04/03/26
Featured
- Reducing the Strain Effect of Calorie Restriction.
- Podcast: Bimagrumab and Semaglutide: The BELIEVE Trial Results with Dr. Stephen Heymsfield.
- From the labs: Weaning, More Than a Change of Food: It Shapes a Life-Long, Healthy Gut.
- RCT: "Findings challenge the perception that red meat is broadly unsuitable for older adults" in "Effects of Minimally Processed Red Meat within a Plant-Forward Diet on Biomarkers of Physical and Cognitive Aging."
- Quadriceps Mitochondrial DNA Quantity, Quality, and Gene Expression After 2 Years of Calorie Restriction: Exploratory Results from the CALERIE Trial.
Corrigenda
Headline vs Study
- Headline: Nuclear War Fear? The Food That Protected Japanese People Against Atomic Bomb Radiation in Nagasaki.
- Study: Review of Miso and Radiation Injury, Cancer and Hypertension. Radiation Research All in Mice.
Contrary or Null Findings
- Metformin Blunts Vascular Insulin Sensitivity After Exercise Training in Adults at Risk for Metabolic Syndrome.
- RCT: "We did not find any difference in the QOL after a 12-week exercise intervention in patients with active IBD compared to standard care."
- RCT: No Effects on Adherence to Nutritional Recommendations (Except Protein Intake) by Patients Undergoing Cardiovascular Rehabilitation.
- RCT: "In conclusion, daily participation in an exercise countermeasure preserves thigh muscle volume during 2 weeks of bed rest in healthy older adults but is insufficient to mitigate muscle strength and total lean mass."
- RCT: "Sleep extension did not impact MVPA."
- RCT: No Effects of Acute Effect of Moderate-Intensity Aerobic Exercise on State Anxiety and Anger Symptoms Evoked by Aversive Stimuli in Young Women.
- RCT: "A behaviour change intervention added to standard maintenance stage cardiac rehabilitation did not improve physical activity or health outcomes."
- RCT: "This study demonstrated that the multitask training system did not confer additional benefits beyond aerobic exercise under a low-intensity, short-duration protocol in older adults, with no significant improvements in cognitive performance or frontopolar hemodynamic reactivity.”
Basic
- Ramulus Mori (Sangzhi) Alkaloids Attenuate Diet-Induced Obesity by Modulating Adipose Tissue Metabolic Programs.
- Intestinal Epithelial Peroxisome Proliferator-Activated Receptor γ Deficiency Exacerbates Insulin Resistance in Mice with Metabolic Dysfunction-Associated Steatohepatitis.
- Heat-Treated Culture-Dried Lactiplantibacillus plantarum L-14 Regulates Lipid Metabolism and Attenuates Diet-Induced Obesity in Adipose Tissue.
Scientific Rigor & Scholarly Dialogue
- Reanalyzing Castner et al. Confirms Most Conclusions, Reveals Additional Findings, and Detects Some Statistical Errors.
- Podcast: This Episode Does a Deep Dive Into a Study That Investigated the Combined Effects of the Drug Metformin and Various Exercise Training Intensities on Vascular Health.
Clinical
- Associations between Dietary Glycemic and Insulinemic Patterns and Eating Behavior in Adults: A Cluster-Based Analysis.
- Clinical Characteristics and Survival in Sarcopenic Obesity Defined by the Japanese Working Group on Sarcopenic Obesity Criteria Versus Existing Definitions in Older Adults: Findings from the Otassha Study.
- RCT: Magnesium Supplementation Did Not Reduce Serum Calciprotein Crystallization and Arterial Stiffness in Individuals with Type 2 Diabetes.
- RCT: Targeting Weight Loss and Blood Glucose Control with Oral Sodium Butyrate in Adults with Overweight/Obesity and with or Without Type 2 Diabetes.
- The Visceral Adiposity Index (VAI) as a Predictor for Metabolic Syndrome in a Sample of Older Adults with Obesity.
Children and Adolescents
- Meta-Analysis: Global Prevalence and Clinical Correlates of Obesity in Children and Adolescents with Type 1 Diabetes.
- Effectiveness of a School-Based Obesity Control Program Among Adolescents in Makkah.
- Review: Metabolic Disruption in Early Life: The Role of Endocrine Disruptors in Pediatric Obesity.
- Circadian Misalignment and Adolescent Obesity Risk Behaviors: Physical & Sedentary Activity, Dietary Intake, and Food Reward.
- Review: Digital Tools’ Effectiveness on Physical Activity Outcomes in Children and Adolescents.
Surgery
- Analysis of the Supportive Care Needs After Metabolic Bariatric Surgery in Germany Using an Adjusted Supportive Care Needs Survey- Short Form (SCNS-SF34).
- Risk Factors for Postoperative Pulmonary Complications in Gastric Carcinoma Patients Undergoing Surgery After Neoadjuvant Therapy.
- Meta-Analysis: Gastroesophageal Reflux Disease Outcomes After Sleeve Gastrectomy with One Anastomosis Transit Bipartition.
- Case Series: Obesity Surgery and Serious Psychiatric Conditions, Lessons Learned from 5 Patients.
- Pregnancy Outcomes After Metabolic Bariatric Surgery According to the Surgery-To-Conception Interval: A Multicentre Retrospective Cohort Study (MOMBARIS 2).
Drugs
- RCT: Exploratory Analysis of Liraglutide Effects on Obstructive Sleep Apnea and Health-Related Quality of Life in Individuals with Obesity and COPD.
- Real-World Cardiovascular Outcomes of Obesity Treatment with Tirzepatide Versus Semaglutide in Non-Diabetic Adults.
Food & Diet
- RCT: Almond Consumption Improves Inflammatory Profiles Independent of Weight Change in Adults with Obesity.
- RCT: Effect of Low-Carbohydrate vs Low-Fat Diet Intervention on Visceral Fat Estimated from Dual Energy X-Ray Absorptiometry in a 12-Month Trial.
Caloric and Dietary Restriction
- The Impact of Weight Cycling on Gut Microbiome Richness and Diversity in Female Rats.
- D, L-Buthionine-(S, R)-Sulfoximine Recapitulates the Anti-Obesity Effects of Sulfur Amino Acid Restriction Without the Associated Deleterious Effects on Bone in Male Mice.
- Review: Is the Timing of Eating Relevant for Weight Loss?
- Testicular Responses to Caloric Restriction and GLP-1 Treatment: Sirtuins, Acetylation, and Beyond [in Rats].
Exercise & Physical Activity
- Roseburia inulinivorans Increases Muscle Strength.
- Conserved Noncoding Cis Elements Associated with Hibernation Modulate Metabolic and Behavioral Adaptations in Mice.
- Review: Applying AI Tools for Monitoring Nutrition and Physical Activity in Populations with Obesity: Are We Ready?
- Physical Activity for Public Health in the 21st Century.
- Regulation of Physical Activity and Energy Expenditure Through Phf6 in the Medial Preoptic Area.
Economics & Sociology
- Exploring the Association between Women’s Autonomy and Overweight: Empirical Analysis in Côte D’Ivoire.
- Lived Experiences of Food-Related Emotional Expectancies Across Socioeconomic Groups in Adults with Overweight/Obesity.
- A Comprehensive Economic Assessment of the Burden of Obesity in Kuwait.
Epidemiology
- Application and Implications of New Global Definitions of Obesity: A Cross-Sectional Study of South African Women.
- Cross-Sectional Study: Assessment of Risk Factors for Overweight and Obesity in Teachers Population Living in a Large City.
- Postprandial Glucose Level Decreases and Appetite in Adults Without Diabetes.
Psychology & Neuroscience
- Neural Correlates of Illness Awareness in Obesity: An Exploratory Pilot fMRI Study.
- Obesity Accelerates Brain Ageing: A Multimodal Imaging Study.
- Adolescents Who have Overweight or Obesity Exhibit Weaker Spatial and Verbal Working Memory Compared with Healthy-Weight Peers.
Differential Population Circumstances, Exposures, Outcomes, and Effects
- Dissertation: Food Insecurity’s Influence on Obesity, Hypertension, and Diabetes in Rural Vermont and Adirondack New York.
- Metabolic Syndrome in Korean Older Adults: Prevalence, Determinants, and Nursing Implications.
- Bayesian Multilevel Analysis of Multimorbidity Among Women in Somalia: Prevalence, Patterns, and Determinants.
- Evaluation of Obesity Phenotypes from Childhood to Adolescence: Does Diet Quality in Childhood Matter? (PASE Study-Brazil).
Stigma
- Obesity-Related Beliefs, Concerns, and Stigmatizing Perceptions Among Adults Living with Obesity.
- RCT: Compassion-Focused Group Therapy Improves Depression, Emotional Eating, Self-Criticism and Shame in People Living with Severe Obesity.
- Internalized Weight Bias and Its Psychological Consequences.
Policy Related
- Toward a Comprehensive Definition of Diet Quality: Perspectives from the Italian Society of Human Nutrition (SINU).
- Discussion: Dietitians as System Builders: Advancing Equity, Sustainability and Health in Community Nutrition and Primary Care.
- Leveraging School Nutrition Environments Through Healthy Universal School Meals Laws to Improve Child Health and Academic Outcomes in the United States.
- Effects of the Dutch Jump-In School Nutrition Policy Intervention on Children’s At-School Dietary Behavior.
- RCT: Efficacy of Front-Of-Package Nutrient Labels Designed for Mandatory Implementation in the USA.
Intergenerational Effects
- Maternal Birth Weight and the Risk of Pregnancy Complications.
- Review: Epigenetic Legacy: The Role of Sperm miRNAs in the Paternal Inheritance of Diabetes and Obesity Development.
- Genetic Evidence for the Association between Schizophrenia and Obesity.
Ecology, Evolution, & Energetics
- Cannibalism Takes Major Bite Out of Young Blue Crabs, but the Shallows Offer a Refuge.
- Podcast: Evolutionary Psychiatry & Brain Health [with Nutrition] | Emily Deans, MD.
Methods
- Assessing Obesity Beyond BMI: Integrating Physiological and Functional Indicators of Impairment in National Health Surveillance.
- Machine Learning Prediction of Obesity Development in Children with Overweight Using Longitudinal Body Composition Data.
- Optimizing Preventive and Treatment Strategies for Obesity Reduction: A Mathematical Modeling and Cost-Effectiveness Analysis.
Mathematical and Quantitative
- Illustrating Poststratification Methods in Medical Claims Data: A Korean Example.
- Review: Six Entrenched Misconceptions About Meta-Analysis Models.
Commentary
- The American College of Sports Medicine (ACSM) Recently Updated Its Resistance Training Guidelines for the First Time Since 2009.
- Why Your Workout Isn’t Burning as Many Calories as You Think.
- Podcast: Does Unprocessed Red Meat Increase Diabetes Risk? - Gil Carvalho, PhD MD & Mario Kratz, PhD.
- Podcast: Optimal Protein Intake for Healthy Aging.
- When the Colossus of Obesity Collides with the Colossus of Lipoprotein(a): Implications for Primary Prevention of Atherosclerotic Cardiovascular Disease.
- Podcast: Dr. Sean Deoni - Feeding the Future: How Nutrition Shapes Brain Development and Learning.
- Human Milk Oligosaccharide Supplementation for Metabolic Health and Obesity: Potential Mechanisms, Current Evidence, and Research Priorities.
- "A study published in Science Advances by Baylor College of Medicine has uncovered a hidden brain pathway that helps explain how metformin lowers blood sugar, offering fresh insight into a medicine used for over six decades."
General
- Review: Designing and Implementing Real World Patient Reported Outcomes (RW- PROs) - Emerging Recommendations: A Good Practices Report of an ISPOR Task Force.
- Preprint: Day-To-Day Dietary Variation Shapes Overnight Sleep Physiology: A Target-Trial Emulation in 4.8 Thousand Person-Nights.
- Podcast: What Houses, Garbage, and Trucks Teach Us About Aging with Dr. Uri Alon.
- RCT: Children's Introduction to Novel Plant-Based Foods Through Varying Repeated Exposure Schedules.
- Searching for Shared Epigenetic Clocks: Evaluating Ultra-Conserved Markers in a De Novo Genome Assembly of the Albacore Tuna.
- Review: What Can We Learn from Bonobos and Bottlenose Dolphins About the Evolution of Between-Group Cooperation?
- Review: American College of Sports Medicine Position Stand. Resistance Training Prescription for Muscle Function, Hypertrophy, and Physical Performance in Healthy Adults: An Overview of Reviews.
- Letter: The Undue Burdens of Clinical Trial Participation: Implications for Equity, Diversity, and Inclusion.