Obesity and Energetics Offerings

Featured

• RCT: Morning Exercise Reduces Abdominal Fat and Blood Pressure in Women; Evening Exercise Increases Muscular Performance in Women and Lowers Blood Pressure in Men.
• Pharmacological Regulation of Melanocortin-3 And-4 Receptors by Melanocortin-2 Receptor Accessory Protein 1 or 2.
• "Contrary to our hypothesis, our results documented significant associations between adherence to the EAT-Lancet diet and incidence of cancer only in some subgroups, and no association with CVD."

Headline vs Study

• Headline: Strawberries May Fend Off Alzheimer's.
• Study: Associations between estimated pelargonidin intake (a compound found in strawberries) from food frequency questionnaires and neuropathological markers of Alzheimer's. "The study was an observational study and does not prove a direct causal relationship."

Contrary or Null Findings

• Systematic Review: "results from 6/6 RCTs favoured control with respect to body weight and composition, although most of these effects were small. This was contrary to cohort study results suggesting small benefits of walnut consumption on body weight."
• "Aerobic scope (AS) showed the same pattern as SMR, differing across habitats, but contrary to expectations, was lower in pelagic perch."
• "there is no evidence for proposed effects [of gluten] on driving appetite by the brain, nor on energy expenditure and weight gain. "
• RCT: "Men receiving radical RT and ADT gained weight and had increases in waist circumference over time, which metformin did not significantly mitigate."
• RCT: Null Effects of Inulin Supplementation on Body Composition and Metabolic Outcomes in Children with Obesity.
• Systematic Review: Low- and No-Calorie Sweetened Beverages "were not associated with cardiometabolic harm in analyses that model the exposure as change or substitutions."
• RCT: "timing of starting a weight loss attempt [does not appear to affect] ...weight change and trajectory after 12 months in adults newly diagnosed with moderate-severe OSA and treated at home with overnight CPAP."
• Meta-Analysis: "Based on low certainty evidence, early feeding may have little to no effect on necrotizing enterocolitis, feed intolerance, and days to regain birth weight."

Basic

• Octopamine Mediates Sugar Relief from a Chronic-Stress-Induced Depression-Like State in Drosophila.
• Codon-Optimized FAM132b Gene Therapy Prevents Dietary Obesity by Blockading Adrenergic Response and Insulin Action.
• The AAV-PCSK9 Murine Model of Atherosclerosis and Metabolic Dysfunction.
• T-Bet+ B Cells Accumulate in Adipose Tissue and Exacerbate Metabolic Disorder During Obesity.
• The Ameliorating Effects of Metformin on Disarrangement Ongoing in Gastrocnemius Muscle of Sarcopenic and Obese Sarcopenic Mice.
• Hepatokine Fetuin B Expression Is Regulated by Leptin-STAT3 Signalling and Associated with Leptin in Obesity.

Scientific Rigor & Scholarly Dialogue

• Letter: Troubling Assumptions Behind GBD 2019 on the Health Risks of Red Meat.
• Video: Debate - Should We Eat More Processed Foods?

Clinical

• Weight Loss Outcomes Achieved by Adults Accessing an Online Programme Offered as Part of Public Health England’s ‘Better Health’ Campaign.
• Association of Changes in Histologic Severity of Nonalcoholic Steatohepatitis and Changes in Patient-Reported Quality of Life.
• The Promise of New Anti-Obesity Therapies Arising from Knowledge of Genetic Obesity Traits.

Children and Adolescents

• The Association between Weight Loss and Long Term Development in Quality-Of-Life Among Children Living with Obesity: A Pragmatic Descriptive Intervention Study.
• Does Increasing Parental Knowledge of Healthy Behaviors Lead to Lifestyle Changes for Children with Overweight or Obesity? A Prospective Study. (pdf)
• Identifying Modifiable Obesogenic Behaviors Among Latino Adolescents in Primary Pediatric Care.
• Thesis: Digitally-Delivered Healthcare for Children and Adolescents with Obesity.
• Systematic Review: Healthy and Sustainable Dietary Patterns in Children and Adolescents.
• A Longitudinal Effectiveness Study of a Child Obesity Electronic Health Record Tool.

Surgery

• Perception of Bariatric Surgery and Endoscopic Bariatric Therapies Among Primary Care Physicians.
• Behavioral Interventions to Attenuate Driven Overeating and Weight Regain After Bariatric Surgery.
• Innovative Bariatric Procedures and Ethics in Bariatric Surgery: The IFSO Position Statement.
• RCT: Endoscopic Sleeve Gastroplasty for Treatment of Class 1 and 2 Obesity (MERIT).

Drugs

• Discovery of MK-1462: GLP-1 and Glucagon Receptor Dual Agonist for the Treatment of Obesity and Diabetes.
• In Silico and in Vitro Analysis of PPAR – α / γ Dual Agonists: Comparative Evaluation of Potential Phytochemicals with Anti-Obesity Drug Orlistat.
• Effect of HIV and Antiretroviral Therapy Use on Body Weight Changes in a Cohort of U.S. Veterans Living with and Without HIV.

Food & Diet

• RCT: Effect of a Peanut-Enriched Weight Loss Diet Compared to a Low-Fat Weight Loss Diet on Body Weight, Blood Pressure, and Glycemic Control.
• Cinnamon Extract Improves Abnormalities in Glucose Tolerance by Decreasing Acyl-CoA Synthetase Long-Chain Family 1 Expression in Adipocytes.
• Dose-Response Relationship between Dietary Inflammatory Index and Diabetic Kidney Disease in US Adults.

Caloric and Dietary Restriction

• RCT: Effectiveness of Early Time-Restricted Eating for Weight Loss, Fat Loss and Cardiometabolic Health in Adults with Obesity.
• Life-Long Dietary Restrictions Have Negligible or Damaging Effects on Late-Life Cognitive Performance: A Key Role for Genetics in Outcomes.
• Unexpected Role for IGF-1 in Starvation: Maintenance of Blood Glucose.
• RCT: Effect of 5:2 Fasting Diet on Liver Fat Content in Patients with Type 2 Diabetes with Nonalcoholic Fatty Liver Disease.

Exercise & Physical Activity

• Systematic Review: Golf and Physical Health.
• Mathematical Modeling Reveals Differential Dynamics of Insulin Action Models on Glycerol and Glucose in Adolescent Girls with Obesity.
• A Latent Transition Analysis of Physical Activity and Screen-Based Sedentary Behavior from Adolescence to Young Adulthood.

Economics & Sociology

• Non-Farm Employment Promotes Nutritious Diet Without Increasing Carbon Footprint: Evidence from Rural China.
• RCT: The Impact of Increasing the Availability of Lower Energy Foods for Home Delivery and Socioeconomic Position.

Epidemiology

• The Timing of Adiposity and Changes in the Life Course on the Risk of Cancer.
• Obesity and Lifestyle Habits Among Kidney Transplant Recipients.
• The Weight of Childhood Adversity: Evidence That Childhood Adversity Moderates the Impact of Genetic Risk on Waist Circumference in Adulthood.
• Smoothened Percentiles for Height, Weight and BMI of Urban School Going Adolescents Aged 11-17 Years in National Capital Territory Region of Delhi, India.
• Exposure to Outdoor and Indoor Air Pollution and Risk of Overweight and Obesity Across Different Life Periods: A Review.
• Systematic Review: Body Composition and Prostate Cancer Risk.
• Obesity in Young Sudden Cardiac Death: Rates, Clinical Features, and Insights Into People with BMI >50kg/m2.

Psychology & Neuroscience

• Perceived Intrinsic, Social, and Environmental Barriers for Weight Management in Older Hispanic/Latino Adults with Obesity.
• Barriers and Facilitators of Participation in Weight Loss Intervention for Patients with Suboptimal Weight Loss After Bariatric Surgery.
• RCT: A Feasibility Study of Food-Related Computerised Attention Training Versus Mindfulness Training for Adults with Overweight or Obesity.
• Impulsivity Is Longitudinally Associated with Healthy and Unhealthy Dietary Patterns in Individuals with Overweight or Obesity and Metabolic Syndrome Within the Framework of the PREDIMED-Plus Trial.

Equity and Disparities

• Impact of Trends and Gender Disparity in Obesity on Future Type 2 Diabetes in Turkey: A Mathematical Modelling Analysis.
• Regional Disparities in Dual Burden of Malnutrition Among Rural Men in India: Evidence from National Family Health Survey.
• Translating the Recommended Multicomponent Intervention for Childhood Overweight and Obesity Into Practice: Implementation Challenges.
• Mitigating Breast Cancer Disparities by Addressing the Obesity Epidemic.

Stigma

• Weight Stigma of Nutrition and Dietetics Students Towards People with Obesity.
• Comparison of Perceived Weight Discrimination between Polish and German Patients Underwent Bariatric Surgery or Endoscopic Method Versus Conservative Treatment for Morbid Obesity: An International Multicenter Study.

Policy Related

• From Healthy Food Environments to Healthy Wellbeing Environments: Policy Insights from a Focused Ethnography with Low-Income Parents’ in England.
• Reshaping Food Policy and Governance to Incentivize and Empower Disadvantaged Groups for Improving Nutrition.
• Strengthening US Food Policies and Programs to Promote Equity in Nutrition Security: A Policy Statement from the American Heart Association.

Intergenerational Effects

• Maternal and Neonatal Outcome of Women Before Vs. After Bariatric Surgery: A Single Tertiary Center Experience.
• Association of Prepregnancy Physical Activity with Obesity in Offspring: The Japan Environment and Children's Study.
• Systematic Review: General Parenting Intervention Impacts on Child Weight as a Secondary Outcome.
• Prospective Relations of Maternal Reward-Related Eating, Pregnancy Ultra-Processed Food Intake and Weight Indicators, and Feeding Mode with Infant Appetitive Traits.

Ecology, Evolution, & Energetics

• The Comparative Energetics of the Carnivorans and Pangolins.
• Overwintering in North American Domesticated Honeybees (Apis mellifera) Causes Mitochondrial Reprogramming While Enhancing Cellular Immunity.

Methods

• Biological Age for Chronic Kidney Disease Patients Using Index Model.
• Body Weight and Obstructive Sleep Apnea: A Mathematical Relationship between BMI and Apnea-Hypopnea Index in Veterans.
• Accuracy of Body Composition Measurement Techniques Across the Age Span.
• Towards Systems Models for Obesity Prevention: A Big Role for Big Data.
• Novel Approaches to Evaluate Dietary Quality: Combining Methods to Enhance Measurement for Dietary Surveillance and Interventions.

Mathematical and Quantitative

• Dietary Alterations in Impaired Mitochondrial Dynamics Due to Neurodegeneration.
• Can Math Help Us Understand the Gut System of People with Obesity?

Commentary

• When Modern Science Meets Ancient Traditions.
• Avoiding Injury Part II: Grip Strength.
• Health Benefits and Risks of Chocolate.
• Childhood Obesity, Part 2: We Could Fix It… Any Time We Wanted.
• Fresh, Canned, or Frozen: Which Is Better?
• Does Eating High-Fat Dairy Cause Heart Disease or Obesity? Has the Science Changed in the Last Decade?
• Semaglutide SELECT Study: No News Is News.
• When Scientific Paradigms Collide - What If Overeating Doesn’t Make You Fat?

General

• Research Culture: Highlighting the Positive Aspects of Being a PhD Student.
• Dogs and the Good Life: A Cross-Sectional Study of the Association between the Dog-Owner Relationship and Owner Mental Wellbeing.
• Clinical Features Distinguishing Diabetic Retinopathy Severity Using Artificial Intelligence.
• NIH Launches Experimental Science Rigor Initiative.
• Constructive and Obsessive Criticism in Science.
• Rigor and Transparency Index: Large-Scale Analysis of Scientific Reporting Quality.
• Comparative Genome Anatomy Reveals Evolutionary Insights Into a Unique Amphitriploid Fish.
• Retractions are Increasing, but Not Enough.

Announcements

• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency And/ or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Civic Champs from Bloomington, IN Was Named the Winner of 2022 HungerTech Challenge.
• Webinar: Spreading Effective Interventions to Support Healthy Child Growth: CDC’s Data Modernization and Implementation Science Efforts August 18, 2022, 2:00 P.m. ET.
• IU's Dr. Nasser Paydar Confirmed as Assistant Secretary for Postsecondary Education.

Featured

• No Evidence for Nudging After Adjusting for Publication Bias.
• Human Total, Basal and Activity Energy Expenditures are Independent of Ambient Environmental Temperature.
• The Evolution of Dog Diet and Foraging: Insights from Archaeological Canids in Siberia.
• Hepatic TORC2 Signaling Facilitates Acute Glucagon-Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice.

Headline vs Study

• Headline: Transport for London Junk Food Ad Restrictions ‘Have Led to Fewer Obesity Cases’.
• Press Release: Junk Food Advertising Restrictions Prevent Almost 100,000 Obesity Cases.
• Study: Micro Simulation Health Economic Modeling Study of London Obesity Rates.
• Critique: Obesity in London? 100,000 Cases Prevented!

Contrary or Null Findings

• RCT: "No significant intervention group differences were observed...[in]...multiple-component mindfulness intervention for Chinese adolescents living with overweight."
• RCT: Three Weeks of Time-Restricted Eating Improves Glucose Homeostasis in Adults with Type 2 Diabetes but Does Not Improve Insulin Sensitivity.
• RCT: Dihydrocapsiate Does Not Increase Energy Expenditure nor Fat Oxidation During Aerobic Exercise in Men with Overweight/obesity. (PDF)
• RCT: No Significant Effects of Treatment Assignment in Cardiometabolic Effects of Early Vs. Delayed Time-Restricted Eating Plus Caloric Restriction in Adults with Overweight and Obesity.
• RCT: Vitamin D3 Supplementation Did Not Result in a Significantly Lower Risk of Fractures Than Placebo Among Generally Healthy Midlife and Older Adults Who Were Not Selected for Vitamin D Deficiency, Low Bone Mass, or Osteoporosis.
• "Contrary to studies in residential areas and schools, nutrition environments were not related to nutrition practices in ECEs."
• "No school-level factor was statistically associated with the sustainment of overall weekly PA or energisers scheduled."
• RCT: "Intuitive eating alone or in combination with nutritional guidelines did not alter the general domains of eating behaviors, weight, and BMI in individuals with obesity."

Basic

• Cooperative Action of Gut-Microbiota-Accessible Carbohydrates Improves Host Metabolic Function.
• Early Life Dietary Exposures Mediate Persistent Shifts in the Gut Microbiome and Visceral Fat Metabolism.
• Disruption of Adipocyte HIF-1α Improves Atherosclerosis Through the Inhibition of Ceramide Generation.

Scientific Rigor & Scholarly Dialogue

• Competing Paradigms of Obesity Pathogenesis: Energy Balance Versus Carbohydrate-Insulin Models.
• A Brief History and Future of the Traffic Light Diet.
• Support Europe’s Bold Vision for Responsible Research Assessment.
• Article: Perspective: Obesity—an Unexplained Epidemic.
• Letter: Could Increasing Inequalities in Energy Intake Partly Explain the Increasing Prevalence of Obesity Despite a Leveling Mean Intake?

Clinical

• RCT: Effects of Inulin Supplementation on Body Composition and Metabolic Outcomes in Children with Obesity.
• Obesity Indexes are Positively Correlated with Blood Pressure Variability in Patients with Essential Hypertension.
• Preventing Obesity in Midlife Women: A Recommendation from the Women's Preventive Services Initiative.
• Meta Analysis: Impact of Program Characteristics on Weight Loss in Adult Behavioral Weight Management Interventions.

Children and Adolescents

• “Fat but Fit” Paradox and Cardiometabolic Risk in Children: The Role of Physical Activity.
• Diagnosis Accuracy of Waist-To-Height Ratio to Predict Cardiometabolic Risk in Children with Obesity.
• Green and Blue Spaces and Lung Function in the Generation XXI Cohort: A Life Course Approach.
• Trends in Obesity Prevalence Among Children and Adolescents Aged 2 to 19 Years in the US from 2011 to 2020.

Surgery

• RCT: Weight Loss and β-Cell Responses Following Gastric Banding or Pharmacotherapy in Adults with Impaired Glucose Tolerance or Type 2 Diabetes.
• Review: The Impact of Bariatric and Metabolic Surgery on Cancer Development.
• Altered Glucose Metabolism and Glucose Transporters in Systemic Organs After Bariatric Surgery.
• Meta-Analysis: De Novo Inflammatory Bowel Disease Following Bariatric Surgery.

Drugs

• Meta-Analysis: Metformin and Thyroid Carcinoma Incidence and Prognosis.
• Preclinical Efficacy of INST3399, a Synthetic Novel PKCbeta Inhibitor, for the Treatment of Obesity and Fatty Liver Disease.
• Obesity Treatment - Overview of Pharmacological and Surgical Methods.

Food & Diet

• About EAT-Lancet 2.0.
• USPSTF Final Research Plan: Food Insecurity.
• Meta-Analysis: Efficacy of the Omega-3 Fatty Acids Supplementation on Inflammatory Biomarkers.
• Food Insecurity, Food Environments, and Disparities in Diet Quality and Obesity in a Nationally Representative Sample of Community-Dwelling Older Americans.
• Identification of Different Lipoprotein Response Types in People Following a Mediterranean Diet Pattern with and Without Whole Eggs.
• Review: A Conceptual Framework for Understanding the Environmental Impacts of Ultra-Processed Foods and Implications for Sustainable Food Systems.

Caloric and Dietary Restriction

• Temporal Dynamics of the Intestinal Microbiome Following Short-Term Dietary Restriction.
• Podcast: Matt Kaeberlein Discusses Healthspan, Longevity, and Rapamycin. 
• Podcast: Why Do We Get Old, and Can Aging Be Reversed?

Exercise & Physical Activity

• Sedentary Behavior and Cardiovascular Disease Risk: An Evolutionary Perspective.
• Career-Best Changes in Body Mass and Physical Fitness Test Performance Among Division 1 College Football Players Encompassing 28 Years at the Same Institution.
• Meta-Analysis: Effects of Physical Exercise on Bone Mineral Density in Older Postmenopausal Women.
• Phosphoproteomics of Three Exercise Modalities Identifies Canonical Signaling and C18ORF25 as an AMPK Substrate Regulating Skeletal Muscle Function.

Economics & Sociology

• Exploring the Relationship between Self-Employment and Women’s Cardiovascular Health.
• The Association between the Presence of Fast-Food Outlets and BMI: The Role of Neighbourhood Socio-Economic Status, Healthy Food Outlets, and Dietary Factors.
• Assessing the Affordability of Nutrient-Adequate Diets.

Epidemiology

• Gender Differences in the Relationship between Food Insecurity and BMI Among Adults in the USA.
• Preprint: Association of Machine Learning-Derived Measures of Body Fat Distribution in >40,000 Individuals with Cardiometabolic Diseases.
• Analysis of Somatic Mutations in 131 Human Brains Reveals Aging-Associated Hypermutability.
• Analysis of Epigenetic Age Acceleration and Healthy Longevity Among Older US Women.

Psychology & Neuroscience

• The Association between Childhood Trauma and Overweight and Obesity in Young Adults: The Mediating Role of Food Addiction.
• Evidence for a Neuromuscular Circuit Involving Hypothalamic Interleukin-6 in the Control of Skeletal Muscle Metabolism.

Equity and Disparities

• Disparities in Sleep Duration Among American Children: Effects of Race and Ethnicity, Income, Age, and Sex.
• A Healthy Plant-Based Diet Was Associated with Slower Cognitive Decline in African American Older Adults: A Biracial Community-Based Cohort.
• Preprint: Decades of Systemic Racial Disparities in Funding Rates at the National Science Foundation.

Stigma

• Anti-Fat Attitudes Among Spanish General Population: Psychometric Properties of the Anti-Fat Attitudes Scale.
• Weight-Based Teasing, Body Dissatisfaction, and Eating Restraint: Multilevel Investigation Among Primary Schoolchildren.
• Video: Weight Stigma in the Media - Panel Discussion.

Policy Related

• Supply Chain Crisis Leads to 60% Increase in Food Waste in Just Six Months.
• Benchmarking the Nutrition-Related Commitments and Practices of Major French Food Companies.
• An 18-Country Analysis of the Effectiveness of Five Front-Of-Pack Nutrition Labels.

Intergenerational Effects

• Intrauterine Malnutrition Disrupts Leptin and Ghrelin Milk Hormones, Programming Rats.
• Evaluation of Subclinical Atherosclerosis and Cardiac Functions in Children of Mothers with Gestational Diabetes and Maternal Obesity.

Ecology, Evolution, & Energetics

• Review: Hindbrain Circuits in the Control of Eating Behaviour and Energy Balance.
• Genome Size Drives Morphological Evolution in Organ-Specific Ways.

Methods

• A Strategy for Accurately and Sensitively Quantifying Free and Esterified Fatty Acids Using Liquid Chromatography Mass Spectrometry.
• How to Avoid Overestimating the Burden of Hypertension in Epidemiological Studies? A New Methodology to Account for Within-Person Variability of Blood Pressure.

Commentary

• Intermittent Fasting and the Ketogenic Diet: Why They are Harmful.
• Vitamin D: The Panacea That Isn’t.
• Childhood Obesity Worsens: Fiddlers, All, as Rome Burns?
• Energy Balance Versus Insulin and Carbs, Again.
• CRISPR-Based Genome Editing for Nutrient Enrichment in Crops: A Promising Approach Toward Global Food Security.
• How Humans Adapted to Digest Lactose — After Thousands of Years of Milk Drinking.
• Diverse Thinking About the Complexity of Obesity.
• Emergency Contraception Caution for Women with Obesity.
• What If the Focus on Calories and Energy Balance Is Simply Wrong?
• When Is Obesity Care Worth It?

General

• Video: What Role Does Google Play in Public Health?
• Invasive Fish: Sperm Hijacking as Success Strategy.
• How Do Fitness Trackers Monitor Your Sleep?
• Climate Change May Be Culprit in Antarctic Fish Disease Outbreak.
• Commentary On: The Fallacy of Science Is Science: The Impact of Conflict of Interest in Vaping Articles.
• Are You Clumsy—or Just Mean? Your Dog May Know the Difference.
• The Impact of Optical Impressions on Dog Feeding Practice.
• "Craft beer showed greater acceptance when consumed to the sound of classic rock."
• A.I. Predicts the Shape of Nearly Every Protein Known to Science.
• Distinguishing Bad Use of Science from Bad Science.

Announcements

• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency And/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• "U.S. News & World Report has released its 2022-2023 ‘Best Hospitals’ rankings that include Indiana University Health Medical Center among the nation’s top adult hospitals for the 25th consecutive year."
• "Registration is now open for the causes of obesity meeting at the Royal Society (London Oct 17-19th 2022). Free to attend. Unlimited online places. In person attendance numbers are limited."

Featured

• An Analysis of the Recent U.S. Dietary Guidelines Process in Light of Its Federal Mandate and a National Academies Report.
• Age and Diet Shape the Genetic Architecture of Body Weight in Diversity Outbred Mice.
• Tirzepatide Once Weekly for the Treatment of Obesity.
• Review: Bioactive Compounds in Mothers Milk Affecting Offspring Outcomes.

Headline vs Study

• Headline: Common Migraine Prescription Could Treat Obesity: Study.
• Press Release: UTSW Researchers Show Effectiveness of Migraine Drug in Weight Loss.
• Study: Delineating a Serotonin 1B Receptor Circuit for Appetite Suppression ... In Mice.

Contrary or Null Findings

• RCT: "No statistically significant differences were observed between low and high avocado allotment groups in liver enzymes, GGT, hsCRP or NAFLD fibrosis score."
• RCT: "The [Small Change Approach] did not prevent weight gain compared with monitoring alone at 2 or 3 years in adults with overweight or obesity".
• "Together, contrary to our hypothesis, heat-killed probiotics did not improve neutrophil function and survival outcome in a murine severe burn injury model."
• "Contrary to affect regulation theory and laboratory data, but consistent with prior ecological momentary assessment data in children and adolescents, pre-meal NA was not linked to subsequent LOC-eating."
• Antibiotic Therapy Does Not Alter Mitochondrial Bioenergetics in Lymphocytes of Patients with Septic Shock – a Prospective Cohort Study.
• RCT: Blood Flow Restriction Therapy for Two Weeks Prior to Anterior Cruciate Ligament Reconstruction Did Not Impact Quadriceps Strength Compared to Standard Therapy.
• No Association between Infant Growth and Adherence to the Dietary Approaches to Stop Hypertension (DASH) Diet in Lactating Women.
• RCT: "...daily consumption of 24 ml concentrated BJ [beetroot juice] did not affect the levels of glycemic measures, blood pressure, and lipid profile."
• RCT: "Findings indicated that the intervention did not produce take-home effects on children's home availability of fruit (p = 0.52) and vegetables (p = 0.67) or parental modelling of fruit (p = 0.26) and vegetable consumption (p = 0.78)..."

Basic

• The Gene Knockout of Angiotensin II Type 1a Receptor Improves High-Fat Diet-Induced Obesity in Rat Via Promoting Adipose Lipolysis.
• Macrophage-Specific Connexin 43 Knockout Protects Mice from Obesity-Induced Inflammation and Metabolic Dysfunction.
• Adipose Tissue Myeloid-Lineage Neuroimmune Cells Express Genes Important for Neural Plasticity and Regulate Adipose Innervation.
• A Signature of Exaggerated Adipose Tissue Dysfunction in Type 2 Diabetes Is Linked to Low Plasma Adiponectin and Increased Transcriptional Activation of Proteasomal Degradation in Muscle.
• Multiomics Reveals Persistence of Obesity-associated Immune Cell Phenotypes in Adipose Tissue During Weight Loss and Weight Regain in Mice.
• Preprint: Plasma Level of ATPase Inhibitory Factor 1 (IF1) Is Associated with Type 2 Diabetes Risk in Humans: A Prospective Cohort Study.

Scientific Rigor & Scholarly Dialogue

• Preprint: Limitations of the Food Compass Nutrient Profiling System.
• Avoiding the Effects of Translocation on the Estimates of the Metabolic Rates Across an Elevational Gradient.

Clinical

• Untargeted Lipidomic Analysis of Plasma from Women with Obesity Submitted to Combined Physical Exercise.
• Do Lifestyle Factors and Quality of Life Differ in People with Metabolically Healthy and Unhealthy Obesity?

Children and Adolescents

• Making Every Bite Count: Best Practices for Introducing Foods During the Complementary Feeding Period.
• The 100 Top-Cited Articles on Childhood Obesity: A Bibliometric Analysis.

Surgery

• T and B Cell Composition and Cytokine Producing Capacity Before and After Bariatric Surgery.
• Changes in the Expression of Meteorin-Like (METRNL), Irisin (FNDC5), and Uncoupling Proteins (UCPs) After Bariatric Surgery.
• De Novo Glycine Synthesis Is Reduced in Adults with Morbid Obesity and Increases Following Bariatric Surgery.
• RCT: Weight Loss and β-Cell Responses Following Gastric Banding or Pharmacotherapy in Adults with Impaired Glucose Tolerance or Type 2 Diabetes.
• Desire to Lose Weight Was Associated with the Adoption of Weight Control Strategies but Not Healthier Lifestyle Behaviours Among Post-Bariatric Surgery Patients: NHANES 2013–2018.

Drugs

• Hypoglycemia Risk with SGLT2 Inhibitors or Glucagon-Like Peptide 1 Receptor Agonist Versus Sulfonylureas Among Medicare Insured Adults with CKD in the United States.
• Melanocortin-4 Receptor Complexity in Energy Homeostasis, Obesity and Drug Development Strategies.
• Dysosmobacter welbionis Is a Newly Isolated Human Commensal Bacterium Preventing Diet-Induced Obesity and Metabolic Disorders in Mice.
• Meta-Analysis: Effect of Glucagon-Like Peptide-1 Receptor Agonists on Body Weight in Adults with Obesity Without Diabetes Mellitus.
• RCT: Semaglutide Once a Week in Adults with Overweight or Obesity, with or Without Type 2 Diabetes in an East Asian Population (STEP 6).

Food & Diet

• Body Weight Index Indicates the Responses of the Fecal Microbiota, Metabolome and Proteome to Beef/Chicken-Based Diet Alterations in Chinese Volunteers.
• The Relationship between Dietary Phytochemical Index and Resting Metabolic Rate Mediated by Inflammatory Factors in Women with Overweight and Obesity: A Cross-Sectional Study.
• RCT: Apnoea Occurring in Females Who are Overweight After Menopause.

Caloric and Dietary Restriction

• RCT: Dietary Protein Restriction Improves Metabolic Dysfunction in Patients with Metabolic Syndrome.
• Modestly Increased Incidence of Ketosis in Caloric Restriction Does Not Significantly Alter the Effects of Caloric Restriction.

Exercise & Physical Activity

• School and Non-School Day Screen Time Profiles and Their Differences in Health and Educational Indicators in Adolescents.
• Genome-Wide Association Study of Liking for Several Types of Physical Activity in the UK Biobank and Two Replication Cohorts.

Economics & Sociology

• Changes in Neighborhood Environments and the Increasing Socioeconomic Gap in Child Obesity Risks: Evidence from Singapore.
• The Role of Health-Based Food Choice Motives in Explaining the Relationship between Lower Socioeconomic Position and Higher BMI in UK and US Adults.
• Estimating the Benefits of Obesity Prevention on Productivity: An Australian Perspective.
• Changes in the Local Food-At-Home Environment, Supplemental Nutrition Assistance Program Participation, and Dietary Quality.

Epidemiology

• BMI Moderates the Association between Adverse Childhood Experiences and COPD.
• Obesity Fact Sheet in Korea, 2021: Trends in Obesity Prevalence and Obesity-Related Comorbidity Incidence Stratified by Age from 2009 to 2019.

Psychology & Neuroscience

• More Complex Than You Might Think: Neural Representations of Food Reward Value in Obesity.
• “You are Always at War with Yourself” the Perceptions and Beliefs of People with Obesity Regarding Obesity as a Disease.
• Review: Acts of Appetite: Neural Circuits Governing the Appetitive, Consummatory, and Terminating Phases of Feeding.
• More Complex Than You Might Think: Neural Representations of Food Reward Value in Obesity.
• Objective Physical Activity Accumulation and Brain Volume in Older Adults: An MRI and Whole Brain Volume Study.

Equity and Disparities

• Inequalities in Overweight and Obesity Among Reproductive Age Group Women in India: Evidence from National Family Health Survey (2015–16).
• Income Disparities in Obesity Trends Among U.S. Adults: An Analysis of the 2011–2014 California Health Interview Survey.
• Income-Related Health Inequality in Urban China (1991–2015): The Role of Homeownership and Housing Conditions.

Stigma

• A Public Health Framework for Reducing Stigma: The Example of Weight Stigma.
• Preprint: Mediators of the Association between Childhood BMI and Educational Attainment: Analysis of a UK Prospective Cohort Study.

Policy Related

• The Relationship between Volume of Newspaper Coverage and Policy Action for Nutrition Issues in Australia: A Content Analysis.
• Integrating Nutrition and Food Safety in Food Systems Policy and Programming.
• Intergovernmental Policy Opportunities for Childhood Obesity Prevention in Australia.

Intergenerational Effects

• In-Utero Co-Exposure to Toxic Metals and Micronutrients on Childhood Risk of Overweight or Obesity: New Insight on Micronutrients Counteracting Toxic Metals.
• Associations between Family Functioning During Early to Mid-Childhood and Weight Status in Childhood and Adolescence.

Ecology, Evolution, & Energetics

• Parents Exposed to Warming Produce Offspring Lower in Weight and Condition.
• Genomic Insights Into the Secondary Aquatic Transition of Penguins.
• Diet and Ontogeny Drastically Alter the Larval Microbiome of the Invertebrate Model Galleria mellonella.
• Circulating and Skeletal Muscle MicroRNA Profiles are More Sensitive to Sustained Aerobic Exercise Than Energy Balance in Males.

Methods

• Systematic Review: The Use of Mobile-Based Ecological Momentary Assessment (mEMA) Methodology to Assess Dietary Intake, Food Consumption Behaviours and Context in Young People.
• Dietary Assessment -- Pattern Recognition Rather Than Recall.
• Comparison of Weight Loss Data Collected by Research Technicians Versus Electronic Medical Records: The PROPEL Trial.
• Next Generation Smartwatches to Estimate Whole Body Composition Using Bioimpedance Analysis: Accuracy and Precision in a Diverse Multiethnic Sample.

Mathematical and Quantitative

• Predictive Equations for Energy Expenditure in Adult Humans: From Resting to Free-Living Conditions.
• Obesity and Labour Market Outcomes in Italy: A Dynamic Panel Data Evidence with Correlated Random Effects.
• The Health, Cost and Equity Impacts of Restrictions on the Advertisement of High Fat, Salt and Sugar Products Across the Transport for London Network: A Health Economic Modelling Study.

Commentary

• Genetic Effects: Accounting for Diet and Age.
• Why Don’t Most Foods Cause Allergies?
• Improving Health Through Food Engineering.
• As Diabetes During Pregnancy Grows More Common, Experts Point to a Need for Preventive Care.
• What are the Health Benefits of Watermelon?
• Dietary Assessment: Do We Really Know What People are Eating?
• Is Air Conditioning Causing Obesity?
• Overly Restrictive Salt Intake May Worsen Outcomes for Common Form of Heart Failure.

General

• Remote Video Analysis of an Unusual Fish Life-History Combination: Nest-Building, Paternal Care, and Protogyny in a Seabream.
• Dietary Bacillus licheniformis Improves the Effect of Astragalus membranaceus Extract on Blood Glucose by Regulating Antioxidation Activity and Intestinal Microbiota in InR[E19]/TM2 Drosophila melanogaster.
• Contrary to Popular Belief, Woodpeckers Don’t Protect Their Brains When Headbanging Trees.
• Fact-Value Framework for Adjudicating Public Health Policy Debates.
• A Neuroscience Image Sleuth Finds Signs of Fabrication in Scores of Alzheimer’s Articles, Threatening a Reigning Theory of the Disease.
• Prolonged Administration of Melatonin Ameliorates Liver Phenotypes in Cholestatic Murine Model.
• What Can We Learn from Selfish Loci That Break Mendel’s Law?
• Food Waste Is a Complex Problem That Requires Creative Solutions.
• Food Expiration Dates Don’t Have Much Science Behind Them.

Announcements

• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition or Aging Research Domains.
• Nine IU Faculty Members Named Fulbright US Scholar Award Winners for 2022-23 .
• Webinar: Spreading Effective Interventions to Support Healthy Child Growth: CDC’s Data Modernization and Implementation Science Efforts.

Featured

• Hangry in the Field: An Experience Sampling Study on the Impact [Association] of Hunger on Anger, Irritability, and Affect.
• Food-Seeking Behavior Is Triggered by Skin Ultraviolet Exposure in Males.
• The Impact of Different Dark Chocolate Dietary Patterns on Synaptic Potency and Plasticity in the Hippocampal CA1 Area of the Rats Under Chronic Isolation Stress.
• Higher Than Predicted Resting Energy Expenditure and Lower Physical Activity in Healthy Underweight Chinese Adults.

Headline vs Study

• Headline: The Largest Study Ever on Avocados Has Some Good News for Your High Cholesterol.
• Press Release: Daily Avocados Improve Diet Quality, Help Lower Cholesterol Levels.
• Study: "The primary outcome, change in visceral adipose tissue volume ... was not significantly different" though "modest but nominally significant reductions in total and low-density lipoprotein cholesterol [secondary outcomes] were observed in the Avocado Supplemented compared with the Habitual Diet Group."

Contrary or Null Findings

• RCT: "...contrary to expectations, across all motivational levels (low and high autonomous), the challenge-focused intervention resulted in a greater increase in total daily PA (primary outcome)..."
• RCT: "Acute dietary nitrate supplementation does not change venous volume and compliance in healthy young adults."
• Meta-Analysis: No Compelling Evidence for the Effects of Thiamine Supplementation on Patients with Heart Failure.
• "There was no evidence found that zBMI was associated with school readiness."
• Meta-Analysis: "The pooled effect sizes suggested ... [no] significant effect of androstenedione supplementation on ...body weight … [or] BMI…"
• "We provide novel information on seasonal changes in foraging of humpback whales and suggest that these animals, contrary to nearly all other animals that seasonally fast, exhibit high feeding rates soon after exiting the fasting period."
• Modestly Increased Incidence of Ketosis in Caloric Restriction Does Not Significantly Alter Effects of Caloric Restriction.
• Rapamycin Did Not Prevent the Excessive Exercise-Induced Hepatic Fat Accumulation [in Mice].

Basic

• Retinoic Acid Promotes Tissue Vitamin a Status and Modulates Adipose Tissue Metabolism of Neonatal Rats Exposed to Maternal High-Fat Diet-Induced Obesity.
• Adipocyte Lysoplasmalogenase TMEM86A Regulates Plasmalogen Homeostasis and Protein Kinase A-Dependent Energy Metabolism.
• A Cardiac Amino-Terminal GRK2 Peptide Inhibits Maladaptive Adipocyte Hypertrophy and Insulin Resistance During Diet-Induced Obesity.
• BAF60a Deficiency in Macrophage Promotes Diet-Induced Obesity and Metabolic Inflammation.
• Sex-Specific Changes in Metabolism During the Transition from Chow to High-Fat Diet Feeding are Abolished in Response to Dieting in C57BL/6J Mice.
• Fecal Microbiota Transplantation During Lactation Programs the Metabolism of Adult Wistar Rats in a Sex-Specific Way.
• The Effect of Low Doses of Radon on Ghrelin and Glucose Levels in Rats with Multiple Low-Dose Streptozotoccin-Induced Type 2 Diabetes Mellitus.
• Overexpressing Hydroxycarboxylic Acid Receptor 1 in Mouse Brown Adipose Tissue Restores Glucose Tolerance and Insulin Sensitivity in Diet-Induced Obese Mice.

Scientific Rigor & Scholarly Dialogue

• Enhancing the Trustworthiness of the Endocrine Society’s Clinical Practice Guidelines.
• Poor Reporting Quality in Basic Nutrition Research: Recent Folate Research in Mouse Models.
• Advancing Nutritional Epidemiology by Linking Datasets and Addressing Data Quality.

Clinical

• Systematic Review: Clinical Practice Guidelines for the Prevention of Childhood Obesity.
• Preprint: Effectiveness of EHealth Weight Management Interventions in Adults with Overweight and Obesity from Low Socioeconomic Groups.
• Obesity and “Obesity-Related” Cancers: Are There BMI Cut-Points?

Children and Adolescents

• "Shorter sleep duration and later meal timing are associated with adiposity gain in preschoolers."
• Trends in Metabolic Syndrome Among US Youth, from 1999 to 2018.
• The Impact of Adiposity Indices on Lung Function in Children with Respiratory Allergic Diseases.

Surgery

• Review: Bariatric Surgery Practice Patterns Among Pediatric Surgeons in the United States.
• Psycho-Behavioral Factors Related to Weight Regain After Bariatric Surgery.
• Altered Insulin Clearance After Gastric Bypass and Sleeve Gastrectomy in the Fasting and Prandial Conditions.
• Effect of Exercise Training After Bariatric Surgery: A 5-Year Follow-Up Study.
• "These findings suggest that the detrimental impact of prolonged organ ischemic time may be attenuated by donor obesity."

Drugs

• Review: Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity.
• Review: Medicinal Plants for the Treatment of Obesity and Overweight.
• GLP-1RAs for the Treatment of Obesity in Women After Menopause.
• Network Pharmacology Research Indicates That Wu-Mei-Wan Treats Obesity by Inhibiting Th17 Cell Differentiation and Alleviating Metabolic Inflammation.
• Proton Pump Inhibitor Use and Obesity-Associated Cancers in the Women's Health Initiative.
• Synergism between Obesity and HFpEF on Neutrophils Phenotype and Its Regulation by Adipose Tissue-Molecules and SGLT2i Dapagliflozin.

Food & Diet

• RCT: Prunes Preserve Hip Bone Mineral Density in Postmenopausal Women.
• RCT: "This study suggests potential benefits of n–3-PUFA supplementation to lipoprotein profiles in healthy older adults without dyslipidemia..."
• RCT: Cinnamon Infusion Reduces Satiety and Increases Energy Intake.
• Review: The Effect of Prebiotics on Human Iron Absorption.
• Immune Tolerance of Food Is Mediated by Layers of CD4+ T Cell Dysfunction.
• The Potential Mechanisms of Bergamot-Derived Dietary Fiber Alleviating High-Fat Diet-Induced Hyperlipidemia and Obesity in Rats.
• Effects of Red Rice Bran Extract on High-Fat Diet-Induced Obesity and Insulin Resistance in Mice.
• Chlorella Unsaturated Fatty Acids Suppress High-Fat Diet-Induced Obesity in C57/BL6J Mice.
• Unripe Banana Flour (Musa cavendishii) Promotes Increased Hypothalamic Antioxidant Activity, Reduced Caloric Intake, and Abdominal Fat Accumulation in Rats on a High-Fat Diet.

Caloric and Dietary Restriction

• RCT: Effectiveness and Tolerability of a Two-Week Hypocaloric Protein-Rich Diet Prior to Obesity Surgery with Two Different Diet Interventions.
• The Role of GCN2 Kinase in Mediating the Effects of Amino Acids on Longevity and Feeding Behaviour in Drosophila.
• Intermittent Calorie Restriction Alters T Cell Subsets and Metabolic Markers in People with Multiple Sclerosis.

Exercise & Physical Activity

• Mixed-Method Follow Up : Maintenance of Cardiorespiratory Fitness, Body Composition, and a Physically Active Lifestyle After Structured Exercise Interventions in Individuals with Overweight and Obesity.
• Assessment of Metabolic Flexibility by Substrate Oxidation Responses and Blood Lactate in Women Expressing Varying Levels of Aerobic Fitness and Body Fat.
• The Effects of Exercise and Diet on Mental Status, Insulin Signaling Pathway, and Microbiome in Obese Mice.

Economics & Sociology

• Dissertation: Psychosocial Complexities of American Black Women’s Experiences with Weight Loss or Obesity.
• Household Income and Maternal Education in Early Childhood and Risk of Overweight and Obesity in Late Childhood.
• Do We Get Fat Because of Air Pollution? A New Socio-Economic Approach.
• Exploring the Economics of Public Health Intervention Scale-Up.

Epidemiology

• "Our results indicate that the mean weight gain among adults during the COVID-19 pandemic may be small."
• Association of N,N-Diethyl-M-Toluamide (DEET) with Obesity Among Adult Participants.

Psychology & Neuroscience

• "Contrary to affect regulation theory and laboratory data, but consistent with prior ecological momentary assessment data in children and adolescents, pre-meal negative affect was not linked to subsequent loss of control eating."
• Task-Dependent Effective Connectivity of the Reward Network During Food Cue-Reactivity.
• Brain Responses to Food Choices and Decisions Depend on Individual Hedonic Profiles and Eating Habits in Healthy Young Women.

Equity and Disparities

• The Socio-Economic Inequality in BMI.
• Direct and Indirect Determinants of BMI in Both Major Ethnic Groups Experiencing the Nutritional Transition in Cameroon.

Stigma

• Review: The Consequences of a Weight-Centric Approach to Healthcare: A Case for a Paradigm Shift in How Clinicians Address Body Weight.
• Examining Weight Bias Attitudes and Obesity Beliefs Among Undergraduate Students.

Policy Related

• Scoping Review: School-Based Obesity Prevention Programs in Rural Communities.
• Thesis: Association of Media and Messaging on the Impact of the Seattle Sugar-Sweetened Beverage Tax.
• A Proposal to Unify the Definition of the Metabolic Syndrome in Children and Adolescents.
• Supplemental Nutrition Assistance Program (SNAP)-Authorized Retailers Received a Low Score Using the Business Impact Assessment for Obesity and Population-Level Nutrition (BIA-Obesity) Tool.

Intergenerational Effects

• Periconceptional and First Trimester Ultraprocessed Food Intake and Maternal Cardiometabolic Outcomes.
• Maternal Pre-Pregnancy BMI and Offspring Hyperactivity–inattention Trajectories from 3 to 8 Years.
• From Pregnancy to Breastfeeding: Adequate Maternal BMI Is Essential to Prevent a High BMI in Your Children.

Ecology, Evolution, & Energetics

• Avoiding the Effects of Translocation on the Estimates of the Metabolic Rates Across an Elevational Gradient.
• Predictive Simulations to Replicate Human Gait Adaptations and Energetics with Exoskeletons.
• Obligatory Homeothermy of Mesic Habitat-Adapted African Striped Mice, Rhabdomys pumilio, Is Governed by Seasonal Basal Metabolism and Year-Round ‘Thermogenic Readiness’ of Brown Adipose Tissue.

Methods

• Measuring the Reliability of a Frequency Method for Assessing Vegetable Intake Using Photos: A Smart Phone Approach.
• Using Self-Monitoring Technology for Nutritional Counseling and Weight Management.
• Differing Associations with Childhood Outcomes Using Behavioural Patterns Derived from Three Data Reduction Techniques.

Commentary

• How Strong Is the Evidence Base for Carbohydrate Restriction in the Management of T2D?
• Food Texture Trumps Food Processing in the Regulation of Energy Intake.
• Does Excessive Fast-Food Consumption Impair Our Health?
• Study Shows Grocery Shoppers are Coping with Inflation.
• Seeking Value in Obesity Medicine.
• This Diet vs That Diet, and the Winner Is….
• Indicators of Stress Rising in Parallel with Obesity.
• Appetite Control in Obesity.

General

• Methane Much More Sensitive to Global Heating Than Previously Thought, According to Study.
• "..mechanistic insights on a life-threatening mammalian meat allergy brought on by tick bites.."
• A Writer in Pain: As an Unwelcome, Cruel Guest, Pain Infiltrates the Body.
• Can Algae Unlock the Secrets of Photosynthesis?
• Divergent Cis-Regulatory Evolution Underlies the Convergent Loss of Sodium Channel Expression in Electric Fish.
• Longitudinal Analysis: Relationships Among Travel, Social and Occupational Participation, and Life Satisfaction for People with Mobility Disability.
• Thesis: The Effect of Reading Direction and History of Multiple Concussions on the King-Devick Test.
• Wonder of Wonders, Miracle of Miracles: The Unprecedented Speed of COVID-19 Science.

Video & Audio

• Webinar : Virtual Care for Patients with Obesity [July 28th].

Announcements

• New Book: Energy and Evolutionary Conflict: The Metabolic Roots of Cooperation.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency And/or Statistical and Data Analytic Research in the Obesity, Nutrition or Aging Research Domains.