Featured

• RCT: Effects of Lean Pork on Microbiota and Microbial-Metabolite Trimethylamine-N-Oxide: Non-Inferiority Feeding Trial Based on the Dietary Guidelines for Americans.
• Reassessing Human Adipose Tissue.
• Adenovirus 36 Infection and Obesity Risk: Current Understanding and Future Therapeutic Strategies.

Headline vs Study

• Headline: Supportive Parenting Reduces Children’s Risk for Obesity, Study Finds.
• Study: Associations Among Family Psychosocial Assets, Child Behavioral Regulation, and Obesity Trajectories. Causal Effects of Supportive Parenting Not Established.

Contrary or Null Findings

• RCT: Overall, Cocoa Flavanols Did Not Improve Visual Working Memory Recall Performance During Maintenance, nor Did It Improve Recall Accuracy After Memory Updating.
• RCT: “...cocoa had no significant effects on serum and fecal metabolites and that its consumption had little impact on the metabolome after a bout of physical exercise."
• RCT: "Clinical Intervention to Reduce Dietary Sugar does not Impact Liver Fat in Latino Youth, Regardless of PNPLA3 Genotype."
• RCT: No Significant Effect of Dietary Glycemic Index on β-Cell Function in Prediabetes.
• RCT: No Statistically Significant Effect of Nutrition and Exercise Intervention from Early Pregnancy to Achieve Recommended Gestational Weight Gain.
• RCT: No Significant Effect of Aerobic Exercise Intensity on Health-Related Quality of Life in Severe Obesity.
• RCT: No Effect of Combined Tele-Exercises and Nutritional Coaching on Anthropometric, Body Composition or Exercise Capacity Outcomes in Women with Overweight and Obesity.
• "There is probably little to no difference in weight reduction and changes in cardiovascular risk factors up to two years' follow-up, when [participants with overweight and obesity] without and with T2DM are randomised to either low-carbohydrate or balanced-carbohydrate weight-reducing diets."

Basic

• Moderate L-Lactate Administration Suppresses Adipose Tissue Macrophage M1 Polarization to Alleviate Obesity-Associated Insulin Resistance.
• Whole Body Ip6k1 Deletion Protects Mice from Age-Induced Weight Gain, Insulin Resistance and Metabolic Dysfunction.
• Latexin Deficiency Attenuates Adipocyte Differentiation and Protects Mice Against Obesity and Metabolic Disorders Induced by High-Fat Diet.
• Matrine Counteracts Obesity in Mice Via Inducing Adipose Thermogenesis by Activating HSF1/PGC-1α Axis.
• Early Time-Restricted Feeding Amends Circadian Clock Function and Improves Metabolic Health in Male and Female Nile Grass Rats.

Scientific Rigor & Scholarly Dialogue

• Nutritional Epidemiology: Abolition vs Defending the Status Quo.
• Article: Nutrition Self-Efficacy Assessment: Designing and Psychometric Evaluation in a Community-Dwelling Elderly Population.
• Letter: Concerns Regarding the Validity of Nutrition Self-Efficacy Questionnaire Among Iranian Elderly Population.
• PubPeer Comment: Statistical Problems in the Vitamin C Trial with PCI Patients by Shafaei-Bajestani Et Al. (2019).
• PubPeer Comment: Statistical Problems in the Vitamin C Trial with CABG Patients by Moludi Et Al. (2020).
• PubPeer Comment On: Vitamin D Supplementation to Prevent Acute Respiratory Infections: A Systematic Review and Meta-Analysis of Aggregate Data from Randomised Controlled Trials.
• Preprint: Vitamin D and Acute Respiratory Infection: Secondary Analysis of a Previous Randomised Controlled Trial and Updated Meta-Analyses.
• 36-Fold Higher Estimate of Deaths Attributable to Red Meat Intake in Global Burden of Diseases, Injuries, and Risk Factors Study 2019: Is This Reliable?

Clinical

• RCT: Family-Based Treatment of Children with Severe Obesity in a Public Healthcare Setting.
• Clinical Use of the Edmonton Obesity Staging System for the Assessment of Weight Management Outcomes in People with Class 3 Obesity.

Children and Adolescents

• Systematic Review: Social Media and Children's and Adolescents’ Diets.
• Review: Understanding Sex Differences in Childhood Undernutrition.

Surgery

• RCT: The Impact of Telephone-Based Cognitive Behavioral Therapy on Mental Health Distress and Disordered Eating Among Bariatric Surgery Patients During COVID-19.
• Review: Effect of Obesity Surgery on Taste.
• Medications Activating Tubular Fatty Acid Oxidation Enhance the Protective Effects of Roux-En-Y Gastric Bypass Surgery in a Rat Model of Early Diabetic Kidney Disease.

Drugs

• Meta-Analysis: Efficacy and Safety of SGLT-2i in Individuals with Overweight/Obesity but not Diabetes.
• Insulin Delivery and Glucose Variability Throughout the Menstrual Cycle on Closed Loop Control for Women with Type 1 Diabetes.
• Development of in Vitro Three-Dimensional Drug Screening System for Obesity-Related Metabolic Syndrome.
• Impact of Obesity on Brexpiprazole Pharmacokinetics: Proposal for Improved Initiation of Treatment.
• Camptothecin Effectively Treats Obesity in Mice Through GDF15 Induction.

Food & Diet

• RCT: Consumption of Caffeinated and Decaffeinated Coffee Enriched with Cocoa and Fructo-Oligosaccharides Among Persons without Diabetes.
• Meta-Analysis: Effects of Dietary Patterns on Biomarkers of Inflammation and Immune Responses.
• Review: Effects of Alpha Lipoic Acid on Metabolic Syndrome.
• Review: Fruit Juice and Childhood Obesity.
• "Greater consumption of ultra-processed foods was associated with higher all-cause mortality in this health-conscious Adventist population with many vegetarians"
• Nutrient Pattern Analysis of Mineral Based, Simple Sugar Based, and Fat Based Diets and Risk of Metabolic Syndrome.
• Characterisation, Procedures and Heritability of Acute Dietary Intake.

Caloric and Dietary Restriction

• RCT: Time-Restricted Eating in Healthy Volunteers Without Obesity.
• Review: Is Calorie Restriction Beneficial for Normal-Weight Individuals?
• Satiety Associated with Calorie Restriction and Time-Restricted Feeding: Peripheral Hormones.

Exercise & Physical Activity

• Meta-Analysis: The Effect of Exercise Interventions on Irisin Level.
• Case Study: Bicycle Touring 480 Km in Seven Days: Effects on Body Composition and Physical Fitness.
• Trends in Gross Body Coordination and Cardiorespiratory Fitness from 35,000 2nd Graders.
• Exercise in People with Cancer: A Spotlight on Energy Regulation and Cachexia.
• Acute Aerobic Exercise Reveals Fatty Acid Esters of Hydroxy Fatty Acids Distinguish the Metabolomes of Overweight and Normal Weight Runners.

Economics & Sociology

• Marketing of Sugar-Sweetened Children's Drinks and Parents' Misperceptions About Benefits for Young Children.
• Potentially Modifiable Mediators for Socioeconomic Disparities in Childhood Obesity in the United States.

Epidemiology

• Age at Childbirth and Change in BMI Across the Life-Course.
• Association of Weight at Different Ages and All-Cause Mortality Among Older Adults in the US.

Psychology & Neuroscience

• Relations of Metabolic Health and Obesity to Brain Aging in Young to Middle-Aged Adults.
• Novel Clinical Algorithm for Hypothalamic Obesity in Youth with Brain Tumours and Factors Associated with Excess Weight Gain.
• Regional Gray Matter Abnormalities in Pre-Adolescent Binge Eating Disorder.

Equity and Disparities

• Responding to Health Disparities in Behavioral Weight Loss Interventions and COVID-19 in Black Adults: Recommendations for Health Equity.
• Metabolic Syndrome in Childhood Cancer Survivors: Delta BMI a Risk Factor in Lower-Middle-Income Countries.
• Food Insecurity and Ultra-Processed Food Consumption: The Modifying Role of Participation in the Supplemental Nutrition Assistance Program.

Stigma

• The Impact of Curvy Fitspiration and Fitspiration on Body Dissatisfaction, Negative Mood, and Weight Bias in Women.
• Weight-Normative Versus Weight-Inclusive Narratives in Weight-Related Public Health Campaigns: Effects on Anti-Fat Attitudes, Stigma, Motivation, and Self-Efficacy.

Policy Related

• Scoping Review: Barriers, Frameworks, and Mitigating Strategies Influencing the Dissemination and Implementation of Health Promotion Interventions in Indigenous Communities.
• Review: The Benefit of Telemedicine in Obesity Care.
• Review: How Can We Act to Mitigate the Global Syndemic of Obesity, Undernutrition, and Climate Change?

Intergenerational Effects

• Review: Gestational Obesity: An Unconventional Endocrine Disruptor for the Fetus.
• Effect of Nutritional Variance of Energy and Crude Protein on Sex Ratio and Development of W-36 Parent Offspring.
• Maternal Diet and Obesity Shape Offspring Central and Peripheral Inflammatory Outcomes in Juvenile Non-Human Primates.
• Maternal Postnatal Early Overfeeding Induces Sex-Related Cardiac Dysfunction and Alters Sexually Hormones Levels in Young Offspring.
• Smoking During Pregnancy Is Associated with Child Overweight Independent of Maternal Pre-Pregnancy BMI and Genetic Predisposition to Adiposity.

Ecology, Evolution, & Energetics

• PodCast: The Amphibian Omnivore's Dilemma: Plasticity-Led Evolution in Spadefoot Tadpoles.
• The Possible Role of Body Temperature in Modulating Brain and Body Sizes in Hominin Evolution.

Methods

• Meta-Epidemiological Study: Evaluating Concordance of Bodies of Evidence from RCTs, Dietary Intake, and Biomarkers of Intake in Cohort Studies.
• Consensus Statement: Definition and Diagnostic Criteria for Sarcopenic Obesity.

Mathematical and Quantitative

• Body Fat Prediction Through Feature Extraction Based on Anthropometric and Laboratory Measurements.
• Exploring an Algorithm to Harmonize International Obesity Task Force and World Health Organization Child Overweight and Obesity Prevalence Rates.

Commentary

• Diet Culture Comes for Pets.
• Another Effective and Ineffective Anti-Obesity Policy.
• Bariatric Surgery to Reduce Breast Cancer Risk?
• The Longevity Diet According to Science: How to Eat to Live Longer and Better.
• Weight-Loss Shot May Reduce Obesity, Overweight.
• Perspective: Opportunities and Challenges of Technology Tools in Dietary and Activity Assessment: Bridging Stakeholder Viewpoints.
• The Potential Impact of Climate Change on the Micronutrient-Rich Food Supply.
• Is Calorie Restriction the Key to Longevity?

General

• RCT: Criminalizing Poverty: The Consequences of Court Fees.
• Preprint: The Drosophila melanogaster Enzyme Glycerol-3-Phosphate Dehydrogenase 1 Is Required for 7 Oogenesis, Embryonic Development, and Amino Acid Homeostasis.
• A Simple Eye Test Can Identify the Risk of Alzheimer’s.
• Evaluating the Cost-Effectiveness of a Pre-Exposure Prophylaxis Program for HIV Prevention for Men Who Have Sex with Men in Japan.
• Population Analysis of Retrotransposons in Giraffe Genomes Supports RTE Decline and Widespread LINE1 Activity in Giraffidae.
• Recognition of Observer Effect Is Required for Rigor and Reproducibility of Preclinical Animal Studies.
• A Call for More Rigor in Science and Health Communication.
• Testing Use of the First Multi-Partner Cognitive Enrichment Devices by a Group of Male Bottlenose Dolphins.

Video & Audio

• PodCast: Attia & Allison on the Science of Obesity & How to Improve Nutritional Epidemiology.

Announcements

• “Lloyd J. Kolbe, PhD, Emeritus Professor of Applied Health Science at the Indiana University School of Public Health Bloomington Will Receive SOPHE's Highest Honor, the Distinguished Fellow Award.
• IU Bloomington a Top Producer for Fulbright U.S. Student Program for 2021-22.
• Department Chair and Tenured/Tenure Track Professor of Kinesiology Sought at IU.
• The Indiana University School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency And/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• IU Bloomington School of Public Health Is Recruiting Tenure-Track Faculty in Every Department! A Sampling of Opportunities Is Here, but Even Departments Not Yet Listed are Recruiting.
• Nutrition Science Non-Tenure-Track Search: Clinical Full-Associate-Assistant Professor; Senior Lecturer or Lecturer.
• Nutrition Science Tenure/Tenure-Track Search: Full Professor/Associate-Assistant Professor.