04/26/19
Featured
- Combining Biomarker and Self-reported Dietary Intake Data: A Review of the State of the Art and an Exposition of Concepts.
- RCT: Portion Size Has Sustained Effects Over 5 Days in Preschool Children.
- Physical Activity and Fitness Among Pediatric Cancer Survivors: A Meta-analysis of Observational Studies.
Headline vs Study
- Headline: Exercise Makes You Happier than Money, According to Yale and Oxford Research.
- Study: Association between physical exercise and mental health in 1·2 million individuals: "physical exercise was significantly and meaningfully associated with self-reported mental health burden in the past month. More exercise was not always better."
Contrary or Null Findings
- RCT: Six Weeks of Morning Fasting Causes Little Adaptation of Metabolic or Appetite Responses to Feeding in Adults with Obesity.
- RCT: "leucine-enriched whey protein isolate supplementation did not confer any additional benefit in those already consuming ample amounts of dietary protein at trial enrolment" in sarcopenia.
- RCT: Videogames that Encourage Healthy Behavior Did Not Alter Fasting Insulin or Other Diabetes Risks in Children.
- RCT: "Our results provide evidence opposing one of the main hypotheses of self-determination theory by showing that financial rewards are not necessarily associated with decreases in more internal forms of motivation when offered as part of a complex multicomponent intervention."
- RCT: "Individualized LGI diet consultations for overweight and obese pregnant women failed to make a significant difference in maternal or neonatal insulin resistance compared with the standard gestational diet consultation."
- RCT: Minimal Effect of High Compared with Low Dairy Consumption on Glucose Metabolism, Insulin Sensitivity, and Metabolic Flexibility in Overweight Adults.
- RCT: When Objective Accelerometry Measures are Used, No Significant Effects of a Brief Multimodal Intervention Integrated in Health Education Lessons to Increase Physical Activity and Reduce Sedentary Behavior Among Eighth Graders.
- RCT: "In healthy community-dwelling older men, exercise training and/or calcium-vitamin D fortified milk did not improve HR-QoL or depressive symptoms."
- Salivary α-amylase Copy Number is Not Associated with Weight Trajectories and Glycemic Improvements Following Clinical Weight Loss: Results From a 2-phase Dietary Intervention Study.
Basic
- Chronic Exposure to Green Light Aggravates High-fat Diet-induced Obesity and Metabolic Disorders in Male Mice.
- Myonectin Deletion Promotes Adipose Fat Storage and Reduces Liver Steatosis.
- Neuronal Calcium Sensor-1 (NCS-1) Deficiency is Associated with Obesity and Type 2 Diabetes in Mice.
- Siah2 Modulates Sex-Dependent Metabolic and Inflammatory Responses in Adipose Tissue to a High-Fat Diet Challenge.
- Synergistic Effects of DHA and Sucrose on Body Weight Gain in PUFA-Deficient Elovl2 -/- Mice.
- Effect of Propiconazole on the Lipid Metabolism of Zebrafish Embryos.
- Combined Exercise and Calorie Restriction Therapies Restore Contractile and Mitochondrial Functions in Skeletal Muscle of Obese–insulin Resistant Rats.
- Hyperadrenocorticism of Calorie Restriction Contributes to Its Anti‐inflammatory Action in Mice.
- Supplementation with Sodium Butyrate Modulates the Composition of the Gut Microbiota and Ameliorates High-Fat Diet-Induced Obesity in Mice.
- Resveratrol Treatment Ameliorates Leptin Resistance and Adiposity Programmed By the Combined Effect of Maternal and Post‐Weaning High‐Fat Diet.
Scientific Rigor & Scholarly Dialogue
- Retraction and Republication—Effect of a High-fat Mediterranean Diet on Bodyweight and Waist Circumference: A Prespecified Secondary Outcomes Analysis of the PREDIMED Randomised Controlled Trial.
- Maybe Combining Red Wine and Tea Doesn’t Kill Tumors After All.
- Rein in the Four Horsemen of Irreproducibility.
- What is the Best Housing Temperature to Translate Mouse Experiments to Humans?
Clinical
- RCT: Time-Restricted Feeding Improves Glucose Tolerance in Men at Risk for Type 2 Diabetes.
- RCT: Adiposity, Hepatic Triglyceride, and Carotid Intima Media Thickness During Behavioral Weight Loss Treatment in Antipsychotic-Treated Youth.
- Behavioural Weight Management Interventions for Postnatal Women: A Systematic Review of Systematic Reviews of RCTs.
- RCT: Closing the Gap: Results of the Multicenter Canadian Trial of Structured Transition in Young Adults with Type 1 Diabetes.
- Effects of a Mindfulness-Based Intervention on Distress, Weight Gain, and Glucose Control for Pregnant Low-Income Women: A Quasi-Experimental Trial Using the ORBIT Model.
- The Short-chain Fatty Acid Propionate Increases Glucagon and FABP4 Production, Impairing Insulin Action in Mice and Humans.
Children and Adolescents
- Reach of a Low-intensity, Multicomponent Childhood Overweight and Obesity Intervention Delivered in an Integrated Primary Care Setting.
- Preterm Birth as a Risk Factor for Metabolic Syndrome and Cardiovascular Disease in Adult Life: A Systematic Review and Meta-Analysis.
- Diet, Weight Gain, and Head Growth in Hospitalized US Very Preterm Infants: A 10-year Observational Study.
- Testing Bidirectional Associations Between Childhood Aggression and BMI: Results From Three Cohorts.
- Health Outcomes of Youth in Clinical Pediatric Weight Management Programs in POWER.
Surgery
- Genetic Determinants of Weight Loss After Bariatric Surgery. (pdf).
- Role of Adipose Tissue GLP-1R Expression in Metabolic Improvement After Bariatric Surgery in Patients with Type 2 Diabetes.
Drugs
- RCT: Effects of Inulin Propionate Ester Incorporated Into Palatable Food Products on Appetite and Resting Energy Expenditure.
- RCT: Comparing the Effects of Ipragliflozin Versus Metformin on Visceral Fat Reduction and Metabolic Dysfunction in Japanese Patients with Type 2 Diabetes Treated with Sitagliptin.
- "Among persons with weight loss of at least 5% after 1 year, those originally randomly assigned to metformin had the greatest loss during years 6 to 15."
Food & Diet
- Sustainable Diets, Food, and Nutrition: Proceedings of a Workshop.
- Meta-Analysis of RCTs of Red Meat Consumption in Comparison with Various Comparison Diets on Cardiovascular Risk Factors.
- RCT: Contrasting the Effects of 4 Low-calorie Sweeteners and Sucrose on Body Weight in Adults with Overweight or Obesity.
- Nutrition Therapy for Adults with Diabetes or Prediabetes: A Consensus Report.
- Extended Ketogenic Diet and Physical Training Intervention in Military Personnel.
- Should Viscous Fiber Supplements Be Considered in Diabetes Control? Results From a Systematic Review and Meta-analysis of RCTs.
- The Effect of Liquid Meal Replacements on Cardiometabolic Risk Factors in Overweight/Obese Individuals with Type 2 Diabetes: A Systematic Review and Meta-analysis of RCTs.
- RCT: Effect of a Lifestyle Intervention Program with Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial.
- RCT: Mediterranean Versus Western Diet Effects on Caloric Intake, Obesity, Metabolism, and Hepatosteatosis in Nonhuman Primates.
- Beverage Intake During Alternate-day Fasting: Relationship to Energy Intake and Body Weight.
Caloric Restriction
- Clinical Management of Intermittent Fasting in Patients with Diabetes Mellitus.
- A Review of the Molecular Pathways Mediating the Improvement in Diabetes Mellitus Following Caloric Restriction.
Exercise & Physical Activity
- A Body in Motion: Exercise and Cognition.
- Handgrip Strength, Inflammatory Markers and Mortality.
- The Panacea of Human Aging Calorie Restriction Versus Exercise.
Epidemiology
- Elucidation of Causal Direction Between Asthma and Obesity: A Bi-directional Mendelian Randomization Study.
- Obesity: Global Epidemiology and Pathogenesis.
- Relationship Between Individual Ventilatory Threshold and Maximal Fat Oxidation (MFO) Over Different Obesity Classes in Women.
- Imbalance in Obesity and Mental Health Among “little Emperors” in China.
- Temporal Changes in Obesity and Sleep Habits in Hong Kong Chinese School Children: A Prospective Study.
Psychology & Neuroscience
- Time is Overestimated in Obesity.
- Population Density is Beneficially Associated with 12-year Diabetes Risk Marker Change Among Residents of Lower Socio-economic Neighborhoods.
- Tasting with Your Eyes: Sensory Description Substitutes for Portion Size.
- Mood and Goal-Related Factors Associated with Early Non-Response in an Internet-Based Behavioral Weight Loss Program.
Economics & Sociology
- Modern Transference of Domestic Cooking Skills.
- “…we demonstrate that convenience store competition was associated with greater consumption of healthy foods and lower obesity rates.”
Policy Related
- Sleep-an Essential Component of Obesity Screening and Counseling: A Policy Analysis of the Affordable Care Act.
- Obesity prevention in children and young people: what policy actions are needed?
Equity and Disparities
- Utilizing a Board Game to Measure Family/Parenting Factors and Childhood Obesity Risk.
- RCT: Eat, Pray, Move: a Multilevel Church-Based Intervention to Address Obesity Among African Americans and Latinos.
- Racial and Ethnic Disparities in Adult Obesity in the United States: CDC's Tracking to Inform State and Local Action.
Stigma
- Shaping the Body Politic: Mass Media Fat-Shaming Affects Implicit Anti-Fat Attitudes.
- Psychometric Properties and Measurement Invariance of the Weight Self-Stigma Questionnaire and Weight Bias Internalization Scale in Children and Adolescents.
Intergenerational Effects
- Effects of Maternal and Grandmaternal Flea Infestation on Offspring Quality and Quantity in a Desert Rodent: Evidence for Parasite-mediated Transgenerational Phenotypic Plasticity.
- Comparing Pregnancy Outcomes and Loss Rates in Elective Twin Pregnancy Reduction to Ongoing Twin Gestations in a Large Contemporary Cohort. (pdf)
- Uncontrolled Eating During Pregnancy Predicts Fetal Growth.
Ecology, Evolution, & Energetics
- Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect Against Obesity.
- Polygenic Prediction of Weight and Obesity Trajectories From Birth to Adulthood.
- Commentary: Polygenic Risk Scores Expand to Obesity.
Methods
- Computational Models for the Mechanical Investigation of Stomach Tissues and Structure.
- Development of a Gold-standard Method for the Identification of Sedentary, Light and Moderate Physical Activities in Older Adults: Definitions for Video Annotation.
- Ethnicity-specific Cut-offs that Predict Co-morbidities: The Way Forward for Optimal Utility of Obesity Indicators.
Commentary
- Hold the Soda, Hold the Fat Shaming.
- Flummoxed By an Imaginary Concept of Healthy Food.
- It’s Just in Mice! This Scientist is Calling Out Hype in Science Reporting.
- Genetic Basis of Obesity Carries Weight.
- When Adding Sugar Doesn’t Add Up to Added Sugar.
- Why Obese Horses Need Both Diet and Exercise.
- The Data All Guilt-Ridden Parents Need.
- Genes are Not Destiny? What’s that Supposed to Mean?
- The Disturbing Links Between Too Much Weight and Several Types of Cancer.
- Counteracting Health Misinformation: A Role for Medical Journals.
- Kevin Hall: Common Ground on Ultra-Processed Foods?
General
- Tissue-specific Accumulation, Sexual Difference, and Maternal Transfer of Chlorinated Paraffins in Black-spotted Frogs.
- Bringing CAR-T Cancer Treatments to Solid Tumors with Help From Alpacas.
- Scientists Change Monkey Minds Using Low-intensity Ultrasound.
- Ten Simple Rules Towards Healthier Research Labs.
- Identifying Finding Sentences in Conclusion Subsections of Biomedical Abstracts.
- Metformin Induces the AP-1 Transcription Factor Network in Normal Dermal Fibroblasts.
- The Well-Meaning Bad Ideas Spoiling a Generation.
- Microbes in the Human Body Swap Genes, Even Across Tissue Boundaries, Study Indicates.
- Biologists Uncover New Rules for Cellular Decision-Making in Genetics.
- The FDA Just Approved a New Prescription Weight-Management Device. Here's How It Works.
- Food is Medicine—The Promise and Challenges of Integrating Food and Nutrition Into Health Care.
Video & Audio
- Video: In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data.
- Carbs, Calories, or Quality: What Matters Most for Weight Control? [Distinguished Lecturer Award Keynote, Canadian Obesity Summit - Dr. Kevin Hall].
Announcements
- IU Bloomington: With New Name, Prevention Insights Will Promote and Sustain Healthy Environments and Behaviors Nationwide.
- Advanced Therapies for Pediatric Obesity - October 4, 2019 @ University of Minnesota.
- Interdisciplinary Nutrition Sciences Symposium - July 24-25, 2019 @ Chapel Hill, NC.
- NORC of UAB Seeks Postdoctoral Fellows in Obesity Research.
- UAB Seeks Postdoctoral Fellows for Its AHA Strategically Focused Research Center– Obesity Network: Intergenerational Transmission of Obesity.
- Short Course: Causal Inference in Behavioral Obesity Research (7/29-8/2 @Bloomington, IN).
- Short Course: Mathematical Science in Obesity Research (6/3-7 @Baltimore, MD).