Featured

• Clinical Predictors of Muscle Function in Adults with Obesity.
• Preprint: Ambient Temperature and Adult Obesity: Evidence from U.S. County-Level Panel Data.
• D-Allulose Reduces Weight More Persistently Than Oral Semaglutide While Both Equally Elevate Grip Strength in Diet-Induced Obese Mice.
• Preprint: Gut-Derived GLP-1 Released by Rare Sugar D-Allulose Cooperates with Insulin to Activate Left-Sided Vagal Afferents and Enhance Insulin Sensitivity.
• Adverse Effect of Obesity and Dysglycemia on Bone Microarchitecture and Strength in Youth: Sex-Related Differences.

Headline vs Study

• Headline: Study Finds Bigger Breakfasts and Lighter Dinners May Aid Weight Loss in Obese Adults.
• Study: RCT Comparing High Fiber Versus High Protein Weight Loss Diets. Breakfast Size Not Tested as a Randomized Condition.

Contrary or Null Findings

• No Evidence for Squaring the Survival Curve: Lifespan-Extending Treatments Increase Variation in Age-At-Death.
• Menstrual Cycle Phase Does Not Affect Carbohydrate Supplementation Ergogenic Effect After Heavy Intensity Cycling.
• Heat Acclimation During the Third Week of a Live-High-Train-High Training Camp Does Not Impair the Hematological and Perceptual Responses to Altitude.
• RCT: Regular Cold-Water Immersion Following HIIT Does Not Affect Intramuscular Adaptation Markers, Inflammatory Profile or Endurance Performance.
• Vitamin B12 Deficiency Does Not Induce Homocysteine Increase in Transfusion-Dependent β-Thalassemia Major Patients Receiving Folic Acid Supplementation.
• Statin Use Does Not Impair Muscle Health in Older Adults: Findings from the SCOPE Study.
• "No single nutrition support intervention emerged as superior for all outcomes of interest, although current best practices were supported. Certainty of evidence was very low for primary outcomes, and heterogeneity limited conclusions for secondary outcomes."
• RCT: "Differences between WL+VEST and WL were insignificant..."

Basic

• Liver-Derived Indian Hedgehog (Ihh) Couples Fast-Feed Transition to Thermogenic and Metabolic Homeostasis.
• Impact of Sodium Butyrate Supplementation on Insulin Resistance and Adipose Tissue Modulation in Murine Models of Polycystic Ovary Syndrome.
• Central Irisin Administration Attenuates Hypothalamic TLR4/MyD88-Mediated Neuroinflammatory Signaling in Diet-Induced Obese Mice.
• TRPC6 Governs Brown Adipose Thermogenesis Via a BMPR2-P38 MAPK Signaling Axis.
• MEDAG Functions as an A-Kinase-Anchoring Protein in Adipocytes.
• Sucralose and PMMA Microplastics Synergistically Induce Obesity with Altered Locomotion and Metabolism in Caenorhabditis elegans.
• Dissertation: The Role of the Neuropeptide Y System in the Pancreas in the Development of Obesity and Diabetes.

Scientific Rigor & Scholarly Dialogue

• Journal Retracts GLP-1 Study After Researcher Questions Central Finding.
• Implausible Apple Cider Vinegar Weight Loss Study Retracted.
• I Tried to Design a Clinical Trial for a Supplement. 5 Things Got in the Way.
• Webinar: Recording Available For: David B. Allison (Baylor College of Medicine, USA) (Virtual), Truth, Trust, Trustworthiness, and Transparency: Foundations for Rigorous Science and Communication.

Clinical

• Trends in Use of Obesity Medications and Metabolic and Bariatric Surgery Among All of Us Participants from 2003 to 2023.
• Estimating the Clinical, Quality-Of-Life and Economic Impact of Optimized Management of Type 2 Diabetes Patients in Spain.
• Clinical Characteristics, Treatment Patterns, and Healthcare Utilization Among Children, Adolescents, and Young Adults with Obesity in the United States.
• Experience and Acceptability of a Reduced-Energy Whole-Diet Intervention in Women with Gestational Diabetes: A Qualitative Study of the Dietary Intervention in Gestational Diabetes Trial.
• The Effect of Whole-Body Cryostimulation Treatments on the Profile of Selected Adipokines and Sirtuins in Middle-Aged Individuals with Varying Degrees of Body Fatness.
• BMI Impact on Health Care Utilization Among People with Diabetes in Jeddah, Saudi Arabia.

Children and Adolescents

• Prevalence of Overweight and Obesity and Associated Lifestyle Factors Among Apparently Healthy School-Going Children Aged 5-15 Years in Urban Lucknow.
• Pediatric Obesity Treatment: From Paradigm Shift to Implementation Challenges.
• Regional, Socioeconomic, and Health Determinants of Physical Fitness in School Children: Insights from a National Olympic Fitness Project.
• Decoding Adolescents’ and Parents’ Perspectives of Overeating.
• Systematic Review: Built Environment and Childhood Obesity. (pdf)
• Proximal and Distal Factors Associated with Obesity in Childhood: An Exploratory Structural Equation Model.
• Novel Epigenetic Marks of Insulin Resistance Trajectories in a Longitudinal Study of Childhood Obesity.
• Integrative Network Toxicology and Molecular Docking Preliminarily Explore the Potential Role of Polystyrene Microplastics in Childhood Obesity.
• Evaluating School-Based Obesity Prevention Interventions in 6-12-Year-Old Children: A Scoping Review of All Reported Outcomes and Expert Consultation.

Surgery

• Preprint: Phubbing Behaviors and Psychological Distress in Patients with Obesity Scheduled for Bariatric Surgery.
• Roux-En-Y Gastric Bypass, Adjustable Gastric Banding or Sleeve Gastrectomy for Severe Obesity.

Drugs

• Heterogeneity of Treatment Effects of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss in Adults.
• RCT: Efficacy and Safety of Bofanglutide, a GLP-1 Receptor Agonist, in Chinese Adults with Overweight or Obesity.
• Real-World 6-Month Persistence, Adherence, and Effectiveness of GLP-1 Medications for Overweight and Obesity in a Medicaid Population.
• Narrative Review: GLP-1 Receptor Agonists for Obesity in Older Women: Maximizing Weight Loss While Preserving Lean Mass.

Food & Diet

• Narrative Review: Relationship between Hypovitaminosis C, Obesity, and Features of Metabolic Syndrome.
• Systematic Review: Effectiveness of Whey Protein Supplementation in Weight Loss Interventions for Patients with Obesity.
• RCT: Effects of Cafeteria Diet and Caloric Restriction on Pituitary Hormones and Metabolic Phenotype in Male Wistar Rats. (pdf)
• Consuming an Unprocessed Diet Reduces Energy Intake: A Post-Hoc Analysis of a RCT Reveals a Role for Human Nutritional Intelligence.

Caloric and Dietary Restriction

• Intermittent Fasting for Adults with Overweight or Obesity.
• Prenatal Caloric Restriction Reprograms Endothelial Transcriptional States and Blood-Brain Barrier Integrity: Implications for Neurodevelopmental Disorders.

Exercise & Physical Activity

• The Location of Physical Activity Determines Its Efficacy on Vitamin D Status.
• Relationship between BMI, Insulin Resistance, and Metabolic Syndrome in Children: Effect of Vigorous Physical Activity.
• Preprint: Leisure-Time Physical Activity on Lifelong Trajectories of BMI and Obesity Risk Throughout Life: Multivariable Regression and Mendelian Randomization Analyses Using Real-World Data from the CORDELIA-Catalunya Study.

Economics & Sociology

• Associations between Neighborhood Socioeconomic Status and Cardiometabolic Health Among Asian American Residents of New York City.
• Ozempic and Wegovy Meet Congress: Political Economy Without Critique and Sociology Without Society.
• Maternal Higher Education and Children’s Weight: Evidence from the College Enrolment Expansion in China.
• The Secular Trend of the BMI of the U.S.-Born Population and the Rise of an Obesogenic Environment, 1882-2021.
• The Economics of a Sin Tax on Sugar-Sweetened Beverages.

Epidemiology

• Associations of Obesity, Systemic Inflammation, and Hyperinsulinemia with the Incidence of Non-Communicable Chronic Disease and Mortality.
• A Cross-Sectional Study Assessing Association of Renal Cell Carcinoma Pathological Grade and Stage with BMI and Obesity Related Factors.
• Body Fat Percentage Is Independently Associated with Lower Pulmonary Function in Korean Never-Smokers.
• Traditional, Central Obesity, and Metabolic Indices: Which Metrics Better Reflect Osteoarthritis Risk?
• Review: The Association of Obesity with Cardiovascular Disease Risk and Risk-Enhancing Factors.
• Prevalence and Determinants of Underweight, Overweight, and Obesity Among Reproductive-Aged Bangladeshi Women.
• Prevalence of Childhood Overweight and Obesity in Slovakia from 2018 to 2022.
• BMI Threshold for Obesity Should Be Personalized Based on Polygenic Score: Analysis of European and East Asian Biobanks.
• Sex-Specific Individual and Joint Associations of Multiple Environmental Exposures with Diabetes and Obesity in the Population-Based German National Cohort.
• Effects of Body Composition on Age- and Sex-Related Differences in Resting Metabolic Rate from a Healthy Aging Cohort.

Psychology & Neuroscience

• A Dorsal Hippocampus-Prodynorphinergic Dorsolateral Septum-To-Lateral Hypothalamus Circuit Mediates Contextual Gating of Feeding.
• Elevated BMI in Youth Is Associated with Neural Disinhibition and Internetwork Functional Dysconnectivity: A Magnetoencephalography Study.
• The Impact of Exercise on Dietary Fat Taste Perception: A Report on Its Role in Obesity Prevention.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Access to Obesity Medicine Specialists and Endocrinologists for Populations with Obesity in US Counties, Is There a Rural-Urban Divide?
• Racial/Ethnic Disparities in Stages of Cardiovascular-Kidney-Metabolic Syndrome Among Reproductive-Aged Women in the United States: NHANES 2011-2020.

Stigma

• Analysis of the Relationship between Physical Education Majors' Perceptions of Their Body Shape and Fatphobia.
• Experiences of Weight Stigma Before and During the COVID-19 Pandemic: A Cross-Sectional Analysis.
• Exploring Strategies for Addressing Weight Stigma: An Analysis of Health Communication Dynamics and Evolutionary Themes.

Policy Related

• Scientific Advisory Committee on Nutrition’s Report on Feeding Young Children Aged 1 to 5 Years.
• Quantifying Objective In-School Physical Activity During Recess and Physical Education in 6-12-Year-Old Children.
• The Future of Food Processing - A Food Science and Technology Perspective. Proceedings of a Roundtable Event.
• Scoping Review: Facilitators and Barriers to the Formulation of Public Policies on Food and Nutrition.
• Commentary: A Critical Evaluation of the 2025 - 2030 Dietary Guidelines for Americans.

Intergenerational Effects

• Epigenetic Analyses Suggest Different Pathways During Pregnancy for Development of Type 1 Diabetes in Children with High Versus Low-Neutral Human Leukocyte Antigen-Risk.
• Obesity-Associated Gestational Diabetes Promotes Cellular Heterogeneity and Dysfunction in Neonatal Offspring-Islets.
• Timing of Food Insecurity and Associations with Parent Feeding Behaviors and Toddler Weight Status.

Methods

• Scoping Review: Language Models in Nutrition and Dietetics.
• Validity of the Diet Quality Questionnaire Compared with Observed Intake for Estimating Population-Level Diet Quality in Rwandan Adults.
• Predictive Equations Commonly Used in the Clinic Underestimate Resting Energy Expenditure Compared with Whole-Room Indirect Calorimetry in Colorectal Cancer Survivors.

Commentary

• Intermittent Fasting: It’s Just a Diet, No Magic.
• Scientific American Podcast: How Seed Oils Became Controversial - And What the Science Really Says.
• Orforglipron vs Oral Semaglutide 1.0 in Lancet.
• Are We Prescribing GLP-1s Wrong?
• Choline Adequacy and Health Outcomes in Vegetarian and Vegan Diets.
• The Science of Safety: Adverse Effects of GLP-1 Receptor Agonists as Glucose-Lowering and Obesity Medications.
• Taurine May Improve Multiple Cardiometabolic Risk Factors.
• The Language of GLP-1 Medication in UK Media Discourse: A Diachronic Perspective.
• What Is the Likely Impact of the Proposed Food and Drug Administration Front-Of-Package Criteria on the Labeling of Foods?
• Details Emerge on Obesity Medicines in Medicare.
• The Fading Fiction of Inflated GLP-1 List Prices.

General

• The Vicious Spiral of AI Slop.
• Why Do Cells Need to Die?
• OMICmAge Quantifies Biological Age by Integrating Multi-Omics with Electronic Medical Records.
• The Spark of Life: Bioelectronics That Orchestrate Cell Functions for Disease Control.
• Should Lipid Screening Start Earlier in Children with Type 1 Diabetes?
• Podcast: This New Study Will Change How You Think About Fatigue.
• Podcast: Stress Ages Us on a Cellular Level.
• Frozen Fruit and Vegetable Perceptions and Usage Among a Multistate Sample of Supplemental Nutrition Assistance Program Education and Expanded Food and Nutrition Education Program Participants.
• Systematic Review: Fiber Intake and Laxation in People with Normal Bowel Function.

Announcements

• Baylor College of Medicine Seeks Postdoctoral Associate - Nucleic Acid Delivery.
• Director of Body Composition Sought in Division of Nutrition, US Department of Agriculture (USDA) Agricultural Research Service (ARS) Children’s Nutrition Research Center (CNRC), in the Department of Pediatrics at Baylor College of Medicine and Texas Children's Hospital.