05/15/26
Featured
- Examining Widely Held Propositions on Human Dietary Protein Needs and Benefits: A Critical Review of the Science That Shapes Both the Data and Our Understanding of an Essential Macronutrient.
- A Fuel Partitioning Perspective on Appetite Suppression by GLP-1 Receptor Agonists.
- INS-17 Acts as a Nutrient Deprivation Signal to Mediate Adult IIS-Regulated Associative Behaviors in C. elegans.
- The Conundrum of Exercise for Weight Management in the GLP-1 Receptor Agonist Era.
Headline vs Study
- Headline: Breakthrough Bone Discovery Could Lead to “Exercise-In-A-Pill” for Osteoporosis.
- Press Release: HKUMed Uncovers the Mechanism Behind Exercise-Induced Bone Strengthening, Paving the Way for Novel Osteoporosis Treatment.
- Study: Piezo1 Activation Suppresses Bone Marrow Adipogenesis to Prevent Osteoporosis by Inhibiting a Mechanoinflammatory Autocrine Loop... In Mice and Cells.
Contrary or Null Findings
- RCT: A 4-Week Caloric Restriction with High Volume Resistance-Training and High-Protein Diet Does Not Increase Fat-Free Mass Sparing but Increases Strength.
- RCT: Increasing Protein Dose Does Not Further Augment Muscle Protein Synthesis in Critical Illness.
- "Contrary to our hypothesis, there were no sex differences in frequency of ARFID [Avoidant/Restrictive Food Intake Disorder] clinical phenotypes, appetite-regulating hormone levels, or brain activation."
- [In mice] "contrary to what is commonly thought, nitrate supplementation can have detrimental, if temporary, effects on cardiac contractility, especially in females."
- "In conclusion, ...the hypothesis that SID of indispensable AA and daily nitrogen retention is not affected by dietary protein concentration was rejected."
- RCT: Moderate Coffee Intake Does Not Significantly Affect Short-Term Bioelectrical Impedance Measurements in Healthy Women.
- RCT: "A single dose of sucrose solution does not improve oral rehydration intake in children with gastroenteritis in the ED."
Basic
- Meta-analysis: Hepatic Lipids as Molecular Targets in Obesity-Associated Insulin Resistance in Rodent Models.
- Cell-Type-Targeted Mitochondrial Transplantation Rescues Cell Degeneration.
- High-Fat Diet Feeding Induces Organ-Specific Vascular Remodeling with Distinct Temporal Dynamics in Male Mice.
- ITIH5 Drives Adipocyte Differentiation and Obesity-Associated Metabolic Dysregulation Via PI3K/AKT Signaling Activation.
- Leptin Mediates the Effects of Sulfur Amino Acid Restriction on Food Intake and Body Weight in Mice.
Scientific Rigor & Scholarly Dialogue
- Podcast: SIGMA NUTRITION - How to Interpret Nutrition Research – David Allison, PhD.
- Podcast: What Nutrition Epidemiology Can (and Can’t) Tell Us with Dr. Russell De Souza.
- Podcast: Pointing Out Lapses in Rigor in Research on Fasting, Nutrient Timing & CGMs: Interpreting the Evidence with Prof. James Betts.
- What Diet Trials Can and Can't Tell Us - Mitigating Misinformation in Nutrition Science.
- Article: Semaglutide and Cardiovascular Outcomes by Baseline and Changes in Adiposity Measurements: A Prespecified Analysis of the SELECT Trial.
- Letter: #1: Semaglutide, Weight Loss, and Cardiovascular Outcomes in the SELECT Trial.
- Letter: #2: Semaglutide, Weight Loss, and Cardiovascular Outcomes in the SELECT Trial.
- Response: Semaglutide, Weight Loss, and Cardiovascular Outcomes in the SELECT Trial – Authors' Reply.
- Retraction: The Value of Subcutaneous Tissue Closure and Drain in Obese Women Undergo Elective Caesarean Section: A Randomized Controlled Trial.
Clinical
- Encouraging Short-Term Goals for Older Adults with Diabetes.
- Dietary Fiber and GLP-1 Receptor Agonists in Obesity Management: Converging Mechanisms, Interactions, and Strategies for Durable Weight Control.
- Gut Microbiota Responses to Isocaloric Macronutrient Modulation in Tissue-Specific Insulin Resistance: A Secondary Analysis of the PERSonalized Glucose Optimization Through Nutritional Intervention (PERSON) Randomized Trial.
- Novel Energy Balance Tracking to Support Personalised AI Health Coaching: A Real-World Evaluation of the ENHANCE Framework.
Children and Adolescents
- CDC - Childhood Obesity Facts.
- Food Preparation Skills and Obesity Risk in European Children Aged 6-9 Years.
- Association of Sleep Duration at 1.5 Years with Overweight/Obesity at 3 Years and Effect Modification by Allergic Conditions.
Surgery
- Review: Obesity Management: Surgical Interventions.
- Cohort Study: Prognostic Significance of Sarcopenic Obesity in Colorectal Cancer Surgery.
- Case Control Analysis: Risk Factors Associated with Colon Cancer in Adults with Obesity and Association with Prior Bariatric Surgery.
- Systematic Review: The Role of Total Small Bowel Length and Its Measurement in Metabolic Bariatric Surgery.
Drugs
- A Brain Reward Circuit Inhibited by Next-Generation Weight-Loss Drugs in Mice.
- Constipation Linked to Greater Weight Loss on Semaglutide.
Food & Diet
- Biological Evaluation of Hoodia gordonii Cactus Against Obesity on Experimental Animals.
- Review: Obesity, Inflammation, and the Mediterranean Diet in Cancer.
Caloric and Dietary Restriction
- Caloric Restriction Decelerates Premature Aging and Cognitive Decline in Mice with Deficient DNA Repair.
- Diet-Based Weight-Loss Intervention Is Not Associated with a Meaningful Change in Lean Soft Tissue.
Exercise & Physical Activity
- Thesis: Health, the Body, and Movement: What Is Health and Physical Education For?
- Maternal and Paternal Pathways Linking Health Literacy, Physical Activity, and BMI to Adolescent Physical Activity and Mental Health: A Structural Equation Modeling Study.
Economics & Sociology
- Wrist-Worn Accelerometer Measured Sleep Fragmentation and Obesity Risk: Socioeconomic Gradients and Mediation by Allostatic Load.
- The Cost of Capital of Walmart, Kroger, Albertsons, Costco, and Publix in 2025.
Epidemiology
- Systematic Review: Association between Obesity and the Risk of Skin and Soft Tissue Infections in European Populations.
- Association of General Obesity, Metabolically Healthy Obesity, and Abdominal Adiposity Markers with Elevated Liver Enzymes.
- Association between Different Metabolic Obesity Phenotypes and Hyperuricemia: The Modifying Role of Liver Enzymes.
- The Association between Weight-Adjusted Waist Circumference Index and Risks of Cardiovascular and All-Cause Mortality.
Psychology & Neuroscience
- Egg Intake and the Incidence of Alzheimer's Disease in the Adventist Health Study-2 Cohort Linked with Medicare Data.
- Systematic Review: Determining the Effects of Lifestyle Factors Including Smoking, Alcohol Consumption, Physical Activity, and Diet on the Risk and Progression of Dementia.
Differential Population Circumstances, Exposures, Outcomes, and Effects
- Improving the Food Environment at Harvard University: A Unified Procurement Policy Intervention.
- Disparities in Atrial Fibrillation Metabolic Risk in Indonesia: Time for Sociodemographic Targeted Interventions.
Ethics
- “I Don't Know If Medical Interventions Help Obesity”: Perspectives from Patients with Obesity and the General Public on Obesity Awareness.
- Teaching Approaches to Ethical Generative Artificial Intelligence Use in Agricultural Economics Classrooms.
Stigma
- Family Sources of Weight Teasing and Associations with Adolescents' Unhealthy Eating Behaviors, Weight Bias Internalization, and Body Appreciation.
- Residual Stigma and Internalized Weight Bias Following Metabolic Bariatric Surgery.
- Politeness Strategies in Doctor-Patient Communication on Weight Loss.
Policy Related
- Abstract: State Support for Plant-Based Meals in U.S. School Lunch Programs: A National Policy Analysis.
- Correspondence: School Based Physical Fitness Testing: Challenges and Opportunities.
- Impact Assessment of Telehealth Medical Nutrition Therapy for Managing Cardiovascular Disease Risk in Rural and Remote NSW: The Healthy Rural Hearts Study.
- Food Security Outcomes and Postintervention Experiences in a Produce Prescription Pilot: A Mixed-Methods Study.
Intergenerational Effects
- Association between Maternal Obesity and Neonatal Folate and Vitamin B12 Status: Functional Biomarkers and Placental Transporters.
- Effect of Maternal Obesity on the Concentration of Calcium, Magnesium, and Zinc in Human Milk between the First and Second Month of Lactation.
Ecology, Evolution, & Energetics
- Heat Stress Disrupts Maternal Care Through Independent Effects on Mothers and Eggs.
- Implications of New Immigration Policies for Specific US Agricultural Sectors.
Methods
- Commercially Available Mobile Health Applications for Obesity Across the Lifespan.
- Mobile Health Applications for Type 2 Diabetes Remission and Weight Management: A Position Statement on Efficacy, Regulation, and Ethical Implementation.
Mathematical and Quantitative
Commentary
- Podcast: The Food Combo That Makes Us Overeat - and It's in Breast Milk | John Speakman, PhD.
- Ultra‑processed Food: Why the Debate Needs Less Fear and More Clarity.
- Science Notes: Food as Medicine.
- GLP-1 Drugs are Changing How People Shop for Food and Clothes.
- What the NY Times Got Right - and What It Missed - About GLP-1 Drugs. By: Dr. Barry Sears.
- The Seductive Story of Obesity as a “Diet-Related” Disease.
- Podcast: MILK - Dangerous or a Superfood.
- How the Ketogenic Diet Shapes the Microbiome to Influence Cancer Immunotherapy Outcomes: An Exploration of Clinical Trials and Their Results.
- The ‘Velocity of Obesity’ Aims to Show Which Nations are Slowing an Epidemic.
General
- Podcast: Is Everything Inflammation?
- Testosterone Therapy Is Trending. Who Really Needs It, and Why?
- What Can We Gain by Losing Infinity?
- Podcast: Using a Biocultural Approach to Understand Food Allergies, Consumption Patterns, and Guidelines with Erin Maxwell (Hosein).
- Is Meat the Real Villain?
- Podcast: Dr. Elizabeth Yurth: The Science of Ketones, Hormones, and Faster Recovery.
- Use of Semaglutide and Tirzepatide in Rheumatic and Musculoskeletal Diseases: Insights on Initiation Patterns and Weight Loss from the Rheumatology Informatics System for Effectiveness Registry.
- Construct Validity and Confirmatory Factor Analysis of the National Center on Health, Physical Activity and Disability Wellness Assessment Tool.
Announcements
- Final Rule Restores Whole and 2% Milk Options in School and Child Nutrition Programs.
- Rice, Baylor College of Medicine Renew Superfund Research Program to Tackle Toxic Pollutants and Protect Public Health.
- American Society for Nutrition Foundation and Novo Nordisk Foundation Announce 2026 Awardees Advancing Nutrition and Obesity Science: Dr. Anna Thalacker-Mercer and Dr. Rachel Whooten.