Featured

• Body Shrinkage Due to Arctic Warming Reduces Red Knot Fitness and Feeding Ability in Tropical Wintering Range.
• (How) do Animals Know How Much They Weigh?
• The Acute Effects of Time-of-day-dependent High Fat Feeding on Whole Body Metabolic Flexibility in Mice.

Headline vs Study

• Headline: More BPA Exposure as a Fetus Leaves Kids Fatter at Age 7 - NYC Study.
• Study: Maternal Prenatal BPA Associated with Adiposity in Girls at Age 7, but Not in Boys or When Expressed in Tertiles, and Not Associated with BMIz at Age 5 or 7. (pdf)

Contrary or Null Findings

• "Overall, we found no evidence that reduced supermarket distance was associated with reduced levels of obesity for residents with type 2 diabetes."
• "We found no evidence that current or early life BMI influences AMH [antimüllerian hormone] concentrations in later life."
• "A low-carbohydrate high-fat diet increases weight gain and does not improve glucose tolerance, insulin secretion or β-cell mass in NZO mice."
• "We found no evidence that, for children aged 4-18 years in the UK, eating the evening meal after 20.00 hours was associated with excess weight or increased energy intake."
• No Association of the Single Nucleotide Polymorphism Rs8044769 in the Fat Mass and Obesity-associated Gene with Knee Osteoarthritis Risk and BMI.
• Probiotics Have No Effect on Gut Microbiota in Healthy People, Review Suggests.
• RCT: The Fat Content of Milk Does Not Affect the Plasma Glucose and Insulin Responses to a Meal.
• "Sitagliptin was not significantly better than placebo in reducing liver fat measured by MRI."

Basic

• Distinct Adipose Depots From Mice Differentially Respond to a High-Fat, High-Salt Diet.
• Cognitive Differences Between Sprague-Dawley Rats Selectively Bred for Sensitivity or Resistance to Diet Induced Obesity.
• Obesity Promotes PhIP-induced Small Intestinal Carcinogenesis in HCYP1A-db/db Mice: Involvement of Mutations and DNA Hypermethylation of Apc.
• Obesity Takes Its Toll on Visceral Pain: High-Fat Diet Induces Toll-Like Receptor 4-Dependent Visceral Hypersensitivity.
• Fibroblast Growth Factor 21 Expression in Mice with Altered Growth Hormone Action: Links to Obesity, Type 2 Diabetes Mellitus, and Increased Longevity.
• N-acetylcysteine Protects Mice From High Fat Diet-induced Metabolic Disorders.
• Adult NG2-Glia are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control.
• Neuronal Deletion of Ghrelin Receptor Almost Completely Prevents Diet-induced Obesity.
• Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High Fat Diet-Induced Insulin Resistance.
• Metabolic Alterations From Early Life Thyroxine Replacement Therapy in Male Ames Dwarf Mice are Transient.
• Chronic L-menthol-induced Browning of White Adipose Tissue Hypothesis: A Putative Therapeutic Regime for Combating Obesity and Improving Metabolic Health.

Scientific Rigor & Scholarly Dialogue

• Researchers Decry Study Warning of Low-carb Diet Risks.
• Serious About Scientific Integrity?
• No Metabolic Advantage to Ketogenic Diet - Video Interview.
• Defense of the Insulin-Carbohydrate Model Redux: A Response to Video.
• Perspective: RCTs are Not a Panacea for Diet-Related Research.
• Limitations of Using the Chronic Kidney Disease–Epidemiology Collaboration Equation for Measuring Renal Function in Obese Populations.

Clinical

• Effects of Transcranial Direct Current Stimulation (tDCS) on Binge-eating Disorder.
• The Effects of Weight Loss Approaches on Bone Mineral Density in Adults: A Systematic Review and Meta-analysis of RCTs.
• Hotspot Autoimmune T Cell Receptor Binding Underlies Pathogen and Insulin Peptide Cross-reactivity.

Children and Adolescents

• The Edmonton Obesity Staging System for Pediatrics.
• Associations Between Diet Behaviors and Measures of Glycemia, in Clinical Setting, in Obese Adolescents.
• Revised WIC Food Package and Children’s Diet Quality.

Surgery

• Microbiota-Derived Metabolites Associated with Metabolic Improvements After Gastric Bypass Surgery and Their Effects on Intestinal Cells in Vitro.
• The Effect [association] of Pregnancy Before And/or After Bariatric Surgery on Weight Loss.

Drugs

• BAP Guidelines on the Management of Weight Gain, Metabolic Disturbances and Cardiovascular Risk Associated with Psychosis and Antipsychotic Drug Treatment.
• Effect of Combination Therapy of Melatonin and Orlistat on High Fat Diet Induced Changes in Lipid Profiles and Liver Function Parameters in Serum of Rats.
• Glucose Variability in a 26-Week Randomized Comparison of Mealtime Treatment with Rapid-Acting Insulin Versus GLP-1 Agonist in Participants with Type 2 Diabetes at High Cardiovascular Risk.
• A 52-week Pilot Study of the Effects of Exenatide on Body Weight in Patients with Hypothalamic Obesity.
• Association Between Insulin Monotherapy Versus Insulin Plus Metformin and the Risk of All-Cause Mortality and Other Serious Outcomes: A Retrospective Cohort Study.

Food & Diet

• Early and Sustained Exposure to High-sucrose Diet Triggers Hippocampal ER Stress in Young Rats.
• Dietary Composition Affects the Development of Cognitive Deficits in WT and Tg AD Model Mice.
• Review: Gut Microbiota and Metabolic Health: The Potential Beneficial Effects of a Medium Chain Triglyceride Diet in Obese Individuals.
• The 2015 Dietary Guidelines Advisory Committee Scientific Report: Development and Major Conclusions.
• Review: Foods, Nutrients, and Dietary Patterns: Interconnections and Implications for Dietary Guidelines.
• Zinc Isotope Ratios of Bones and Teeth as New Dietary Indicators: Results From a Modern Food Web (Koobi Fora, Kenya).

Caloric Restriction

• Chronic Calorie Restriction Downregulates Skeletal Muscle MTORC1 Signaling Independent of Dietary Protein Level and Associated MicroRNA Expression in Male Rats.
• Methionine Restriction on Lipid Metabolism and Its Possible Mechanisms.

Exercise & Physical Activity

• QuickStats: Percentage of U.S. Adults Who Met the 2008 Federal Physical Activity Guidelines for Aerobic and Strengthening Activity,* By Sex — National Health Interview Survey,† 2000–2014.
• “Weighing” the Effects of Exercise and Intrinsic Aerobic Capacity: Are There Beneficial Effects Independent of Changes in Weight?
• Association of Leisure-Time Physical Activity with Risk of 26 Types of Cancer in 1.44 Million Adults.
• Twenty Year Fitness Trends in Young Adults and Incidence of Prediabetes and Diabetes: The CARDIA Study.
• Glycemic Reductions Following Water- and Land-based Exercise in Patients with Type 2 Diabetes Mellitus.

Economics & Sociology

• Can Socioeconomic Factors Explain Geographic Variation in Overweight in Norway?
• Harsh Parenting and Food Insecurity in Adolescence: The Association with Emerging Adult Obesity.
• Socioeconomic Status and Glycemic Control in Adult Patients with Type 2 Diabetes: A Mediation Analysis.
• The Role of Life-course Socioeconomic and Lifestyle Factors in the Intergenerational Transmission of the Metabolic Syndrome: Results From the LifeLines Cohort Study.

Epidemiology

• Could a Few Extra Pounds Help You Live Longer?
• Maternal Obesity and the Risk of Neural Tube Defects in Offspring: A Meta-analysis.
• Childhood Body Weight in Relation to Cause-Specific Mortality - 67 Year Follow-up of Participants in the 1947 Scottish Mental Survey.
• Energetics of Aging and Frailty.
• "This study shows that life-long maintenance of lean body mass and attenuated accumulation of body fat were key factors in achieving a longer lifespan" in Labrador retrievers.
• Maternal GWG Above 0.9 kg/week May Increase the Risk of Cerebrovascular Disease in the Adult Offspring, but Not All-cause Mortality or Cardiovascular Disease.
• Characteristics of Patients Potentially Eligible for Pharmacotherapy for Weight Loss in Primary Care Practice in the United States.

Psychology

• Nonverbal and Paraverbal Behavior in (simulated) Medical Visits Related to Genomics and Weight: A Role for Emotion and Race.
• Weight Self-stigma and Its Association with Quality of Life and Psychological Distress Among Overweight and Obese Women.
• ‘Strong is the New Skinny’: A Content Analysis of #fitspiration Images on Instagram.
• Is Friendship Network Weight Status Associated with One's Own Psychological Well-Being? It Depends on One's Own Weight Status.
• The Influence of Maternal Psychosocial Characteristics on Infant Feeding Styles.
• Binge Eating, Disinhibition and Obesity.

Equity and Disparities

• Too Fat for Me: Obesity Discrimination in Employment.
• Exploring the Impact of Early Life Factors on Inequalities in Risk of Overweight in UK Children: Findings From the UK Millennium Cohort Study.
• Multi-ethnic Genome-wide Association Study Identifies Novel Locus for Type 2 Diabetes Susceptibility.
• Differences in the Protective Effect of Exclusive Breastfeeding on Child Overweight and Obesity By Mother’s Race.

Stigma

• Perceived Responsibility and Sympathy for Misfortunes of the Obese.
• The Relationship Between Weight-Based Prejudice and Attitudes Towards Obesity-Reducing Public Policies.
• Means, Ends and the Ethics of Fear-based Public Health Campaigns.

Policy Related

• Influence of Teachers' Personal Health Behaviors on Operationalizing Obesity Prevention Policy in Head Start Preschools.
• Indicators of a Health Promoting Local Food Environment: A Conceptual Framework to Inform Urban Planning Policy and Practice.

Intergenerational Effects

• Effect of Maternal and Paternal Nutrition on DNAmethylation in the Offspring: A Systematic Review of Human and Animal Studies.
• Obesity-related DNA Methylation at Imprinted Genes in Human Sperm: Results From the TIEGER Study.
• Examining Maternal Obesity Effects on Oogenesis, Follicular Development, and Embryonic Myogenesis.
• Tumor Necrosis Factor Alpha Levels in Blood Cord is Directly Correlated with the Body Weight of Mothers.

Ecology, Evolution, & Energetics

• Basking Hamsters Reduce Resting Metabolism, Body Temperature and Energy Costs During Rewarming From Torpor.
• Metabolic Flexibility: Hibernation, Torpor, and Estivation.
• Reproductive Success is Predicted By Social Dynamics and Kinship in Managed Animal Populations.
• Low Energy Intake Plus Low Energy Expenditure (low Energy Flux), Not Energy Surfeit, Predicts Future Body Fat Gain.

Methods

• Reliability and Validity of the Physical Education Activities Scale.
• Estimating Fat-free Mass in Elite-level Male Rowers: A Four-compartment Model Validation of Laboratory and Field Methods.

Mathematical and Quantitative

• A China-USA Comparative Study of Peer Influence on Childhood Obesity and Eating Behavior: Social Network Analysis and Agent Based Modeling.
• Simulation of Cryolipolysis as a Novel Method for Noninvasive Fat Layer Reduction (PDF).
• Food Category Consumption and Obesity Prevalence Across Countries: An Application of Machine Learning Method to Big Data Analysis.

Commentary

• Lessons of the Biggest Loser: From Science to Nonsense.
• Why do We Get Fat?
• Another Ding for the BMI.
• What is 'Natural' Food? A Riddle Wrapped in Notions of Good and Evil.
• Our Bodies Make Vitamin D Naturally. So Why do Americans Spend Billions on Supplements?

General

• Scientists Have Identified a Living Eukaryote that Lacks Mitochondria, Thought Essential for that Type of Cell to Function.
• Cytochrome B5 Reductase and the Control of Lipid Metabolism and Healthspan.
• Hepatic NAD+ Deficiency as a Therapeutic Target for NAFLD in Aging.
• The Zombie Literature: Retractions are on the Rise. But Reams of Flawed Research Papers Persist in the Scientific Literature. Is It Time to Change the Way Papers are Published?
• Book Review: The Stanchions of Statistics.
• Well-known Scientists Ready to Stem the Onslaught of Pseudoscience in the EU.
• Five “Don'ts” for Introducing a Female Speaker (And Why This Matters).
• Brain Waves Predict Speed of Second Language Learning.

Video & Audio

• Gary Taubes Lecture at UMass Medical School April 20 2016.
• Hovering on a High Fructose Diet: Hummingbirds Can Fuel Expensive Flight with Glucose or Fructose.

Announcements

• Michael Jensen Named Winner of the World Obesity Federation’s 2016 Clinical Research Award.
• Barry Popkin Named Winner of the World Obesity Federation’s 2016 Population Science and Public Health Award.
• CALL FOR ABSTRACTS: 2017 National Food Safety Education Conference.
• Hands-On Obesity Training in the Bariatric Simulation Suite, Edmonton, May 24, 2016.
• Research Reproducibility 2016: Conference.
• Announcement of PhD Student Research Assistantships and Post-Doctoral Fellowship Positions.
• National Microbiome Initiative Launched.
• The Mathematical Sciences in Obesity, Mon 6/13/2016 - Fri 6/17/2016.
• Opportunities: Post-Doctoral Fellowship in Obesity Research.
• Strengthening Causal Inference in Behavioral Obesity Research, Mon 7/25/2016 - Fri 7/29/2016.