05/05/23
Featured
- Pharmacotherapy for Obesity: Recent Evolution and Implications for Cardiovascular Risk Reduction.
- Biological Normalcy and Body Fat: Obesity Prevalence, Fat Stigma, and Allostatic Load Among Late Adolescents and Young Adults.
- Total Daily Energy Expenditure Has Declined over the Past Three Decades Due to Declining Basal Expenditure, Not Reduced Activity Expenditure.
- Wearable and Digital Devices to Monitor and Treat Metabolic Diseases.
Headline vs Study
- Headline: Keto Diet Doubles the Risk of Heart Attack, Stroke: Study.
- Press Release for Meeting Presentation: Single Lower-Carbohydrate, Higher-Fat, Self-Reported Diet Assessment Associated with Cardiovascular Events. Ketogenesis Not Measured. Causal Increase in Risk Not Established.
Contrary or Null Findings
- RCT: An Acute Bout of Endurance Exercise Does Not Prevent the Inhibitory Effect of Caffeine on Glucose Tolerance the Following Morning.
- Review: Current Evidence Shows No Influence of Women's Menstrual Cycle Phase on Acute Strength Performance or Adaptations to Resistance Exercise Training.
- A Chronic High-Fat Diet Does Not Exacerbate Muscle Atrophy in Fast-Twitch Skeletal Muscle of Aged Mice.
- Cisplatin Decreases Voluntary Wheel-Running Activity but Does Not Impair Food-Motivated Behavior in Mice.
- Naupliar Exposure to Acute Warming Does Not Affect Ontogenetic Patterns in Respiration, Body Size, or Development Time in the Cosmopolitan Copepod Acartia Tonsa.
- RCT: Daily Intranasal Insulin at 40IU Does Not Affect Food Intake and Body Composition: A Placebo-Controlled Trial in Older Adults over a 24-Week Period with 24-Weeks of Follow-Up.
- How Negative Affect Does and Does Not Lead to Binge Eating-The Importance of Craving and Negative Urgency in Bulimia Nervosa.
- RCT: High-Dose Spermidine Supplementation Does Not Increase Spermidine Levels in Blood Plasma and Saliva of Healthy Adults.
Basic
- Systematic Metabolomic Studies Identified Adult Adiposity Biomarkers with Acetylglycine Associated with Fat Loss in Vivo.
- Semaphorin 4B Is an ADAM17-Cleaved Adipokine That Inhibits Adipocyte Differentiation and Thermogenesis.
- Islr Regulates Insulin Sensitivity by Interacting with Psma4 to Control Insulin Receptor Alpha Levels in Obese Mice.
Scientific Rigor & Scholarly Dialogue
- Chowing Down: Diet Considerations in Rodent Models of Metabolic Disease.
- Article: Risk-Benefit Balance Associated with Obstetric, Neonatal, and Child Outcomes After Metabolic and Bariatric Surgery.
- Letter: Is Maternal Metabolic Bariatric Surgery the Best Solution to Tackle the Childhood Obesity Pandemic?
- Response: Is Maternal Metabolic Bariatric Surgery the Best Solution to Tackle the Childhood Obesity Pandemic?—Reply.
Clinical
- Association between Primary Graft Function and 5-Year Outcomes of Islet Allogeneic Transplantation in Type 1 Diabetes: A Retrospective, Multicentre, Observational Cohort Study in 1210 Patients from the Collaborative Islet Transplant Registry.
- Differences between HbA1c and Glucose-Related Variables in Predicting Weight Loss and Glycaemic Changes in Individuals with Overweight and Hyperglycaemia - the PREVIEW Trial.
- Digital Health Solutions for Weight Loss and Obesity: A Narrative Review.
- Gestational Diabetes Is Characterized by Decreased Medium-Chain Acylcarnitines and Elevated Purine Degradation Metabolites Across Pregnancy: A Case–Control Time-Course Analysis.
- RCT: Effects of Smartphone-Based Remote Interventions on Dietary Intake, Physical Activity, Weight Control, and Related Health Benefits Among the Older Population with Overweight and Obesity in China.
- Historical Review of the Use of Relative Risk Statistics in the Portrayal of the Purported Hazards of High LDL Cholesterol and the Benefits of Lipid-Lowering Therapy.
Children and Adolescents
- Meta-Analysis: Mediterranean Diet-Based Interventions to Improve Anthropometric and Obesity Indicators in Children and Adolescents.
- Childhood Obesity at the Crossroads of Science and Social Justice.
- Long-Term Outcomes of Sleeve Gastrectomy from Adolescence to Adulthood.
- Meta-Analysis: Independent and Joined Association between Socioeconomic Indicators and Pediatric Obesity in Spain.
- Longitudinal Trajectories of Dietary Fibre Intake and Its Determinants in Early Childhood.
- Systematic Review: Attachment, Feeding Practices, Family Routines and Childhood Obesity.
Surgery
- Assessing the Accuracy of Responses by the Language Model ChatGPT to Questions Regarding Bariatric Surgery.
- Meta-Analysis: Long-Term Results of Bariatric Surgery in Adolescents with at Least 5 Years of Follow-Up.
- Prior Metabolic Surgery Is Associated with Reduced COVID-19 Severity: Systematic Analysis from Year One of the COVID-19 Pandemic.
Drugs
- Medications for the Treatment of Obesity.
- RCT: Evaluating the Safety and Efficacy of the Leukotriene Receptor Antagonist Montelukast as Adjuvant Therapy in Patients with Obesity and Type 2 Diabetes Mellitus.
Food & Diet
- Meta-Analysis: Important Food Sources of Fructose-Containing Sugars and Adiposity.
- Popular Diets as Selected by Adults in the United States Show Wide Variation in Carbon Footprints and Diet Quality.
- Popular Dietary Patterns: Alignment with American Heart Association 2021 Dietary Guidance: A Scientific Statement from the American Heart Association.
Caloric and Dietary Restriction
- Caloric State Modulates Locomotion, Heart Rate and Motor Neuron Responses to Acute Administration of D-Amphetamine in Zebrafish Larvae.
- Intestinal Epithelial Autophagy Is Required for the Regenerative Benefit of Calorie Restriction.
Exercise & Physical Activity
- Interaction of Exercise and Meal Timing on Blood Glucose Concentrations.
- The 3Es: Keys to Empowering Women in the Weight Room.
- Systematic Review: Correlates of Physical Activity Habits in Adolescents.
Economics & Sociology
- Socioeconomic Position and the Influence of Food Portion Size on Daily Energy Intake in Adult Females.
- Extreme Violence and Weight-Related Outcomes in Mexican Adults.
Epidemiology
- Mastication Inefficiency Due to Diminished or Lack of Occlusal Support Is Associated with Increased Blood Glucose Levels in Patients with Type 2 Diabetes.
- Back Onside Protocol: A Physical Activity Intervention to Improve Health Outcomes in People Who are Unemployed or at Risk of Unemployment.
- Dietary Phytochemical Index Is Favorably Associated with Oxidative Stress Status and Cardiovascular Risk Factors in Adults with Obesity.
- Lifestyle Mediators of Associations Among Siestas, Obesity, and Metabolic Health.
- Eating Speed and Height Loss in Relation to Overweight: A Retrospective Study.
Psychology & Neuroscience
- Astrocyte-Mediated Transduction of Muscle Fiber Contractions Synchronizes Hippocampal Neuronal Network Development.
- Acute Effect of Moderate and High-Intensity Interval Exercises on Asprosin and BDNF Levels in Inactive Individuals of Normal Weight and with Obesity.
Equity and Disparities
- Dimensions of Sleep Quality are Related to Objectively Measured Eating Behaviors Among Children at High Familial Risk for Obesity.
- Association of Snacking Frequency, Size, and Energy Density with Weight Status Among Preschool-Aged Children in the United States.
Stigma
- Systematic Review: Assessment and Impact of Paediatric Internalized Weight Bias.
- Support for Weight-Related Anti-Discrimination Laws and Policies: Modelling the Role of Attitudes Toward Poverty Alongside Weight Stigma, Causal Attributions About Weight, and Prejudice.
Policy Related
- The Development of the Dutch “National Model Integrated Care for Childhood Overweight and Obesity”.
- Municipal Officials’ Perspectives on Policymaking for Addressing Obesity and Health Equity.
- Systematic Review: Influences of the Community and Consumer Nutrition Environment on the Food Purchases and Dietary Behaviors of Adolescents.
Intergenerational Effects
- Maternal Western Diet Mediates Susceptibility of Offspring to Crohn's-Like Colitis by Deoxycholate Generation.
- Influence of Parental and Offspring Dietary Behaviors on the Association of Overweight and Obesity between Two Generations: Results from a Cross-Sectional Analysis of Parent-Offspring Trios in China.
Ecology, Evolution, & Energetics
- Baseline Corticosterone Levels in Spadefoot Toads Reflect Alternate Larval Diets One Year Later.
- A Genomic Timescale for Placental Mammal Evolution.
- Saving Energy Via Short and Shallow Torpor Bouts.
- Long-Term Survival, Temperature, and Torpor Patterns.
Methods
- Design and Implementation of a Time-Restricted Eating Intervention in RCT Eating Study.
- Mathematical Approaches in the Study of Diabetes Mellitus.
- Association between Intra-Muscular Adipose Tissue Imaging Volume and Serum Adipokines Level with Obesity.
- Building Machine Learning Models to Correct Self-Reported Anthropometric Measures.
Commentary
- Challenges in Measuring Energy Balance and Body Composition.
- Will Weight-Loss Drugs Put Diet Charlatans Out of Business? I Hope So.
- "‘Real-world evidence does not mean non-randomized, sloppy observational studies for which you can’t really draw an adequate conclusion,’ said [FDA Commissioner Robert] Califf."
- The Oddness of Weight Bias in Eating Disorders.
- Obesity as a Main Threat to Future Improvements in Population Health: Policy Opportunities and Challenges.
- Personal Convictions, Money, and Conflicts.
- Sunshine, Lollipops, Rainbows, and GLP-1 Meds.
- Is Mounjaro Gliding Toward an Obesity Approval?
- ”The Fat Child and the Concept of 'Pound-Years'.” (pdf)
General
- Cooking Methods and Kitchen Ventilation Availability, Usage, Perceived Performance and Potential in Canadian Homes.
- Human Pluripotent Stem Cells from Patients with and without Diabetes Improve Retinal Pathology in Diabetic Mice.
- Human Capital Development Factors and Black Adolescent Tobacco and Cannabis Use.
- Contextual Modifiers of Healthspan, Lifespan, and Epigenome in Mice Under Chronic Social Stress.
- Fecal Transplant from Myostatin Deletion Pigs Positively Impacts the Gut-Muscle Axis.
- Earliest Animal Likely Used Chemical Signaling to Evolve Into Multicellular Organism.
- Genetic Map of Tasmanian Devil Cancers Hints at Their Future Evolution.
- 'Biological Aging' Speeds Up in Times of Great Stress, but It Can Be Reversed During Recovery.
Announcements
- Registration Open: Strengthening Causal Inference in Behavioral Obesity Research, June 26th to June 30th in Person at the IU School of Public Health-Bloomington.
- Registration Open: The Mathematical Sciences in Obesity Research, July 31st to August 4th in Person at the IU School of Public Health-Bloomington.
- Obesity Symposium 2023. May 19th. Indiana University.
- Course: The Boston Course in Obesity Medicine June 13-16.