Featured

• Critical Data at the Crossroads: National Health and Nutrition Examination Survey Faces Growing Challenges.
• Spatial Mapping of Mitochondrial Networks and Bioenergetics in Lung Cancer.
• The Combined Effect of Metformin and Mirabegron on Diet-Induced Obesity [In Mice]. (PDF)
• Fitness Correlates of Blubber Oxidative Stress and Cellular Defenses in Grey Seals (Halichoerus Grypus): Support for the Life-History-Oxidative Stress Theory from an Animal Model of Simultaneous Lactation and Fasting.

Headline vs Study

• Headline: Coffee Could Slash Obesity, Type 2 Diabetes Risks: Study.
• Study: Mendelian Randomization Study - Higher Genetically Predicted (not Measured) Plasma Caffeine Concentrations Were Associated with Lower Body Mass Index, Whole Body Fat Mass (but Not Fat-Free Mass), and Type 2 Diabetes. Coffee Consumption Not Measured.

Contrary or Null Findings

• RCT: "No significant effects of the intervention were observed" in "Effect of an educational intervention on diet and physical activity among school-aged adolescents in Delhi..." (PDF)
• Binge Drinking Does Not Appear to Have an Adverse Effect on Non-Alcoholic Fatty Liver Disease: Findings from a Study of Four First Nations Communities.
• A High-Fat Diet Changes Placental Morphology but Does Not Change Biochemical Parameters, Placental Oxidative Stress or Cytokine Levels.
• Obesity Does Not Modify the Effect of Continuous Positive Airway Pressure on Insulin Resistance in Adults with Obstructive Sleep Apnoea.
• Lowered Muscle Glycogen Reduces Body Mass with No Effect on Short-Term Exercise Performance in Men.
• Contrary to Our Hypothesis, Maternal HF Diet Reduced AEA and 2-AG in Breast Milk.
• RCT: "Contrary to expectations, post-exercise meals were less likely to be unhealthy (relative to mixed) than were random meals from non-exercise days (OR = 0.63, p = .011), and that participants ate proportionally fewer unhealthy meals on exercise days compared to non-exercise days (b = -4.27, p = .004)."
• "Among adults with obesity and NAFLD, TRE did not produce additional benefits for reducing IHTG content, body fat, and metabolic risk factors compared with DCR."

Basic

• Estradiol Regulates Leptin Sensitivity to Control Feeding Via Hypothalamic Cited1.
• Promotion of Healthy Adipose Tissue Remodeling Ameliorates Muscle Inflammation in a Mouse Model of Sarcopenic Obesity.
• Monocarboxylate Transporter 1 in the Liver Modulates High-Fat Diet-Induced Obesity and Hepatic Steatosis in Mice.
• Estrogen Contributes to the Sex Difference in the Occurrence of Senescence-Related T Cells During the Development of Visceral Adipose Tissue Inflammation.
• Gut Microbiota Mediates the Anti-Obesity Effect of Intermittent Fasting by Inhibiting Intestinal Lipid Absorption.
• Protein-Metabolite Interactomics of Carbohydrate Metabolism Reveal Regulation of Lactate Dehydrogenase.

Scientific Rigor & Scholarly Dialogue

• Article: Effectiveness of Wearable Technology to Optimize Youth Soccer Players’ Off-Training Behaviour and Training Responses: A Cluster-Randomized Trial.
• Letter: Individually Randomized Trial Mislabeled as a Cluster Randomized Trial. Comment On: “Effectiveness of Wearable Technology to Optimize Youth Soccer Players’ Off-Training Behaviour and Training Responses: A Cluster-Randomized Trial”.
• Article: Approximately Half of Total Protein Intake by Adults Must Be Animal-Based to Meet Nonprotein, Nutrient-Based Recommendations, with Variations Due to Age and Sex.
• Letter: No Nutritional Lessons Can Be Learned from a Misspecified and Overrestricted Model with No Sensitivity Analysis.
• Response: Reply to F Mariotti et al.
• Retraction: Examination of Two New Technologies to Assess the Diet of Woodland Caribou: Video Recorders Attached to Collars and DNA Barcoding.

Clinical

• Meta-Analysis: Effects of Very Low-Carbohydrate Ketogenic Diets on Lipid Profiles in Normal Weight Adults.
• Differences between HbA1c and Glucose-Related Variables in Predicting Weight Loss and Glycaemic Changes in Individuals with Overweight and Hyperglycaemia – the PREVIEW Trial.
• Association of Changes in Neural Targets and Dietary Outcomes Among Patients with Comorbid Obesity and Depression: Post Hoc Analysis of ENGAGE-2 Mechanistic Clinical Trial.
• Mobile Health Lifestyle Intervention Program Leads to Clinically Significant Loss of Body Weight in Patients with NASH.
• Overlapping and Distinct Relationships between Hedonic Hunger, Uncontrolled Eating, Food Craving, and the Obesogenic Home Food Environment During and After a 12-Month Behavioral Weight Loss Program.

Children and Adolescents

• RCT: The Effect of a Preconception and Antenatal Nutritional Supplement on Children's BMI and Weight Gain over the First 2 Years of Life.
• RCT: The Effects of Prebiotics on Gastrointestinal Side Effects of Metformin in Youth-Onset Type 2 Diabetes.
• City Features Related to Obesity in Preschool Children in 159 Cities in Six Latin American Countries.
• Thirty-Year Follow-Up of the NICHD Study of Early Child Care and Youth Development (SECCYD): The Challenges and Triumphs of Conducting In-Person Research at a Distance.
• Association of a Primary Care-Based Mobile Food Pantry with Child Body Mass Index: A Propensity Score Matched Cohort Study.
• Meteorin-Like Levels are Associated with Active Brown Adipose Tissue in Early Infancy.

Surgery

• How Soon Do Depression and Anxiety Symptoms Improve After Bariatric Surgery?
• Review: Metabolic and Bariatric Surgery in Adolescents.

Drugs

• Chemo-Structural Diversity of Anti-Obesity Compound Database.
• Increasing Inosine/decreasing ENT1: Promising Strategies for Anti-Obesity Therapy.
• A Comparative Evaluation of Propranolol Pharmacokinetics in Individuals with Obesity Versus Ideal Weight: A Blueprint Towards a Personalised Medicine.
• Anti-Obesity Effects of Metformin: A Scoping Review Evaluating the Feasibility of Brown Adipose Tissue as a Therapeutic Target.
• Commentary: Will the Ozempic Era Change How We Think About Being Fat and Being Thin?

Food & Diet

• Beneficial Effect of Vitamin D on Non-Alcoholic Fatty Liver Disease (NAFLD) Progression in the Zebrafish Model.
• Associations between Household Frequency of Cooking Dinner and Ultraprocessed Food Consumption and Dietary Quality Among US Children and Adolescents.
• Optimal Dietary Patterns for Prevention of Chronic Disease.
• Combined Intake of Sugar-Sweetened Beverages and Sugar-Containing Ultra-Processed Foods Is Associated with an Increase in Body Mass Index During Early Childhood.
• Systematic Review and Meta-Analysis: Primary Prevention of Cardiovascular Disease in Women with a Mediterranean Diet.

Caloric and Dietary Restriction

• Four Anti-Aging Drugs and Calorie-Restricted Diet Produce Parallel Effects in Fat, Brain, Muscle, Macrophages, and Plasma of Young Mice.
• Effects of Parental Dietary Restriction on Offspring Fitness in Drosophila Melanogaster.

Exercise & Physical Activity

• Criterion-Related Validity and Reliability of the 2-Km Walk Test and the 20-M Shuttle Run Test in Adults: The Role of Sex, Age and Physical Activity Level.
• Associations between Accelerometer-Measured Physical Activity and Fecal Microbiota in Adults with Overweight and Obesity.

Economics & Sociology

• The Effect of Retirement on Obesity in Women: Evidence from China.
• A Spatial Analysis of Food Insecurity and Body Mass Index with Income and Grocery Store Density in a Diverse Sample of Adolescents and Young Adults.
• Socioeconomic and Clinical Factors Associated with Excessive Gestational Weight Gain.

Epidemiology

• Polygenic Risk Scores Enhance Prediction of Body Mass Index Increase in Individuals with a First Episode of Psychosis.
• Impact of Overweight and Obesity on U.S. Renal Cell Carcinoma Incidence Trends (1995–2018).
• Premature Cardiovascular Disease Mortality with Overweight and Obesity as a Risk Factor: Estimating Excess Mortality in the United States During the COVID-19 Pandemic.
• Obesity and Adverse Childhood Experiences in Relation to Stress During the COVID-19 Pandemic: An Analysis of the Canadian Longitudinal Study on Aging.
• The Role of Obesity in Sarcopenia and the Optimal Body Composition to Prevent Against Sarcopenia and Obesity.
• Body Fat Distribution in Lean Individuals with Metabolic Abnormalities.

Psychology & Neuroscience

• Effect of Financial Incentives and Default Options on Food Choices of Adults with Low-income in Online Retail Settings.
• RCT: Association of Changes in Neural Targets and Dietary Outcomes Among Patients with Comorbid Obesity and Depression: Post Hoc Analysis of ENGAGE-2 Mechanistic Clinical Trial.
• Review: Brain Functional and Structural Magnetic Resonance Imaging of Obesity and Weight Loss Interventions.

Equity and Disparities

• American Indian/Alaska Native Birth and Maternal Health Outcomes in Louisiana: Investigating Regional Disparities.
• Socioeconomic Disparities in Health Outcomes in the United States in the Late 2010s: Results from Four National Population-Based Studies.

Stigma

• Commentary: Anecdotes and Studies of Lived Experiences with Obesity.
• Adolescents' Self-Perceived Weight and Metabolic Syndrome.

Policy Related

• Time-Varying Food Retail and Incident Disease in the Cardiovascular Health Study.
• Racial, Ethnic, and Gender Differences in the Association between Higher State Minimum Wages and Health and Mental Well-Being in US Adults with Low Educational Attainment.
• Review: Barriers and Facilitators Related to the Adoption of Policies to Reduce Ultra-Processed Foods Consumption.
• From Multiple Streams to a Torrent: A Case Study of Food Policymaking and Innovations in New York During the COVID-19 Emergency.
• Understanding School Food Systems to Support the Development and Implementation of Food Based Policies and Interventions.

Intergenerational Effects

• Utility of in Vivo Magnetic Resonance Imaging Is Predictive of Gestational Diabetes Mellitus During Early Pregnancy.
• Associations of Maternal Pre-Pregnancy Body Mass Index and Gestational Weight Gain with Risk of Offspring Neurodevelopment at 2 Years: A Chinese Birth Cohort Study.

Ecology, Evolution, & Energetics

• Forest Fragmentation and Developmental Stability of Wood Mice Apodemus Sylvaticus: A Food-Mediated Effect?
• Review: The Fire of Evolution: Energy Expenditure and Ecology in Primates and Other Endotherms.

Methods

• Development of the Italian Clinical Practice Guidelines on Bariatric and Metabolic Surgery: Design and Methodological Aspects.
• Estimation of Salt Intake in Normotensive and Hypertensive Children: The Role of Body Weight.

Commentary

• Metamorphosis: The Making of a Maggot Brain.
• A Cluster of Unreliable Prevention Studies.
• Feeding Ourselves Without Eating the Planet.
• Obesity & Eating Disorders, Speculation & Data.
• Low Sex Hormones May Increase Likelihood for Transition to Diabetes Among Hispanic Adults.
• Limitations of the Food Compass Nutrient Profiling System.
• Population-Specific Diet Quality Scores in Nutritional Epidemiology.
• Obesity Won’t Be Solved by Health Policy Alone.

General

• Where Did Spiders Get Their Venom?
• Telecaregiving for Dementia: A Mapping Review of Technological and Non-Technological Interventions.
• Mathematical Modeling of Eicosanoid Metabolism in Macrophage Cells: Cybernetic Framework Combined with Novel Information-Theoretic Approaches.
• Y Chromosome-Linked Variation Affects Locomotor Activity in Male Drosophila Melanogaster and Is Robust to Differences in Thermal Environment.
• Does More Money Make Us Happier?
• Social Media Use May Not Be as Bad as Some Suggest: Implication for Older Adults.
• Lipids Called Ceramides May Be Better Predictors of Cardiovascular Problems Than Cholesterol.
• A Time-Series Analysis of Blood-Based Biomarkers Within a 25-Year Longitudinal Dolphin Cohort.
• "This means drawing a clear line between the generation of science and the promotion of our values."
• Dogs and Cats Could Be Passing on Drug-Resistant Bugs to Owners.

Video & Audio

• Dr. Satchin Panda: Intermittent Fasting to Improve Health, Cognition & Longevity.
• Podcast: Top Ten Obesity Myths.

Announcements

• April 19 - TOS Grand Rounds: Pediatric Obesity Interventions - Caveat Emptor.
• Registration Is Open for NUTRITION 2023! Join the Nutrition Community in Boston, MA This July.
• "The Indiana Clinical and Translational Sciences Institute (CTSI) has secured nearly $38 million in renewed funding from the National Institutes of Health for the next seven years—the fourth consecutive successful grant submission for the statewide research enterprise."
• Registration Now Open: Strengthening Causal Inference in Behavioral Obesity Research, June 26th to June 30th in Person at the IU School of Public Health-Bloomington.
• Save the Date: The Mathematical Sciences in Obesity Research, July 31st to August 4th in Person at the IU School of Public Health-Bloomington.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Collaborative Skills to Join an Interdisciplinary Team of Researchers Focused on Design, Analysis, Interpretation, and Reporting of Clinical Trials, Epidemiologic Analyses, Model Organism Studies, and Meta-Research, All in the Context of Obesity, Nutrition, or Aging Research, with an Emphasis on Promotion of Rigor, Reproducibility, and Transparency.
• IU School of Public Health-Bloomington Invites Applications for a Research Associate with Strong Collaborative Skills to Join an Interdisciplinary Team of Researchers Focused on Design, Analysis, Interpretation, and Reporting of Clinical Trials, Epidemiologic Analyses, Model Organism Studies, and Meta-Research, All in the Context of Obesity, Nutrition, or Aging Research, with an Emphasis on Promotion of Rigor, Reproducibility, and Transparency.
• IU Bloomington’s School of Public Health is Recruiting Tenure-Track Faculty at every rank in every department. Come Join Us!