and Meta-Analysis".

Clinical

• Key Focus Group Themes to Inform Weight Management Interventions in Deep South African Americans.
• Cancer and Obesity: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022.
• Meta-Analysis: Effects of WB-EMS and Protein Supplementation on Body Composition, Physical Function, Metabolism and Inflammatory Biomarkers in Middle-Aged and Elderly Patients with Sarcopenic Obesity.
• Exploring a Need for a Cardiometabolic Disease Staging System as a Computerized Clinical Decision Support Tool: Qualitative Study.
• Nonmedical Interventions for Type 2 Diabetes: Evidence, Actionable Strategies, and Policy Opportunities.

Children and Adolescents

• Meta-Analysis: Effects of Strength Training on Body Fat in Children and Adolescents with Overweight and Obesity.
• Slower Progression to Central Puberty in Overweight Girls Presenting with Precocious Breast Development.
• Changes in Lifestyle and Obesity During the COVID-19 Pandemic in Korean Adolescents.
• Effectiveness of Active Video Games in Adolescents with Overweight and Obesity.
• Adverse Childhood Experiences, Health Behaviors, and Associations with Obesity Among Youth in the United States.
• Meta-Analysis: Associations between Different Cortisol Measures and Adiposity in Children.
• Prospective Associations of Tobacco Weight Control Beliefs with E-Cigarette Use Patterns in the PATH Study.

Surgery

• Meta-Analysis: The Impact of BMI on Long-Term Survival Outcomes After Surgery for Colorectal Cancer.
• Obesity and Bariatric Surgery in Australia: Future Projection of Supply and Demand, and Costs.
• Comparison of 5-Year Follow-Up Outcomes between Primary and Revision Roux-En-Y Gastric Bypasses After Open Vertical Banded Gastroplasty: An Inverse Propensity Score-Weighted Analysis.
• NASH Presence Is Associated with a Lower Weight Loss One and 2 Years After Bariatric Surgery in Women with Severe Obesity.

Drugs

• Ease-Of-Use and Acceptability of the Novel Semaglutide 2.4 Mg Single-Dose Pen-Injector in People with Overweight or Obesity in the STEP 8 Phase III Trial.
• Oral Semaglutide in Type 2 Diabetes Mellitus: Comprehensive Review, Critical Appraisal and Clinical Consideration of Its Use in India.

Food & Diet

• Effects of Probiotic Lactiplantibacillus plantarum IMC 510 Supplementation on Metabolic Factors in Otherwise Healthy Individuals with Overweight and Obesity.
• Cannabis Extract Effects on Metabolic Parameters and Gut Microbiota Composition in a Mice Model of NAFLD and Obesity.
• The Association between Plant-Based Diet Indices and Obesity and Metabolic Diseases in Chinese Adults: Longitudinal Analyses from the China Health and Nutrition Survey.
• β-Caryophyllene, a Dietary Cannabinoid, Protects Against Metabolic and Immune Dysregulation in a Diet-Induced Obesity Mouse Model.
• Medium-Chain Triglycerides Improve Lipid Metabolism in Obese Rats Through Increasing the Browning of Adipose Tissue Via Sympathetic Regulation.
• The Protective Role of Grape Seed in Obesity and Lipid Profile.
• RCT: The Effect of Curcumin on Hepatic Fat Content in Individuals with Obesity.
• Systematic Review: Role of Honey in Obesity Management.
• Intervention with Isoleucine or Valine Corrects Hyperinsulinemia and Reduces Intrahepatic Diacylglycerols, Liver Steatosis, and Inflammation in Ldlr−/−.Leiden Mice with Manifest Obesity-Associated NASH.
• Low-Carbohydrate Diet Score Is Associated with Improved Blood Pressure and Cardio-Metabolic Risk Factors Among Adults with Obesity.
• Healthier Diet Associated with Reduced Risk of Excessive Gestational Weight Gain: A Chinese Prospective Cohort Study.

Caloric and Dietary Restriction

• Body Weight, Diabetes Incidence Vascular Events and Survival 15 Years After Very Low Calorie Diet in Community Medical Clinics in the UK.
• The Effects of Time-Restricted Eating on Metabolism and Gut Microbiota: A Real-Life Study.
• When and What to Eat? A Scoping Review of Health Outcomes of Fasting in Conjunction with a Low-Carbohydrate Diet.

Exercise & Physical Activity

• Association of the “Weekend Warrior” and Other Leisure-Time Physical Activity Patterns with All-Cause and Cause-Specific Mortality.
• Physical Activity, Diet Quality and All-Cause Cardiovascular Disease and Cancer Mortality: A Prospective Study of 346 627 UK Biobank Participants.
• Using Combined Global Position System and Accelerometer Data Points to Examine How Built Environments and Gentrification are Associated with Physical Activity in Four Canadian Cities.

Economics & Sociology

• Struggling with Overweight or Obesity in Children – Fathers’ Perceptions and Experiences of Contributing Factors, Role and Responsibility.
• Associations of Acculturation and Gender with Obesity and Physical Activity Among Latinos.

Epidemiology

• Prenatal Single and Combined Exposure to Phthalates Associated with Girls’ BMI Trajectory in the First Six Years.
• Weight Loss in Newly Admitted Nursing Home Residents with Obesity.
• Weight-Change Trajectory in Relation to Cancer Risk: Findings from a Nationwide Cohort Study in South Korea.
• Risk Factors for Metabolic Syndrome in Individuals with Recent-Onset Psychosis at Disease Onset and After 1-Year Follow-Up.
• Association between Body Shape Index and Risk of Mortality in the United States.
• Associations of BMI with COVID-19 Vaccine Uptake, Vaccine Effectiveness, and Risk of Severe COVID-19 Outcomes After Vaccination in England: A Population-Based Cohort Study.
• Chronic Stress, Genetic Risk, and Obesity in U.S. Hispanic/Latinos.
• Direction and Magnitude of Social Jetlag are Associated with Obesity: Results from a Sample of Hospital Employees.
• Association between BMI and Risk of Gastric Cancer by Anatomical and Histological Subtypes in over 500,000 East and Southeast Asian Cohort Participants.
• Causal Associations of Obesity with Achilles Tendinopathy: A Two-Sample Mendelian Randomization Study.
• Association between Food Insecurity and Sarcopenia: Data from the 2011–2014 National Health and Nutrition Examination Survey.

Psychology & Neuroscience

• The Roles of Depression and Binge Eating in the Relationship between Adverse Childhood Experiences (ACEs) and Obesity.
• Risk Factors for Momentary Loss of Control and Subsequent Abandonment of Self-Devised Dietary Restraint Plans in Adults with Weight-Loss Goals: A Behaviour Sequence Analysis Approach.
• Choices between Money and Hyper-Palatable Food: Choice Impulsivity and Eating Behavior.
• Changes in Body Weight, Health Behaviors and Mental Health in Adults with Obesity During the COVID-19 Pandemic.
• Extending the Theory of Planned Behavior for Explaining Dietary Quality: The Role of Financial Scarcity and Food Insecurity Status.
• Estimating the Impact of Changes in Weight and BMI on EQ-5D-3L: A Longitudinal Analysis of a Behavioural Group-Based Weight Loss Intervention.
• Forming New Health Behavior Habits During Weight Loss Maintenance-The PREVIEW Study.
• Overweight and Executive Functions, Psychological and Behavioral Profile of Spanish Adolescents.

Equity and Disparities

• Mitochondrial Phenotype as a Driver of the Racial Dichotomy in Obesity and Insulin Resistance.
• Identity and Weight-Related Beliefs Among Black, Black/White Biracial, East Asian, Hispanic/Latino, Native American, South Asian, and White U.S. Americans.

Stigma

• Weighing Down My Career: Exploring Body Fat’s Impact on Career Success and Sex’s Moderating Role.
• Application of the Sociocognitive Model of Internalized Stigma to Weight: The Role of Weight Controllability Beliefs on Obligatory Exercise Engagement.

Policy Related

• Restaurant-Based Programming to Improve Healthy Food Access: Eat Fit Program Impact and Factors That Influence Adoption.
• Dairy Beloved: Why Indiana Should Stop Labeling Plant-Based Beverages as “Milk”.
• Congress Passes Bipartisan, Bicameral Keep Kids Fed Act.

Intergenerational Effects

• Pregnancy as a Fundamental Determinant of Child Health: A Review.
• Maternal Overweight and Obesity During Pregnancy: Strategies to Improve Outcomes for Women, Babies, and Children.
• Maternal Thyroid Disease and Pubertal Timing in Offspring: Novel Evidence for a Potential Association.
• Impaired Postprandial Adipose Tissue Microvascular Blood Flow Responses to a Mixed-Nutrient Meal in First-Degree Relatives of Adults with Type 2 Diabetes.
• Meta-Analysis: Association between Maternal Adiposity Measures and Infant Health Outcomes.

Ecology, Evolution, & Energetics

• Interindividual Variability of Human Thermoregulation: Toward Personalized Ergonomics of the Indoor Thermal Environment.
• Adipose Tissue Thermogenesis by Calcium Futile Cycling.
• A Simple Method Reveals Minimum Time Required to Quantify Steady-Rate Metabolism and Net Cost of Transport for Human Walking.
• Predators Minimize Energy Costs, Rather Than Maximize Energy Gains Under Warming: Evidence from a Microcosm Feeding Experiment.

Methods

• Methods Recently Used for the Assessment of Physical Activity in Children and Adolescents.
• The Glucose Tolerance Test in Mice: Sex, Drugs and Protocol.
• Systematic Review: Applying Image-Based Food Recognition Systems on Dietary Assessment.

Commentary

• Anti-Diabetic and Anti-Obesity: Efficacy Evaluation and Exploitation of Polyphenols in Fruits and Vegetables.
• Benefits of Time-Restricted Eating Depend on Age and Sex.
• Podcast: The Neuroscience of Obesity.
• House Appropriations Calls for Obesity Meds in Medicare.
• Global Cultures and Global Variations in Obesity.
• Intermittent Feeding and Circadian Rhythm in Critical Illness.
• Should Sleeve Gastrectomy Be a Preoperative Standard in Kidney Transplant Waitlisted Patients with a BMI of 35 kg/m²?
• Insulin Resistance in Children.
• Are COVID Vaccines Protecting People with Obesity?

General

• The Association between Aging-Related Monocyte Transcriptional Networks and Comorbidity Burden.
• The Efforts to Reform Research Bureaucracy to Date.
• Divergent effects of oxytocin on "mind-reading" in healthy males.
• Orcas are Eating Great White Sharks’ Livers Off South Africa’s Coast.
• SARS-CoV-2 Reinfections in a US University Setting, Fall 2020 to Spring 2021.
• Establishment of a Social Conditioned Place Preference Paradigm for the Study of Social Reward in Female Mice.
• What Is Mathematical Rigor?
• L-Theanine Alleviates Heat Stress by Regulating Glucose, Lipid, and Protein Metabolism.
• Extreme Heat Leads to Short- and Long-Term Food Insecurity with Serious Consequences for Health.
• Prospective Feasibility Study of a Mindfulness-Based Program for Breast Cancer Patients in the Southeastern US.
• Effectiveness of Incentives to Improve the Reach of Health Promotion Programs.

Announcements

• Fast-Growing Catalent Plots $350M Expansion and 1,000 New Hires in Bloomington, IN.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency And/or Statistical and Data Analytic Research in the Obesity, Nutrition or Aging Research Domains.