Featured

• Impact of Prematurity on Nutrient Signaling and Protein Synthesis in Skeletal Muscle.
• Male Obesity Causes Adipose Mitochondrial Dysfunction in F1 Mouse Progeny Via Let-7-DICER Axis.
• Validation of Digital Anthropometric Measurements During Pregnancy: A Longitudinal Study.
• Podcast: The Science of Getting Science Right w/ Dr. David Allison.

Headline vs Study

• Headline: New Research Finds Link between Obesity and Breast Cancer Risks.
• Press Release: Obesity May Influence How Breast Cancer Spreads.
• Study: Transcriptomic Differences in Breast Cancer Samples from Women with and without BMI-Defined Obesity. Breast Cancer Risks nor Spreading Studied.

Contrary or Null Findings

• RCT: No Differential Effect (or Differential Lack of Effect) of Mediterranean and Healthy Eating Guideline Interventions on the Dietary Inflammatory Index in Rheumatoid Arthritis.
• RCT: "At habitual dietary protein intakes -0.9 g/kg body mass/d, further rBLG or WHEY supplementation did not influence muscle recovery or iMyoPS rates, suggesting that protein supplementation, at the intakes studied, may have limited efficacy as a tool to enhance muscle recovery and remodeling from damaging exercise."
• RCT: "Disclosure of obesity-related genetic information with tailored advice did not improve weight outcomes overall..."
• RCT: "Wild blueberry effects on postprandial glucose and appetite hormone responses were evident at anthocyanin doses of 300 mg and above but did not impact other outcomes in healthy adults."
• RCT: "A multicomponent mHealth sedentary reduction intervention led to changes at 5M in sit-to-stand transitions but was not effective in reducing sedentary time in adults who had undergone TKR..." (pdf)
• RCT: "A combination of heatwrap and exercise was not statistically superior to heatwrap alone or a sham heatwrap in the treatment of acute LBP, contrasting with the existing literature and guidelines."
• "Ultimately, biochar had limited and variable effects on reducing Pb ingestion risks in the studied vegetable agrisystems, which suggests that its remediation potential in urban agrisystems is context-dependent and may offer limited protection for growers and consumers in soils with elevated pH and organic matter."
• "Consumption of Energy drinks was found to be a risk factor, while caffeinated drinks had no effect" on overactive bladder.

Basic

• Gut Microbiota Alteration Contributes to Bone Marrow Mesenchymal Stem Cells Connexin43 Response to High-Fat Diet Induced Obesity in Mice.
• Effects of Exercise on PVAT-Derived Exosomes in the Modulation of Vascular Function in Obese Mice.
• Phosphomannomutase 1 Restrains Adipose Thermogenic Programming Via Inosine Signaling.
• Functional Rice Enriched with Resistant Starch Ameliorates Metabolic Dysregulation in High-Fat Diet-Induced Obese Mice.
• Biobank Analysis Reveals More Than 88,000 Genetic Associations with Metabolic Traits.
• Review: Hypothalamic Obesity.

Scientific Rigor & Scholarly Dialogue

• On Health and Understanding: Signature Threats to Signal in an Age of Noise.
• Editorial: Inconvenient for the Investigator but Convenient for Science: Trial Registration in the American Journal of Clinical Nutrition.
• Article: Reframing Basic Experimental Studies in Humans - Implications for Nutrition Science.

Clinical

• Validation of the Obesity Lifecycle Model Built to Assess the Cost Effectiveness of Novel Therapies in the Management of Obesity.
• Statins and Risk of Cardiovascular Disease: Emulating a Primary Prevention Trial in Breast Cancer Survivors.
• Cardio-Obstetrics Care: Challenging Scenarios in Heart Failure and Future Directions.

Children and Adolescents

• Diagnostic Performance of Obesity Indices for Predicting Hypertension Among Children Aged 6-13 Years in Polokwane.
• Letter: No Significant Change in Childhood Obesity.
• The Impact of Maternal Metabolic Flexibility During Gestation on Infant Adiposity in Individuals with Obesity.
• Prevalence, Trends, and Projections of Overweight and Obesity Among Children and Adolescents in Indonesia.
• Perinatal Outcomes in Pregnancies with Type 2 Diabetes and Weight Gain Less Than 5 Kilograms.

Surgery

• Cefazolin Surgical Prophylaxis in Obesity: A Body Composition-Driven Population Pharmacokinetic Approach.
• Metabolic and Bariatric Surgery in Mild Obesity.

Drugs

• Commentary: Incretin Therapies, Nutrition and Food Insecurity in the UK.
• The Evolving Landscape of Obesity Pharmacotherapy.

Food & Diet

• Associations Among Pork Intake, Weight-Loss, and Diet Quality Outcomes in a Commercial Weight-Management Program.
• RCT: Very Low-Carbohydrate Ketogenic Diet in Treatment-Naïve Women with Endometrial Cancer and Overweight.
• Tradeoffs between Convenience, Cost, and Healthy Eating Index for Menus Varying in Ultra-Processed Foods.
• The Whey of the Future: Is RBLG a New Player Within Protein Nutrition?
• Rethinking Dietary Fat for the Aging Brain: The Roles or Ketosis and Fat Quality in Cerebrovascular Aging and VCID.
• Meta-Analysis of RCTs: Long-Term Effects of Plant Vs. Animal Protein Supplementation on Body Composition, Muscle Strength, Physical Performance, and Cardiometabolic Risk Factors in Adults.
• Associations between Sugar-Sweetened Beverage Intake and Metabolic Syndrome Among Postmenopausal Black Women with Obesity and a Family History of Breast Cancer.

Caloric and Dietary Restriction

• RCT: Achieving Diabetes Remission Through Dietary Intervention.
• Self-Selected Dietary Intake and Association with Achieved Caloric Restriction.
• An In-Depth Analysis of the Molecular Changes Induced by Short-Term Calorie Restriction Before Living Kidney Donation.

Exercise & Physical Activity

• Physical Activity and Life Expectancy: A Life-Table Analysis.
• Meta-Analysis: Effects of Physical Activity-Based Digital Health Interventions on Psychological Outcomes in Adolescents with Overweight or Obesity.

Economics & Sociology

• Preprint: Weight Management Practices, Views, and Experiences Among Adults with Low Socioeconomic Position and Obesity.
• Dietary Inflammatory Index Mediates the Relationship of Social Determinants of Health with Blood Pressure and Obesity in the United States.
• Obesity and the Experienced Cultural, Economic, and Climate Variations Among Immigrants to High-Income Countries.
• Clinical and Economic Burden Among People with Knee Osteoarthritis and Obesity in the United States: A Retrospective Analysis.

Epidemiology

• National Prevalence of Clinical Obesity by BMI Class.
• Comparing Multiple Definitions of Obesity in a Large Nationwide Health Program.
• Association between Obesity and Abdominal Aortic Aneurysm: Complex Interactions between Waist Circumference and BMI.
• The Association between GLP-1R Expression and Cardiovascular-Kidney-Metabolic-Related Diseases in a Population without Diabetes or Obesity Population.
• Sarcopenic Obesity and Dementia Risk: Primary Associations and Landmark Analyses of Muscle Strength and Body Composition Trajectories.

Psychology & Neuroscience

• Impaired Boundaries, Sense of Self, and Personal Control: The Lifelong Trajectory of Co-Occurring Obesity and Adverse Childhood Experiences for Adult Women.
• Insomnia and Daytime Sleepiness Identify Distinct Behavioural Phenotypes of Binge Eating and Mood in Clinical Obesity: The MOCC Cohort (n = 2,016).
• Suicidality as a Potential Risk and Therapeutic Target During Widespread GLP-1 Receptor Agonists Use: Implications of Inflammation.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Socioeconomic Disparities and Nutritional Aging: How Food Insecurity and Financial Hardship Accelerate Health Decline in Older Adults.
• Preprint: Urban Environment and Socio-Economic Inequalities in Childhood Excess Weight: A Cross-Sectional Study in Geneva, Switzerland.
• Racial Disparities in Severe Maternal Morbidity During the COVID-19 Pandemic.

Stigma

• Social Perceptions of Weight Loss with Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists.
• RCT: Using Theatre to Tackle Weight Stigma in Primary Care: A Participatory Study on Empathy and Professional Awareness.

Policy Related

• Thesis: Do Cash Transfer Programs Work? Evidence from Peru’s Juntos Program on Child Outcomes Program on Child Outcomes.
• "The 2025-2030 Dietary Guidelines for Americans are associated with higher land, water and nitrogen use, and greenhouse gas emissions."
• Assessing Europe's Policy Readiness to Confront the MASLD/MASH Public Health Threat.
• Ending the Chronic Liver Disease Public Health Threat: Systemic Challenges Through the Patient Lens.
• Examining Public Support for Food Marketing Policy Among Adults in Canada.

Intergenerational Effects

• The Role of Fathers in the Intergenerational Transmission of Obesity.
• Scoping Review: Influence of Paternal Preconception Health on Miscarriage and Time to Pregnancy.

Ecology, Evolution, & Energetics

• Telomere Length in Metabolic Syndrome: Mechanisms, Epidemiology and Clinical Implications.

Methods

• Unsupervised Machine Learning for Scientific Discovery: Workflow and Best Practices.
• Precision Obesity Medicine: A Translational Perspective on Epigenetics, the Gut Microbiome, and AI-Assisted Multi-Omics Integration.
• Body Composition Phenotyping of Obesity in Children Aged 6-18 Years: Multi-Strategy Clustering and Interpretable Machine Learning.
• Mobile Applications for Body Composition Estimation: Functionality, Current Findings, and Future Directions.
• Skinfolds Measurement Protocols and Standards: A Narrative Review.

Commentary

• Podcast: Diet and Exercise Recommendations for Patients Taking GLP-1 Receptor Agonists.
• Podcast: Intense Exercise & Potential Heart Damage (aka Athlete's Heart).
• Podcast: Creatine for Muscle, Bone, Brain & Longevity (Plus Caffeine, Dosing, and Safety) with Dr. Darren Candow.
• Podcast: Dr. Mikhail Kosiborod Discusses the Evolving Science and Cardiometabolic Diseases Associated with Obesity.
• Podcast: The Silent Fuel Crisis Starving Your Brain | Dr Stephen Cunnane.
• New AI Model Finds a Cheaper Path to Healthier Eating.

General

• Podcast: Creatine Supplementation in the Management of Osteosarcopenia.
• Misinformation Blaming and Labelling May Damage Health, Science and Policy Making. (pdf)
• Impact of Socioeconomic Status on Patient Characteristics and Postoperative Outcomes in Colorectal Cancer Surgery.
• fMRI Research: Do We Need Statistically Better Studies, Larger Studies, or No More Studies?
• Universal Transcriptomic Hallmarks of Mammalian Ageing and Mortality.
• RCT: Cooling Vest May Reduce Body Fat in Obesity.
• RCT: Effectiveness of a Mobile Health Exercise Program for Adults with Mobility Disabilities.

Announcements

• The 2026 American Society of Animal Science (ASAS) Annual Meeting as Part of the Companion Animal Program, Including the Session on “Rigor and Reproducibility in Nutrition Research.”