Featured

• Suggested Improvements to Clarity of Glucagon-Like Peptide-1 Receptor Agonist Publications.
• RCT: The Effects of 31-Day Exogenous Ketone Consumption on Running Performance, Cognitive Function, Metabolism, Body Composition, Hemodynamics, and Mood in Recreational Runners.
• Inverse Associations of Serum Total Omega-6 Polyunsaturated Fatty Acids and Linoleic Acid with Biomarkers of Inflammation: A Cross-Sectional Analysis.
• Understanding ‘Food Noise’ in the Age of GLP-1s.

Headline vs Study

• Headline: Eating Vegetables First Boosts Mental Capital: A-CHILD.
• Study: Association (Not Necessarily Causation) between Reportedly Eating Vegetables First at the Meal and Reported Resilience and Self-Esteem.

Contrary or Null Findings

• RCT: "The 9-month online bone-strengthening exercise intervention did not increase the femoral neck aBMD Z-score..."
• RCT: No Significant Effects of Curcumin and Epigallocatechin-3-Gallate Supplementation on Serum Brain-Derived Neurotrophic Factor and Mood Disturbance in Adults.
• RCT: "Catechin plus inulin for 12 weeks did not reduce visceral fat..."
• RCT: "Among adults with newly diagnosed SARS-CoV-2 infections, vitamin D3 supplementation did not significantly change the 4-wk cumulative incidence of healthcare utilization or COVID-19-related outcomes compared with placebo."
• RCT: No Effect on Change in Ambulatory Function in Functional Cycling Ergometry with or Without Electrical Stimulation in Individuals with Secondary Progressive Multiple Sclerosis.
• RCT: Null Effects with Short-Term Supplemental Oxygen Therapy on 6-Min Walk Distance in Highlanders at Risk for Pulmonary Hypertension.
• RCT: "Exercise-based prehabilitation had little or no effect on long-term time spent at home..."
• RCT: "In individuals with obesity, 4.5-hour intravenous infusion of oxytocin causing supraphysiological plasma concentrations of ~400 pg/mL has no effect on ad libitum food intake, appetite sensations, plasma glucose levels, circulating concentrations of glucose and appetite-regulating hormones, or gastric emptying."

Basic

• Casein- and Soy-Based High-Protein Diets Differentially Affect Insulin Resistance and Adipose Tissue Advanced Glycation End Product Accumulation in Obese Diabetic Mice.
• Bioengineered ROS-Tolerant Probiotic Reshapes Gut Microbiota-Host Axis to Ameliorate Type 2 Diabetes in Male Mice.
• Spatial Lipidomic Combining DESI Imaging and LESA Mass Spectrometry to Evaluate Metabolic Alterations in Obese Zebrafish.
• 3′-Hydroxypterostilbene Alleviates Obesity and Lipoprotein Metabolism Dysregulation by Reshaping Gut Microbiota in High-Fat Diet-Induced Obese Mice.
• High-Intensity Intermittent Training Promotes Adipose Tissue Browning Via the IL-27/p38 MAPK–PGC-1α Signaling Pathway in Diet-Induced Obese Rats.

Scientific Rigor & Scholarly Dialogue

• PubPeer Comments On: The Effects of Omega-3 Supplementation on Stress, Anxiety, Depression, Sleep Quality, and Everyday Memory in Individuals with Psychological Distress: A Randomized, Double-Blind, Placebo-Controlled Trial.
• Retraction: Longitudinal Data from the KETO-CTA Study: Plaque Predicts Plaque, ApoB Does Not.
• Video: Statistical Dissection of 'Keto-CTA' Study.
• Reporting Quality of Randomized Controlled Trials Examining Nutritional Interventions in Mild Cognitive Impairment.

Clinical

• Joint TOS/OMA/OAC Expert Guidance Statement on the Pharmacological Management of United States Adults with Overweight or Obesity Using the GRADE Approach.
• Efficacy of Dietary Interventions for Functional Constipation.

Children and Adolescents

• Trends in Obesity, Overweight, and Attempted Weight Loss Among United States High School Students.
• Risk Factors of Overweight/Obesity Among Children Aged 48-59 Months in Wajo, South Sulawesi.
• Review: Effectiveness of Interventions During Early Childhood to Prevent Overweight and Obesity.
• Soy Protein-Based Infant Formula Feeding Association with Adolescent Growth, Body Composition, Cardiometabolic Health, and Pubertal Development in Comparison with Cow's Milk-Based Infant Formula and Human Milk Feeding.

Surgery

• Endoscopic Sleeve Gastroplasty: 6-Year Outcomes in 1,377 Patients.
• Bariatric Surgery in Adults with Type 1 Diabetes and Obesity: A 3-Year Observational Matched Cohort Study.

Drugs

• Anti-Obesity Drugs and Emerging Therapies.
• Pharmacologic Treatment of Obesity in Adults: Standards of Care in Overweight and Obesity.

Food & Diet

• RCT: Exposure to Low-Sweet Snacks and Caregiver Nutritional and Dental Health Education Lowered Children’s Added Sugar Intake.
• Ultraprocessed Foods Consumption and Risk of Preeclampsia.
• Independent Effects of Whey Protein and Alkali Supplementation on Muscle Health in Healthy Older Adults.

Caloric and Dietary Restriction

• RCT: Effects of Short-Term Dietary Calorie Restriction Combined with Aerobic Exercise on Systemic Inflammation in Individuals with Overweight or Obesity and Knee Osteoarthritis.
• The Effects of Time-Restricted Eating on Energy Balance Regulation in Adults with Overweight/Obesity and Type 2 Diabetes.

Exercise & Physical Activity

• Predictive Value of Physical Literacy Measures for Cardiometabolic Risk in Adolescents with Abdominal Obesity: An Exploratory Study.
• Examining Physical Activity and Obesity Patterns in Adult Patients at a Mission-Based Hospital Outpatient Clinic in Southwest Nigeria: A Cross-Sectional Study.

Economics & Sociology

• Impact of Socioeconomic Status on Dietary Intake in Adults Aged 60 and Over, in Northwestern Spain.
• Preprint: Impact of Socioeconomic Status on Cardiometabolic Multimorbidity Progression Trajectories: A Multi-State Model Analysis Based on Three Prospective Cohort Studies.

Epidemiology

• Trends and Projections of Overweight and Obesity Among Midlife Women in the United States, 1990-2050.
• Review: Dietary Transitions and the Rising Global Burden of Chronic Kidney Disease: Insights from Nutritional Epidemiology.
• Metabolic Syndrome and Its Individual Components but Not MASLD are Associated with Advanced Fibrosis in Primary Biliary Cholangitis.
• Prevalence of Overweight and Obesity in the Era of CFTR Modulators in Patients with Cystic Fibrosis.

Psychology & Neuroscience

• Dietary Choline and Betaine Intake and 2-Year Changes in Cognitive Function in Older Adults with Overweight or Obesity and Metabolic Syndrome.
• Chronic High-Carbohydrate and High-Fat Diet-Induced Metabolic Syndrome Leads to Adrenal Dysfunction, Altered Dendritic Morphology in Limbic Regions, and Anxiety-Like Behaviors in Male Rats.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Redlining and Prevalent Obesity, Hypertension, and Diabetes in GuLF Study Participants.
• Socioeconomic Inequalities in Cardiometabolic Health Among United States Adults Using NHANES Data.

Stigma

• The Burden of Bias: Patient Experiences and Providers' Perspectives on Weight Bias.
• Weight Stigma from Close Others May Drive Reduced Adherence to Physical Activity and Nutrition Recommendations During Pregnancy and Postpartum.
• Attitudes and Behaviors of Pediatric Surgical Nurses Toward Pediatric Patients with Obesity in China.

Policy Related

• Commentary: The Impact of the United States’ Distancing from the UN and Withholding WHO Funding on Maternal and Child Health and Nutrition in the Latin America & Caribbean Region.
• NIH-FDA Nutrition Regulatory Science Workshop: Advancing Research and Policy.
• Systematic Review: Effects of Dual Front-Of-Pack Nutrition and Sustainability Labelling on Consumer Understanding, Purchase Intentions, Food Choices and Willingness to Pay.
• Valid and Reliable Questionnaire for Assessing Nutrition and Physical Activity Practices in Early Care and Education.

Intergenerational Effects

• Longitudinal Association between Human Milk Macronutrient Intake and Infant Growth Throughout the First 8.5 Months of Life.
• RCT: Preconception Micronutrient Supplementation Positively Affects Offspring Perceptual Reasoning at 10-11 Years of Age.

Ecology, Evolution, & Energetics

• Preprint: Mating-Dependent Lifespan Cost of Sterol Depletion in Male Drosophila Melanogaster.
• Perspective: Nutrient Bioavailability Is the Missing Ingredient Connecting Food Systems to Environmental Sustainability.

Methods

• Predictive Value of Traditional and Novel Obesity Indices for Stroke and Its Subtypes Across Sexes and Glucose Status.
• Obesity Risk Prediction Using Explainable Stacked Machine Learning with Lime Insights.
• Machine Learning-Based Identification of Abnormal Functional Connectivity in Obesity Across Different Metabolic States.

Commentary

• Can Ice Cream Be Healthy? What Recent Studies Actually Show.
• Obesity Medicines are Shaking Up the Way We Get Prescription Drugs.
• European Policies on Child Obesity Prevention, Health Promotion and Responsive Parenthood Within Joint Action Health4EUKids.
• Podcast: The Limits of Nutrition Coaching: Red Flags We Can't Ignore.
• Podcast: A Food Scientist Processes Nova and UPFs, Red-Hot Food Dye Substitutes, What’s Next for America’s Dietary Guidelines?
• The GLP-1 Paradox in Colorectal Cancer.
• Do Commercial Airline Policies for Passengers with Obesity Carry Enough Weight?
• Press Release: Cadrenal Therapeutics Highlights CAD-1005 Preclinical Data Supporting 12-LOX Inhibition for Obesity and T2D.
• Let Us Strive for Creative Solutions in Childhood Obesity Prevention & Intervention Research.

General

• Cardiorespiratory Fitness Is Differentially Associated with Motor Cortex Laterality in Middle-Aged and Older Adults.
• Eye-Opening Research: Greenland Sharks Maintain Vision for Centuries Through DNA Repair Mechanism.
• Review: American College of Sports Medicine Position Stand. Resistance Training Prescription for Muscle Function, Hypertrophy, and Physical Performance in Healthy Adults.
• RCT: Comparative Efficacy and Pharmacokinetic Parameters of Micronized Creatine Monohydrate (KleanCREATINE) in Active Men.
• Misregulated Alternative Splicing in Endometriosis: A Role for Aberrant mRNA Variants in Endometriotic Cell Growth.
• Preprint: Epigenetic Clocks of Biological Aging and Cognitively Healthy Longevity: The Women's Health Initiative Memory Study.
• Trustworthiness and Transparency Features Were Less Frequent in Randomized Trials Presenting Large Effects for Continuous Outcomes in Abstracts.
• Downregulation of Organ-Derived Activin a Attenuates Muscle Atrophy and Intramuscular Fat Infiltration in Cancer Cachexia Mice.

Announcements

• April 9 - Online Veda R. And Buford Nichols Jr. Lectureship - Gökhan S Hotamisligil - Regulation of Subcellular Molecular Architecture and Organelle Function in Health and Disease. (pdf)
• Call for Abstracts for ObesityWeek 2026.
• Webinar: Understanding the Media: A Starter Guide for Scientists. Tuesday, March 24, 2-3 P.m. ET.
• Director of Body Composition Sought in Division of Nutrition, US Department of Agriculture (USDA) Agricultural Research Service (ARS) Children’s Nutrition Research Center (CNRC), in the Department of Pediatrics at Baylor College of Medicine and Texas Children's Hospital.