Featured

• Residential Segregation and Overweight/obesity Among African-American Adults: A Critical Review.
• Ghrelin Agonist Does Not Foster Insulin Resistance but Improves Cognition in an Alzheimer’s Disease Mouse Model.
• The 2015 US Dietary Guidelines: Lifting the Ban on Total Dietary Fat.

Headline vs Study

• Headline: Study Shows Red Wine Can Help Burn Body Fat, Prevent Obesity.
• Study: "Resveratrol induces brown-like adipocyte formation in white fat through activation of AMP-activated protein kinase (AMPK) α1" in mice.

Contrary or Null Findings

• Systematic Review: "Despite the Large Number of Studies, We Found Limited Evidence for Associations between Local Food Environments and Obesity."
• RCT: Daily Weight Monitoring Had No Harmful Effects, but Did Not Reduce Weight Gain in Healthy Weight and Overweight Young Adult Women.
• Contrary to Hypotheses, Prenatal Non-DEHP Phthalate Exposures Were Associated with Lower BMI Z-score, Waist Circumference and Fat Mass in Boys During Early Childhood.
• RCT: “In Contrast to Conventional Nutritional Counseling in Diabetes, Which is Largely Restrictive and Focuses on ‘how Much’ and ‘what Not to Eat,’ This Pilot Study Suggests That Improvement in Glycemia May Be Achieved By Optimal Timing of Carbohydrate Ingestion During a Meal.”

Basic

• Effects of High-fat Diet Exposure on Learning & Memory.
• Analysis of the Human Proteome in Subcutaneous and Visceral Fat Depots. (pdf)
• Administration of 17β-estradiol to Ovariectomized Obese Female Mice Reverses Obesity-hypertension Through an ACE2-dependent Mechanism.
• Protection From Diet-induced Obesity and Insulin Resistance in Mice Lacking CCL19-CCR7 Signaling.

Scientific Rigor & Scholarly Dialogue

• Letter Critiquing Methods of "Systematic Review and Meta-Analysis on Obesity—Mortality Association and Age."
• Misrepresentation of Carbohydrate for Exercise: ‘It is Time to Bust the Myth of Physical Inactivity and Obesity: You Cannot Outrun a Bad Diet’.
• Physical Activity and Obesity Editorial: Is Exercise Pointless or Was It a Pointless Exercise?

Clinical

• Reach of Effective, Nationally-Available, Low-Cost, Nonprofit Weight Loss Program in Medically Underserved Areas.
• RCT: Energy Balance 4 Kids with Play.
• Life-course BMI Trajectories and Blood Pressure in Mid Life in Two British Birth Cohorts: Stronger Associations in the Later-born Generation.
• Altered Characteristics of Balance Control in Obese Older Adults.
• NIH Study Demonstrates Metabolism Affects Ease of Weight Loss.
• A Systemic Review and Meta-analysis of RCTs of the Impact of Sleep Duration on Adiposity and Components of Energy Balance.
• Daily Weigh-ins, Tracking Could Improve Weight Loss Success.

Surgery

• The Role of Bile Acids in Reducing the Metabolic Complications of Obesity After Bariatric Surgery: A Systematic Review.
• The Changing Bariatric Surgery Landscape in the USA.

Drugs

• RCT: Six-month Efficacy and Safety of Amfepramone in Obese Mexican Patients.
• Orally Active Ghrelin Receptor Inverse Agonists and Their Actions on a Rat Obesity Model.
• Drug Improves Cognition in Alzheimer’s Disease-Mouse Model in Spite of Diet.

Food & Diet

• RCT: Consumption of Sucrose-sweetened Soft Drinks Increases Plasma Levels of Uric Acid in Overweight and Obese Subjects.
• Diets Rich in Fructose, Fat or Fructose and Fat Alter Intestinal Barrier Function and Lead to the Development of Non-alcoholic Fatty Liver Disease Over Time in Mice.
• RCT: Snack Purchasing is Healthier When the Cognitive Demands of Choice are Reduced.
• Order in Which Food is Eaten May Affect Type 2 Diabetics' Blood Sugar.
• RCT: Effect of Allowing Choice of Diet on Weight Loss.

Caloric Restriction

• The Effects of Graded Levels of Calorie Restriction: II. Impact. (pdf)
• Long Term Consequences on Spatial Learning-memory of Low-calorie Diet During Adolescence in Female Rats; Hippocampal and Prefrontal Cortex BDNF Level, Expression of NeuN and Cell Proliferation in Dentate Gyrus.
• A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.
• The Effects of Age and Dietary Restriction on the Tissue-specific Metabolome of Drosophila.
• The Effects of Graded Levels of Calorie Restriction: I. Impact of Short Term Calorie and Protein Restriction on Body Composition in the C57BL/6 Mouse.
• Nuclear Magnetic Resonance-Based Blood Metabolic Profiles of Rats Exposed to Short-Term Caloric Restriction.

Exercise & Physical Activity

• Understanding the Cellular and Molecular Mechanisms of Physical Activity-Induced Health Benefits.
• High-intensity Interval Training for Improving Health-related Fitness in Adolescents: A Systematic Review and Meta-Analysis.
• Patterns of Physical Activity Among Older Adults in New York City: A Latent Class Approach.
• Effects of Early-onset Voluntary Exercise on Adult Physical Activity and Associated Phenotypes in Mice.

Economics & Sociology

• The Impact of Neighborhood Socioeconomic Position on Prevalence of Diabetes and Prediabetes in Older Latinos: The Sacramento Area Latino Study on Aging.
• Cost Effectiveness of Childhood Obesity Interventions: Evidence and Methods for CHOICES.
• Biological Health Risks and Economic Development. (pdf)

Epidemiology

• Genetically Predicted BMI and Alzheimer's Disease–related Phenotypes in Three Large Samples: Mendelian Randomization Analyses.
• Behavioral and Environmental Modification of the Genetic Influence on BMI: A Twin Study.
• Diet Patterns and Risk of Sepsis in Community-dwelling Adults: A Cohort Study.
• Marriage and Parenthood in Relation to Obesogenic Neighborhood Trajectories: The CARDIA Study.
• Prevalence of Overweight and Obesity in the United States, 2007-2012.

Psychology

• The Influence of HOPE VI Neighborhood Revitalization on Neighborhood-Based Physical Activity: A Mixed-Methods Approach.
• Greater Perceived Ability to Form Vivid Mental Images in Individuals with High Compared to Low BMI.

Stigma

• Exploring the Links Between Culture, Locus of Control and Self-Compassion and Their Roles in the Formation of Weight Stigmatization.
• What Makes Them More Vulnerable Than Others? Obesity, Negative Emotions, and Peer Bullying Victimization.
• Experiencing Weight Bias in an Unjust World: Impact on Exercise and Internalization.

Policy Related

• Gap Between Evidence and Patient Access: Policy Implications for Bariatric and Metabolic Surgery in the Treatment of Obesity and Its Complications.
• With the Benefit of Foresight: Obesity, Complexity and Joined-up Government.
• Companies Take a Broader View of Employee Wellness Programs.

Intergenerational Effects

• Preconceptional Obesity and Fetal Outcomes: Transdisciplinary Evidence for Obesity’s Effects on Fertility.
• Increased Palatable Food Intake and Response to Food Cues in Intrauterine Growth-restricted Rats are Related to Tyrosine Hydroxylase Content in the Orbitofrontal Cortex and Nucleus Accumbens.

Ecology, Evolution, & Energetics

• A Test of Energetic Trade-offs Between Growth and Immune Function in Watersnakes.
• The Energetic Value of Land-Based Foods in Western Hudson Bay and Their Potential to Alleviate Energy Deficits of Starving Adult Male Polar Bears.
• Distance to Faraway Double-star System Measured Using X-rays.

Methods

• Analysis of the Network Effects on Obesity Epidemic.
• Fat Quantification in Skeletal Muscle Using Multigradient-echo Imaging: Comparison of Fat and Water References.
• A DXA Whole Body Composition Cross-Calibration Experience: Evaluation with Humans, Spine, and Whole Body Phantoms.
• Development of the Barriers to Physical Activity Questionnaire for People with Mobility Impairments.
• Bias in Estimating the Cross-sectional Smoking, Alcohol, Obesity and Diabetes Associations with Moderate-severe Periodontitis in the Atherosclerosis Risk in Communities Study: Comparison of Full Versus Partial Mouth Estimates.
• Spatial Modelling of Type II Diabetes Outcomes: A Systematic Review of Approaches Used.
• Broadening Public Participation in Systematic Reviews: A Case Example Involving Young People in Two Configurative Reviews.

Commentary

• The Real Reason That People are Obese.
• Obesity Rates: How Do You Spell Up?
• Nutrients, Nutritionism, and Historical Nuttiness.
• Calorie Counting Revisited: Why Trying to Cut Food Calories Could Make Us Fat and Sick.
• How Did We Get All This Obesity?
• Three Sources of Obesity Confusion.
• Fatter but Fitter.
• Debunk the Junk. (pdf)
• Healthy Dads, Healthy Kids.
• Listen Doctor, the Patient Just Might Be Right.
• A Point of Reference: Weight and the Concept of Set Point.
• Michelle Obama Vows More of Let’s Move.
• Normal Regulation of Human Body Weight.
• Body Composition and the Obesity Paradox in Coronary Heart Disease: Can Heavier Really Be Healthier?
• Assessing the Population Impact of Published Intervention Studies.

General

• How Dividing Cells End Up the Same Size.
• If It is Published in the Peer-reviewed Literature, It Must Be True?
• The Pressure to Publish High-profile Papers May Not Be Linked to Research Misconduct, a New Study Has Found.
• How High-tech Treatments Add Hope, and Cost, to Keeping a Sick Pet Alive.

Video & Audio

• Audio: Not All Cooking Oils are Created Equal.

Announcements

• UAB Names National Leader in Myocardial Bioenergetics New Chair of Biomedical Engineering.
• Interview with TOS Fellow – Peter T. Katzmarzyk, PhD, FTOS.
• Access to the American Diabetes Association-funded Research Database.