Featured

• Phenotypic Differences between People Varying in Muscularity.
• Polecat Body Size and Sex Ratio Change over Time: Impact of Invasive Competitor or Climate Warming?
• An Amish Founder Population Reveals Rare-Population Genetic Determinants of the Human Lipidome.

Headline vs Study

• Headline: Hiding Chocolate Eggs from the Entrance and End of Aisles in Supermarkets Would Cut Sales Threefold and Help Avoid the Post-Easter Weight Gain, Study Claims.
• Study: Nonrandomized Interrupted-Time-Series Analysis Shows Differences in Purchases of Chocolate Confectionery Products After Moving Them from Prominent Grocery Store Locations. Post-Easter Weight Gain Not Measured.
• Study Commentary: Controlled Study Shows How to Sell Less Easter Candy.

Contrary or Null Findings

• Meta-Analysis: "There is no evidence that [motivational interviewing] increases effectiveness of [behavioral weight management programs] in controlling weight."
• RCT: "neither traditional nor rest-redistribution resistance training protocols produced changes in cardiac autonomic modulation, sympathetic vasomotor tone, and cardiac baroreflex sensitivity of young healthy active individuals."
• RCT: "...a substantial increase of habitual protein intake above the currently recommended levels …in community-dwelling older adults…did not modulate the response to resistance training."
• RCT: No Significant Differential Effects of N-6 PUFA-Rich Soybean Oil, MUFA-Rich Olive Oil and Camellia Seed Oil on Weight and Cardiometabolic Profiles Among Chinese Women.
• RCT: In Ambulatory Patients with Heart Failure, a Dietary Intervention to Reduce Sodium Intake Did Not Reduce Clinical Events.
• RCT: Pre-Sleep Protein Supplementation After an Acute Bout of Evening Resistance Exercise Does Not Improve Next Day Performance or Recovery in Resistance Trained Men.
• "Eating breakfast daily was not associated with either higher or lower risk of T2DM in this cohort of older adults, while a later (after 09:00) daily first eating occasion time was associated with lower T2DM risk in participants with impaired fasting glucose at baseline."
• "...fasting leptin in 24-28 weeks of gestation ...does not differ between GDM and NGT and does not seem to be a good predictor for GDM."

Basic

• Fat Intake and Obesity-Related Parameters Predict Striatal BDNF Gene Expression and Dopamine Metabolite Levels in Cafeteria Diet-Fed Rats.
• The AR in Bone Marrow Progenitor Cells Protects Against Short-Term High Caloric Diet Induced Weight Gain in Male Mice.
• Inhibition of CXXC5 Function Reverses Obesity-Related Metabolic Diseases.
• IL-37 Isoform D Acts as an Inhibitor of Soluble ST2 to Boost Type 2 Immune Homeostasis in White Adipose Tissue.

Scientific Rigor & Scholarly Dialogue

• Letter: On the “Effects of Microbiota-Driven Therapy on Circulating Indoxyl Sulfate and P-Cresyl Sulfate in Patients with Chronic Kidney Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials”.
• Claim That Eating Breakfast Helps You Slim Down Doesn’t Hold Much Weight.
• Current World Health Organization Recommendation to Reduce Free Sugar Intake from All Sources to Below 10% of Daily Energy Intake for Supporting Overall Health Is Not Well-Supported by Available Evidence.
• Contrary to Our Expectations, Subsequent Treatment of PA-Induced Adipocytes with Nitrate Did Not Attenuate PA-Induced Lipid Accumulation or Senescence.

Clinical

• Systematic Review: Weight-Neutral Interventions in Young People with High BMI.
• RCT: Evaluating the Effect of Empagliflozin on Triglycerides in Adults with Obesity.
• RCT: Diabetes Remission in the Alliance of Randomized Trials of Medicine Versus Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D).

Children and Adolescents

• Tracking and Risk of Abdominal and General Obesity in Children between 4 and 9 Years of Age. The Longitudinal Childhood Obesity Study (ELOIN).
• Development of an Extended-Reality (XR)-Based Intervention to Treat Adolescent Obesity.
• Autism Spectrum Disorder Diagnosis and Other Child, Family, and Community Risk Factors for Obesity Among Children and Adolescents.

Surgery

• Preoperative Assessment of Obstructive Sleep Apnea in Bariatric Patients Using Polysomnography or Polygraphy.
• Long-Term Diabetes Improvement After Duodenal Exclusion in Zucker Diabetic Fatty Rats Is Associated with Prevention of Strain-Specific Pancreatic Remodeling and Increased Beta Cell Proliferation.
• Validity of Dual-Energy X-Ray Absorptiometry for Estimation of Visceral Adipose Tissue and Visceral Adipose Tissue Change After Surgery-Induced Weight Loss in Women with Severe Obesity.
• Impact of Bariatric Surgery on Unplanned Hospital Admissions for Infection.

Drugs

• Piecing Together Human Adult Comparative Pharmacokinetic Trials and Rodent Studies: What Happens to Drug Clearance in Obesity?
• Anti-Obesity and Anti-Hyperglycemic Effects of Meretrix lusoria Protamex Hydrolysate in Ob/Ob Mice.
• The Skinny on Treating Adult Obesity: Prescribing for Weight Loss.

Food & Diet

• Meta-Analysis: Effects of Exogenous Ketone Supplementation on Blood Glucose.
• Review: Antioxidant, Anti-Obesity, Nutritional and Other Beneficial Effects of Different Chili Pepper.
• RCT: The Effect of Hydroxy Citric Acid Supplementation with Calorie-Restricted Diet on Metabolic, Atherogenic and Inflammatory Biomarkers in Women with Non-Alcoholic Fatty Liver Disease.
• Dietary Fatty Acids Affect Learning and Memory Ability Via Regulating Inflammatory Factors in Obese Mice.
• High-Fat Diet Affects Measures of Skeletal Muscle Contractile Performance in a Temperature Specific Manner but Does Not Influence Regional Thermal Sensitivity [in Mice].
• One-Year Changes in Fruit and Vegetable Variety Intake and Cardiometabolic Risk Factors Changes in a Middle-Aged Mediterranean Population at High Cardiovascular Risk.

Caloric and Dietary Restriction

• Adherence to a Caloric Budget and Body Weight Change Vary by Season, Gender, and BMI: An Observational Study of Daily Users of a Mobile Health App.
• S-Adenosyl-L-Homocysteine Extends Lifespan Through Methionine Restriction Effects.
• Ramadan Diurnal Intermittent Fasting Is Associated with Attenuated FTO Gene Expression in Subjects with Overweight and Obesity.

Exercise & Physical Activity

• RCT: Effects of Reduced Sedentary Time on Cardiometabolic Health in Adults with Metabolic Syndrome.
• Meta-Analysis: The Effectiveness of Wearable Devices as Physical Activity Interventions for Preventing and Treating Obesity in Children and Adolescents.
• Whole-Body Cryostimulation Does Not Disturb the Homeostasis of the System in Physically Active Men - Pilot Study.
• Effect of Exercise on Body Composition Among Women with Ovarian Cancer.

Economics & Sociology

• Dissertation: The Individual and Environmental Determinants of Weight Status and Academic Achievement: A Multi-Level Analysis.
• Mediators of Differences by Parental Education in Weight-Related Outcomes in Childhood and Adolescence in Norway.
• Evaluating the Association between Socioeconomic Position and Cardiometabolic Risk Markers in Young Adulthood by Different Life Course Models.

Epidemiology

• Systematic Review: Impact of the First Year of COVID-19 on Obesity Risk Factors: A Pandemic Fueling a Pandemic.
• Trajectories of Infant Weight Gain from Birth to 12 Months and Adult Onset Coronary Heart Disease.
• Prenatal Exposure to Insecticides and Weight Trajectories Among South African Children in the VHEMBE Birth Cohort.
• Serum Lead Levels and Its Association with Overweight and Obesity.
• Obesogenic Environments and Cardiovascular Disease: A Path Analysis Using US Nationally Representative Data.

Psychology & Neuroscience

• The Effect of Functional Training on Level of Brain-Derived Neurotrophic Factor and Functional Performance in Women with Obesity.
• Using Event-Related Potentials to Study Food-Related Cognition: An Overview of Methods and Perspectives for Future Research.
• Is This Food Healthy? The Impact of Lay Beliefs and Contextual Cues on Food Healthiness Perception and Consumption.
• Decreased Excitability of Leptin-Sensitive Anterior Insula Pyramidal Neurons in a Rat Model of Compulsive Food Demand.
• Review: Developing Our Understanding of Nutrition in Depression.
• Review: The Influence of the Subcortex and Brain Stem on Overeating: How Advances in Functional Neuroimaging Can Be Applied to Expand Neurobiological Models to Beyond the Cortex.

Equity and Disparities

• Racial Differences in Diagnosis of Overweight and Obesity.
• Review: Kinesiology, Physical Activity, Physical Education, and Sports Through an Equity/Equality, Diversity, and Inclusion (EDI) Lens.

Stigma

• Sources of Weight Stigma and Adolescent Mental Health: From Whom Is It the Most Harmful?
• Destigmatizing Obesity and Overcoming Inherent Barriers to Obtain Improved Patient Engagement.
• Experienced Weight Stigma, Internalized Weight Bias, and Clinical Attrition in a Medical Weight Loss Patient Sample.

Policy Related

• Good Governance for Planetary and the Public's Health.
• U.S. Nutrition Assistance Program Participation and Childhood Obesity.

Intergenerational Effects

• Gestational Weight Gain and Patterns of Breastfeeding Among Patients with Class III Obesity.
• Effects of Low Protein-High Carbohydrate Diet During Early and Late Pregnancy on Respiratory Quotient and Visceral Adiposity.
• The Intersection of Maternal Metabolic Syndrome, Adverse Pregnancy Outcomes, and Future Metabolic Health for the Mother and Offspring.
• Review: Early Life Programming of Health and Disease: The Long-Term Consequences of Obesity in Pregnancy.

Ecology, Evolution, & Energetics

• Everything in Moderation or Moderating Everything? Nutrient Balancing in the Context of Evolution and Cancer Metabolism.
• Leptin Modulates Oocyte Maturation by a Central and a Direct Pathway in Zebrafish.

Methods

• Intraclass Correlation Coefficients for Weight Loss Cluster RCTs in Primary Care: The PROPEL Trial.
• Value and Challenges of Using Observational Studies in Systematic Reviews of Public Health Interventions.
• Systematic Review: Food and Nutrition Systems Dashboards.

Commentary

• Rates of Serious Flu-Related Illness Higher Among Patients with Diabetes.
• Healthy-Aging Ingredients: Can Fisetin Fight Zombie Cells?
• "Caloric Consumption Affects Caloric Restriction in Mice."
• Obesity in Horses Appears to Take a Heavy Toll on Their Heart – Study.
• Uncaring Healthcare That Fuels Obesity.
• Keeping an Eye Out for Opportunities in Challenging Times.
• How Sound are Recommendations to Cut Added Sugar?
• How Obesity Can Change the Immune System and Its Link to Allergic Inflammation.

General

• Beyond the Second Law.
• Preprint: Food Insecurity During COVID-19 in Children with End-Stage Kidney Disease: A Pilot Study.
• Podcast: Why Do We Die Without Sleep?
• How a Dwindling Caribou Herd Was Saved.
• The Genius of Fishing with Tidal Weirs.
• What’s New with Research Methods Resources: Stepped-Wedge Group RCTs and More.
• Mitochondria Double as Tiny Lenses in the Eye.
• Meta-Analysis: Association between Male Dimorphism and Fitness Outcomes in Humans.

Announcements

• Penn State Renames Building After Shirley Malcom, Who Continues to Inspire on a National Level.
• The Strategic Council for Research Excellence, Integrity, and Trust: Meeting 3.
• IU Bloomington School of Public Health Is Recruiting Tenure-Track Faculty in Every Department. A Sampling of Opportunities Is Here.