Featured

• Perspective: Fat Reduction Campaigns and Their Impact on Young Children-The Root Cause of the Obesity Epidemic?
• Overcoming Impasse in Nutrition Science.
• Creatine and Cognition in Aging: A Systematic Review of Evidence in Older Adults.
• The S100A8/A9 Complex Promotes Food Intake and Prevents Adipose Tissue Loss During Cancer Cachexia in Mice.
• RCT: Bimagrumab Plus Semaglutide Alone or in Combination for the Treatment of Obesity.

Headline vs Study

• Headline: Study of 30,000 Shoppers Reveals Hidden Environmental Cost of Treat Foods.
• Study: Hypothetical Transition in Protein Sources for Sustainability Dimensions Based on Estimated Environmental Impact from Purchase Data. Nothing Hidden. 'Treat Foods' Include Things Like Coffee and Tea.

Contrary or Null Findings

• "This large prospective cross-sectional study found weak and inconsistent associations between the gut microbiome and premalignant colorectal neoplasia, with no robust microbial signatures. Findings suggest that previously reported microbial shifts may emerge later in disease progression, potentially as a consequence rather than a cause of CRC."
• Preprint: Large Increases in Resistance Training Volume Do Not Impair Skeletal Muscle Hypertrophy or Anabolic-Catabolic Molecular Signalling in Trained Individuals.
• RCT: No Differential Effect of a Chilean Diet Supplemented with Gevuina avellana molina Versus a Low-Fat Diet on Cardiometabolic, Oxidative Stress, and Inflammatory Biomarkers in Chilean Adults with Hypercholesterolemia.
• RCT: "Nevertheless, there were no significant differences between the two training groups in the mean values of SIRT1, NO, or systolic blood pressure..." in “Effects of low-load blood flow restriction resistance training on Sirtuin-1 and endothelial-related biochemical markers in men with type 2 diabetes.”
• RCT: "Based on this early terminated trial, a high-energy strategy for early nutrition in pancreatitis does not decrease mortality/severity, but potentially increases organ failure and pain relapse rate."
• RCT: "These findings suggest that supplementation with isolated leucine supplementation alone is insufficient to counteract cancer-related muscle waste and should be investigated as part of multimodal interventions addressing nutrition, inflammation, and physical activity." (pdf)
• RCT: "A 12-week run-walk training did not alter systemic CRP, TNF-α, or IL-8 in adults with chronic LBP. Improvements in pain intensity were not associated with changes in these inflammatory markers."
• RCT: Red rooibos "did not attenuate the changes to body composition, metabolic, or movement outcomes observed in the OVX (ovariectomized) group" [in mice].

Basic

• Aged Male Mice Remain Glucose Tolerant Despite Increased Energy Storage Efficiency Favoring Diet-Induced Obesity.
• Evexomostat (SDX-7320), a Methionine Aminopeptidase Type 2 Inhibitor, Stimulates Weight Loss and Inhibits Obesity-Accelerated Tumor Growth.
• Targeting COL6A3-C5 with Nigericin Suppresses Endotrophin Formation and Enhances Insulin Sensitivity in Obesity.
• Gpc3 Selectively Suppresses Subcutaneous Adipogenesis in Diet-Induced Obesity.
• GPR146 in Adipose Tissue Drives Adipose-Liver Crosstalk and Promotes Hepatic Steatosis in Mice.
• Glucagon Promotes Net Hepatic Glycogen Repletion Following Meal Ingestion.

Scientific Rigor & Scholarly Dialogue

• Podcast: New Study Shows Twice as Much Volume Doesn't Cause Extra Muscle Growth (Dissection of First Paper Under 'Contrary or Null Findings').
• Podcast: Why Nutrition Science Is Stuck — and How to Fix It | David Ludwig, MD, PhD.
• Podcast: Why Do Omega-3 Trials Show Mixed Results?
• Perspective: Guiding Principles for Science-Based Food Classification Systems Focused on Processing and Formulation.
• Editorial: Evolution of Food Classification Systems and Assessing Diet Quality.
• Podcast: Why Most Longevity Advice Gets Weight and Exercise Wrong.

Clinical

• Review of the Use of Digital Therapeutics (DTx) for Obesity Treatment: Towards a Psychological Phenotyping?
• Muscle Movement and Metabolism: Exercise and Skeletal Muscle as Mediators of Health. A Report from the 26th Annual Harvard Nutrition Obesity Symposium, 2025.

Children and Adolescents

• Does Childhood Obesity Foreshadow a Future Time-Bomb of Early and More Aggressive Cancers?
• Predicting Rapid Weight Gain in Six-Month-Old Infants: An Exploratory Modeling Study.
• Meta-Analysis: Effects of Family-Based Intervention for Childhood Obesity on Parental and Offspring Outcomes.
• Monitoring Growth and Body Composition in Children with 3D Optical Imaging.

Surgery

• Feasibility and Outcomes of Robotic Colorectal Cancer Surgery in Patients with High BMI.
• Review: Transplant Hepatology: New Epidemiology and Indications.
• Global Research Trends on Endoscopic Bariatric Surgery: Bibliometric Analysis over Past 2 Decades.
• Intravenous Sedation of a Patient with Morbid Obesity and Severe Sleep Apnea Syndrome for Dental Treatment.

Drugs

• Glucagon-Like Peptide-1 Receptor Agonist Switching and Treatment Persistence in Adults Without Diabetes.
• Dose-Escalation Regimens for Incretin Mimetics in Type 2 Diabetes are Associated with Tolerance for Nausea and Vomiting.
• Estimating the Effect of Pravastatin Versus Usual Care Under Full Adherence in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial - Lipid Lowering Trial (ALLHAT-LLT).

Food & Diet

• Opinion: Here’s to Brunch, and Lunch!
• Scientists Discover a Way to Make French Fries Healthier Without Losing the Crunch.
• Ultra-Processed Food Intake and Cognitive Decline in Older Adults.
• Ingestive Classics: Gordon C. Kennedy and the Lipostatic Control of Eating.
• Review: Nutrition and Culinary Education in Food Is Medicine Interventions.

Caloric and Dietary Restriction

• Neutrophil-Mediated Anti-Tumoral Effects of Caloric Restriction.
• Meta-Analysis: Efficacy of Different Types of Intermittent Fasting in Improving Glycemic Control in Adults with Overweight or Obesity: A Systematic Review and Network Meta-Analysis.

Exercise & Physical Activity

• Meta-Analysis: Association between Physical Activity Levels and Mortality and Cardiovascular Disease in Chronic Kidney Disease.
• Physical Activity, Nutritional Status, and Health-Related Quality of Life in Newly Diagnosed Cancer Patients: Evidence from the NUTRISCREEN Project.

Economics & Sociology

• Obesity and the Labour Market: Employment, Sick Leave, and Policy Responses.
• Experimental Evidence from the USA Shows That Recurring Unconditional Cash Transfers Improve the Diets of Low-Income Individuals.

Epidemiology

• Circulating Asprosin Levels and Body Weight Changes in Postmenopausal Women.
• Overweight or Obesity and Their Association with Cardiometabolic Risk Factors Among Oilfield Workers in Chinese Population.
• Prevalence and Associated Risk Factors with Overweight, Obesity and Abdominal Obesity Among Women of Childbearing Age Residing in Nouakchott, Mauritania.
• Review: Sarcopenic Obesity in Older Adults.

Psychology & Neuroscience

• Why Deep Brain Stimulation for Obesity Is Ethically Impermissible.
• From a Baby’s Point of View: How Infants’ Face Diets Shape Their Face Perception.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Prebiotics Partially Protect Offspring from Maternal Antibiotic-Induced Obesity Risk by Altering Maternal Milk Microbiota and Gut Colonization in Sprague-Dawley Rats.
• Thesis: Early Life Persistent Organic Pollutant Exposure, BMI, and Thyroid Hormone Levels in a Slovak Cohort.

Stigma

• "Embracing my queerness has actually been really healing for the way that I live in my body": An exploration of queer women's body image and physical activity.
• RCT: A Lived Experience and Education-Based Weight Bias Intervention for Australian Healthcare Students.
• Exploring the Relationships Among Weight Stigma, Weight Bias Internalisation, Feeling Fat, and Self-Esteem Across Preconception, Pregnancy, and Postpartum.

Policy Related

• Assessment of the Presence, Content, and Gaps in Municipal Food Service Guidelines: An Analysis of Policies in the 20 Most Populous U.S. Cities, 2017-2023.
• Correspondence: Ultra-Processed Foods in Research and Policy - Authors' Reply.
• From Endorsement of the WHO Acceleration Plan to Stop Obesity to National Implementation: Country Progress on Health System Preparedness to Scale Up a Comprehensive Obesity Chronic Care Programme.
• Narrative Review: School Meals as a Strategy to Prevent Childhood Obesity and Advance Food Equity.

Intergenerational Effects

• Associations between Maternal Prepregnancy BMI and Maternal and Cord Blood Metabolome.
• Epigenetically Regulated Pancreatic GABA-Somatostatin Signaling Underlies Gestational Diabetes-Induced Glucose Intolerance in Offspring.
• Defining the External Exposome of Newborns from La Palma Island, Spain: Characteristics of Realistic Mixtures and Its Role on Precision Public Health.

Ecology, Evolution, & Energetics

• Begging Efficiency Rather Than Food Received Causes Brood Size Effect on Growth in Zebra Finches.
• Evolutionary Conservation of Lipid-Associated Epigenetic Signatures and Their Distinct Roles in Tissue Identity and Mammalian Aging.

Methods

• Patient Education in Bariatric Surgery: Can Artificial Intelligence-Based Chatbots Bridge the Knowledge Gap?
• National Data Meets AI: Machine Learning for Predicting Overweight/Obesity Among Ever-Married Bangladeshi Women.

Commentary

• Podcast: The New Food Pyramid: Experts React to the Dietary Guidelines.
• Podcast: Rethinking Carbs for Performance with Dr. Andrew Koutnik.
• Crawfish Boils: Healthy or Unhealthy?
• Press Release: Fractyl Health Completes Randomization in REMAIN-1 Pivotal Cohort of Revita for Post-GLP-1 Weight Maintenance.
• Podcast: The Most Effective Weight Training, Cardio & Nutrition for Women | Dr. Lauren Colenso-Semple.
• Persistent Global Confusion About Obesity.
• The Challenge of Coping with the Coexistence of Stunting and Overweight in Young Children.
• Do Obesity Drugs Treat Addiction? Huge Study Hints at Their Promise.

General

• Podcast: Can Astronauts Teach Us How to Age Better? With Longevity Physician Filippo Ongaro.
• What’s Wrong with NIH Grants?
• The Relationship between Psychological Stress and SARS-CoV-2 Nucleocapsid-Antibody Response Following Natural Infection: Longitudinal Findings from the Aegis Study.
• Implementation of Early Peanut Introduction Among Providers in a Southern US State.
• AAMC Member Medical Schools Recognized for Advancing Nutrition Training in Medical Education.
• Chemical Strategies for Mineral Bioavailability.

Announcements

• Director of Body Composition Sought in Division of Nutrition, US Department of Agriculture (USDA) Agricultural Research Service (ARS) Children’s Nutrition Research Center (CNRC), in the Department of Pediatrics at Baylor College of Medicine and Texas Children's Hospital.
• Pediatric Obesity Symposium - March 28th.
• Gut Feeling: Toward Development of an AI Tool for Precision Dietary Carbohydrate Recommendations - Virtual Event.