Featured

• Scarcity Mindset Alters Neural Processing Underlying Consumer Decision Making.
• RCT: The Consequences of Foster Care Versus Institutional Care in Early Childhood on Adolescent Cardiometabolic and Immune Markers.
• Social Transmission of Food Safety Depends on Synaptic Plasticity in the Prefrontal Cortex.
• Targeting Glucose Metabolism to Enhance Immunotherapy: Emerging Evidence on Intermittent Fasting and Calorie Restriction Mimetics.

Headline vs Study

• Headline: Study finds avocados curb appetite and help with weight loss.
• Study: This was a 6-hour RCT demonstrating effects on short-term reports of hunger – neither effects on actual food intake nor on body weight were studied.

Contrary or Null Findings

• RCT: Videogames that Encourage Healthy Behavior Did Not Alter Fasting Insulin or Other Diabetes Risks in Children.
• Lack of Improvement of Sperm Characteristics in Obese Males After Obesity Surgery Despite the Beneficial Changes Observed in Reproductive Hormones.
• RCT: Limited "effects on inflammatory and glycemia-related markers of a whole-grain pasta containing barley β-glucans and Bacillus coagulans BC30, 6086 in healthy overweight or obese volunteers."
• RCT: The Degree of Aminoacidemia After Dairy Protein Ingestion Does Not Modulate the Postexercise Anabolic Response in Young Men.
• "In our comparative cohort study of preterm infants with a gestational age of 30–33 weeks, we found no advantage to routine use of probiotics."
• "Contrary to previous research, this data suggests that men who exercise at high volume will not experience negative outcomes to their sexual function..."
• RCT: No evidence that "a planning competence training (Planungskompetenztraining, PKT) can support participants of a medical rehabilitation program to foster lifestyle change."
• "...the hypothesis was not confirmed, since the high-saturated-fat diet-induced obese rats did not present cardiac dysfunction or impaired intracellular Ca2+ handling proteins."
• "Obesity-related cancer risks appear not to be offset or eliminated by high levels of physical activity or fitness."
• RCT: No Effect of Glucomannan on Body Weight Reduction in Children and Adolescents with Overweight and Obesity.
• RCT: "Among persons at high risk for type 2 diabetes not selected for vitamin D insufficiency, vitamin D3 supplementation at a dose of 4000 IU per day did not result in a significantly lower risk of diabetes than placebo."

Scientific Rigor & Scholarly Dialogue

• Replacement of Dropouts May Bias Results: Comment on “The Effect of Green Tea Ointment on Episiotomy Pain and Wound Healing in Primiparous Women: A Randomized, Double‐blind, Placebo‐controlled Clinical Trial”.
• Error in Statistical Code in Cluster Randomized Trial on the Effect of a Breakfast in the Classroom Initiative on Obesity in Urban, School-aged Children.
• Have We Really Found the Limit of Human Endurance?
• After Outcry, USDA Will No Longer Require Scientists to Label Research ‘preliminary’.
• “Permeable to Bad Science:” Journal Retracts Paper Hailed By Proponents of Homeopathy.

Basic

• A PRDM16-Driven Metabolic Signal From Adipocytes Regulates Precursor Cell Fate.
• Cyanidin-3-O-Galactoside-Enriched Aronia Melanocarpa Extract Attenuates Weight Gain and Adipogenic Pathways in High-Fat Diet-Induced Obese C57BL/6 Mice.
• Clcn3 Deficiency Ameliorates High-Fat Diet-Induced Obesity and Adipose Tissue Macrophage Inflammation in Mice.
• Excessive Visceral Adiposity Induced By a High-Fat Diet is Associated with Increased Fibrosis and Decreased Immune Cellularity of the Mesenteric Lymph Node in Mice.
• Estradiol and NADPH Oxidase Crosstalk Regulates Responses to High Fat Feeding in Female Mice.
• GABA-Stimulated Adipose-Derived Stem Cells Suppress Subcutaneous Adipose Inflammation in Obesity.
• GDF15 Mediates Adiposity Resistance Through Actions on GFRAL Neurons in the Hindbrain AP/NTS.
• Decelerating Ageing and Biological Clocks By Autophagy.

Clinical

• Long-Term Effects of a Novel Continuous Remote Care Intervention Including Nutritional Ketosis for the Management of Type 2 Diabetes: 2-Year Non-randomized Clinical Trial.
• RCT: Postprandial Levels of GLP-1, GIP and Glucagon After 2 Years of Weight Loss with a Paleolithic Diet in Healthy Obese Women.
• RCT: A Lifestyle Program Targeting Women with Obesity and Infertility Improves Their Fertility.

Children and Adolescents

• Do Country-level Environmental Factors Explain Cross-national Variation in Adolescent Physical Activity? A Multilevel Study in 29 European Countries.
• RCT: Efficacy of a Home-Based Parent Training-Focused Weight Management Intervention for Preschool Children.

Surgery

• Donor Metabolic Characteristics Drive Effects of Faecal Microbiota Transplantation on Recipient Insulin Sensitivity, Energy Expenditure and Intestinal Transit Time.
• Gastro-Intestinal Tract Cancers Following Bariatric Surgery: A Review.
• Comparative Study of Resting Metabolic Rate and Plasma Amino Acid Profile in Patients Who Underwent Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy: 6-Month Follow-up Study.

Drugs

• RCT: Postprandial Hypoglycaemia After Roux‐en‐Y Gastric Bypass and the Effects of Acarbose, Sitagliptin, Verapamil, Liraglutide and Pasireotide.
• RCT: Assessment of Compounded Transdermal Mirtazapine as an Appetite Stimulant in Cats with Chronic Kidney Disease.
• Lack of Durable Improvements in β-Cell Function Following Withdrawal of Pharmacological Interventions in Adults with Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes.
• RCT: Oral Semaglutide Versus Subcutaneous Liraglutide and Placebo in Type 2 Diabetes (PIONEER 4).

Food & Diet

• Capsaicin and Genistein Override the Action of Obestatin to Decrease Lipid Accumulation in 3T3-L1 Cells.
• Investigating the Effect of Sex and Ketosis on Weight-loss-induced Changes in Appetite.
• Different Acute Effects of Fructose and Glucose Administration on Hepatic Fat Content.
• RCT: The Effect of High Compared with Low Dairy Consumption on Glucose Metabolism, Insulin Sensitivity, and Metabolic Flexibility in Overweight Adults.
• RCT: High-protein Feeding Induces De Novo Lipogenesis in Healthy Humans.
• Animal-based and Plant-based Protein-rich Foods and Cardiovascular Health: A Complex Conundrum.
• RCT: Findings "do not provide evidence for choosing white over red meat for reducing CVD risk."
• Plant- and Animal-protein Diets in Relation to Sociodemographic Drivers, Quality, and Cost.
• Fiber Intake Predicts Weight Loss and Dietary Adherence in Adults Consuming Calorie-Restricted Diets.
• Meta-analysis: 46 Studies Identified By the FDA Demonstrates that Soy Protein Decreases Circulating LDL and Total Cholesterol Concentrations in Adults.

Caloric Restriction

• Methionine Restriction Delays Senescence and Suppresses the Senescence-associated Secretory Phenotype in the Kidney Through Endogenous Hydrogen Sulfide.
• A Novel Nutritional Supplement Prevents Muscle Loss and Accelerates Muscle Mass Recovery in Caloric-restricted Mice.
• Early Time-Restricted Feeding Improves 24-Hour Glucose Levels and A
  Ects Markers of the Circadian Clock, Aging, and Autophagy in Humans.

Exercise & Physical Activity

• Ready to Move: A Unique University Worksite Wellness Initiative.
• Exercise Trials for Blood Pressure Control: Keeping It Real.
• Neighbourhood Built Environment and Physical Function Among Mid-to-older Aged Adults: A Systematic Review.

Economics & Sociology

• The Price of Ultra-processed Foods and Beverages and Adult Body Weight: Evidence From U.S. Veterans.
• Socioeconomic Inequalities in Childhood-to-adulthood BMI Tracking in Three British Birth Cohorts.
• Examining Cumulative Inequality in the Association Between Childhood SES and BMI From Midlife to Old Age.
• BMI in Religious Contexts: Exploring the Multilevel Influences of Religion.

Epidemiology

• "Among individuals with MI, those that have engaged in any light or moderate physical activity were more likely to survive their MI."
• The Role of Country of Birth, and Genetic and Self-identified Ancestry, in Obesity Susceptibility Among African and Hispanic Americans.
• Association of Exposure to Artificial Light at Night While Sleeping with Risk of Obesity in Women.
• Clinical Manifestations and Factors Associated with Osteosarcopenic Obesity Syndrome: A Cross-Sectional Study in Koreans with Obesity.
• Cross-sectional and Prospective Associations of Actigraphy-Assessed Sleep Regularity with Metabolic Abnormalities.
• Tantalizing Data and Ample Buzz for Personalized Nutrition.

Psychology & Neuroscience

• Precision Medicine Analysis of a Behavioral Counseling Strategy to Improve Adherence to Diabetes Self-management Among Youth.
• Review: Temperament in Obesity-related Research: Concepts, Challenges, and Considerations for Future Research.
• Lived Experience of Obese People Who Feel that They are Addicted to Food (PDF).
• Longitudinal Preliminary Study of Addiction-Like Responses to Food and Alcohol Consumption Among Individuals Undergoing Weight Loss Surgery.
• Do Emotions Cause Eating? The Role of Previous Experiences and Social Context in Emotional Eating.

Equity and Disparities

• Does the Ethnic Density Effect Extend to Obesity? A Cross-sectional Study of 415 166 Adults in East London.
• Obesity and Disparities in Human Papillomavirus Vaccination for U.S. Adolescent Girls and Young Women.
• Effects of Economic Inequality on Obesity.

Stigma

• Weight Bias in Radiology Resident Selection.
• The Role of Weight Stigma in Parental Weight Talk.
• Implications of Differing Attitudes and Experiences Between Providers and Persons with Obesity.
• Addressing Internalized Weight Bias and Changing Damaged Identifies for People Living with Obesity.
• Perceived Weight Discrimination Mediates the Prospective Association Between Obesity and Physiological Dysregulation.
• How Doctors Can Stop Stigmatizing — and Start Helping — Kids with Obesity.

Policy Related

• Insights on the Influence of Sugar Taxes on Obesity Prevention Efforts.
• USDA Launches New School Nutrition Training Website.
• Executive Order on Modernizing the Regulatory Framework for Agricultural Biotechnology Products.

Intergenerational Effects

• Maternal, but Not Paternal or Grandparental, Caffeine Intake is Associated with Childhood Obesity and Adiposity.
• Association of Infant Feeding Patterns with Taste Preferences in European Children and Adolescents: A Retrospective Latent Profile Analysis.
• Maternal and Offspring Genetic Risk of Type 2 Diabetes and Offspring Birthweight Among African Ancestry Populations.
• The Effect of Maternal Dietary Habits During Pregnancy on Neonate Leptin Methylation Patterns and Gestational Age (PDF).
• Time-restricted Feeding Reduces High-fat Diet Associated Placental Inflammation and Limits Adverse Effects on Fetal Organ Development.
• Maternal Dietary Glycemic and Insulinemic Indexes are Not Associated with Birth Outcomes or Childhood Adiposity at 5 Years of Age in an Irish Cohort Study.

Ecology, Evolution, & Energetics

• Evolution Of, and Via, Developmental Plasticity: Insights Through the Study of Scaling Relationships.
• About “spendthrift” and “thrifty” Phenotypes: Resistance and Susceptibility to Overeating Revisited.
• Elephants Have a Nose for Quantity.

Methods

• Obesity and Chemotherapy Administration: Between Empiric and Mathematic Method Review.
• Application of Stable Isotope Labels for Metabolomics in Studies in Fatty Liver Disease.

Commentary

• Diet is a Vital Sign.
• Associations of Dietary Cholesterol and Egg Consumption with Incident Cardiovascular Disease and Total Mortality.
• The History of the Bagel: A New York City Story By Way of Poland and the Lower East Side.
• Perspective: Should Exclusive Breastfeeding Still Be Recommended for 6 Months?
• Medical Misinformation and the Internet: A Call to Arms.
• Fighting for the Common Ground of Better Diet.
• The Humble Glycemic Index Marks Global Diabetes Risk.
• 5 Little-known Facts About Protein.
• Better Metadata Could Help Save the World!

General

• Functional Regulators of Bacterial Flagella.
• Monkeys Use Their 'eagle' Call to Warn Each Other About Drones.
• Definitions of Sex and Intimacy Among Gender and Sexual Minoritised Groups in Urban India.
• To What Extent is Blood a Reasonable Surrogate for Brain in Gene. Expression Studies: Estimation From Mouse Hippocampus and Spleen.
• Research Integrity is Much More than Misconduct.
• When Pigs Fly: Emotional Support Animals, Service Dogs and the Politics of Legitimacy Across Species Boundaries.
• Life Finds a Way: Parthenogenesis in Asian Water Dragons [with Video].
• The Early Origin of Feathers.
• Forensic Pollen Scientists are Helping the US Track Opioids.
• Small, Furry and Powerful: Are Mouse Lemurs the Next Big Thing in Genetics?

Video & Audio

• Podcast: Diego Rose on Environmental Sustainability and Our Food.
• Podcast: Rick Larrick on the Hidden Energy Cost of Our Food.
• Outdated Gender Stereotypes are Harming Science.

Announcements

• IU to Acquire Fastest University-owned AI Supercomputer.
• Web-computing Platform Was Created By IU Scientists to Support and Publish Reproducible Neuroscience Research.
• Training Program: Post-Doctoral Fellowship in Obesity Research.
• Training Program: AHA Strategically Focused Research Center– Obesity Network: Intergenerational Transmission of Obesity.
• Short Course: Causal Inference in Behavioral Obesity Research, Indiana University Bloomington (July 29-August 2, 2019).