Featured

• Optogenetic Rejuvenation of Mitochondrial Membrane Potential Extends C. elegans Lifespan.
• FTC States: "As a general matter, substantiation of health-related benefits will need to be in the form of randomized, controlled human clinical testing to meet the competent and reliable scientific standard."
• 2023 Fitness Trends from around the Globe. (pdf)
• The ‘Breakthrough’ Obesity Drugs That Have Stunned Researchers.

Headline vs Study

• Headline: Study Shows Gardening May Help Reduce Cancer Risk, Boost Mental Health.
• Study: RCT: Two of Seven Registered Primary Outcomes (Zero of 14 Registered Timepoint Comparisons) Reported as Statistically Significant in Study of Gardening versus Wait-List Control. Cancer Risk Was Not an Outcome. Mental Health Measures Were Secondary Outcomes.
• Study Registration: Community Activation for Prevention (CAPs): A Study of Community Gardening (CAPs).

Contrary or Null Findings

• RCT: "We found no significant time-by-intervention interactions for combined fruit and vegetable intake, Healthy Eating Index …, sedentary time, BMI, and waist circumference (all p>0·04)...[in] Effects of a community gardening intervention on diet, physical activity, and anthropometry outcomes in the USA..."
• RCT: "We found no significant improvement in body mass index, cognition, psychopathology, antipsychotic adverse effects, or oxidative stress and inflammation in the experimental group compared with placebo...[in]...α-Lipoic Acid as Adjunctive Treatment for Schizophrenia."
• RCT: "We did not show evidence of the benefit of metformin for children of women with overweight or obesity during pregnancy".
• RCT: "In school-aged children in this study with low baseline vitamin D status, oral vitamin D3 supplementation at a dose of 14 000 IU per week for 3 years was effective in elevating 25(OH)D concentrations but did not influence growth, body composition, or pubertal development."
• RCT: "Descriptive quantity and frequency norms did not result in a stronger intention to consume healthy snacks in the upcoming week, but they did result in lower-calorie snack choices when people were asked to select three snacks that they planned to eat on the following day."
• RCT: "contrary to prior results in LLD, lean muscle mass was not associated with depression severity or outcome."
• Stress Does Not Lead to Loss of Self-Control in Eating Disorders.
• "Metabolic disturbances of patients with PCOS without hyperandrogenism (OA+PCO; group 3) were similar to the classical PCOS groups contrary to the expectations."

Basic

• Peroxisome Proliferator-Activated Receptors-Alpha and Gamma Synergism Modulate the Gut-Adipose Tissue Axis and Mitigate Obesity.
• Obesity Triggers Tumoral Senescence and Renders Poorly Immunogenic Malignancies Amenable to Senolysis.
• Knockout of TSC2 in Nav1.8+ Neurons Predisposes to the Onset of Normal Weight Obesity.
• A Novel Rat Model of Sarcopenic Obesity Based on Aging and High-Fat Diet Consumption.
• Fibroblast Growth Factor 6 Promotes Adipocyte Progenitor Cell Proliferation for Adipose Tissue Homeostasis.
• Depot-Dependent Impact of Time-Restricted Feeding on Adipose Tissue Metabolism in High Fat Diet-Induced Obese Male Mice.

Scientific Rigor & Scholarly Dialogue

• PubPeer Comment On: Cardiometabolic Health Improvements upon Dietary Intervention are Driven by Tissue-Specific Insulin Resistance Phenotype: A Precision Nutrition Trial.
• Evidence for the Carbohydrate-Insulin Model in a Reanalysis of the DIETFITS Trial.
• FTC Asks for RCTs, Not Vague Health Claims.
• Caution Against Rejecting All Dietary Supplements for LDL Cholesterol Reduction.

Clinical

• Pre–post Intervention Exploring Cognitive Function and Relationships with Weight Loss, Intervention Adherence and Dropout.
• RCT: Gender-Specific Effects of Capsiate Supplementation on Body Weight and Bone Mineral Density.
• RCT: Nut-Enriched Energy Restricted Diet Has Potential to Decrease Hunger in Women at Cardiometabolic Risk.
• Early- or Adult-Onset Obesity Has a Similar Cardiometabolic Profile and Weight Loss Response to Clinical Treatment in Adulthood.
• An Examination of Whether Diabetes Control and Treatments are Associated with Change in Frailty Index Across 8 Years: An Ancillary Exploratory Study from the Action for Health in Diabetes (Look AHEAD) Trial.
• The Lived Experience of Patients with Obesity at a Metropolitan Public Health Setting.

Children and Adolescents

• Secular Trend of Self-Concept in the Context of Childhood Obesity.
• Systematic Review: Policy, System, and Environmental Interventions Addressing Obesity and Diet-Related Outcomes in Early Childhood Education Settings.
• Scoping Review: Risk Factors, Cutoff Points, and Definition of Metabolically Healthy/Unhealthy Obesity in Children and Adolescents.
• A Preconception Lifestyle Intervention in Women with Obesity and Cardiovascular Health in Their Children.
• Systematic Review: The Effects of Food Environment on Obesity in Children.
• Nutrient Patterns in Relation to Metabolic Health Status in Adolescents with Overweight or Obesity.
• Did the Increase in Sitting Time Due to COVID-19 Lead to Obesity in Adolescents?

Surgery

• Thromboembolic Complications After Bariatric Surgery: Is the High Risk Real?
• Telomere Length Dynamics Measured by Flow-FISH in Patients with Obesity Undergoing Bariatric Surgery.

Drugs

• The Effect of Xuezhikang Capsule on Gene Expression Profile in Brown Adipose Tissue of Obese Spontaneously Hypertensive Rats.
• Effect of Glucagon-Like Peptide-1 Receptor Agonist on Insulin Secretion Index and Serum Wnt5a Protein in Patients with New-Onset Type 2 Diabetes Mellitus.
• RCT: Efficacy and Safety of Sitagliptin Treatment in Older Adults with Moderately Controlled Type 2 Diabetes.

Food & Diet

• Association between Coffee Consumption, Caffeine Intake, and Metabolic Syndrome Severity in Patients with Self-Reported Rheumatoid Arthritis: National Health and Nutrition Examination Survey 2003–2018.
• Dietary Energy Density, Metabolic Parameters, and Blood Pressure in a Sample of Adults with Obesity.
• Distinct Effects of α-Linolenic Acid and Docosahexaenoic Acid on the Expression of Genes Related to Cholesterol Metabolism and the Response to Infection in THP-1 Monocytes and Immune Cells of Humans with Obesity.
• Mechanisms Mediating the Impact of Maternal Obesity on Offspring Hypothalamic Development and Later Function.
• Effect of Diets Varying in Iron and Saturated Fat on the Gut Microbiota and Intestinal Inflammation: A Crossover Feeding Study Among Older Females with Obesity.
• Ultra-Processed Food Consumption and the Incidence of Obesity in Two Cohorts of Latin-American Young Children.
• Differences in the Gut Microbiota of Women According to Ultra-Processed Food Consumption.

Caloric and Dietary Restriction

• Diurnal Transcriptome Landscape of a Multi-Tissue Response to Time-Restricted Feeding in Mammals.
• RCT: Effects of the Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin on Substrate Metabolism in Prediabetic Insulin Resistant Individuals
• Susceptibility of Human Plasma N-Glycome to Low-Calorie and Different Weight-Maintenance Diets.

Exercise & Physical Activity

• Editorial: Black Box Warning: When Exercise Is Not Medicine.
• Scoping Review: Public Health Guidelines for Physical Activity During Pregnancy from around the World.
• Twelve Weeks of a Diet and Exercise Intervention Alters the Acute Bone Response to Exercise in Adolescent Females with Overweight/Obesity.
• RCT: Moderate-Vigorous Physical Activity Attenuates Premature Senescence of Immune Cells in Sedentary Adults with Obesity.

Economics & Sociology

• The Message Matters: Advertisement Framing and College Women’s Beliefs Toward Exercise.
• Re-Examining the Reversal Hypothesis: A Nationwide Population-Based Study of the Association between Socioeconomic Status, and NCDs and Risk Factors in China.

Epidemiology

• Thesis: The Association between Metabolically Healthy Obesity and Coronary Heart Disease Among Regards Study Participants.
• Incidence of Obesity Across Adulthood in the United States, 2001–2017—a National Prospective Analysis.
• Explaining Obesity Disparities by Urbanicity, 2006 to 2016: A Decomposition Analysis.
• Prevalence and Severity of Chronic Conditions Among Adolescents with Obesity.
• Fatty Acid Transfer from Blood to Milk Is Disrupted in Mothers with Low Milk Production, Obesity, and Inflammation.

Psychology & Neuroscience

• Review: Binge Eating, Overeating and Food Addiction: Approaches for Examining Food Overconsumption in Laboratory Rodents.
• Prenatal Cafeteria Diet Primes Anxiety-Like Behavior Associated to Defects in Volume and Diffusion in the Fimbria-Fornix of Mice Offspring.

Equity and Disparities

• Neighborhood Walkability, Historical Redlining, and Childhood Obesity in Denver, Colorado.
• Preprint: Transportation Noise Exposure, Insulin Resistance and Diabetes: The Role of Sleep and Neighborhood Socioeconomic Status in San Diego County.

Stigma

• Do These Jeans Make Me Feel Fat? Exploring Subjective Fatness, Its Workplace Outcomes, and Rethinking the Role of Subjectivity in the Stigmatization Process.
• The Concept of Healthy Behaviours in Obesity May Have Unintended Consequences.

Policy Related

• Review: Environmental Sustainability in National Food-Based Dietary Guidelines: A Global Review.
• MyPlate and Urban Low-Income Asian Americans in the United States: A Study to Improve Nutrition Education.
• Diet Quality and Nutrition Behavior of Federal Nutrition Education Program Participants Before and During the COVID-19 Pandemic.
• Scoping Review: Measuring Adherence to Sustainable Healthy Diets.
• The Health and Economic Impact of Using a Sugar Sweetened Beverage Tax to Fund Fruit and Vegetable Subsidies in New York City: A Modeling Study.
• Is the Effect of Menu Energy Labelling on Consumer Behaviour Equitable? A Pooled Analysis of Twelve RCTs.
• The Earned Income Tax Credit and Food Insecurity.

Intergenerational Effects

• National, Longitudinal NASCITA Birth Cohort Study: Prevalence of Overweight at 12 Months of Age in Children Born Healthy.
• Intergenerational Pathways between Parental Experiences of Adverse Childhood Experiences (ACEs) and Child Weight: Implications for Intervention.
• Maternal Obesity Damages the Median Eminence Blood-Brain Barrier Structure and Function in the Progeny: The Beneficial Impact of Cross-Fostering by Lean Mothers [in Mice].

Ecology, Evolution, & Energetics

• Review: Photoperiodic Remodeling of Adiposity and Energy Metabolism in Non-Human Mammals.
• Individual Response in Body Mass and Basal Metabolism to the Risks of Predation and Starvation.

Methods

• Reliability and Validity of Assigning Ultraprocessed Food Categories to 24-H Dietary Recall Data.
• Review: Assessment of Human Milk in the Era of Precision Health.
• Overview: 2022 CDC Extended BMI-For-Age Growth Charts for Children and Adolescents with Severe Obesity.
• Report: Evaluation of Alternative BMI Metrics to Monitor Weight Status in Children and Adolescents with Extremely High BMI Using CDC BMI-For-Age Growth Charts. (pdf)

Commentary

• 7 Exercise Myths Debunked.
• How Fats, Sweets Change Your Brain.
• Development of an Approach for Identifying Overnutrition Among Older Adults in Community Health Care Settings: - an Opinion Paper.
• Scientists Raise Alarm About Threats to the Human Microbiome in New Documentary 'The Invisible Extinction'.
• Time-Restricted Eating Reshapes Gene Expression.
• Mechanisms in Aging Process Illuminated by Light-Powered Mitochondria.
• Protein: Magic Ingredient for Intermittent Fasting?
• Telehealth Cognitive Behavioral Therapy Improves HbA1c, Type 2 Diabetes Distress.

General

• Evolution: How (Some) Mammals Lost Their Hair.
• Perceived Status Threat and Health Among White Americans: A Scoping Review.
• How Might Climate Change Affect Adaptive Responses of Polar Arthropods?
• (Not) Far from Home: No Sex Bias in Dispersal, but Limited Genetic Patch Size, in an Endangered Species, the Spotted Turtle (Clemmys guttata).
• Do You Think That the Home Delivery Is Good for Retailing?
• Distributions of Baseline Categorical Variables Were Different from the Expected Distributions in RCTs with Integrity Concerns. (pdf)
• RCT: Does Receiving a SARS-CoV-2 Antibody Test Result Change COVID-19 Protective Behaviors? Testing Risk Compensation in Undergraduate Students.
• Over-Optimism in Unsupervised Microbiome Analysis: Insights from Network Learning and Clustering.
• Mistakes Happen in Research Papers. But Corrections Often Don't.

Announcements

• IU Bloomington School of Public Health Seeks Chair of the Department of Environmental and Occupational Health.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Indiana University School of Public Health-Bloomington Is Recruiting for Tenure-Track Faculty in Every Department!