06/19/26
Featured
- Eleventh and 12th-Grade Students from an Economically Disadvantaged Charter School Express High Interest in Food/Cooking Education.
- Modeling the Circadian Dynamics of Resting Energy Expenditure for the Built Environment.
- Time-Restricted Feeding Extends Healthspan in Both Sexes and Lifespan in Male C57BL/6 J Mice.
- Definitions of Arginine Availability: A Critical Metabolic Marker of Physiological Processes.
Headline vs Study
- Headline: What You Eat May Be Shaping Your Mental Health - Especially If You're a Woman.
- Study: Self-Reported Dietary Inflammatory Index Is Associated with Reported Depressive Symptoms in Men and Women, with No Formal Test to See Whether It Is Especially for Women.
Contrary or Null Findings
- "Omega-3 supplementation may be associated with accelerated cognitive decline in older adults... These findings challenge the prevailing view of omega-3 as uniformly beneficial and highlight the need for a cautious reassessment of its widespread use for cognitive protection."
- "...unlike in C. elegans, WWP1 is not required for CR-induced longevity in mammals..."
- RCT: "The linear mixed-effects models using period-level change scores showed no statistically significant treatment effects for steps, sleep time, sedentary time, lightly active time, or active time" in "Feasibility of remotely delivered Tai Chi on older adults’ 24-hour movement behaviors."
- RCT: "...no significant between-group differences were detected..." in "The Effect of Low Glycemic Load Diet on Central Obesity and Lipid Related Metabolic Abnormalities in T2DM Patients Is Comparable to That of Energy-Restricted Diet..."
- RCT: No Significant Between-Group "Effects of Continuous vs. Intermittent Caloric Restriction on Fat Loss."
- RCT: "Sakurajima radish does not appear to improve endothelial function in patients with MetS within the constraints of this short-term crossover design."
- RCT: "The intervention improved participants' nutrition-related KAP [knowledge, attitude, and practice] scores but did not increase the intake of immune-enhancing nutrients, except for vitamin E."
- RCT: "The primary outcome, subjective fatigue assessed using the web-based daily log, was not significantly different between groups during the summer study period" in "Combined NY1301 and DDMP on Sleep and Autonomic Function in Summer".
Basic
- Nitrate-Sialin2 Axis Couples ER-Mitochondrial Calcium Signaling with Fatty Acid Metabolism to Drive White Adipose Browning.
- Independent and Synergistic Effects of Maternal and Paternal Obesogenic Diets on Offspring Early-Life Outcomes in the Rat.
- Genome-Wide DNA Methylation Changes Induced by High-Fat Diet and Methyl Donor Supplementation in Female Lupus Models.
- Dietary Omega-6 Lipids Promote Post-Injury Aberrant Bone Formation in Obesity.
- Time-Restricted Feeding Counters Brown Adipose Tissue Whitening and Inflammation in Obese Mice Under Chronic Light Exposure.
Scientific Rigor & Scholarly Dialogue
- BITESIZE: Omega-3 Supplements and Cognitive Decline? Here’s the Full Story.
- Perspective: Interpreting Ultra-Processed Food Trial Evidence: Evidentiary Limits, Reporting Practices, and Policy Relevance.
- Believing Is Seeing: Effects of Food Labeling in Chile.
- Review: Concerns Regarding the Standard Deviation of Individual Responses for Assessing Treatment Response Heterogeneity | Journal of Applied Physiology.
- Letter: Misconceptions About Variance Comparisons for Exploring the Presence of Treatment Response Heterogeneity in Randomized Controlled Trials | Journal of Applied Physiology.
- Reply to Atkinson et al. | Journal of Applied Physiology.
Clinical
- RCT: Time-Restricted Eating Promotes Weight Loss and Favorable Changes in Adipose in Obesity.
- RCT: Multidimensional Effects of Personalized Exercise Intervention in Type 2 Diabetes.
- Meta-Analysis: Cardiovascular Outcomes of Glucagon-Like Peptide-1 Receptor Agonists in Patients Without Obesity.
Children and Adolescents
- Disparities of Children’s Obesogenic Environments in Louisiana.
- Observed Mealtime Interactions, Meal Healthfulness, and Childhood Obesity Among Low-Income Families.
- Meal Replacement Therapy for Metabolic Dysfunction-Associated Steatotic Liver Disease in Adolescents with Severe Obesity.
- Review: Childhood Obesity: Epidemiology, Risk Factors, Prevention, and Emerging Treatment Strategies.
- Parental Communication with Children around Obesity Management Medications, Weight Loss, and Health Behavior Change.
- Prevalence of Preclinical and Clinical Obesity Among US Children and Adolescents Aged 5 to 18 Years: NHANES 2017-2023.
Surgery
- Global Variability in Children and Adolescent Metabolic Bariatric Surgery Guidelines: A Worldwide IFSO Survey.
- Divergent Colorectal Cancer Risks Following Metabolic Bariatric Surgery: Anatomical Remodeling and the Genotoxic Microenvironment.
- Inguinal Hernia Repair Utilizing Laparoscopic Techniques in People with Obesity.
- Systematic Review: What Is Weight Loss After Bariatric Surgery Expressed in Percentage Total Weight Loss (%TWL)?
- Case report: Multilevel Endoscopic Thoracic Spine Surgery in a Patient with Obesity.
Drugs
- Physical Fitness with Exercise and GLP-1 Receptor Agonist Treatment Alone or Combined After Diet-Induced Weight Loss.
- RCT: Survodutide Once Weekly for the Treatment of Adults with Obesity.
- RCT: Treatment with 9-mg Mazdutide for Weight Reduction in Chinese Adults with Obesity.
- Zealand Pharma Announces Boehringer Ingelheim's Survodutide Phase III Trial in People Living with Obesity Showed Targeted 34% Visceral and 63% Liver Fat Reduction, While Minimizing Lean Mass Loss in Pre-Specified Analysis.
- Meta-Analysis: Placebo Response on the Weight Change and Its Influencing Factors in Overweight or Obesity with or Without Diabetes.
Food & Diet
- Review: Spices for Targeting the Gut Microbiome to Improve Cardiometabolic Health.
- Semaglutide-Induced Loss of Skeletal Muscle Mass Is Blunted by Co-Administration of Ketone Esters.
- Review: The Purpose of Food Processing and Ultra-Processed Food: The Potential, Pitfalls and Path Forward for Public Health.
- Meta-Analysis: "Higher adherence to the MD [Mediterranean diet] is associated with a reduced risk of all-cause mortality".
- Meta-Analysis: Impact of Tomatoes and Tomato-Derived Products on Obesity and Cardiometabolic Health.
- Meta-Analysis: Late Eating and Obesity.
Caloric and Dietary Restriction
- When Caloric Restriction and Exercise Join Forces: Counteracting the Detrimental Effects of Obesity on the Musculoskeletal System.
- Trace Element Dynamics Following Low-Calorie Formula Diet and Their Association with Glycaemic Traits.
- RCT: Very Low Calorie Diet Versus Conventional Energy-Restricted Diet for Weight Loss Before Bariatric Surgery.
- Review: Caloric Restriction Rejuvenates Aged Adult Stem Cells: From Mechanisms to Interventions.
Exercise & Physical Activity
- RCT: Myosin Light Chain Proteins Cooperatively Promote Sarcomere Growth in Fast-Twitch Muscle.
- RCT: Prunes Preserve Cortical Density and Estimated Strength of the Tibia in Postmenopausal Women.
- Exercise Attenuates Obesity-Related Cognitive and Sleep-Circadian Dysfunctions by Attenuating Neuroinflammation Via JAK/STAT in Sex and Age Specific Manner.
- Systematic Review: Digital Health Interventions for Physical Activity in Children and Adolescents with Obesity.
- Longitudinal Associations between Physical Activity-Sedentary Time Balance and Internalizing/Externalizing Problems in Children.
Economics & Sociology
- GLP-1 Therapy and the Reshaping of Socioeconomic Gradients in Health.
- Systematic Review: Obesity, Employment, and Economic Productivity in Europe.
Epidemiology
- Associations between Screen Time and Dietary Intake Among Early Adolescents: A Prospective Cohort Study.
- Early-Onset Obesity and Heart Failure Burden Independent of Cardiometabolic Risk Factors.
- Association between Metabolic Heterogeneity of Obesity and Biological Aging Among Adults: A Population-Based Study.
- Meta-Analysis: Obesity Is Associated with Suppressed Bone Turnover.
Psychology & Neuroscience
- Systematic Review: Effectiveness of Internet-Delivered Cognitive Behavioural Therapy in Improving Weight-Loss and Psychosocial Well-Being Among Adults with High BMI.
- Anti-Obesity Medications and Cognitive Disorder Risk: A Discrepancy between RCTs and Real-World Evidence.
- Depression Meets Obesity: Co-occurrence Patterns, Temporal Trends and Socioeconomic Correlates Across 199 Countries and Territories.
- Commentary: Your Brain on a GLP-1: What We Know About the Mental Side.
Differential Population Circumstances, Exposures, Outcomes, and Effects
- A Cross-Sectional Investigation of Relationships between Food Pleasure and Worry, Eating Behaviors, and Cultural Attributes Among Mexican American Adults.
- Preprint: Twenty-Year Trends in Adolescent Overweight and Obesity and Socioeconomic Inequalities.
- Food Insecurity, Dietary Quality, and Cardiovascular Risk Among Early Childhood Cancer Survivors.
- Associations between Race, Healthcare Coverage, Adiposity, and Cardiometabolic Risk Among Underserved U.S. Adolescents.
Ethics
Stigma
- Psychometric Validation of the Weight and Emotions Scale (WES) in Adults with Obesity or Overweight.
- Commentary: Obesity Stigma: Is Art History the Fix?
- Internalized Weight Stigma and Obesity-Related Quality of Life in Adults with Obesity or Overweight.
Policy Related
- From a Policy Perspective, Is Sugar the New Tobacco?
- Commentary: New Federal Food Policies Will Affect Food Labeling, Reformulation, and Healthfulness.
- Integrated Food Policy and Child Obesity.
- Commentary: A Framework for Developing Intake and Use Guidance for Dietary Supplement Bioactives.
- Evidence-Informed Guidance for the Clinical Use of Oral Semaglutide in Obesity Management.
Intergenerational Effects
- Genetic and Environmental Influences on Educational Disparities in Adult Weight Change: An Individual-Based Pooled Analysis of 11 Twin Cohorts.
- Long-Term Effects of Exercise During Pregnancy on the Metabolic Health of Mothers with Overweight/Obesity and Their Offspring.
Ecology, Evolution, & Energetics
- Energy Requirements: The Case for the Factorial Model.
- Renal Gluconeogenesis: A Key Metabolic Hub in Health and Kidney Disease.
Methods
- Systematic Review: How Have Researchers Estimated the Impact of Excess Weight on Mortality?
- Systematic Review: Validated Food Quantification Aids for Dietary Assessment.
- Temporal External Validation of a Customized Fetal BMI Percentile Model for Neonatal Nutritional Status Assessment.
- Assessment of Body Composition in Severe Obesity: Agreement between Multifrequency Bioelectrical Impedance Analysis and DXA and Contribution of Raw Impedance Data.
Commentary
- Podcast: Dominic D’Agostino Discusses Advances in Ketogenic Metabolic Therapy and Hyperbaric Oxygen Therapy.
- Podcast: Brain Lipidology: Understanding APOE, Cholesterol Homeostasis, Alzheimer’s Disease Risk, and the Effects of Lipid-Lowering Therapies on Brain Health | Tom Dayspring, M.D.
- "Elecoglipron, a novel oral GLP-1 receptor agonist (RA), led to significant reductions in A1c and moderate reductions in body weight in people with type 2 diabetes (T2D), according to the results of the phase 2b SOLSTICE trial."
- Podcast: Female Training, Hormones & Nutrition: Fact Vs. Fiction | Dr. Lauren Colenso-Semple.
- Time-Restricted Feeding Puts Mouse Healthspan on the Clock.
- Eos SENOLYTIX Presents Best-In-Class Preclinical Body Composition Data Highlighting Unique Muscle Mass Gains with MitoXcel™ Geropeptide PTC-2105 at the Sachs 2nd Annual Obesity & Cardiometabolic Innovation Forum.
- Implicit Bias Inferring Causality for Obesity Medicines.
- Interaction of Physical Activity and Gut-Brain Axis: Relevance for Obesity.
General
- Podcast: Public Health Misinformation & Communication: How to Build Trust for Behavior Change - Dr. Jessica Steier.
- First in Situ Observations of the Goblin Shark Mitsukurina owstoni.
- Podcast: Derisking Phase II Clinical Trials in HF.
- Ameliorating Calcium Homeostasis Improves Longevity and Healthspan in Progeroid and Naturally Aged Mice.
- P21-Senescent Cells Drive Pancreatic Islet Dysfunction Through Targetable Paracrine Signaling in Type 2 Diabetes.
- Revealed: How Venus Flytraps Snap Shut with Astonishing Speed.
- Podcast: What’s the Future of Gene Editing?
- Ferroptosis Susceptibility in Hippocampal Neural Precursor Cells Influences Neurogenesis and Memory Across Aging.
- Humans Outperform AI at This Highly Rigorous Mathematics Test.
Video & Audio
- Podcast: Why Amylin May Be the Most Important Weight Loss Hormone You've Never Heard Of.
- Podcast: Public Health Equity | Stats + Stories Episode 388.
- Exploring the Benefits of Creatine for Aging Adults Grappling with Loss of Muscle Mass.