02/20/26
Featured
- Plasma Biomarkers of Senescence in Cholestatic Liver Disease: A Signature of Risk Stratification and Progression.
- Advancing Protein Quality Knowledge and Access with a Centralized and Interactive Database.
- Dietary Fats, Blood Lipids & Atherosclerotic Cardiovascular Disease: Time for Food-Based Approach?
- Preprint: "The limited use of rigorous causal inference approaches remains a key barrier to producing actionable evidence in microbiome research...Only 15% of studies used designs or analytical strategies capable of approximating causal effects..." (pdf)
Headline vs Study
- Headline: Icelandic Study Finds Following Nutritional Guidance Reduces Children’s Obesity Risk.
- Study: Infant Diet Score Is Inconsistently Associated with (not Necessarily Causally Related To) BMI in Some Parts of Childhood.
Contrary or Null Findings
- RCT: "The labeling intervention did not reduce kcal purchased" in Trial of "Changing portion size labels of main courses to encourage selection of smaller portions when dining out".
- RCT: "Neither MetS z-scores nor MetS prevalence had statistically significant improvements" in "Effect of the healthy school recognized campus initiative on metabolic syndrome among adolescents in Texas…".
- RCT: "In line with earlier observations in relatively healthy populations, long-term almond consumption (50 g/day) did not enhance cognitive performance in overweight/obese individuals with prediabetes. Moreover, brain vascular function was unaffected."
- RCT: "Providing free FVs without focused interventions to improve diet quality and reduce waste fails to increase FV intake and increases FV waste."
- RCT: "No additional effects on fecal short-chain fatty acids (SCFAs) concentrations or human health markers were identified" in "Impact of Yogurt and Rolled Oats Consumption on the Gut Microbiome: A Randomized Crossover Study displaying Individual Responses and General Resilience."
- RCT: "21 days of n-3 fatty acid supplementation modified PUFA content and influenced inflammation status, but did not affect maximal anaerobic performance."
- RCT: "No significant between-group differences were detected for anthropometric or metabolic outcomes after adjustment" in "Multicomponent Nutritional Approach (NutrirCom) and Its Effects on Anthropometric, Metabolic, and Psychoemotional Outcomes in Women with Obesity".
- Meta-Analysis of RCTs: "Vitamin D supplementation was safe and well-tolerated, but no meaningful clinical benefit was identified for hepatic or metabolic parameters of interest in MASLD."
- RCT: "Daily consumption of 4 oz of beef or plant-based meat for 8 wk does not affect cardiometabolic risk factors in [women of reproductive age] with low iron stores."
Basic
- Siah2 Is a Lipid-Meditated Metabolic Sensor in Adipose Tissue Macrophage.
- Growth Hormone Enhances Mitochondria Biogenesis and Endows Mitochondrial Thermogenesis in Murine Adipocytes.
- Ufmylation-Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN-Mediated Adipocyte Lipogenesis.
- C/EBPα Is Essential for Gonadal but Not Inguinal White Adipose Tissue Formation in Mice.
Scientific Rigor & Scholarly Dialogue
- Podcast: Dr. Jordan Gebhardt: Precise Experimental Design | Ep. 84 [The Swine Nutrition Blackbelt Podcast].
- Coffee Is Great but It Does Not Prevent Dementia.
Clinical
- Harnessing Metabolic Insights: A Framework for Dietary Patterns in Chronic Disease Prevention and Management.
- RCT: Choline and Betaine Concentrations in Plasma Discriminate Levels of Dietary Choline Intake in Healthy Adults.
- A Factorial Model of the Minimum Metabolic Demand for Protein and Indispensable Amino Acids in Young Adult Males: Implications for Current Recommendations.
Children and Adolescents
- Children’s Healthy Weight State Capacity Building Program: Incorporating Nutrition Into States’ Maternal and Child Health Programming.
- Clinical and Biological Phenotypes of Patients Carrying a Heterozygous Variant in Genes of Leptin-Melanocortin Signaling Pathway.
- A Growing Burden: Obesity’s Impact on Cardiometabolic Disease Risk in Children and Adolescents.
Surgery
- Obesity Does Not Influence the Outcomes of Minimally Invasive Mitral Valve Repair for Mitral Regurgitation.
- Nutritional Management of an Adolescent Undergoing Bariatric Surgery.
- Retrospective Study: Active GLP-1 RA Use Is Associated with Lower Rates of Surgical Complications Across BMI Cohorts with Diabetes.
Drugs
- JAAD CME Part 2: Clinical Evidence and Safety Considerations for GLP-1 Receptor Agonists in Dermatology.
- Meta-analysis: Semaglutide and the Risk of Non-Arteritic Ischemic Optic Neuropathy.
Food & Diet
- Editorial: Reconsidering the Role of Full-Fat Dairy: Beyond Nutrient Reductionism.
- Review: Molecular Mechanisms of Lignans in Lowering Blood Pressure and Anti-Obesity Effects.
Caloric and Dietary Restriction
- Impact of Caloric Restriction and Resistance Training on Weight Management, Insulin Sensitivity, and Adipose Tissue Protein Dynamics [in rats].
- Oxytocin, Weight Loss and Ketosis in Response to a Very-Low-Calorie Ketogenic Diet: An Exploratory Study.
Exercise & Physical Activity
- Seven-Year Changes of BMI and Grip Strength in Older Adults: Incidence of the Obese-Weak Phenotype and the Protective Role of Physical Activity.
- Association between Eating Speed, Body Composition, and Physical Activity: A Cross-Sectional Study in Gujarat, India.
- High-Speed Resistance Training Vs. Low-Speed Resistance Training on Body Composition and Physical Function in Adults with Sarcopenic Obesity.
Economics & Sociology
- Estimating the Causal Effect of Cardiometabolic Conditions on Socioeconomic and Healthcare Outcomes: A Scoping Review of Mendelian Randomization Studies.
- Household Food Insecurity Is Associated with Higher Adiposity over Time Among Adolescents in Louisiana.
- How Does the Built Environment Affect Obesity? A Review from the Perspective of Urban Planning.
- Does Urban Environment at Birth and Adolescence Affect Cardiometabolic Morbidity in Adolescents?
Epidemiology
- Review: Obesity in 2026: Analyzing the Rapid Rise and Pathways to Prevention.
- Modeling of Ultraprocessed Foods Taxation on Overweight Prevalence and Noncommunicable Diseases in Brazil.
Psychology & Neuroscience
- Commentary: ...on “Emotional and External Eating Behaviors Associated with Fat-Free Mass Loss Following Sleeve Gastrectomy”.
- Review: Mental- and Physical Health, and General Well-Being in Patients with Polyposis Syndromes.
Differential Population Circumstances, Exposures, Outcomes, and Effects
- Genetic Insights Into Socioeconomic Inequalities and Adiposity-Related Interventions for Reducing Accelerated Biological Aging.
- Temporal Trends and Disparities in Cardiovascular Mortality Among Adults with Obesity in the United States from 1999 to 2023.
Stigma
- Weight Stigma Among Diverse Ethnic Groups with Obesity in the U.S.: The USA-OBESTIGMA Study.
- RCT: Feasibility Study Assessing Acute Physiological Responses to Weight Stigma in Women Living with Obesity.
- Addressing Weight Stigma in Medical Education: Insights and Strategies from a Nutrition Curriculum Review.
Policy Related
- Children’s Perspectives of Their Everyday Food Practices: Insights to Inform Policy and Interventions.
- Medicaid and Health Resilience: Evidence from TennCare Disenrollment.
- BMI Was Maintained Among Women with Low Incomes in Indiana Who Participated in Food Assistance and/or Federal Nutrition Education over 1 Year.
- Anticipating Unintended Consequences of Public Health Nutrition Policy: Implications for Disordered Eating and Weight Stigma.
- Perspectives on Universal Free School Meals Among Rural Middle and High School Students: A Mixed-Methods Study.
Intergenerational Effects
- Growing Inequities in Median Age of Death and Obesity Prevalence between Australian Major Cities and Remote Areas.
- Placental mRNA and miRNA Dynamics Associated with Lipid Metabolism Pathways in Pregnancies Affected by Obesity.
- Fetal Growth Outcomes in Early Gestational Diabetes Mellitus Managed Immediately After Diagnosis.
Ecology, Evolution, & Energetics
- The Evidence for Constrained Total Energy Expenditure in Humans and Other Animals.
- Urban Green Space and Its Impact on the Health of Urban Residents.
- Chapter: Advances in Marine Medical Nutrition: Achieving an Ecological Balance.
- Protective Effects of Neutral Lipids from Phaeodactylum tricornutum on Palmitate-Induced Lipid Accumulation in HepG2 Cells: An in Vitro Model of Non-Alcoholic Fatty Liver Disease.
Methods
- Multi-Omics Analysis of Morbid Obesity Using a Patented Unsupervised Machine Learning Platform: Genomic, Biochemical, and Glycan Insights.
- OBE-DB: A Computational Tool and Web Server for the Prediction of Obesity Drugs.
Commentary
- Does Exercise Actually Burn Calories?
- Podcast: Should Ultraprocessed Foods Be Off the Menu?
- Podcast: Debated: Seed Oils, Beef Tallow, Raw Milk, Eggs, and Soy | Max Lugavere.
- Podcast: Seed oils vs. beef tallow, with Unbiased Science.
- Researchers are Applying Insights Into the Genetic Variations and Physiology of Obesity to Apply Tailored Interventions to Patients to Improve Treatment Outcomes.
- The Misguided Effort to Equate Food with Tobacco.
- Super Bowl Food Ads Aren’t Causing the Obesity Problem.
- Toward Reproducible Metabolism Research: Consensus Emerges on Preclinical Indirect Calorimetry.
- Popular Weight-Loss Plan Is More Hype Than Help, New Study Finds: ‘Doesn’t Justify the Enthusiasm.’
General
- miRNAs Shape Mouse Age-Independent Tissue Adaptation to Spaceflight Via ECM and Developmental Pathways. (pdf)
- Preprint: A Searchable Metadata Network Graph for Microbiome Metabolomics.
- APOE-Stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer’s Disease.
- Preprint: Balance between DNA Repair, LINE1 Suppression and Lifespan in Mice with SIRT6 Serine 10 Phosphorylation Site Mutations.
- Study Finds Termites Built Mega-Colonies by Losing Genes, Not Gaining Them.
- Review: Protein Supplements and Protein-Containing Product Use in Ice Cream.
- Semaglutide Ameliorates Osteoarthritis Progression Through a Weight Loss-Independent Metabolic Restoration Mechanism.
- Follow‑Up: Drs. Ballantyne and Abushamat Discuss Follow‑up Care for a Young Patient with FCS on Quarterly Triglyceride‑lowering Injections.
- Episode #386: Longevity Myths- Biological Clocks, GLP-1 Muscle Loss, and What Actually Predicts Lifespan.