07/03/26
Featured
- Critical Review of the Science on “Highly” Processed Food Intake and Body Weight.
- A Fancy Name for Junk Food: Does the war on “ultra-processed foods” make any sense? - By Gary Taubes."
- Inappropriate Analyses Make Continuous Glucose Monitoring Appear Imprecise.
- Ketogenic Diet Prevents Obesity-Associated Pancreatic Cancer Independent of Weight Loss and Induces Pancreatic Metabolic Reprogramming [in Mice].
- Food Noise: A Real Phenomenon Deserving of Being Treated.
Headline vs Study
- Headline: Scientists Discover What Triggers Belly Fat as We Age.
- Study: Adipogenesis Contributes to Age-Related Visceral Adipose Tissue Accumulation... In Mice.
Contrary or Null Findings
- RCT: "Contrary to common expectations that cold exposure suppresses anabolic signaling, the combination of traditional resistance training and cold-water immersion elicited a synergistic molecular response, optimally stimulating both hypertrophic and angiogenic pathways, and even surpassing the high-intensity rest-pause protocol."
- RCT: "An 8-week TRE [time restricted eating] intervention in young women with hidden obesity reduced body mass and BMI but also decreased total lean mass, potentially compromising metabolic health, with no statistically significant changes in total body fat or regional fat distribution."
- "Contrary to the hypothesis of this thesis and existing evidence, the prevalence of MetS and Hypertension was equally high in both rural and urban populations signifying shared risk factors between the two sites."
- "Contrary to conventional assumptions of uniformly negative impacts, a path undulation within the range of 1.6 - 1.8 m promotes walking among older adults."
- Thesis: “Healthier Lifestyle Behaviors Did Not Modify (Attenuate) the High Mortality Risks Observed with Greater Biologic Aging, Which Is Contrary to Our Study Hypothesis.”
- "Contrary to expectations of reduced feeding efficiency under osmotic stress, crabs in the lowest experimental salinity (2 ppt) exhibited the shortest handling times and highest feeding rates, more than doubling the prey consumption rates observed in the moderate salinity of 6 ppt. Female crabs also demonstrated higher attack rates, shorter handling times, and greater overall prey consumption than males, likely reflecting increased energetic demands during reproduction."
- Meta-Analysis of RCTs: "Probiotics did not significantly affect weight loss, metabolic parameters, or inflammatory markers."
- RCT: "Based on these results a single session of high-velocity low-amplitude manipulations targeting ankle DF-ROM does not significantly improve 1RM back squat strength compared to sham, and does not influence short-term ankle DF-ROM."
Basic
- Resveratrol Alleviates High-Fat Diet-Induced Obesity and Is Associated with Activation of β3-AR/AMPKα-Related Thermogenic Signaling.
- Circadian and Metabolic Effects of Light-Phase Time-Restricted Feeding with a Western-Style Diet in Young Female Rats.
- Maternal Butyrate Administration Ameliorates Fetal Fatty Liver and Maternal Metabolic Alterations Related to Maternal Obesity.
- Twf1 Regulates Adipocyte Proliferation and Differentiation Through Yap Nucleus Accumulation.
- Resistant Starch Supplementation Modulates Gut Microbiota, Short-Chain Fatty Acids, and Markers of Gut Barrier Integrity in Estrogen-Deficient Mice.
Scientific Rigor & Scholarly Dialogue
- Review: Advances, Challenges, and Future Directions in Precision Nutrition by Machine Learning-Based Prediction of Glycemic Responses to Foods.
- Evaluating the Reproducibility and Verifiability of Nutrition Research: A Case Study of Studies Assessing the Relationship between Potatoes and Colorectal Cancer.
Clinical
- Risk of Metabolic Dysfunction-Associated Steatotic Liver Disease and Hepatic Fibrosis: A Large-Scale Study from the Middle East.
- Long-Term Effect of Sweeteners and Sweetness Enhancers on Gene Expression Markers of Adipose Tissue Function, Adipocyte Morphology, and Metabolic Health: A SWEET Substudy.
- Effect of Methylphenidate on BMI in Children and Adolescents in Relation to Baseline Weight Status.
Children and Adolescents
- Review: Longitudinal Evaluation from Birth to Adolescence of Soy Protein–Based Infant Formula Compared with Cow Milk-Based Formula and Breastfeeding: A Comprehensive Summary of Findings.
- Capturing Infant and Child Growth Dynamics with P-Splines Mixed Effects Models.
Surgery
- A Technology-Based Intervention to Reduce Alcohol Use After Metabolic and Bariatric Surgery.
- Systematic Review: Comparable Survivorship and Patient-Reported Outcomes Following Unicompartmental Knee Arthroplasty in Patients with and without Obesity.
- Barbed Continuous Suture Reduces the Risk of Specimen Extraction Site Hernia in High-Risk Patients with Obesity.
- Differential Impact of Pre-Operative Tirzepatide Compared to Glucagon-Like-Peptide-1 Single Receptor Agonists on Outcomes of Spinal Fusion Surgery in Patients with Obesity.
- National Trends and Outcomes of Metabolic and Bariatric Surgery in Adolescents: Insights from the Israeli National Bariatric Surgery Registry.
- Incidence and Patterns of Anesthetic Complications During Bariatric Surgery.
- 30-Day Outcomes of Simultaneous Sleeve Gastrectomy and Kidney Transplantation.
- Surgery on Patients Taking Glucagon-Like Peptide-1 Receptor Agonists.
Drugs
- Smell and Taste Disturbances Among Glucagon-Like Peptide-1 Receptor Agonist Users.
- Review: Overview of Novel Mechanisms in Obesity Pharmacotherapy and Implications for Cardiovascular Disease.
- Effect of Icosapent Ethyl Treatment on Colorectal Tissue Marine Omega-3 Polyunsaturated Fatty Acid Levels Among Patients with a History of Adenoma: A Prospective, Single-Arm Clinical Trial.
Food & Diet
- Meta-Analysis: Does Consuming Ascorbate-Rich Fruits and Fruit Juices with Meals Improve Iron Bioavailability?
- RCT: Oat-Rich Low-Gluten Diet Modulates Plasma Short-Chain Fatty Acids Without Significant Changes in Fecal Microbiome or Inflammatory Markers.
Caloric and Dietary Restriction
- Prospective Association between Weight Variability and Subsequent Long-Term Weight Loss in the CALERIE Study.
- RCT: The Effects of Continuous vs. Intermittent Caloric Restriction on Fat Loss.
Exercise & Physical Activity
- Exercise Training Is Associated with Changes in Adipocyte Size and Lipid Metabolism in Older Women: Cross-Sectional and Longitudinal Study.
- Longitudinal and Cross-Sectional Evidence That Daily Resting and Activity Energy Expenditures are Independent in Humans.
Economics & Sociology
- Socioeconomic Differences in the Prevalence, Treatment and Control of Major Cardiometabolic Risk Factors by Sex: A Cross-Sectional Study of the UK Biobank.
- Impact of High BMI on Health State Utilities: A Time Trade-Off Study in the General Population of Japan.
- Sex Differences in the Socioeconomic Gradient of Latent Cardiometabolic Phenotypes in a Working-Age Population from the Balearic Islands (Spain): A Population-Based Analysis.
- Overweight/Obesity Clustering and Wealth Differentials Among Indigenous Households in Eastern India.
- Factors Associated with Obesity Among Female Workers in Small and Cottage Industries in Bangladesh: A Cross-Sectional Study.
Epidemiology
- Changes in Obesity and Waist Circumference in Children and Parents During the COVID-19 Pandemic.
- Dementia Risk by Metabolic Health and Obesity in Two Prospective Cohorts.
- Prevalence and Biopsychosocial Factors Associated with Overweight and Obesity in Adults with Type 1 Diabetes.
Psychology & Neuroscience
- Meta-Analysis: Effects of Mindfulness and Mindful Eating on Food Intake and Appetite.
- Cortical Thickness and Appetite Hormones in Adolescent Obesity and Binge Eating Disorder: A Comparative Study.
Differential Population Circumstances, Exposures, Outcomes, and Effects
Stigma
- The Case to Augment Healthcare Professional Training for the Treatment of Obesity by Integrating Cognitive Dissonance Interventions to Reduce Weight Stigma.
- Independent and Opposing Effects of Self-Complexity and Weight-Based Social Identity Threat on Well-Being Among Larger-Bodied People.
- Weight Stigma Exposure, Self-Perceived Weight and Weight Bias Internalisation Across Preconception, Pregnancy and Postpartum.
Policy Related
- The Validity and Utility of Nova and the Concept of Ultra-Processed Foods for Science and Policy.
- A Comprehensive and Standardized Dataset on School Feeding Activities Worldwide: The Global Survey of School Meal Programs.
- From Children to the Entire Population: Policy Lessons from a Decade of Successful Sodium Intake Reduction in South Korea.
- Grant Funding Program Supports Increasing School Meals.
- The New Orleans Healthy Default Beverage Policy and Beverage Ordering Among Children.
- State and Federal Policies and School Meal Participation: A Descriptive Analysis from Arizona.
Intergenerational Effects
- Parental BMI and Offspring Childhood Body Size and Eating Behaviour: A Structural Equation Modelling Analysis in the Norwegian Mother, Father and Child Cohort Study.
- Dietary Interventions Targeting Maternal Obesity: Intergenerational Effects, Mechanisms, and Translational Insights.
- Intergenerational Obesity Prevention Through Nanogenomic Targeting of Gestational Diabetes-Induced Epigenetic Programming.
Ecology, Evolution, & Energetics
- Mitochondrial Remodeling in Obesity: Mechanistic Links to Impaired Energy Metabolism and Therapeutic Perspectives.
- Cyclic Fasting Drives Metabolic and Physiological Changes in Drosophila melanogaster.
Methods
- Reassessing BMI Thresholds for Obesity: A Population-Based Study in Turkish Adults.
- Machine Learning-Based Prediction of Comprehensive Lipid Response to Dietary Interventions in Women with Overweight or Obesity.
Commentary
- Podcast: New Research on Muscle, Pregnancy, Menopause & Aging Strong: Dr. Christina Prevett.
- Unlocking the Food Matrix.
- Podcast: Muscle Mass Loss and Weight Loss Drugs: Overblown Fears or Justified Concerns?
- The Race to Build the Next Generation of Weight Loss Pills Is Heating Up.
- Is It Time to Stop Measuring Exercise by the Pound?
- Podcast: Dr. Andrew Koutnik | Ketogenic Diets and Athletic Performance | June 21, 2026 | Ep. 71.
- Ketone Esters May Help Preserve Muscle Mass and Strength for Semaglutide Users Without Affecting the Fat Loss Benefits of the Drug, Suggests Data from a Recent Study with Lab Mice.
- An Important New Data Source for Obesity Trends in England.
General
- The Senescence-Stiffening Loop: Extracellular Matrix Remodeling, Hypoperfusion, and Mitochondrial Dysfunction Drive Tissue Aging.
- Book: Bias! How Systemic Error Threatens Biomedical Research.
- After Menopause, Ovaries May Transform Into Organs with Immune Powers.
- Podcast: Nobody Tells You What GLP-1s Do to Your Sex Drive | GLS #213.
- Oo Oo, Ha Ha: Why Humans and Great Apes Giggle Alike When Tickled.
- Drivers of Academic Misconduct by Professors and Research Students Revealed.
- Foraging Success Influences Foraging Motivation in Ants.
- RNA Variants as Biological Indicators.