Featured

• RCT: Point-of-Consumption Interventions to Promote Virtuous Food Choices of Tourists with Self-Benefit or Other-Benefit Appeals.
• Restoration of Energy Homeostasis by SIRT6 Extends Healthy Lifespan [in Mice].
• Diet-Induced Obesity Impairs Outcomes and Induces Multi-Factorial Deficiencies in Effector T Cell Responses Following Anti-CTLA-4 Combinatorial Immunotherapy in Renal Tumor-Bearing Mice.

Headline vs Study

• Headline: Teens May See Increased Torso Fat but Better Cholesterol with Tivicay.
• Pre-Post Study: 12 Month Body Fat Distribution and Metabolic Changes (Not Necessarily Effects) in 13 Adolescents Living with HIV Switched to an Antiretroviral Regimen Containing Dolutegravir.

Contrary or Null Findings

• RCT: No Differential Effects of Synbiotic Supplementation vs Placebo on Serum Anti-Inflammatory Factors in the Survivors of Breast Cancer with Lymphedema Following a Low Calorie Diet.
• RCT: No Apparent Moderating Effects of Four Genetic Variations on Changes in Physical Activity Level and Cardiorespiratory Fitness in Response to a Life-Style Intervention.
• RCT: "Contrary to hypotheses, there were no significant differences in body satisfaction, shame, or future negative body talk likelihood across the four groups."
• "In overweight and obese pregnant women, we found no evidence that maternal dietary and/or lifestyle intervention during pregnancy modifies the risk of early childhood obesity."
• "In this 2-sample MR study, we did not observe evidence to support an association between 25OHD levels and COVID-19 susceptibility, severity, or hospitalization. Hence, vitamin D supplementation as a means of protecting against worsened COVID-19 outcomes is not supported by genetic evidence."
• "This MR study does not support a causal protective role to circulate vitamin C levels on various types of CVD events. In combination with previous RCT results, our findings suggest that vitamin C supplementation to increase circulating vitamin C levels may not help in CVD prevention."
• "Contrary to our hypothesis, and contrary to generally accepted findings on isolated muscle preparations, residual torque enhancement in voluntary and electrically evoked contractions does not seem to depend on the angular amplitude of the preceding eccentric contraction."
• "Contrary to control cells, adipocytes of obese hyperglycemic and hypertensive mice, growing on glucose, did not accumulate lipids and demonstrated hormonal resistance being non responsive to any hormone applied."

Basic

• Depletion of Prmt1 in Adipocytes Impairs Glucose Homeostasis in Diet-Induced Obesity.
• Stk24 Protects Against Obesity-Associated Metabolic Disorders by Disrupting the NLRP3 Inflammasome.
• The Gut Microbiota Regulates Hypothalamic Inflammation and Leptin Sensitivity in Western Diet-Fed Mice Via a GLP-1R-Dependent Mechanism.
• An Intronic Risk SNP Rs12454712 for Central Obesity Acts as an Allele-Specific Enhancer to Regulate BCL2 Expression.
• Differentially Expressed Genes and Enriched Signaling Pathways in the Adipose Tissue of People with Obesity.
• A Dietary Ketone Ester Mitigates Histological Outcomes of NAFLD and Fibrosis Markers in High-Fat Diet Fed Mice.

Scientific Rigor & Scholarly Dialogue

• Letter: Change to a Higher Carbohydrate Diet and Energy Expenditure Among Postmenopausal Women.
• Response: Reply to Prentice and Colleagues.
• Grading Nutrition Evidence: Where to Go from Here?

Clinical

• Meta-Analysis: Effect of Metformin on Lipid Profiles in Type 2 Diabetes Mellitus.
• Weight Loss and Usage of an Online Commercial Weight Loss Program Delivered in an Everyday Context: Five-Year Evaluation in a Community Cohort.
• Lipids Activate Skeletal Muscle Mitochondrial Fission and Quality Control Networks to Induce Insulin Resistance in Humans.
• Protocol: Behavioral Weight Loss in Emerging Adults: The Richmond Emerging Adults Choosing Health (REACH) Randomized Clinical Trial.
• Protocol: The Daily Self-Weighing for Obesity Management in Primary Care Study.

Children and Adolescents

• Meta-Analysis: Association of Very Preterm Birth or Very Low Birth Weight with Intelligence in Adulthood.
• Changes in Total Physical Activity, Leisure and Commuting in the Largest City in Latin America, 2003-2015.
• Restrained Eating in Lebanese Adolescents: Scale Validation and Correlates.
• Sex Differences in Changes in BMI and Blood Pressure in Chinese School-Aged Children During the COVID-19 Quarantine.
• Oxytocin Receptor Gene Polymorphism and Low Serum Oxytocin Level are Associated with Hyperphagia and Obesity in Adolescents.
• "Greater total screen-viewing time at age 2–3 years is associated with higher abdominal adiposity at age 4.5 years in boys."
• "Differences between [self-reported and device-based measured physical activity] were significantly smaller in younger children than in the older age groups."

Surgery

• Meta-Analysis: How Does Fat Mass Change in the First Year After Bariatric Surgery?
• Time Course of Metabolic, Neuroendocrine and Adipose Effects During 2 Years of Follow-Up After RYGB in Patients with T2D.
• Long-Term Results of One Anastomosis Gastric Bypass: A Single Center Experience with a Minimum Follow-Up of 10 Years.

Drugs

• RCT: Semaglutide 2·4 Mg Once a Week in Adults with Overweight or Obesity, and Type 2 Diabetes.
• Review: Pharmacogenomics of Medication-Induced Weight Gain and Antiobesity Medications.

Food & Diet

• RCT: Meal-Induced Inflammation: Postprandial Insights from the Personalised REsponses to DIetary Composition Trial (PREDICT) Study.
• RCT: Acute Consumption of a Shake Containing Cashew and Brazil Nuts Did Not Affect Appetite in Overweight Subjects.
• RCT: Acute Effects of Extruded Pulse Snacks on Glycemic Response, Insulin, Appetite, and Food Intake in Healthy Young Adults.
• Habitual Use of Fish Oil Supplements, Genetic Predisposition, and Risk of Fractures: A Large Population-Based Study.
• Trans-Palmitoleic Acid Reduces Adiposity Via Increased Lipolysis in a Rodent Model of Diet-Induced Obesity.
• Association of Aryl Hydrocarbon Receptor Serum Level and Gene Rs10247158 Polymorphism with Anthropometric, Biochemical Parameters and Food Consumption in Patients with Overweight/Obesity.

Caloric and Dietary Restriction

• RCT: Effect of Probiotic Supplementation Along with Calorie Restriction on Metabolic Endotoxemia, and Inflammation Markers in Coronary Artery Disease Patients.
• The Good and the BAT of Metabolic Sex Differences in Thermogenic Human Adipose Tissue.

Exercise & Physical Activity

• Systematic Review: Social Determinants of Health are Associated with Physical Therapy Use.
• RCT: Multi-Strategy Intervention Increases School Implementation and Maintenance of a Mandatory Physical Activity Policy.

Economics & Sociology

• RCT: Effect of a Smartphone App on Weight Change and Metabolic Outcomes in Asian Adults with Type 2 Diabetes.
• Behavioral Economic Approaches to Childhood Obesity Prevention Nutrition Policies: A Social Ecological Perspective.
• BMI Is Just a Number: Conflating Riskiness and Unhealthiness in Discourse on Body Size.
• Cost-Effectiveness of Bariatric Surgery and Non-Surgical Weight Management Programmes for Adults with Severe Obesity: A Decision Analysis Model.

Epidemiology

• COVID-19 and Obesity: An Epidemiologic Analysis of the Brazilian Data: "Our analysis supports obesity as a significant risk factor for the development of more severe forms of COVID-19".
• Sex-Specific Relationship between Abdominal Obesity and New-Onset Atrial Fibrillation in the General Japanese Population.
• Estimating the Effect of Nutritional Interventions Using Observational Data: The American Heart Association's 2020 Dietary Goals and Mortality.
• Dose-Dependent Associations of Dietary Glycemic Index, Glycemic Load, and Fiber with 3-Year Weight Loss Maintenance and Glycemic Status in a High-Risk Population.
• Associations of the Neighborhood Built Environment with Gestational Weight Gain.
• Reproducibility and Associations with Obesity and Insulin Resistance of Circadian-Rhythm Parameters in Free-Living Vs. Controlled Conditions.
• Obesity as a Risk Factor for Accelerated Brain Ageing in First-Episode Psychosis-A Longitudinal Study.
• Tobacco Use Prevalence and Transitions from 2013 to 2018 Among Adults with a History of Cardiovascular Disease.

Psychology & Neuroscience

• Food Addiction Comorbid to Mental Disorders in Adolescents: A Nationwide Survey and Register-Based Study.
• Association of Psychobehavioral Variables with HOMA-IR and BMI Differs for Men and Women with Prediabetes.
• Obesity, Putative Biological Mediators, and Cognitive Function in a National Sample of Children and Adolescents.

Equity and Disparities

• Association of BMI, Central Obesity, and Body Composition with Mortality Among Black Breast Cancer Survivors.
• Anthropometric Characteristics of Children Living in Food-Insecure Households in the USA.
• Research Brief: Identifying and Countering White Supremacy Culture in Food Systems.

Stigma

• Systematic Review: Evaluation of the Psychometric Properties of Self-Reported Weight Stigma Measures.
• Adverse Childhood Experiences Associated with Greater Internalization of Weight Stigma in Women with Excess Weight.
• Do Weight Perception and Bullying Victimization Account for Links between Weight Status and Mental Health Among Adolescents?

Policy Related

• South Africa's Health Promotion Levy: Excise Tax Findings and Equity Potential.
• Health Policy and Public Health Implications of Obesity in China.
• Evidence of a Health Risk ‘Signalling Effect’ Following the Introduction of a Sugar-Sweetened Beverage Tax.
• Polyphenols and Obesity Prevention: Critical Insights on Molecular Regulation, Bioavailability and Dose in Preclinical and Clinical Settings.

Intergenerational Effects

• Prenatal Exposure to Ambient Air Pollutants and Early Infant Growth and Adiposity in the Southern California Mother’s Milk Study.
• The Association of a Low Glycaemic Index Diet in Pregnancy with Child Body Composition at 5 years of Age.

Ecology, Evolution, & Energetics

• Diets Benefiting Health and Climate Relate to Longevity in Northern Sweden.
• Nutrition and Origin of US Chain Restaurant Seafood.

Methods

• RCT: Two Methods for Assessment of Choline Status in a Randomized Crossover Study with Varying Dietary Choline Intake in People: Isotope Dilution MS of Plasma and in Vivo Single-Voxel Magnetic Resonance Spectroscopy of Liver.
• Perspective: Application of N-Of-1 Methods in Personalized Nutrition Research.
• Reliability of GENEActiv Accelerometers to Estimate Sleep, Physical Activity, and Sedentary Time in Children.

Mathematical and Quantitative

• Review: Multicomponent Density Models for Body Composition: The Dual Energy X-Ray Absorptiometry Volume Approach.
• Preprint: Analyze the Impact of Healthy Behavior on Weight Change with a Mathematical Model Using the Harris-Benedict Equations.

Commentary

• Calories? The House Always Wins.
• Does Obesity Raise the Risk for Long COVID?
• The Origin and Evolution of the Paleo Diet.
• Perspective: The Saturated Fat–Unsaturated Oil Dilemma: Relations of Dietary Fatty Acids and Serum Cholesterol, Atherosclerosis, Inflammation, Cancer, and All-Cause Mortality.
• Wegovy Approved: Radical or Incremental Progress?
• Is There a Link between Sugar Intake and Cancer?

General

• Senolytics Reduce Coronavirus-Related Mortality in Old Mice.
• How to Make Sense of Contradictory Science Papers.
• Virtual Reality Platform Takes Travel Back in Time.
• The World Saw a Shark-Pocalypse 19 Million Years Ago, and We Don’t Know Why.
• COVID-19 & the Urgent Case for a Greater Focus on One Health.
• Rampant Tooth Loss Across 200 Million Years of Frog Evolution.
• Can Joy and Rigor Co-Exist in Science?
• Venom and Social Behavior: The Potential of Using Spiders to Evaluate the Evolution of Sociality Under High Risk.
• Scientific Publishing Needs to Embrace the Rapid Correction.

Announcements

• Applications Open: The Mathematical Sciences in Obesity Research Short Course: Friday, July 23rd to Friday, August 13th, 2021.
• Applications Open: Strengthening Causal Inference in Behavioral Obesity Research Short Course: Friday, September 10th to Friday, October 1st, 2021.
• Webinar Registration: Better Mental and Metabolic Health for Vulnerable Populations.
• Position: Nutrition Science Tenure/Tenure-Track: Full/Associate/Assistant Professor Search.
• Position: Nutrition Science Non-Tenure-Track: Clinical Full/Associate/Assistant Professor; Senior Lecturer/Lecturer Search.
• Dr. Javier Rojo Joins the IU School of Public Health-Bloomington Department of Epidemiology and Biostatistics as a Dean's Eminent Scholar.