Featured

• Special Announcement: A Good Man and a Good Scientist Passes: John O. Holloszy: An Enduring Legacy in Exercise Physiology, Aging and Muscle Research.
• Associations Between SLC16A11 Variants and Diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
• A Winter Energetics Model for Bobcats in a Deep Snow Environment.
• Communicating Inequalities to Enhance Support for Obesity-Prevention Policies: The Role of Social Comparisons, Age Frames, and Emotion.

Headline vs Study

• Headline: New Science Shows Managing Blood Sugar Isn’t About Counting Calories or Carbs.
• Study: Assessment of a Personalized Approach to Predicting Postprandial Glycemic Responses to Food Among Individuals Without Diabetes. Management of Blood Sugar Not Evaluated.

Contrary or Null Findings

• No Evidence for Overweight in Long-term Childhood Cancer Survivors After Glucocorticoid Treatment.
• "Results of this meta-analysis study failed to show any beneficial effect of coenzyme Q10 supplementation on body weight and BMI of patients in clinical trial studies."
• RCT: "The hypothesis was not supported, our findings indicated that after 8 weeks, the Nordic walking training did not result in greater improvements than free walking training for the primary outcome (self-selected walking speed) and most of the secondary outcomes ..."
• Adiponectin Deficiency Has No Effect in Murine Autoimmune Myocarditis.
• Mitochondrial Uncoupling Has No Effect on Microvascular Complications in Type 2 Diabetes.
• High BMI at Time of Diagnosis Has No Effect on Clinical Outcomes for HER2-positive Breast Cancer.
• High-Protein Diet Has No Effect on Sleep Quality and Quantity in Exercise-Trained Men and Women. (pdf)
• No Effect of Beetroot Juice Supplementation on Exercise Economy and Performance in Recreationally Active Females Despite Increased Torque Production.
• RCT: "In the context of caloric restriction, there seems to be no additional beneficial impact of reduced red meat intake and increased fiber intake on the improvement in cardiometabolic risk parameters."

Basic

• The Nematode Caenorhabditis Elegans as a Model Organism to Study Metabolic Effects of ω-3 Polyunsaturated Fatty Acids in Obesity.
• FAM13A and POM121C are Candidate Genes for Fasting Insulin: Functional Follow-Up Analysis of a Genome-Wide Association Study.
• High-fat Diet Disturbs Lipid Raft/TGF-β Signaling-mediated Maintenance of Hematopoietic Stem Cells in Mouse Bone Marrow.
• Unlike Calorie Restriction, Roux-en-Y Gastric Bypass Surgery Does Not Increase Hypothalamic AgRP and NPY in Mice on a High-fat Diet.
• Opposing Actions of Adrenocorticotropic Hormone and Glucocorticoids on UCP1-Mediated Respiration in Brown Adipocytes.
• Resveratrol-induced Gut Microbiota Reduces Obesity in High-fat Diet-fed Mice.
• Dietary Effects on the Determinants of Food Choice: Impulsive Choice, Discrimination, Incentive Motivation, Preference, and Liking in Male Rats.
• Consumption of Drinking Water N-Nitrosamines Mixture Alters Gut Microbiome and Increases the Obesity Risk in Young Male Rats.
• High Fat Diet Administration Leads to the Mitochondrial Dysfunction and Selectively Alters the Expression of Class 1 GLUT Protein in Mice.
• MiR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity.
• Dietary Energy Restriction Ameliorates Cognitive Impairment in a Mouse Model of Traumatic Brain Injury.
• TGF-β2 is an Exercise-induced Adipokine that Regulates Glucose and Fatty Acid Metabolism.
• Molecular Pathways Linking Adipose Innervation to Insulin Action in Obesity and Diabetes Mellitus.
• Exercise Initiated During Pregnancy in Rats Born Growth Restricted Alters Placental MTOR and Nutrient Transporter Expression.

Scientific Rigor & Scholarly Dialogue

• Change in Study Randomization Allocation Needs to Be Included in Statistical Analysis: Comment on ‘Randomized Controlled Trial of Weight Loss Versus Usual Care on Telomere Length in Women with Breast Cancer: The Lifestyle, Exercise, and Nutrition (LEAN) Study’.
• Alternating Assignment Was Incorrectly Labeled as Randomization.
• Response to Criticisms of the 20 M Shuttle Run Test: Deflections, Distortions and Distractions.
• Misleading Title of Review Paper.
• Response: Environmental Risk Factors and Interventions for Obesity.
• Do Policy Statements on Media Effects Faithfully Represent the Science?
• Best Practices in Nutrition Science to Earn and Keep the Public's Trust.
• PREDIMED and the “Corpse” of Nutrition Science.
• PREDIMED Trial of Mediterranean Diet: Retracted, Republished, Still Trusted?

Clinical

• High BMI is Associated with Lower Survival and Increased Chronic GVHD After Allogeneic Hematopoietic Stem Cell Transplantation.
• Multidisciplinary Management of Leaks After One-Anastomosis Gastric Bypass in a Single-Center Series of 2780 Consecutive Patients.
• Factors Associated with Visual Acuity and Central Subfield Thickness Changes When Treating Diabetic Macular Edema with Anti–Vascular Endothelial Growth Factor Therapy.
• RCT: Ascorbic Acid Supplementation Improves Postprandial Glycaemic Control and Blood Pressure in Individuals with Type 2 Diabetes.

Children and Adolescents

• Do Changes in Weight Status Affect Cognitive Function in Children and Adolescents with Obesity? A Secondary Analysis of a Clinical Trial.
• White Matter Integrity Disparities Between Normal-weight and Overweight/obese Adolescents: An Automated Fiber Quantification Tractography Study.
• Effect of Macronutrient Composition on Appetite Hormone Responses in Adolescents with Obesity.
• Disparities in Childhood Overweight and Obesity By Income in the United States: An Epidemiological Examination Using Three Nationally Representative Datasets.
• Does Breast Milk Adiponectin Affect BMI and Cardio-metabolic Markers in Childhood?
• Childhood Obesity: Health Policies and Interventions.
• Sedentary Behaviours and Adiposity in 10–13 Year Olds: How Long, How Much and What?
• Childhood Obesity and Diabetes: Role of Probiotics and Prebiotics.

Surgery

• Weight Regain After Bariatric Surgery-A Multicentre Study of 9617 Patients From Indian Bariatric Surgery Outcome Reporting Group.
• Changes in Lean Mass, Absolute and Relative Muscle Strength, and Physical Performance After Gastric Bypass Surgery.
• Effect of Roux-en-Y Gastric Bypass Surgery on Diabetes Remission and Complications in Individuals with Type 2 Diabetes: A Danish Population-based Matched Cohort Study.

Drugs

• Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients.
• RCT: "a significant benefit of silymarin, pioglitazone, and vitamin E in improving liver aminotransferases in patients with NAFLD after only 3 months..."

Food & Diet

• Prolonged High Fat Diet Worsens the Cellular Response to a Small, Covert-like Ischemic Stroke.
• Microbial Fermentation of Flaxseed Fibers Modulates the Transcriptome of GPR41-expressing Enteroendocrine Cells and Protects Mice Against Diet-induced Obesity.
• Vegetarians Have a Lower Fasting Insulin Level and Higher Insulin Sensitivity Compared with Matched Omnivores: A Cross-sectional Study.
• Effects of Isolated Soy Protein and Strength Exercise Training on Exercise Performance and Biochemical Profile in Postpartum Mice.
• RCT: Consumption of Cashew Nuts Does Not Influence Blood Lipids or Other Markers of Cardiovascular Disease in Humans.
• The Effect of Nuts on Markers of Glycemic Control: A Systematic Review and Meta-analysis of RCTs.
• Effect of Daily Exposure to an Isolated Soy Protein Supplement on Body Composition, Energy and Macronutrient Intake, Bone Formation Markers, and Lipid Profile in Children in Colombia.
• RCT: Ultra-processed Diets Cause Excess Calorie Intake and Weight Gain: A One-month Inpatient Trial of Ad Libitum Food Intake.
• RCT: Low-carbohydrate Diets Differing in Carbohydrate Restriction Improve Cardiometabolic and Anthropometric Markers in Healthy Adults.
• Western Diet Regulates Immune Status and the Response to LPS-driven Sepsis Independent of Diet-associated Microbiome.
• Association Between Ultraprocessed Food Consumption and Risk of Mortality Among Middle-aged Adults in France.
• Association of Dietary Macronutrient Composition and Non-alcoholic Fatty Liver Disease in an Ageing Population: The Rotterdam Study.

Caloric Restriction

• A Comparison of Dietary and Caloric Restriction Models on Body Composition, Physical Performance, and Metabolic Health in Young Mice.
• Effects of Caloric Restriction with Protein Supplementation on Plasma Protein Profiles in Middle-Aged Women with Metabolic Syndrome—A Preliminary Open Study.

Exercise & Physical Activity

• Associations of Fitness and Physical Activity with Orthostatic Responses of Heart Rate and Blood Pressure at Mid‐Life.
• Voluntary Wheel Running in the Late Dark Phase Ameliorates Diet-induced Obesity in Mice Without Altering Insulin Action.
• The Influence of 15-week Exercise Training on Dietary Patterns Among Young Adults.
• Physical Activity Among Norwegian Preschoolers Varies By Sex, Age, and Season.
• RCT: Effect of a Programme to Improve Men’s Sedentary Time and Physical Activity.
• Systematic Review: High-Intensity Interval Training in Patients with Type 2 Diabetes Mellitus.
• Fitness and BMI During Adolescence and Disability Later in Life: A Cohort Study.
• Predictors of Objectively Measured Physical Activity in 12‐month‐old Infants: A Study of Linked Birth Cohort Data with Electronic Health Records.
• Concurrent Validity of the Fitbit for Assessing Sedentary Behavior and Moderate-to-vigorous Physical Activity.
• Genetic Factors Associated with Human Physical Activity: Are Your Genes Too Tight to Prevent You Exercising?

Economics & Sociology

• Body Size and Social Status in Medieval Alba (Cuneo), Italy.
• Socioeconomic Status and the Prediction of Health Promoting Dietary Behaviours: A Systematic Review and Meta-analysis Based on the Theory of Planned Behaviour.
• ‘Just Because I’m Old It Doesn’t Mean I Have to Be Fat’: A Qualitative Study Exploring Older Adults’ Views and Experiences of Weight Management.

Epidemiology

• Overweight and Obesity Affect Clinical Assessment of Synovitis in Rheumatoid Arthritis: Comparison of Ultrasonography and Clinical Exam.
• Asthma at Mid-life is Associated with Physical Activity Limits but Not Obesity After 10 Years Using Matched Sampling in a Nationally Representative Sample.
• Household Income, Active Travel, and Their Interacting Impact on BMI in a Sample of Urban Canadians: A Bayesian Spatial Analysis.
• Seasonal Variations in the Achievement of Guideline Targets for HbA1c, Blood Pressure, and Cholesterol Among Type 2 Diabetic Patients: A Nationwide Population-Based Study (ABC Study) (JDDM49).
• Objectively Measured Physical Activity, Sedentary Behavior, and Metabolic Syndrome in Adults: Systematic Review of Observational Evidence.
• Prevalence of Optimal Metabolic Health in American Adults: National Health and Nutrition Examination Survey 2009–2016.
• Higher Dietary Vitamin C Intake is Associated with a Lower Risk of Gestational Diabetes Mellitus: A Longitudinal Cohort Study.
• Obesity and Longer Term Risks of Dementia in 65–74 Year Olds.
• Type 2 Diabetes, but Not Insulin (Analog) Treatment, is Associated with More Advanced Stages of Breast Cancer: A National Linkage of Cancer and Pharmacy Registries.
• Disentangling the Genetics of Lean Mass.
• Would the Elimination of Obesity and Smoking Reduce U.S. Racial/Ethnic/Nativity Disparities in Total and Healthy Life Expectancy?
• Changes in Screening Practices for Prediabetes and Diabetes Since the Recommendation for Hemoglobin A1c Testing.
• Sex Differences in Cardiovascular Risk Profile From Childhood to Midlife Between Individuals Who Did and Did Not Develop Diabetes at Follow-up: The Bogalusa Heart Study.
• Frailty and Risk of Fractures in Patients with Type 2 Diabetes.

Psychology & Neuroscience

• The Mediating Effect of Self-Regulation in the Association Between Poverty and Child Weight: A Systematic Review.
• RCT: Exposure therapy vs lifestyle intervention to reduce food cue reactivity and binge eating in obesity.

Equity and Disparities

• Trends and Contemporary Racial/Ethnic and Socioeconomic Disparities in US Childhood Obesity.
• Joint Associations Between Weekday and Weekend Physical Activity or Sedentary Time and Childhood Obesity.

Stigma

• Weight‐based Victimization Among Sexual and Gender Minority Adolescents: Findings From a Diverse National Sample.
• Intergenerational Association of Maternal Obesity and Child Peer Victimization in the United States.

Policy Related

• Humans Against Obesity: Who Will Win?
• Court Rules En Banc for Injunction Against San Francisco’s Health Warning Requirement for Soft Drink Ads.
• A Legal and Practical Guide for Designing Sugary Drink Taxes.
• Childhood Obesity: Can Public Policy Make a Difference?
• Changing the Irish Dietary Guidelines to Incorporate the Principles of the Mediterranean Diet: Proposing the MedÉire Diet.
• Impact of School-based Nutrition and Physical Activity Intervention on BMI Eight Years After Cessation of RCT.

Intergenerational Effects

• Maternal BMI, Gestational Weight Gain, and the Risk of Overweight and Obesity Across Childhood: An Individual Participant Data Meta-analysis.
• Altered Cord Blood Mitochondrial DNA Content and Pregnancy Lead Exposure.
• Maternal and Newborn Vitamin D–Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes.

Ecology, Evolution, & Energetics

• Gut Microbiota and Energy Homeostasis in Fish.
• Comparison of Estimated Energy Requirements Using Predictive Equations with Total Energy Expenditure Measured By the Doubly Labelled Water Method in Acute Spinal Cord Injury.
• Energetics and Thermal Adaptation in Semifossorial Pine-voles Microtus Lusitanicus and Microtus Duodecimcostatus.

Methods

• Two- vs One-hour Glucose Tolerance Testing: Predicting Prediabetes in Adolescent Girls with Obesity.
• Brief Tools to Measure Obesity-related Behaviours in Children Under 5 Years of Age: A Systematic Review.
• A Crowdsourcing Approach to Understand Weight and Weight Loss in Men.
• Spatial Technologies in Obesity Research: Current Applications and Future Promise.
• Pea-sized Pill Delivers Insulin Shot From Inside the Stomach.
• A Novel Platform for Isotype-specific Testing of Autoantibodies.

Mathematical and Quantitative

• Modeling the Effect of High Calorie Diet on the Interplay Between Adipose Tissue, Inflammation, and Diabetes.
• Modeling the Diet Dynamics of Children: the Roles of Socialization and the School Environment.

Commentary

• Is Coffee Good or Bad? A Critical View on the Science Behind It.
• Fat Cells Gobbling Up Norepinephrine?
• Educating Future Physicians in Nutritional Science and Practice: The Time is Now.
• Choosing an Accurate Outcome Metric for Pediatric Obesity Care.
• Feasting on the Mythical Magic of Breakfast.
• Another Reason GLP-1 is Important for Obesity Care.
• ‘Some Like It Hot’: Penn Museum Workshop Explores Psychology of Spices.
• Probiotic Pros and Cons.
• Vegan or Mediterranean Diet – Which is Better for Heart Health?
• Obesity and the Food Supply: Assumptions vs Facts.
• What Presidential Checkups Tell Us About Self-Reports.

General

• Doing the Right Thing: A Qualitative Investigation of Retractions Due to Unintentional Error.
• Reporting of R2 Statistics for Mixed-Effects Regression Models.
• Neighborhood Size-effects Shape Growing Population Dynamics in Evolutionary Public Goods Games.
• Evolutionary Adaptations that Enable Enzymes to Tolerate Oxidative Stress.
• Selecting Crackling Product Based on Sensory Analysis By Different Statistical Data Approaches.
• Statistical Methodology in Studies of Prenatal Exposure to Mixtures of Endocrine-Disrupting Chemicals: A Review of Existing Approaches and New Alternatives.
• The Journey to Transparency, Reproducibility, and Replicability.
• Scientific Integrity Issues in Environmental Toxicology and Chemistry: Improving Research Reproducibility, Credibility, and Transparency.
• Methods to Foster Transparency and Reproducibility of Federal Statistics.
• Americans Concerned About Their Weight, but Don’t Understand Link to Heart Conditions and Overall Health.
• The Global Syndemic of Obesity, Undernutrition, and Climate Change: The Lancet Commission Report.

Announcements

• "A $3 million gift from Chicago-based consulting and accounting firm Grant Thornton LLP will establish a new institute on the Indiana University Bloomington campus - the Grant Thornton Institute for Data Exploration for Risk Assessment and Management."
• NORC of UAB Seeks Postdoctoral Fellows in Obesity Research.
• UAB Seeks Postdoctoral Fellows for Its AHA Strategically Focused Research Center– Obesity Network: Intergenerational Transmission of Obesity.
• IU School of Public Health Bloomington Initiates Major Wave of Faculty Recruitment – Tenure-track Positions Available in Every Department and Two Department Chairs Open: See Multiple Listings Posted Here.