Featured

• An Isocaloric Moderately High-fat Diet Extends Lifespan in Male Rats and Drosophila.
• How to Make a Fitbit for an Elephant.
• Systematic Review: Effects of Whole Grain Intake, Compared with Refined Grain, on Appetite and Energy Intake.

Headline vs Study

• Headline: How Protein Bolsters COVID-19 Recovery.
• Study: A couple reviews, an expert guidance article, and this "retrospective, non-controlled, non-blinded, cross-sectional study" on l-glutamine.

Contrary or Null Findings

• Shorter Distances to Physical Activity Facilities Associated with Greater Risk of Childhood Overweight/obesity. (pdf)
• RCT: "Although this study may have been underpowered, patients with stroke NIHSS 7-42 did not benefit from in-bed cycle exercise in addition to usual care after acute stroke."
• RCT: No Significant Effect of an Eating Control and Eating Behavior Modification Treatment to Reduce Abdominal Obesity.
• RCT: Photobiomodulation 30 Min or 6 H Prior to Cycling Does Not Alter Resting Blood Flow Velocity, Exercise-Induced Physiological Responses or Time to Exhaustion in Healthy Men. (pdf)
• RCT: Branched-Chain Amino Acid Supplementation Does Not Preserve Lean Mass or Affect Metabolic Profile in Adults with Overweight or Obesity in a Weight Loss Intervention.
• High-fructose Feeding Does Not Induce Steatosis or Non-alcoholic Fatty Liver Disease in Pigs.
• NLRP3 Deficiency Did Not Attenuate NASH Development Under High Fat Calorie Diet Plus High Fructose and Glucose in Drinking Water in Mice.
• RCT: No Differential Effects of Two Types on Yoga in Weight Loss.

Basic

• Recurrent Non-severe Hypoglycemia Aggravates Cognitive Decline in Diabetes and Induces Mitochondrial Dysfunction in Cultured Astrocytes.
• Presence of Adenovirus-36 DNA in Adipose Tissue of Women: Relationship with Adipocyte Morphology and the Expression of C/EBPβ and HIF-1α.
• Dietary Alpha- and Gamma-Tocopherol (1:5 Ratio) Supplementation Attenuates Adipose Tissue Expansion, Hepatic Steatosis, and Expression of Inflammatory Markers in a High-Fat-Diet–Fed Murine Model.
• Hypothalamic Hormone-Sensitive Lipase Regulates Appetite and Energy Homeostasis.
• Adipose Tissue Lipolysis Is Regulated by PAQR11 Via Altering Protein Stability of Phosphodiesterase 4D.
• Tumor Metabolic Reprogramming by Adipokines as a Critical Driver of Obesity-Associated Cancer Progression.
• Domeless Receptor Loss in Fat Body Tissue Reverts Insulin Resistance Induced by a High-sugar Diet in Drosophila Melanogaster.

Scientific Rigor & Scholarly Dialogue

• Retraction Note: Chemopreventive Potential of Resveratrol in Mouse Skin Tumors Through Regulation of Mitochondrial and PI3K/AKT Signaling Pathways.
• Perspective: US Documentation and Regulation of Human Nutrition Randomized Controlled Trials.

Clinical

• Sex Differences in Hemoglobin A1c Levels Related to the Comorbidity of Obesity and Depression.
• Systematic Review: Methodological Issues in Assessing Change in Dietary Intake and Appetite Following Gastric Bypass Surgery.
• Intermittent Fasting: Is There a Role in the Treatment of Diabetes? A Review of the Literature and Guide for Primary Care Physicians.
• A Practical Approach to Obesity Prevention Healthy Home Habits.
• Time Restricted Eating as a Weight Loss Intervention in Adults with Obesity.
• Scoping Review: Non-Surgical Interventions for Hospitalized Adults with Class II or Class III Obesity.
• Risk of Progression to Diabetes Among Older Adults with Prediabetes.

Children and Adolescents

• Early Childhood Factors Associated with Obesity at Age 8 in Vietnamese Children.
• Human Milk Hormone Intake in the First Month of Life and Physical Growth Outcomes in Preterm Infants.
• The Association between Executive Functions and Body Weight/BMI in Children and Adolescents with ADHD.
• Meta-Analysis: How Many US Children and Adolescents with Overweight and Obesity Could Improve Their Percent Body Fat by Exercising?
• Meta-Analysis: Relationship between Formula Milk and the Incidence Obesity in Children Under Five.
• Meta-Analysis: Prevalence of Childhood Obesity in Brazil.
• Maternal Obesity Influences Birth Weight More Than Gestational Diabetes.

Surgery

• Review: Weight Regain and Insufficient Weight Loss After Bariatric Surgery: Definitions, Prevalence, Mechanisms, Predictors, Prevention and Management Strategies, and Knowledge Gaps.
• Scoping Review: Weight Regain and Insufficient Weight Loss After Bariatric Surgery: Definitions, Prevalence, Mechanisms, Predictors, Prevention and Management Strategies, and Knowledge Gaps.
• DSM 5 Lifetime Psychiatric Diagnoses in Two Bariatric Surgery Programs.

Drugs

• RCT: Once-Weekly Semaglutide in Adults with Overweight or Obesity.
• RCT: Effects of Oral Semaglutide on Energy Intake, Food Preference, Appetite, Control of Eating and Body Weight in Subjects with Type 2 Diabetes.

Food & Diet

• Food After the COVID-19 Pandemic and the Case for Change Posed by Alternative Food: A Case Study of the American Midwest. (pdf)
• Rice Bran Oil Attenuates Chronic Inflammation by Inducing M2 Macrophage Switching in High-Fat Diet-Fed Obese Mice.
• Association of Some Dietary Ingredients, Vitamin D, Estrogen, and Obesity Polymorphic Receptor Genes with Bone Mineral Density in a Sample of Egyptian Women with Obesity.
• Review: Health Benefits of Plant-Based Nutrition: Focus on Beans in Cardiometabolic Diseases.
• RCT: A Mediterranean Diet and Low-Fat Vegan Diet to Improve Body Weight and Cardiometabolic Risk Factors.
• Consumption of Foods with Higher Energy Intake Rates Is Associated with Greater Energy Intake, Adiposity, and Cardiovascular Risk Factors in Adults.
• Causal Relationship between Dietary Macronutrient Composition and Anthropometric Measures: A Bidirectional Two-sample Mendelian Randomization Analysis.

Caloric and Dietary Restriction

• Dietary GABA and Its Combination with Vigabatrin Mimic Calorie Restriction and Induce Antiobesity-like Effects in Lean Mice.
• Caloric Restriction Following Early-Life High Fat-Diet Feeding Represses Skeletal Muscle TNF in Male Rats.
• Two-Meal Caloric Restriction Induces 12-Hour Rhythms and Improves Glucose Homeostasis.

Exercise & Physical Activity

• Meta-Analysis: Movement Is Improvement: The Therapeutic Effects of Exercise and General Physical Activity on Glycemic Control in Patients with Type 2 Diabetes Mellitus.
• Added Body Mass Alters Plantar Shear Stresses, Postural Control, and Gait Kinetics: Implications for Obesity.

Economics & Sociology

• What Is the Causal Effect of Income Gains on Youth Obesity? Leveraging the Economic Boom Created by the Marcellus Shale Development.
• Association of Long-Term Trajectories of Neighborhood Socioeconomic Status with Weight Change in Older Adults.
• Systematic Review: The Association between Adverse Childhood Experiences and Childhood Obesity.

Epidemiology

• Associations between the Built Environment and Obesity: An Umbrella Review.
• Impact of Waist Circumference on the Risk of Vertebral Fracture: A Nationwide Cohort Study in South Korea.
• Weight Change and Mental Health According to Obesity in Relatively Healthy Middle-aged Korean Women.
• BMI Trajectories and the Risk for Alzheimer’s Disease Among Older Adults.
• Causal Effects of Relative Fat, Protein, and Carbohydrate Intake on Chronic Kidney Disease: A Mendelian Randomization Study.
• Gender Differences in Obesity-Related Cancers.

Psychology & Neuroscience

• Effect of Behavioral Therapy with In-Clinic or Telephone Group Visits vs In-Clinic Individual Visits on Weight Loss Among Patients with Obesity in Rural Clinical Practice.
• Meta-Analysis: Executive Functions in Predicting Weight Loss and Obesity Indicators.
• Variants in Circadian Rhythm Gene Cry1 Interacts with Healthy Dietary Pattern for Serum Leptin Levels: A Cross-sectional Study.
• Alterations in Reward Network Functional Connectivity are Associated with Increased Food Addiction in Individuals with Obesity.
• Review: Hypothalamic Inflammation as a Potential Pathophysiologic Basis for the Heterogeneity of Clinical, Hormonal, and Metabolic Presentation in PCOS.
• Serotonin, Food Intake, and Obesity.
• Obesity and Brain Vulnerability in Normal and Abnormal Aging: A Multimodal MRI Study.
• The Concept of “Food Addiction” Helps Inform the Understanding of Overeating and Obesity: Debate Consensus.

Equity and Disparities

• Substance Use, Mental Health and Weight-Related Behaviours During the COVID-19 Pandemic in People with Obesity.
• Does Inequality Have a Silver Lining? Municipal Income Inequality and Obesity in Mexico.

Stigma

• Associations between Experience of Early Childhood Trauma and Impact on Obesity Status, Health, as Well as Perceptions of Obesity-Related Health Care.
• Obesity and the Receipt of Prescription Pain Medications in the US.

Policy Related

• The Obesity Paradigm and the Role of Health Services in Obesity Prevention: A Grounded Theory Approach.
• Trends in Total and Out-of-pocket Payments for Noninsulin Glucose-Lowering Drugs Among U.S. Adults with Large-Employer Private Health Insurance from 2005 to 2018.

Intergenerational Effects

• Maternal Obesity Increases the Risk of Fetal Cardiac Dysfunction Via Visceral Adipose Tissue Derived Exosomes.
• Adiposity Associated DNA Methylation Signatures in Adolescents are Related to Leptin and Perinatal Factors.

Ecology, Evolution, & Energetics

• Cardiorespiratory Adjustments to Chronic Environmental Warming Improve Hypoxia Tolerance in European Perch (Perca Fluviatilis).
• Dramatic Changes in Mitochondrial Substrate Use at Critically High Temperatures: A Comparative Study Using Drosophila.

Methods

• Protocol: 'Tracking Together’—Simultaneous Use of Human and Dog Activity Trackers: Protocol for a Factorial, Randomized Controlled Pilot Trial.
• Systematic Review: Use of the Healthy Eating Index in Intervention Studies for Cardiometabolic Risk Conditions.

Commentary

• All Food Processes Have a Residual Risk, Some are Small, Some Very Small and Some are Extremely Small: Zero Risk Does Not Exist.
• Food Choice and Personal and Global Health.
• Metabolic Strategies for Inhibiting Cancer Development.
• Ultraprocessed Foods and Cardiovascular Health: It's Not Just About the Nutrients.
• Don't Feed the Ghosts in Your Metabolic Machine.
• Lawsuit Challenging FDA Approval of Novel Genetically Engineered Color Additive that Makes Impossible Burger "Bleed" Moves Forward.
• NIH's ‘Precision Nutrition’ Bet Aims for Individualized Diets.
• Cast in Amber: Before and After Weight Loss.

General

• “Important Conversations” are Needed to Explain the Nocebo Effect.
• Aging-US: Sulforaphane Promotes C. Elegans Longevity and Healthspan.
• Maternal Care According to Offspring Sex and Maternal Physical Condition in Mantled Howler Monkeys (Alouatta Palliata). (pdf)
• Sexual Size Dimorphism and Its Allometry in Chinese Lizards. (pdf)
• National Institute on Aging Workshop Repurposing Drugs or Dietary Supplements for Their Senolytic or Senomorphic Effects: Considerations for Clinical Trials.
• RCT: Recovery of the Decline in Activities of Daily Living After Hospitalization Through an Individualized Exercise Programme.
• Cognitive Scientists are Going to the Dogs Unleashing a New Breed of Research into Co-evolution and the Aging Brain.
• The Goal of Geroscience Is Life Extension.

Announcements

• Seven New Members Add Extraordinary Talent to IUB SPH Dean's Advisory Board.
• Promising Mid-career Researchers Preselected for Their Pioneering and Collaborative Approach on Alimentation.
• Symposium of the Midwest Aging Consortium--February 18.
• Non-Tenure-Track: Clinical Full-Associate-Assistant Professor; Senior Lecturer or Lecturer Search.
• Nutrition Science Tenure/Tenure-Track: Full Professor/Associate-Assistant Professor Search.