Featured

• Exercise Preserves Physical Fitness During Aging Through AMPK and Mitochondrial Dynamics.
• Lifespan Extension in Female Mice by Early, Transient Exposure to Adult Female Olfactory Cues.
• Past History of Obesity Triggers Persistent Epigenetic Changes in Innate Immunity and Exacerbates Neuroinflammation.
• Ants Live 10 Times Longer by Altering Their Insulin Responses.

Headline vs Study

• Headline: Study Reveals What Triggers Our Brains to Overeat.
• Study: CRTC1 Deficiency, Specifically in Melanocortin-4 Receptor-Expressing Cells, Induces Hyperphagia, Obesity, and Insulin Resistance... In Mice.

Contrary or Null Findings

• RCT: "Contrary to our a priori hypotheses, children enrolled in intervention programs demonstrated a small, yet statistically significant, mean increase in BMIz and modified BMIz per year beyond that experienced by children enrolled at control programs, after controlling for key confounders..."
• RCT: "For infants born through cesarean delivery, vaginal seeding has no significant impacts on the gut microbiota, growth, or allergy risks during the first 2 years of life."
• Thermoneutral Housing and Preexisting Obesity Do Not Abolish the Sexually Dimorphic Effects of Olanzapine on Weight Gain in Mice.
• Acute Hypoxia Does Not Alter Mitochondrial Abundance in Naked Mole-Rats.
• RCT: Resistance Training Volume Does Not Influence Lean Mass Preservation During Energy Restriction in Trained Males.
• RCT: Personalized Dietary Advice to Increase Protein Intake in Older Adults Does Not Affect the Gut Microbiota, Appetite or Central Processing of Food Stimuli in Community-Dwelling Older Adults.
• Muscle Fiber Type Grouping Does Not Change in Response to Prolonged Resistance Exercise Training in Healthy Older Men.
• "Contrary to our assumption, a history of abuse was not associated with the absence of recovery of EDBE [eating disorders with episodes of binge eating] at 1 year."

Basic

• Profiling Mouse Brown and White Adipocytes to Identify Metabolically Relevant Small ORFs and Functional Microproteins.
• Increased Adipose Catecholamine Levels and Protection from Obesity with Loss of Allograft Inflammatory Factor-1.
• Inhibition of the Endocannabinoid System Reverses Obese Phenotype in Aged Mice and Partly Restores Skeletal Muscle Function.
• Inflammation Biomarkers and Inflammatory Genes Expression in Metabolically Healthy Patients with Obesity.
• Hepatocyte PPARγ Contributes to the Progression of Non-Alcoholic Steatohepatitis in Male and Female Obese Mice.
• Exosomal MiR-27b-3p Secreted by Visceral Adipocytes Contributes to Endothelial Inflammation and Atherogenesis.
• MiRNAs as Cornerstones in Adipogenesis and Obesity.

Scientific Rigor & Scholarly Dialogue

• Article: Effect of Behavioral Activation on Time and Frequency Domain Heart Rate Variability in Older Adults with Subthreshold Depression: A Cluster Randomized Controlled Trial in Thailand.
• Letter: Only One Cluster Per Condition Is an Invalid Design for a Cluster Randomized Trial and Should Be Re‑labeled a Quasi‑experimental Study. Response To: “Effect of Behavioral Activation on Time and Frequency Domain Heart Rate Variability in Older Adults with Subthreshold Depression: A Cluster Randomized Controlled Trial in Thailand”.

Clinical

• Medical Nutrition Therapy Interventions Provided by Dietitians for Adult Overweight and Obesity Management: An Academy of Nutrition and Dietetics Evidence-Based Practice Guideline.
• Biochemical and Molecular Biomarkers: Unraveling Their Role in Gestational Diabetes Mellitus.
• Imaging Subclinical Coronary Atherosclerosis to Guide Lipid Management, are We There Yet?
• Meta-Analysis: What Is the Impact of Vitamin D Supplementation on Glycemic Control in People with Type-2 Diabetes.
• Feasibility Study: The Gestational Diabetes Future Diabetes Prevention Study (GODDESS).

Children and Adolescents

• American Academy of Pediatrics Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents with Obesity.
• The Association between Perinatal Factors and Cardiometabolic Risk Factors in Children and Adolescents with Overweight or Obesity.
• RCT: Effects of a Novel Infant Formula on Weight Gain, Body Composition, Safety and Tolerability to Infants: The INNOVA 2020 Study.
• Meta-Analysis: Cord Blood Epigenome-Wide in Six European-Based Child Cohorts Identifies Signatures Linked to Rapid Weight Growth.
• Catch-Up Growth as a Risk Factor for Rapid Weight Gain, Earlier Menarche and Earlier Pubertal Growth Spurt in Girls Born Small for Gestational Age (SGA).

Surgery

• Identifying Barriers to Shared Decision-Making About Bariatric Surgery in Two Large Health Systems.
• Change in Medial Frontal Cerebral Metabolite Concentrations Following Bariatric Surgery.
• Self-Worth and Developmental Outcomes in Young Adults After Pediatric Bariatric Surgery.

Drugs

• RCT: Effects of Initial Combinations of Gemigliptin Plus Metformin Compared with Glimepiride Plus Metformin on Gut Microbiota and Glucose Regulation in Patients with Type 2 Diabetes and Obesity.
• Meta-Analysis: Effect of SGLT-2 Inhibitors on Body Composition in Patients with Type 2 Diabetes Mellitus.
• RCT: Effect of β2-Agonist Treatment on Insulin-Stimulated Peripheral Glucose Disposal in Healthy Men.

Food & Diet

• RCT: Effect of a Plant-Based vs Omnivorous Soul Food Diet on Weight and Lipid Levels Among African American Adults.
• Update on Anti-Inflammatory Molecular Mechanisms Induced by Oleic Acid.
• RCT: A Real-World Efficacy Trial Testing Carbohydrate Restriction on Body Weight and Glycemic Control in Individuals with Type 2 Diabetes.
• RCT: Effect of Alternate Day Fasting Combined with Aerobic Exercise on Non-Alcoholic Fatty Liver Disease.

Caloric and Dietary Restriction

• Trans-10, Cis-12 Conjugated Linoleic Acid- and Caloric Restriction-Mediated Upregulation of CNDP2 Expression in White Adipose Tissue in Rodents, with Implications in Feeding and Obesity.
• Intrinsic Cardiorespiratory Fitness Modulates Clinical and Molecular Response to Caloric Restriction.

Exercise & Physical Activity

• The Effect of Interactions between BMI and Sustained Depressive Symptoms on Knee Osteoarthritis over 4 Years: Data from the Osteoarthritis Initiative.
• Trends in Means and Distributional Characteristics of Cardiorespiratory Endurance Performance for Italian Children (1984–2010).
• The Impact of Physical Exercise on Obesity in a Cohort of Southern Italian Children with Obesity: Improvement in Cardiovascular Risk and Immune System Biomarkers.
• Acute Effects of a Single Moderate-Intensity Exercise Bout Performed in Fast or Fed States on Cell Metabolism and Signaling: Comparison between Lean and Obese Rats.
• RCT: Assessment of Oxidative Stress Indices and Total Phenolics Concentrations in Adult Women with Obesity—The Effect of Training with Supplemental Oxygen.

Economics & Sociology

• The Changing Food Environment and Neighborhood Prevalence of Type 2 Diabetes.
• Associations between the Food Environment and Food and Drink Purchasing Using Large-Scale Commercial Purchasing Data.
• Glucagon Prescribing and Costs Among U.S. Adults with Diabetes, 2011–2021.

Epidemiology

• BMI and Cognition: Associations Across Mid- to Late-Life and Gender Differences.
• Risk of Esophageal and Gastric Cancer After Bariatric Surgery.
• Meta-Analysis: Weight Variability and Cardiovascular Outcomes.
• A Comprehensive Review on Prevalence, Pathogenesis, Clinical Outcomes, and Treatment of Nonalcoholic Fatty Liver Disease in Individuals with and without Obesity.
• Prevalence of At-Risk NASH and Its Association with Metabolic Syndrome in US Adults with NAFLD, 2017–2018.

Psychology & Neuroscience

• Childhood Environment and Adulthood Food Addiction: Testing the Multiple Mediations of Life History Strategies and Attitudes Toward Self.
• The Impact of Psychological Distress on Weight Regain in Post-Bariatric Patients During the COVID-19 Pandemic: A Latent Profile Analysis.
• Association of BMI and Dietary Intake with Mild Cognitive Impairment and Dementia: A Retrospective Cohort Study.
• Association of Obesity, Suicide Behaviors, and Psychosocial Wellness Among Adolescents in the United States.

Equity and Disparities

• Neighborhood Deprivation and Residential Property Values Do Not Affect Weight Loss at 1 or 3 years After Bariatric Surgery.
• The Impact of Social Determinants of Health on Obesity and Diabetes Disparities Among Latino Communities in Southern California.
• Perinatal Outcomes of Young Adolescent Pregnancies in an Urban Inner-City.
• Racial Disparities in Methylation of NRF1, FTO, and LEPR Gene in Childhood Obesity.
• A Prospective, Longitudinal Analysis of Household Income, Cortisol, and Obesity During Early Childhood.

Ethics

• Ethics of Bariatric Surgery in Adolescence and Its Implications for Clinical Practice.

Stigma

• School Nurses’ Experience of Communicating Growth Data and Weight Development to Parents of Children 8 and 10 Years of Age.
• The Prevalence and Practice Impact of Weight Bias Among New Zealand Registered Dietitians.

Policy Related

• Unhealthy Food and Beverage Marketing to Children on Digital Platforms in Aotearoa, New Zealand.
• Using Social Media to Collect Dietary Information for Public Health Policy.
• Food Insecurity in the Rural United States: An Examination of Struggles and Coping Mechanisms to Feed a Family Among Households with a Low-Income.
• Are Sub-Saharan African National Food and Agriculture Policies Nutrition-Sensitive? A Case Study of Ethiopia, Ghana, Malawi, Nigeria, and South Africa.

Intergenerational Effects

• Meta-Analysis: Gestational Weight Gain and Small for Gestational Age in Women with Obesity.
• Pre-Pregnancy BMI Has Greater Influence on Newborn Weight and Perinatal Outcome Than Weight Control During Pregnancy in Women with Obesity.
• Prevalence and Predictors of Breastfeeding Duration of 24 or More Months.
• Does Maternal Low-Dose Cadmium Exposure Increase the Risk of Offspring to Develop Metabolic Syndrome and/or Type 2 Diabetes?
• Defining Poor Growth and Stillbirth Risk in Pregnancy for Infants of Mothers with Overweight and Obesity. (pdf)
• Breastfeeding and Post-Perinatal Infant Deaths in the United States, a National Prospective Cohort Analysis.
• Cross-Sectional and Longitudinal Associations between Family Meals Frequency and Children's Overweight/Obesity in Families at High Risk of Type 2 Diabetes.

Ecology, Evolution, & Energetics

• Central Adiponectin Signaling – a Metabolic Regulator in Support of Brain Plasticity.
• Role of Mitochondria-Associated Endoplasmic Reticulum Membranes in Insulin Sensitivity, Energy Metabolism, and Contraction of Skeletal Muscle.

Methods

• Methodological Advancements in Organ-Specific Ectopic Lipid Quantitative Characterization: Effects of High Fat Diet on Muscle and Liver Intracellular Lipids.
• A Mixed-Methods Analysis of a WIC and Primary Care Partnership to Promote Responsive Feeding for Infants in Group Well-Child Care.
• Real-Time Versus Retrospective Self-Report Assessment of Loss-Of-Control Eating in Adults Undergoing Bariatric Surgery.
• Validation of Diet ID in Predicting Nutrient Intake Compared to Dietary Recalls, Skin Carotenoid Scores, and Plasma Carotenoids in University Students.

Commentary

• Reducing Negative Self-Talk with Dietary Folate.
• Obesity Guideline for Youth Draws Global Interest.
• The Obesity-Industrial Complex, in a Communal Blind Spot.
• New Guidelines for Treating Childhood Obesity Include Medications and Surgery for First Time.
• Obesity Confers Macrophage Memory.
• An Update on Peptide-Based Therapies for Type 2 Diabetes and Obesity.
• Obesity, Cancer, and Health Equity.
• Management of Obesity Across Women's Life Course: FIGO Best Practice Advice.

General

• "Scientists like Barzilai are on a quest to further increase not just lifespan but also healthspan..."
• The Hoarder - Living amidst a spectacle of untidiness.
• In-Person Classroom Instruction and Risk of SARS-CoV-2 Infection Among Undergraduates at Indiana University, Fall 2020.
• Is Mobile Gaming a New Pillar of Esports? Exploring Players' In-Game Purchases in PC and Mobile Platforms by Using Flow and Clutch.
• Canine Model of Human Frailty: Adaptation of a Frailty Phenotype in Older Dogs.
• Gene Therapy Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice.
• Burmese Pythons in Florida: A Synthesis of Biology, Impacts, and Management Tools.
• Non-Caffeine Components of Coffee and Their Effects on Neurodegenerative Diseases.
• Reproducibility and Scientific Integrity of Big Data Research in Urban Public Health and Digital Epidemiology: A Call to Action.

Video & Audio

• Optimizing Health from the Inside Out: How Daily Stress Impacts Patients Struggling with Weight.

Announcements

• IU Bloomington School of Public Health Seeks Chair of the Department of Environmental and Occupational Health.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Indiana University School of Public Health-Bloomington Is Recruiting for Tenure-Track Faculty in Every Department!