Featured

• Developing Count Regression Techniques for Predicting the Number of New Type 2 Diabetes Cases in Saudi Arabia.
• Podcast: Featuring Dr. Kevin Hall - EP 75: GLP-1 Trend Gets Hotter, Rethinking UPF Myths and Mechanisms.
• Review: Creatine Supplementation and the Brain: Have We Put the Cart Before the Horse?
• RCT: Effects of Minimally Processed Red Meat Within a Plant-Forward Diet on Biomarkers of Physical and Cognitive Aging.
• RCT: "Compared with poultry, consumption of beef for 28 d did not produce adverse effects on pancreatic β-cell function, other indicators of glucose homeostasis, lipoprotein lipids, or biomarkers of inflammation."

Headline Vs. Study

• Headline: "Study reveals new pre-meal hack that could help keep you thin….Experts found sniffing a meal prior to tucking in could trigger a feeling of fullness that may help prevent people from overeating."
• Study: A food-sensitive olfactory circuit drives anticipatory satiety… in mice.

Contrary or Null Findings

• "A prepregnancy lifestyle intervention did not influence childhood weight trajectory."
• Preprint: "Contrary to the common belief, DST [Daylight Savings Time] transitions produced no net change in total daily steps."
• Report: "Contrary to expectations, ERI [ethnic racial identity] centrality predicted less physical activity and nutrition, and ERI negative affect predicted better nutrition."
• "Contrary to our initial hypothesis, CASP-1 gene expression was significantly higher in non-PCOS participants across all adipose depots examined."
• ”Contrary to expectations, a greater fermented food variety was associated with poorer psychological well-being.”
• "Contrary to the hypothesis, cognitive performance remained largely unaffected by exercise-induced dehydration and thermal strain."
• Omega-3 Fatty Acid Supplementation Does Not Attenuate Declines in Skeletal Muscle Mitochondrial Area in Young, Healthy Females During Immobilization.
• RCT: No Effect of High-Amylose Maize Starch on Pre- or Postexercise Hydration Status, Thermophysiological Strain, or Exhaustive Exercise Performance During Exertional Heat Stress in Endurance Runners.

Basic

• EBF2 Variant Identified in a Patient with Atypical Partial Lipodystrophy Causes Adipose Fibrosis and Dysfunction.
• Kiss1-FASN Participates in Fatty Acid Synthesis Via High-Fat Diet in PgVAT of Female Mice.
• RSK2 Facilitates Beige Fat Formation Through Thermogenic and Glycolytic Pathways.
• Perivascular Adipose Tissue from Female Rats Fed a High-Fat Diet Impaired Mesenteric Artery Vasodilation.
• The Protein Denitrosylase SCoR2 Regulates Lipogenesis and Fat Storage.

Scientific Rigor & Scholarly Dialogue

• Expression of Concern: “Plaque Begets Plaque. ApoB Does Not: Longitudinal Data from the KETO-CTA Trial”.
• PubPeer Comments On: Efficacy of Oral Folinic Acid Supplementation in Children with Autism Spectrum Disorder: A Randomized Double-Blind, Placebo-Controlled Trial.
• Retraction: Efficacy of Oral Folinic Acid Supplementation in Children with Autism Spectrum Disorder: A Randomized Double-Blind Placebo-Controlled Trial.

Clinical

• Review: Addressing Micronutrient Requirements in Type 2 Diabetes: An International Consensus Report.
• RCT: Remission of Impaired Glucose Tolerance by Anthocyanin Supplementation.
• Meal Fatty Acid Metabolism Is Associated with Long-Term Weight Gain in Women - A Retrospective Cohort Study.
• Heterogeneity in Treatment Outcomes After a Multicomponent Weight Loss Intervention in Older Adults with Obesity.

Children and Adolescents

• Review: Psychosocial Outcomes Reported in Randomized Behavioral Intervention Trials for Children and Adolescents with Overweight and Obesity.
• Building Healthier Childhoods in Barrie, Canada: A Data-Guided, Community-Led Framework for City-Scale Behaviour Change.
• The Trajectories of Bioelectrical Impedance Analysis-Derived Raw Variables (Phase Angle and Impedance Ratio) in Healthy Italian Children and Adolescents.
• Meta-Analysis: Sedentary Behavior and Low Back Pain in Children and Adolescents.

Surgery

• Long-Term Real-World Body Weight Responses to Liraglutide or Bariatric Surgery in Adolescents with Obesity.
• Metabolic and Bariatric Surgery Among Patients with Social Anxiety Disorder.
• Review: Management of the Kidney Transplant Candidate with Obesity.
• Last Resort in Obesity: Sleeve Gastrectomy.
• Cohort Study: Association between Bariatric Surgery and the Long-Term Risk for Venous Thromboembolism.
• Cohort Study: Impact of Multidisciplinary Steatotic Liver Disease Management on Bariatric Surgery Referral and Clinical Outcomes.

Drugs

• Beyond the Weight Loss: The Effects of Semaglutide on Standard and Diet-Induced Obese Mice.
• Preprint: Effects of Liraglutide on Gut Bacterial Community Dynamics.
• A Case of Euglycemic Diabetic Ketoacidosis with Tirzepatide Use and Severe Calorie Restriction.

Food & Diet

• Association between Low-Carbohydrate Diets and 10-Year Atherosclerosis Cardiovascular Disease Risk: Data from the National Health and Nutrition Examination Survey.
• IFIC Spotlight Survey: Americans’ Perceptions of Fiber & Whole Grains.
• RCT: Cholesterol-Lowering Effects of Oats Induced by Microbially Produced Phenolic Metabolites in Metabolic Syndrome.

Caloric and Dietary Restriction

• Evaluation of the Effect of Different Intermittent Fasting Regimens on Metabolic Parameters in Healthy Male Wistar Rats.
• RCT: Alteration in Amino Acid Metabolism After Isocaloric, Energy-Restricted Ketogenic Diet in Women with Overweight and Obesity.
• RCT: Metabolic and Orexin-A Responses to Ketogenic Diet and Intermittent Fasting Over 12 Months in Adults with Obesity.
• The Effect of Continuous or Intermittent Calorie-Restricted Diet on Body Composition and Resting Energy Expenditure in Patients with Type 2 Diabetes.
• Preprint: Changes in Leptin Gene Expression and Receptor in Aged Male Rats Following Continuous Training with and Without Calorie Restriction.

Exercise & Physical Activity

• Exercise Alleviates the Obesity-Related Dysfunction of Skeletal Muscle and Heart Caused by Akh Gene Knockdown in Drosophila.
• Assessing Genetic Risk for Physical Activity and Its Interaction with Diet in Predicting Activity Levels and Weight Loss in the IMPROVE Study.
• Meta-Analysis: Accelerometer-Measured Physical Activity Among Children and Adolescents with and without Neurodevelopmental Disorders.
• Sedentary Behavior and Physical Health Status Explain the Relationship between Years of Residence in Socioeconomically Distressed Counties and Risk for Cardiovascular Diseases.

Economics & Sociology

• Social Capital and Obesity: A Longitudinal Study Among Older Adults After Relocation for Poverty Alleviation in China.
• Trends and Socio-Economic Inequalities in Overweight- and Obesity-Related Premature Cardiovascular Disease Mortality in Australia.
• Systematic Review: Differentiating the Abnormalities of Food and Monetary Reward Cue Processing Associated with Overweight/Obesity.
• Estimation of Direct and Indirect Costs Associated with Obesity Treatment Interventions Among Adult Populations in Iran.

Epidemiology

• Association between Nutrition Literacy and Hypertension Control: Chain Mediating Association of Diet-Control Intention and Salt-Restriction Tools Utilization.
• What Happens Beyond the Excess Weight Threshold? Evidence from Adult Women in India.
• Prevalence and Associated Factors of Normal-Weight Central Obesity Among Community-Dwelling Adults 18 Years and Older in Mongolia.

Psychology & Neuroscience

• Emotional Eating Associated with Poor Body Satisfaction in Women with Obesity: Theory-Based Psychosocial Mediators in Weight Management Treatment.
• Cohort Study: Association of Mild Cognitive Impairment and Obesity-Metabolic Status in Middle-Aged and Elderly Adults.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• US State-Level Prevalence of Adult Obesity by Race and Ethnicity from 1990 to 2022 and Forecasted to 2035.
• Overweight & Obesity Epidemic, Temporal Trends and Regional Disparities in Physical Growth of Vietnamese Children.

Ethics

• The Ethics of Wegovy [Semaglutide] in Pediatric Mental Health.

Stigma

• Perceptions and Stigma of Anti-Obesity Pharmacotherapy in Adult Polish Women.
• The Relationship between Internalized Weight Stigma and Acceptance of Weight-Loss Treatment Resources.
• The Association between Stigma Consciousness and Weight Stigma, Psychological Well-Being, Positive Body Image, and Eating Behaviors.

Policy Related

• Exploring Ultra-Processed Food Consumption: Adherence to Food-Based Dietary Guidelines, Nutrient Intake and the Associated Greenhouse Gas Emissions in Iceland.
• Qualitative: Perspectives on Surveilling Policy, Systems, and Environmental Change Impacts of Health-Promoting Behaviors in Rural Communities.
• Comparison of Food Processing Classification Frameworks in the National Health and Nutrition Examination Survey (NHANES) 2017 - 2018.
• Student Perceptions of School Lunch and Their Association with Self-Reported Participation in School Meal Programs.
• Water Is K’é: Pilot Results of a Community-Based Intervention to Increase Healthy Beverage Consumption by Navajo Preschool Children.
• Commentary: Changes to SNAP Under HR 1 and the Implications for Food Insecurity.

Intergenerational Effects

• Gestational Weight Gain and Early Child Neurodevelopment: Prospective Cohort Study.
• Meta-Analysis: The Neonatal Line in Primary Teeth: A Systematic Review and Meta-Analysis of Its Forensic, Clinical, Anthropological, and Archaeological Applications.
• YAP/TAZ-VGLL3 Governs Adipocyte Fate Via Epigenetic Reprogramming of PPARγ and Its Target Enhancers.
• Impact of Maternal Fasting Blood Glucose in Pregnancy on Body Composition, Anthropometric, and Metabolic Outcomes in Newborns and 3-Year-Old Offspring: Results from the Lifestyle in Pregnancy and Offspring Study.

Ecology, Evolution, & Energetics

• Body Condition Among Svalbard Polar Bears Ursus maritimus During a Period of Rapid Loss of Sea Ice.
• A Polysaccharide from Artocarpus heterophyllus Lam. Pulp Ameliorates Oxidative Stress and Lipid Accumulation in HepG2 Cells.
• Review: Blood-Based Obesity Biomarkers and Their Relevance for Disease Risk.
• Understanding Insulin Resistance in Osteosarcopenic Obesity: Therapeutic Approaches for Prevention and Management.
• Schisantherin a Interacts with Gut Bacteria to Stimulate Adipose Tissue Thermogenesis in Obese Mice Via a TGR5-p-CREB-STAT6 Signaling Pathway.

Methods

• Review: Artificial Intelligence and Big Data in Predicting and Managing Obesity‑Associated Diabetes.
• Book: Next-Gen Diagnostics: Utilizing AI Classification Algorithms for Enhanced Obesity Detection and Intervention.

Mathematical and Quantitative

• Preprint: Investigating the Impact of Obesity as an Immunological Instigator on Young-Onset Arthritis Using Perturbation-Based Simulation.
• Prediction Models for Early Identification of Overweight and Obesity in Children - A National Study.

Commentary

• Podcast: The Seed Oil Debate: Are They Uniquely Harmful Relative to Other Dietary Fats? | Layne Norton, Ph.D.
• Podcast: Looking Beyond Statins for New Ways to Lower Cholesterol.
• Combination Therapy for Low-Density Lipoprotein (LDL) Cholesterol Lowering in Hypercholesterolemia.
• Podcast: How Much Protein Is Actually Healthy? - Eric Helms, PhD & Matt Nagra, ND.
• A Nutrition Science Student's Take on the New Dietary Guidelines for Americans.
• No Longer, Voice: A Closer Look at Food Noise.
• Roche Hopes to Leap Past Lilly with a New Dual Agonist.
• Linking Dietary Patterns to Alzheimer's Disease Biomarkers with Network Mathematical Modeling Could Enable New Approach Methodologies in Preventative AD Research: A Narrative Interdisciplinary Review.

General

• Scientists Inch Closer to Solving the ‘Kissing Disease’ Mystery.
• Meta-Analysis: Camel Hump Oil and Milk Vs. Plant-Based Oils in Aging-Related Oxidative Stress and Inflammation.
• Biomarkers of Foraging and Reproduction in Captive Adult Female Hawksbill Sea Turtles (Eretmochelys imbricata).
• Antioxidant and Energy Supplementation Alleviate Oxidative Stress and Enhance Milk Production Through Modulation of Hepatic Antioxidant Gene Expression in Transition Dromedary Camels.
• Sensory Characterization of Cookies with Sugar Replacement by Sweeteners Using the Check-All-That-Apply (CATA) Method.
• Gastrointestinal Catastrophe After Ingestion of Liquid Nitrogen-Treated Candy: A Case of Dragon’s Breath-Induced Perforation and Postoperative Complications.
• The Road to Cancer Care: Understanding How Far Owners Travel for Their Pets' Oncology Treatment.

Announcements

• Webinar: Advancing Obesity Care: Leveraging Evidence-Based Medicine and Shared Decision-Making for Effective Weight Management.