Obesity and Energetics Offerings

Featured

• Perspective: All That Glitters Ain’t Gold: The Myths and Scientific Realities About the Gut Microbiota.
• Protocol: FLEX: Flight Exercise Training Protocol for the Fruit Fly Drosophila.
• Human Energy Expenditure and Thermoregulation During Persistence Hunting in the Namib.

Headline vs Study

• Headline: This Daily Activity Can Slow Neurodegeneration — Here’s How.
• Study: Association (not Necessarily Effect) of Self-Reported Physical Exercise with Structural Brain Changes and Cognitive Decline in Patients with Early Parkinson Disease. No Specific Activity Identified.

Contrary or Null Findings

• Preprint: "There were no significant differences in change over time of total or self-reported PA between the groups" [in] Feasibility and Physical Health Outcomes of a 1-Year Sport-Based Physical Activity Intervention in Rural Middle School Children.
• Meta-Analysis of RCTs: "yacon use in adults does not lead to significant improvements in lipid profiles or glycemic parameters."
• Much Ado About Nothing: Tirzepatide and Medullary Thyroid Cancer Debunked.
• Mild Hyperbaric Oxygen Does Not Attenuate Mitochondrial Decrease Induced by Detraining in Mice.
• News: “We Were Somewhat Surprised by the Fact That Despite Differences in Receptor Activity and Potency, Dulaglutide, Semaglutide, and Tirzepatide Showed a Remarkably Similar Risk of Serious Gastrointestinal Events.”
• Meta-Analysis of RCTs: "In general, KDs [ketogenic diets] can reduce traditional liver enzyme levels (ALT, AST, ALP, and GGT), but they appear to have no significant effect on liver stiffness."
• Meta-Analysis of Mendelian Randomization Studies: "In MR [Mendelian Randomization] analyses, higher BMI, BFP, WC, and WHR were associated with a reduced risk of cognitive impairment, with WHR also inversely related to mild cognitive impairment."

Basic

• NPFFR2 Deletion Improves Hypothalamic Insulin Sensitivity and Metabolic Outcomes in Mice with Diet-Induced Obesity.
• Soy Isoflavones Prevent Bone Quality Loss Induced by High-Fat Diet in Rats Through Epigenetic Modifications.
• JMJD8 Facilitates Hepatic Lipid Deposition and Metabolic Dysfunction.
• Lactiplantibacillus plantarum Attenuates Diet-Induced Obesity and Insulin Resistance Through Gut Microbiota-Driven PPAR/PI3K-Axis Modulation.
• Preprint: Exercise Training Improves Sarcopenic Muscle Function Via Restoration of Mitochondrial Quality Control.
• AQP7 Deficiency Drives Adipose Tissue Remodeling and Disrupts Homeostasis.

Scientific Rigor & Scholarly Dialogue

• Sometimes Numbers for Obesity Get Fuzzy - “At a press event last week, announcing a deal to make obesity medicines more affordable, CMS Administrator Mehmet Oz told us ‘Americans will lose 135 billion pounds by the midterms’ because of this.”.
• Letter: Doubting Doubly Labeled Water.
• Response: Reply to Uzoigwe: DLW Is Safe and Validated.
• Acknowledge the Merits and Limitations of Exercise Quantification Methods to Better Control the Dose-Response Relationship.

Clinical

• RCT: Curcumin Supplementation Increases Butyrogenic Bacteria in the Gut of Obese Individuals Following a Weight-Loss Diet.
• Non-Randomized Controlled Trial: Interprofessional Nutrition and Dysphagia Management for Care-Dependent Older Adults in Day-Care Services.
• RCT: The VEGPREV Study: Effectiveness of Four Plant-Based Diets on Weight Loss, Metabolic Syndrome Components and Appetitive Traits in Individuals with Overweight or Obesity.
• Dynapenic Abdominal Obesity Is Associated with Long-Term Cognitive Trajectories and Mild Cognitive Impairment.
• Plasma Fatty Acids and the Likelihood of Healthy Aging.

Children and Adolescents

• The Stronger Predictive Role of Early Life Exposures Versus Current Lifestyle Behaviors on the Development of Childhood Severe Obesity and Metabolic Dysfunction.
• Long-Term Effect of a Hospital-Based Intervention Program on BMI Trajectories in Danish Children and Adolescents with Overweight and Obesity: A 6-Year Follow-Up.
• Pilot Study: Testing Implementation Strategies for a Family Healthy Weight Program.
• Meta-Analysis: Prevalence of Obesity Among School-Going Children in India.
• RCT: Personal Activity Trackers and Family Engagement in a Pediatric Obesity Intervention.

Surgery

• Diurnal Rhythm in Meal Responses of Hunger and Appetite in Bariatric Surgery Patients One Year After Vertical Sleeve Gastrectomy.
• Variation of Metabolic and Bariatric Surgery Utilization by Neighborhood Socioeconomic Status in Maryland.
• Review: Are Glucagon-Like Peptide 1 Receptor Agonists and Bariatric Surgery the Answer to Childhood Obesity?
• Binge Eating, Food Addiction, and Body Image Dissatisfaction Before and After Metabolic Bariatric Surgery: Weight Loss Occurs, but the Relationship with Food and the Body May Not Improve in the Long Term After Surgery.
• RCT: Liraglutide and Weight Loss Among Suboptimal Responders to Metabolic Bariatric Surgery.

Drugs

• A Hidden Confounder for Microbiome Studies: Medications Used Years Before Sample Collection.
• Meta-Analysis of RCTs: Weight Loss, Obesity Medication, and Risk of Obesity-Associated Cancer.
• People with Lowest Physical Functioning Scores Showed Greatest Improvement After Tirzepatide Treatment.
• News: Merck's Oral PCSK9 Inhibitor Enlicitide Demonstrated Antibody-Like LDL-C Lowering in Adults with HeFH with Safety Profile Similar to Placebo in Phase 3 Trial.

Food & Diet

• The Anti-Inflammatory Effects of Three Different Dietary Supplement Interventions.
• Review: From Soil to Health: Advancing Regenerative Agriculture for Improved Food Quality and Nutrition Security.

Caloric and Dietary Restriction

• Metabolic Biomarkers for Lifespan Extension and Cellular Stress in Saccharomyces cerevisiae During Calorie Restriction and Quercetin Treatment.
• Caloric Restriction Substantially Improves Glucose Regulation in Mice with Hnf1a-Deficient Beta-Cells.

Exercise & Physical Activity

• Ethnography and Ethnohistory Support the Efficiency of Hunting Through Endurance Running in Humans.
• Analysis of RCTs: Effects of Exercise Modalities on Heart Rate Recovery and Its Association with Cardiometabolic Risk in Adolescents with Overweight or Obesity.
• Viewpoint: Personalised Physical Activity Guidelines for Pregnant Women with Overweight and Obesity: A Neglected Priority.
• RCT: Examining the Impact of a Codeveloped Multicomponent Mobile EHealth Lifestyle Intervention on Physical Activity and Its Association with Gestational Weight Gain in Underserved Women.

Economics & Sociology

• Health in Transition: New Evidence on Obesity Dynamics in Post-Soviet Countries.
• (A)symmetries in Beauty-Status Exchange: Spousal Relative Income and Partners’ BMI (at) During Marriage.
• Individual Determinants and Community Moderators of Sports Participation in Adults with Overweight or Obesity: A Hierarchical Linear Model Analysis.
• Dissertation: Consumer Heterogeneity in Demand for Food.

Epidemiology

• Associations between Obesity and the Severity of Occupational Allergic Rhinitis.
• Associations between General and Abdominal Obesity and Oral Health Behaviors.
• Abstract: Epidemiology and Cardiovascular Implications of Preclinical and Clinical Obesity.
• Prevalence and Associated Factors of Obesity, Diabetes, and Hypertension Among University Students in Jordan.
• Obesity, Knowledge, and Perceived Risk: Insights from the ObeCare Project Across Italian Territorial Pharmacies.
• Association between Normal-Weight Central Obesity and Asymptomatic Hyperuricemia in Korean Adults.
• The Combined Impact of Smoking, Alcohol, and Obesity on Past Trends in Educational Inequalities in Life Expectancy in England and Wales, Finland, and Italy, 1990-2017.

Psychology & Neuroscience

• Review: The Role of the Microbiome as a Factor in the Bidirectional Association between Obesity and Depression.
• Review: Psychological and Behavioral Effects of GLP-1 and GIP Agonists in Weight Loss.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Social Determinants of Health and Racial Disparities in Lung Function: Findings from the National Health and Nutrition Examination Survey, 2007-2012.
• The Examination of the Spatial and Contextual Disparities of Determinant Factors of Adult Obesity Among Communities in Chicago.

Stigma

• Internalized Weight Stigma, Metabolic Syndrome, and Inflammation in Postmenopausal Women with Obesity.
• Review: Promoting Resilience in Women's Weight Stigma Management (PRISM): A Model for Enhancing Body Image Resilience.

Policy Related

• Water Promotion for Overweight Prevention in Schoolchildren: For Whom Does It Work Best?
• An Updated Definition of “Healthy” Foods in the United States: How Do They Measure in Nutrient Density, Cost, and Frequency of Consumption?
• Ultra-Processed Food Consumption and Subclinical Cardiac Biomarkers.
• Systematic Review: Towards a Comprehensive School Food Environment Audit Tool in Canada.
• Housing Costs and Food Purchasing Characteristics: The Role of SNAP Participation and SNAP Purchasing Power.
• Review: The ‘Obesity First’ Approach: Redefining the Future of Healthcare.

Intergenerational Effects

• Review: The Impact of Maternal High-Fat Diet on Stem Cell Programming and Disease Susceptibility in Offspring.
• RCT: The Impact of Maternal Supplementation of Fish Oil and/or Probiotics During Pregnancy on the Serum Metabolomic Profile from Infancy to Childhood.
• Mendelian Randomization: Causal Relationship between Multiple Modifiable Risk Factors and Gestational Diabetes Mellitus.
• Adverse Perinatal Outcomes Associated with Macrosomia in Nulliparous Women: A Multicenter Cohort Study.

Ecology, Evolution, & Energetics

• The Contribution of Tissue-Specific Mitochondrial Respiration to Individual Variation in Oxygen Uptake During Rest and Exercise by the Gulf Killifish, Fundulus grandis.
• Preprint: Parental Care at the Molecular Level: The Metabolic Division 2 of Labour between Parents and Offspring.

Methods

• Editorial: Stable Isotopes Can Transform Nutritional Epidemiology - If We Let Them.
• Can Speckle Tracking Echocardiography Unmask Cardiac Involvement in Obesity Hypoventilation Syndrome?
• Tissue Engineered Models of Adipose Tissue Dysfunction to Investigate Obesity-Related Comorbidities.
• New Pediatric Waist-To-Height Ratio Adiposity Cutoff Predicts Adulthood Hypertension: Analysis of 7243 Participants from NHANES 2021-2023.
• RCT: Effect of a Mobile Phone Application for Dietary Self-Monitoring on Obesity in Adolescents.
• Evaluating and Comparing the Predictive Ability with Hypertension Risk Among Obesity Indicators: A Prospective Cohort Integrating Mendelian Randomization Analysis.
• Review: Artificial Intelligence for Obesity Management: A Review of Applications, Opportunities, and Challenges.

Commentary

• Obesity, Treatment, and Kidney Function Assessment.
• The Science and Politics of Food Noise.
• Podcast: Ultra-Processed Foods with Dr. Samuel Dicken on Layne Norton Podcast.
• Podcast: "Science Vs: Seed Oils: Should You Switch to Butter?"
• Five Thoughts to Take Home from ObesityWeek 2025.
• Senotherapeutics for Metabolic Disease and Diabetic Complications.
• LinkedIn: Assessing and Addressing Diet in the Real, Multicultural World.
• A Passionate Debate of the Lancet Commission Report.

General

• Early Oldowan Technology Thrived During Pliocene Environmental Change in the Turkana Basin, Kenya.
• Nuances in Fish Combat: Exploring Male and Female Differences in the Agonistic Behavior of an Amazonian Cichlid.
• Sex Differences in Health Burdens Across the Lifespan in Wild Chimpanzees (Pan troglodytes schweinfurthii).
• Preprint: Regulation of the Dependence Period in Booted Eagles: Effects of Nutritional Conditions.
• Long-Term and Regional-Scale Data Reveal Divergent Trends of Different Climate Variables on Fish Body Size over 75 Years.
• Press Release: Some P53 Mutations Could Help Fight Cancer.
• News: Can Bowhead Whales with Their 200-Year Lifespan Help Us to Slow Ageing? Researchers Find the Longest-Living Mammal Is Particularly Good at Fixing Faulty DNA - and Cold Water May Help.
• Coercive Paternalism Vs. Libertarian Paternalism Vs. Antipaternalism: A Triptych.

Announcements

• Applications Open: Excellence in Nutrition Fellow of the American Society for Nutrition (FASN). Due December 1, 2025.
• Texas Voters OK $3 Billion for New Dementia Research Institute.
• Lawrence J. Cheskin Named Recipient of the Obesity Society’s 2025 Atkinson Stern Award for Distinguished Public Service.

Featured

• Diagnostic Ultrasound Irradiation Combined with Microbubbles to Modulate Carotid Body Activity for the Treatment of Obesity-Related Hypertension in Rabbits.
• Weightlifting Outperforms Voluntary Wheel Running for Improving Adiposity and Insulin Sensitivity in Obese Mice.
• Targeting the MTOR-Mitochondrial Function Axis: Calcitriol Attenuates Sarcopenic Obesity with Lipid Dysregulation Etiology [in Mice].

Headline vs Study

• Headline: What? I Can't Have Bacon in My Full English Breakfast Now?
• Headline: Bacon and Ham Linked to Cancer Risk - Here's What Scientists Want You to Know.
• Letter: Coalition Against Nitrites Call for Action on Nitrite-Cured Meats in Reference to Ten Year Old WHO IARC Report. No New Evidence Presented; Nothing Preventing Your Full English Breakfast.

Contrary or Null Findings

• RCT: "None of the [physical activity promotion and micronutrient supplementation] interventions significantly improved daily PA…[and] the PA + MMNS arm increased body fat percentage…".
• RCT: "After controlling for age, BMI, sequence and period, there were no condition*time interactions for IL-6 (primary endpoint)..." [in] "Inflammatory Cytokine Responses to Six Weeks of Increased Dairy Intake in Individuals with Overweight and Obesity".
• RCT: "Despite lower adherence in the high-dose group, adherence showed little association with clinical outcomes. These results suggest that high adherence to high-dose exercise may not be necessary for short-term benefit..." in knee osteoarthritis.
• RCT: No Significant Impact of Nutrition Counselling Via Online Application on Nutrient Intake Among Thai Older Adults During COVID-19.
• RCT: "Metformin did not reduce [low risk prostate cancer] progression in men with low-risk PCa on AS....In prespecified subgroup analysis, metformin was associated with increased pathologic progression among obese patients (BMI ≥ 30; HR, 2.36 [95% CI, 1.21 to 4.59]; P = .0092)."
• RCT: Metformin "blunts exercise training-mediated increases in vascular insulin sensitivity at the levels of conduit arteries and capillaries..."
• RCT: No Effect of "Disclosure of Genotype Information to Reduce Caffeine Intake in Slow Metabolizers: Findings from RCT on Personalized Dietary Interventions.”
• RCT: No significant "effects of digital health intervention (DHI) or/and personalized healthy breakfast guidance (PHBG) on ...body composition of young adults in Tianjin..."

Basic

• Short-Term Exposure to Lauric Acid Promotes Adipose Tissue Lipolysis and Reduces Leptin Expression Via a PPARγ-Dependent Mechanism.
• Leucine Inhibits Degradation of Outer Mitochondrial Membrane Proteins to Adapt Mitochondrial Respiration.
• Review: Tracing the Path from Obesity to Diabetes: How S-Allyl Cysteine Shapes Metabolic Health.
• Preprint: Mitochondrial Uncoupler BAM15 Improves Skeletal Muscle Function and Mitochondrial Respiration in Sarcopenia.

Scientific Rigor & Scholarly Dialogue

• PubPeer Comments On: Protective Effect of Vitamin D Supplementation on COVID-19-Related Intensive Care Hospitalization and Mortality: Definitive Evidence from Meta-Analysis and Trial Sequential Analysis.
• Retraction: Argano et al. Protective Effect of Vitamin D Supplementation on COVID-19-Related Intensive Care Hospitalization and Mortality: Definitive Evidence from Meta-Analysis and Trial Sequential Analysis. Pharmaceuticals 2023, 16, 130.
• Meta-Analysis of RCTs: "Acute exercise significantly improved executive function (moderate evidence, 9 studies, 330 participants, g = 0.33, small effect, 95% CI, 0.07-0.59, P = .01, I2 = 26.77%). However, this was only for high risk of bias/crossover studies."
• Retraction: Sesame Oil and Vitamin E Co-Administration May Improve Cardiometabolic Risk Factors in Patients with Metabolic Syndrome: A Randomized Clinical Trial.

Clinical

• Combining Medications with Bariatric Surgery to Treat Obesity.
• Long-Term Administration of Liraglutide for Weight Management in Pediatric Patients Under 18 Years: Evidence from 7 RCTs.
• Exploring the Relationship between Obesity, Weight Loss and Health-Related Quality of Life: An Updated Systematic Review of Reviews.
• To What Extent Do Clinical Practice Guidelines for Chronic Diseases Embrace Current Obesity Management Guidance? A Qualitative Content Analysis.

Children and Adolescents

• Jumping Hurdles: A Grounded Theory Study of Factors Influencing School Nurses' Role in Pediatric Obesity Prevention in Saudi Arabia.
• Tiered School-Family-Clinic Intervention for Childhood Obesity Prevention in China.
• A Prospective Cohort Analysis from Germany Shows Transition Into Adulthood Is an Underestimated Vulnerable Period for Children with Overweight/Obesity.

Surgery

• Abstract: The Impact of Bariatric Surgery on Pancreatic Adenocarcinoma and Exocrine Pancreatic Insufficiency Risk in Patients with Chronic Pancreatitis and Morbid Obesity: A National Readmission Database Analysis.
• ANGPTL8 Is Upregulated in Subcutaneous Adipose Tissue at Early Term After Bariatric Surgery in Patients Living with Obesity.
• Metabolic Bariatric Surgery in Older Patients: Is It Worth It? BARI-10-POL Study.
• Retrospective Study: Bariatric Surgery: Pre-Operative Comorbidities, Postoperative Results, and Complications.

Drugs

• Commentary: Tirzepatide and the NHS: Are We Creating a Two-Tier Obesity Treatment System?
• Thermogenic Targets for Obesity Management in the Era of Incretin-Based Therapies.
• “The New DNP”: Discussion of the Experimental ‘Fat Burner’ BAM15 on Bodybuilding Forums and YouTube.

Food & Diet

• Ketogenic Diet Modulates Gut Microbiota–Brain Metabolite Axis in a Sex- and Genotype-Specific Manner in APOE4 Mice.
• Soy Protein Outperforms Whey Protein in Ameliorating Insulin Resistance but Not Obesity in High-Fat Diet-Induced Obese Mice.
• High Consumption of Ultra-Processed Foods Is Associated with Genome-Wide DNA Methylation Differences in Women: A Pilot Study.

Caloric and Dietary Restriction

• Comparison of an Energy-Reduced Mediterranean Diet and Physical Activity Versus an Ad Libitum Mediterranean Diet in the Prevention of Type 2 Diabetes: A Secondary Analysis of a RCT.
• Intended Isocaloric Time-Restricted Eating Shifts Circadian Clocks but Does Not Improve Cardiometabolic Health in Women with Overweight.
• Semaglutide Versus Caloric Restriction-Induced Weight Loss: Insights Into Effects on Skeletal Muscle Mass and Function.

Exercise & Physical Activity

• Sex Differences in Upper-Body Strength, Lean Mass, and Bone Density Across the Adult Lifespan: Insights Into Musculoskeletal Aging and Strength Preservation.
• Effects of 8-Week High-Intensity Interval Training Intervention Regulating the SIRT1/PGC1α Pathway on Hippocampal Neuron Injury and Cognitive Impairment in Obese Rats.
• Impact of an 8-Week High-Intensity Bodyweight Interval Training on Body Composition and Blood Lipid Metabolism in Young Women with Overweight.

Economics & Sociology

• Impact of Sugar-Sweetened Beverages Tax on Obesity and Obesity-Related Health Conditions: Evidence from Washington State’s Soft Drink Syrup Tax.
• Incident Cases and Healthcare Costs of Non-Communicable Diseases Attributable to Industrialized and Total Sugar Sweetened Beverage Intake in Mexico.
• Factors Shaping Dietary Choices of Black African Immigrant Women with Overweight and Obesity from West Africa Living in the UK.

Epidemiology

• Rising Trends in Obesity and Heart Failure: Related Mortality in the United States, 1999-2024.
• Prevalence of Overweight, Obesity and Underweight and Associated Factors in a Three-Generation Population-Based Study in a Large Russian Region.
• Long-Term Waist Circumference and Diabetes Risk in Premenopausal Women: Role of Shared Risk Factors.

Psychology & Neuroscience

• The Influence of Referral, Initial Assessment, and Logistical Factors on Dropout at an Adult Weight Management Service: A Semi Structured Interview Study.
• Weight Loss After Obesity Disrupts Cognitive Flexibility Through Reinforcement Learning Strategies.
• Do We Just Need to Eat Less Often? An Update on the Role of Eating Frequency and Intermittent Fasting for Obesity Prevention and Management.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Disparities and Trends in Pulmonary Embolism Mortality with and Without Obesity: A Nationwide U.S. Analysis.
• Abstract: Demographic and Regional Disparities in GLP-1 Receptor Agonist Clinical Trials for Weight Loss: A Comparative Meta-Analysis of US and International RCTs.
• Anthropometric Indices of Obesity and Their Relationships with Diabetes Risk by Race and Ethnicity Among Postmenopausal Women.

Ethics

• Big Data, Machine Learning, and Personalization in Health Systems: Ethical Issues and Emerging Trade-Offs.
• Report: Science in the Age of AI: How Artificial Intelligence Is Changing the Nature and Method of Scientific Research.

Stigma

• Family-Based Weight Stigma and Psychological Well-Being of Adolescents: A Longitudinal Analysis of Recent Vs. Cumulative Exposure.
• Weight Stigma and Implicit Bias in Healthcare: Investigating the Impact of Women's Body Size on Continuity of Care and Communication About Sexual and Reproductive Health.
• Understanding Overweight and Obesity: Contemporary Evidence-Based Approaches to Delivering Person-Centred Nursing Care.

Policy Related

• RCT: Nutrition Info and Other Front-Of-Package Labels and Simulated Food and Beverage Purchases.
• The Undernourished Curriculum: What Happened to Nutritional Education in the Medical Curriculum?
• Examining Effective Translation and Implementation Methods for Equitable Access and Scaling of Nutrition Programs - A Report from the “Biomarkers of Nutrition for Development: Knowledge Indicating Dietary Sufficiency (BOND-KIDS)” Project Working Group 4.

Intergenerational Effects

• Discovery of Obesity Genes Through Cross-Ancestry Analysis.
• Relationship between Maternal Obesity, Birth Weight, and Fetal Adiponectin/Leptin Ratio: A Potential Early Biomarker of Cardiometabolic Risk.
• Epigenetic Mediation May Explain Intergenerational Associations between Maternal Obesogenic Lifestyle and Children’s Birth Weight: Findings from the NorthPop Prospective Birth Cohort.

Ecology, Evolution, & Energetics

• Lipolysis Gone Rogue: The HSL Connection in Feeding Cancer.
• Is the vLamax for Glycolysis What the VO₂max Is for Oxidative Phosphorylation?
• Shifts in Salamander Body Size Associated with 60 Years of Climate Change.

Methods

• Performance Evaluation of 3 Large Language Models for Nutritional Content Estimation from Food Images.
• ToF Based Wearable Sensing for Passive Food Intake Monitoring.

Commentary

• Anti-Obesity Medications Set to Explode Entering 2026.
• Podcast: Strength Training and Myokines: Unlocking Exercise as Medicine.
• Advancing Policy, Systems and Environmental Change Research to Reverse Upward Trends in Obesity Prevalence - A New Call to Action.
• Should Young People Take Creatine?
• Emerging Challenges in the Epidemic of Diabetes and Obesity: The Need for Evidence-Based and Policy-Oriented Strategies.
• Seriously, Can Use of GLP-1s Lower Obesity Prevalence?
• Podcast: Weight Bias, Diabetes Distress & Trauma Informed Care – Dr. Robyn Pashby.
• Today’s ‘Skinny Influencers’ are Selling Something More Mind-Bending Than Weight Loss.

General

• Novel Approach Restores Sperm Production in Mouse Model of Infertility.
• RCT: Sensory Trial of Camel Milk Powder Among Pastoralist Communities of the Somali Region, Ethiopia.
• Meta-Analysis of RCTs: "Overall, inositol may offer modest cardiometabolic benefits, with moderate-to-high certainty for improvements in insulin resistance and lipid profiles. However, existing studies show a high risk of bias and low certainty of evidence, particularly for anthropometric outcomes, creating cautious interpretation."
• RCT: "An 8-week pickleball program significantly improved balance, gait, and social engagement in older adult women."
• RCT: "For patients with degenerative meniscal tear and knee pain, the addition of physical therapy or text messages to encourage adherence to home exercises was not superior in reducing pain to a home-exercise program alone."
• Why Psychopathology Research Should Avoid Studying One Mental Disorder at a Time: An Intergenerational and Developmental Evidence Base for Understanding “p”.
• Fruit Flies Offer New Insights Into How Human Alzheimer’s Disease Risk Genes Affect the Brain.
• Perceptions of Food and Alcohol Disturbance: A Vignette Experiment Examining the Role of Gender and Calorie Restriction Motive.
• Saying ‘No’ with Confidence: Statistical Approaches to Test for the Absence of an Effect.
• Obesity Rates by Country 2025.

Video & Audio

• Podcast: How Much Should Healthy Medical Research Volunteers Get Paid?

Announcements

• 125 Years of Discovery, Care and Impact: The Legacy and Future of Baylor College of Medicine.
• Call for Abstracts: American Society for Nutrition's NUTRITION 2026.
• David B. Allison, PhD (Baylor College of Medicine), Lauren Hunt, PhD, RN, FNP (UCSF), and Arlan Richardson, PhD (University of Oklahoma Health Sciences) to Receive AFAR Annual Scientific Awards of Distinction.

Featured

• Dietary Assessment at the Confluence of Public and Planetary Health: Introduction of the DIEM (Dietary Impacts on Environmental Measures) Scoring System.
• Meta-Analysis: Effects of GLP-1 Receptor Agonists on Cognitive Function in Patients with Type 2 Diabetes.
• Commentary: Impact of Resistance Training Intensity on Body Composition and Nutritional Intake Among College Women with Overweight and Obesity.
• Metabolic Impact of Dietary Glycine Supplementation in Individuals with Severe Obesity.

Headline vs Study

• Headline: Keto Diet Dangers? New Research Links Obesity-Related Fatty Acids and Breast Cancer.
• Study: Blood lipids, diets, obesity, and exogenously injected tumor cells... in mice. "Obesity-related fatty acids" not studied.

Contrary or Null Findings

• "In PWH [persons with HIV] receiving semaglutide for MASLD, despite decreased psoas muscle volume, there was no significant change in physical function, suggesting function was maintained despite significant loss of muscle."
• Time-Restricted Feeding Provides Limited Microglial Immunometabolic Improvements in Diet-Induced Obese Rats.
• Interleukin-6 Blockade Does Not Impair Exercise-Induced Glucose Uptake and Insulin Sensitivity in Rheumatoid Arthritis.
• RCT: Ingestion of 20g Whey or Canola Protein Does Not Further Increase Muscle Protein Synthesis Rates During Recovery from Resistance Exercise in Healthy, Young Females.
• The GMI/HbA1c Ratio Does Not Independently Predict Diabetic Retinopathy in Adults with Type 1 Diabetes.
• RCT: "This 14-day preoperative exercise and nutritional intervention program did not significantly reduce postoperative complications in frail older patients with gastrointestinal cancer..."
• RCT: "Improvements in fitness and diet composition were not associated with changes in BCAA concentrations independent of weight loss."
• Meta-Analysis of RCTs: "Post-exercise stretching, when used as a standalone recovery intervention, does not significantly improve soreness, strength, performance, flexibility, or pain threshold."

Basic

• The Anti-Obesity Effects of Clostridium butyricum B-3 and Its Impact on Gut Microbiota.
• Adipocyte Calpain-2 Deficiency Reduces Obesity-Accelerated Abdominal Aortic Aneurysm Formation in Mice.
• Review: The Intricate Nexus: The Relationship between Oxidative Stress and Inflammation in Obesity.
• Thesis: The Role of Plakoglobin in Adipocyte Expansion and Obesity.
• Triclosan Induced Obesity Via Gut Microbiota Dysbiosis and Butyrate Reduction.
• Inhibition of Endocannabinoid Synthesis Enzymes DAGL and NAPE-PLD Transiently Lowers Body Weight and Alters Glucose Homeostasis During a High-Fat Diet Challenge in Mice.

Scientific Rigor & Scholarly Dialogue

• U.S. Obesity Prevalence: “Good News” or “Astounding” Surge?
• Preprint: Why Causal Effects of Ultra-Processed Foods Cannot Be Identified: A Systematic Review of Subtypes of Ultra-Processed Foods and Risk of Type 2 Diabetes.

Clinical

• Causal Relationships between Modifiable Risk Factors and Heart Failure.
• RCT: Dietary Patterns and Change in Food Consumption in Breast Cancer Survivors with Overweight or Obesity.
• RCT: Effects of Asparagus Powder Supplementation on Glycemic Control, Lipid Profile, and Oxidative Stress in Adults with Overweight or Obesity.

Children and Adolescents

• Associations of Child and Adolescent Obesity with the Risk of Neuroinflammatory Diseases: Analysis of Data from a Global Health-Care Database.
• Obesity Trends and Early-Life Risk Factors in Preschool Children in Northwest China from 2012 to 2024.
• RCT: Partially Hydrolyzed Formula on Comfort Measures in Fussy Infants.

Surgery

• Systematic Review: Factors That Influence an Individual's Decision to Undergo Bariatric Surgery.
• Evolving Workload Disparities between High- and Low-Volume Bariatric Surgeons: Implications for Surgical Quality and Training Policy - Insights from Taiwan’s Nationwide Data (2016-2024).
• Narrative Review: Positive End-Expiratory Pressure Optimisation During General Anaesthesia in Patients with Obesity.
• Retrospective Study: Perioperative Airway Events in Pediatric Patients with Obesity Undergoing Bariatric Surgery.
• Commentary: Reflections on Speech-Language-Hearing Therapy in Obesity and Bariatric Surgery.

Drugs

• The Cost-Effectiveness of Subcutaneous Semaglutide 2.4mg in the Management of People Living with Obesity and Prediabetes in England.
• A Preliminary Study of the Physiological and Perceptual Effects of GLP-1 Receptor Agonists During Alcohol Consumption in People with Obesity.
• Meta-Analysis: Glucagon-Like Peptide-1 Receptor Agonist Treatment Reduces Body Weight and Improves Glycaemic Outcomes in Patients with Concurrent Overweight/Obesity and Type 1 Diabetes.
• Eloralintide (LY3841136), a Novel Amylin Receptor Agonist for the Treatment of Obesity: From Discovery to Clinical Proof of Concept.
• Abstract: Semaglutide Use Associated with Lower Blood Pressure in Patients with Cardiometabolic Multimorbidity.

Food & Diet

• Commentary: The Case for Stronger Government Action on Ultraprocessed Foods.
• Protective Effects of Traditional Herbal Teas Against Obesity-Induced Hepatic and Hormonal Alterations in Rats.
• Food Group Intake and Mediterranean Diet Adherence Among a Representative Sample of Spanish Middle-Aged and Older Adults. Are We Still on Track?
• A Cross-Sectional Analysis of Baseline Diet Quality Among Participants Enrolled in Delicious Eating for Life in the Southern Homes Weight Loss Randomized Trial.

Caloric and Dietary Restriction

• RCT: Association between Physical Activity Energy Expenditure and Markers of Healthspan During Prolonged Calorie Restriction in Individuals Without Obesity.
• The Effects of Time-Restricted Feeding on Early Vascular, Liver, and Renal Structural Changes, Oxidative Stress, and Inflammation in Obese Rats.
• Causal Relationships between Popular Diets (Low-Calorie, Vegetarian, and Gluten-Free Diets) and Inflammatory Skin Diseases.
• Review: Circadian Nutrition and Obesity: Timing as a Nutritional Strategy.

Exercise & Physical Activity

• Meta-Analysis: Effectiveness of Theory-Based Physical Activity Interventions in Preventing Childhood Obesity.
• Handgrip Strength and Trajectories of Preclinical Obesity Progression: A Multistate Model Analysis Using the UK Biobank.
• The Potential Mediating Role of Good Mental Health on the Relationship between Low Physical Activity and High Screen Time with Executive Functions in Chilean Children and Adolescents.

Economics & Sociology

• The Economic Impact of Diabetes: Assessing Incremental Direct Costs in Australia Using Linked Administrative Data.
• Impact of BMI and Comorbidities on Health-Related Quality of Life and Work Productivity in People with Overweight or Obesity.

Epidemiology

• Implications of a New Obesity Definition Among the All of Us Cohort.
• Cardiometabolic Outcomes Among Adults with Abdominal Obesity and Normal BMI.
• State of Obesity Report 2025: Better Policies for a Healthier America.
• Trends in Cancer Incidence in Younger and Older Adults: An International Comparative Analysis.
• Different Metabolic Phenotypes of Obesity and Risk of Peripheral Artery Disease.

Psychology & Neuroscience

• Review: Multidimensional Sleep Health: Definitions and Implications for Cardiometabolic Health: A Scientific Statement from the American Heart Association.
• Review: Obesity, Hypertension and Brain Health.
• Meta-Analysis: Associations of Weekday-To-Weekend and Day-To-Day Sleep Differences with Adiposity-Related Measures in Children and Adolescents.
• Review: Modulating Metabolism and Reproductive Health Through Microbiome Driven Gut-Brain Axis Therapies.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Perspectives on Obesity Health Risks and Related Contributing Factors.
• Fostering Equity in Nursing Education and Practice: Inclusive Simulation for Weight Bias Reduction.
• Influence of National Income, Population, and Waste Emissions on Food Security Utilization: New Evidence Related to Saudi Arabia's Obesity.
• Abstract: Mortality Trends and Disparities for Essential Hypertension with Obesity in the United States.
• Exploring the Interaction between Ethnicity, Deprivation and the Use of CGM on Diabetes Outcomes.

Stigma

• Weight Discrimination and Eating Disorder Symptoms in Early Adolescence.
• Weight Stigma Is Highly Prevalent in a National Sample of Sexual Minority Women.

Policy Related

• Food Insufficiency and Difficulty Affording Expenses After the End of Supplemental Nutrition Assistance Program Emergency Allotments in the United States Among Households With and Without Children.
• “High-In” Front-Of-Package Labeling of Foods High in Added Sugars, Sodium, and Saturated Fat.
• Review: Nutrition Services in the Primary Healthcare System.
• Impact of Deimplementing Universal Free School Meals: School Food Authority Perspectives.
• Financing and Prioritizing Diabetes and Other Non-Communicable Diseases in Ghana: A Qualitative Policy Analysis of the Barriers, Enablers and Opportunities.

Intergenerational Effects

• Review: Role of Epigenetic Markers in Cardiovascular Disease Following Hypertensive Disorders of Pregnancy.
• Effects of Gestational Diabetes Mellitus on Maternal and Neonatal Outcomes in Northern Sri Lanka.
• Impact of Maternal High-Fat Diet on Offspring Cardiovascular-Kidney-Metabolic Health: Spotlight on Oxidative Stress.
• Chapter: Neonatal and Childhood Consequences of Maternal Obesity and Diabetes.

Ecology, Evolution, & Energetics

• Drought Intensity and Duration Interact to Magnify Losses in Primary Productivity.
• Air Pollution Modulates Brown Adipose Tissue Function Through Epigenetic Regulation by HDAC9 and KDM2B.
• Fagopyrum esculentum Polysaccharides Mitigate Obesity by Reshaping Gut Microbiota and Enhancing Lipid Metabolism in High-Fat Diet-Fed Mice.
• Adipose Tissue-Specific Yap Knockout Exacerbates Diet-Induced Obesity Through Suppression of Lipolysis.

Methods

• Distinguishing Diet- and Microbe-Derived Metabolites in the Human Gut.
• ByteTrack: A Deep Learning Approach for Bite Count and Bite Rate Detection Using Meal Videos in Children.

Mathematical and Quantitative

• Evaluating the Association between TSH and FT4 Levels and the Incidence of Metabolic Syndrome: Insights from the Tehran Thyroid Study Using Joint Modeling.

Commentary

• Hot Yoga Doesn’t Deliver on Heart Health Promises. Study Shows What Really Works.
• Will FDA Require an Ineffective Front-Of-Pack Label for Food?
• Myostatin Blocker Preserves Muscle with GLP-1 Treatment.
• Strategies for Weight Management in Children and Adolescents: Self-Regulated Nutrition, Family-School Collaboration, and Social Environment Optimization.
• Review: Vitamin D and Cardiovascular Risk in Children with Obesity in Saudi Arabia.
• Redefining Obesity - Too Much Is Never Enough.
• Podcast: Ultraprocessed Foods in Focus: How Is the Food Industry Responding? - Rocco Renaldi.
• Review: The Intricate Nexus: The Relationship between Oxidative Stress and Inflammation in Obesity. (pdf)

General

• Spurious Precision in Meta-Analysis of Observational Research.
• A New Analytical Tool to Optimize the Potency and Selectivity of Drugs.
• Still No Evidence for an Environmentally Responsive Epigenetic Clock in an Insect.
• A CGAS-Mediated Mechanism in Naked Mole-Rats Potentiates DNA Repair and Delays Aging.
• Global Burden of 292 Causes of Death in 204 Countries and Territories and 660 Subnational Locations, 1990-2023: A Systematic Analysis for the Global Burden of Disease Study 2023.
• Sex-Specific Longitudinal Reversal of Aging in Old Frail Mice.
• TOR Inhibitors Could One Day Be Multi-Purpose Healthspan Drugs.
• In Overlooked Cellular Connections, This Researcher Charted Zika’s Path to the Placenta.

Announcements

• Webinar Registration: SWEET PERCEPTIONS: RD Perceptions & the Science on Low- & No-Calorie Sweeteners. November 3, 2025.
• Webinar Registration: Longevity & Healthy Aging - How Can We Achieve a Longer and Healthier Life.
• Workshop: Ultra-Processed Foods: Definitions, Implications, and Regulations - 22 Oct 2025, 5:00 PM - 8:00 PM, Kent College of Law, 565 W. Adams St., Chicago IL.

Featured

• Development and Rigorous Multistep Validation of a Psychometric Tool to Measure Food Noise.
• Selective Agonism of Liver and Gut FXR Prevents Cholestasis and Intestinal Atrophy in Parenterally Fed Neonatal Pigs.
• Timing and Duration of Calorie Restriction Determine Its Impact on Ovarian Aging in Female Mice.
• "Overall, our study found inconclusive evidence on the benefits of [Community Based Interventions]." in ... "Systematic review on community-based interventions targeting prevention of overweight and obesity in children and adolescents."
• Why Did Bob Stop Losing Weight? We Need to Talk About Energy Expenditure Compensation.

Headline vs Study

• Headline: Science Confirms Your Daily Brew Really Does Make You Happier.
• Press Release: Your Morning Coffee Really Does Make You Happier.
• Study: Observational study of self-reported caffeine consumption (not necessarily coffee) and reported affect. "[T]he reliance on self-reported measures introduces the potential for bias, and the observational nature of the study limits causal inferences."

Contrary or Null Findings

• RCT: No Significant Effect of a Multifaceted Digital Intervention for the Prevention of Type 2 Diabetes Mellitus in Primary Care (PREDIABETEXT) on Primary Endpoint of HBA1c.
• Preprint: "Contrary to the dominant paradigm and practice in the probiotic field, combining multiple probiotic strains did not necessarily increase efficacy. Simultaneous treatment with EcN and L. murinus V10 was less effective than EcN treatment alone at preventing death from sepsis."
• "Our findings demonstrate that, in accordance with human studies, ActRIIA/IIB blockade holds promise for increasing muscle mass, strength, and muscle insulin sensitivity. However, contrary to the improved glycemic control in humans, ActRIIA/IIB blockade in mice causes severe glucose intolerance and lowers voluntary physical activity."
• RCT: An Enhanced Implementation Support Approach Was Not Superior to Less Intensive Foundational Implementation Support for Promoting Delivery of a Group Physical Therapy Program for Knee Osteoarthritis.
• "Fmr1 KO mice with or without metformin treatment displayed hyperphagia on a HFD, yet did not show higher weight gain than wild type. And, surprisingly, their glucose tolerance was equivalent to that of wild type mice on metformin."
• "Surprisingly, [physically] active women reported more depressive symptoms...".
• RCT: "...even among highly motivated and digitally engaged participants, diet self-monitoring via the app alone did not lead to participants meeting the clinically recommended dietary fiber intake."
• "Contrary to our hypothesis, we observed a downward BMI trajectory back to baseline with the exception of those with residential instability in the post-COVID-19 pandemic period following a statistically significant weight gain during the pandemic."

Basic

• Molecular Signature of Early Obesity-Associated Insulin Resistance: Adipocyte-Derived Extracellular Vesicle Proteins Reveal Stage-Specific Candidates for Metabolic Dysfunction.
• MRAP2 Modifies the Signaling and Oligomerization State of the Melanocortin-4 Receptor.
• Reduced Growth and Inflammation in Lrp5−/− Mice Adipose Tissue.
• Macrophage Plg-RKT Expression Promotes Diet-Induced Obesity and Metabolic Dysfunction-Associated Steatotic Liver Disease.
• GHSR Suppression in Neurons Protects Against Aging-Associated Metabolic and Cognitive Impairments.

Scientific Rigor & Scholarly Dialogue

• Correspondence: Interpreting Substitution Models in Nutritional Epidemiology: The Case for the Protective Role of NOVA 1 Foods over the Risk of NOVA 4.
• Article: Effects of Chronic Nitrate Supplementation on Blood Pressure in Adults: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
• Letter: The Devil Is in the Details: Reassessing an Isolation Attempt Reveals Methodological Breaches in Dietary Inorganic Nitrate Research.
• Reply: The Light Is in the Details: Transparent Methodology and Scientific Integrity in Systematic Review Design.
• Follow-up Letter: Robustness Is Action, Not Assertion: Reassessing an Isolation Attempt Reveals Methodological Breaches in Dietary Inorganic Nitrate Research.

Clinical

• RCT: Mixed-Meal Challenge Differentially Modulates Metabolic Pathways in Adipose Tissue in Healthy Subjects with Abdominal Obesity who had High Versus Low Liver Fat.
• RCT: The Impact of Smoking Reduction on Food Demand in People with Excess Weight.
• RCT: Reduction of Muscle Damage Indices by Consuming Chlorella vulgaris Along with High-Intensity Interval Training in Men with Overweight.
• RCT: Effect of Weight Loss Through Dietary Interventions on Cardiometabolic Health in Older Adults.
• RCT: Early Weight Loss and Other Factors Associated with Clinically Significant Weight Loss in Two Commercial Weight Loss Programmes.
• Integration of Proteomic and Lipidomic Analysis Reveals Potential Markers of Insulin Resistance in Young Children with Obesity.
• The Skeletal Muscle-Adipose Creatine Metabolic Axis: A Novel Paradigm for Lipid Metabolism Reprogramming and Obesity Management.
• Systematic Review: The Impact of Obesity on Influenza Vaccine Immunogenicity.

Children and Adolescents

• Eccrine Sweat Reveals Normalization of Artificial Sweetener Levels in Children with Overweight After Nutritional Education.
• Overview of Systematic Reviews on Behavioral Determinants of Physical Activity and Healthy Eating in Schoolchildren.
• Thresholds of Fat Mass Index Percentiles and Their Association with Cardiovascular Risk in Adolescents: Results from the EVA4YOU Study.
• RCT: Inulin Supplementation Modulates Gut Microbiota Derived Metabolites Related to Brain Function in Children with Obesity.

Surgery

• Systematic Review: Magnetic Sphincter Augmentation Versus Fundoplication in Gastroesophageal Reflux Disease (GERD) Patients without Obesity.
• Review: Sleeve Plus Procedures.
• The Role of X-Ray Densitometry in Diagnosing Calcium Metabolism Disorders in Patients After Bariatric Surgery.
• A Case Series Analysis of Hospital Volume in a New Era of US Bariatric Surgery Within the Nationwide Readmissions Database.
• Health and Economic Gains from Bariatric Surgery in Portugal: An In-Depth Analysis Using a Markov Model.

Drugs

• Blinded by the Drug? A Vigilyze Signal Linking Semaglutide to NAION [Non-Arteritic Anterior Ischemic Optic Neuropathy].
• "Early metformin treatment in overweight or obese individuals may reduce [post–COVID-19 condition] risk."
• Cost-Effectiveness of Semaglutide 2.4 mg Versus Liraglutide 3 mg for the Treatment of Obesity in Greece.
• Discovery of MKP10241, a Novel Small Molecule Targeting the GPR119/Incretin Axis to Treat Metabolic Disorders.

Food & Diet

• RCT: Effect of Sweeteners and Sweetness Enhancers on Weight Management and Gut Microbiota Composition in Individuals with Overweight or Obesity.
• Review: Tropical Plants to Reduce Chronic Metabolic Diseases in the Obesity Pandemic.
• RCT: Effect Modifiers of the MIND Diet for Cognition in Older Adults: The MIND Diet Trial.

Caloric and Dietary Restriction

• Association between Physical Activity Energy Expenditure and Markers of Healthspan During Prolonged Calorie Restriction in Individuals Without Obesity: Observations from the CALERIE RCT.
• Preprint of Meta-Analysis: Time-Restricted Eating Versus Calorie Restriction for the Management of Metabolic Syndrome.

Exercise & Physical Activity

• RCT: Combined Creatine and HMB Co-Supplementation Improves Functional Strength Independent of Muscle Mass in Physically Active Older Adults.
• A Long-Duration Physical Literacy Intervention to Improve Health Indicators and Physical Activity Levels in Adolescents with Overweight or Obesity.
• RCT: Lemon Myrtle Extract Enhances Muscle Hypertrophy Induced by Low-Load Bodyweight Resistance Training in Older Adults.

Economics & Sociology

• Exploring Maternal Health, Lifestyle, and Socioeconomic Influences on Childhood Obesity in Australia.
• Obesity Indices and Their Sociodemographic, Lifestyle, and Social Isolation Correlates in a Large Spanish Working Population.
• Does Loneliness Impact Intentional Weight Loss? The Role of Obesity-Related Disadvantages and Comorbidities.

Epidemiology

• Obesity and Weight Change During Eight Years in Relation to Asthma Incidence.
• Pooled Prevalence and Factors of Overweight/Obesity Among Women of Reproductive Age in Low and Middle-Income Countries with High Maternal Mortality: A Multi-Level Analysis of Recent Demographic and Health Surveys.
• The Weight of Risk: Epidemiological Trends in Cardiac Arrest Mortality Among Adults with Obesity in the United States (1999-2023).
• Association between Dietary Patterns and Obesity-Related Metabolic Phenotypes in Chinese Middle-Aged and Older Adults.

Psychology & Neuroscience

• Associations of Dietary Mineral Intakes with the Risk of Six Common Mental Disorders.
• A New Lens on Childhood Obesity: Developing and Validating the Obesity-Related Well-Being (ORWB) Scale for Assessing Well-Being in Children and Adolescents with Obesity.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Unfavorable Social Determinants of Health and Obesity: A Double Jeopardy for Premature Mortality.
• Exploring Correlates of 6-Month Weight Loss Among Black United States Veterans Entering Veterans Health Administration Behavioral Weight Management Care.
• The Burden of Inequity: Income Related Disparities in Cardiovascular Risk Factors in Europe.
• The EAT-Lancet Commission on Healthy, Sustainable, and Just Food Systems.

Stigma

• Associations between BMI, Body Size Perception, and Dropout from Upper Secondary Education: A Prospective Cohort Study of 15-19-Year-Old Adolescents.
• Supporting Weight Focused Discussions in Primary Care: Barriers and Facilitators.
• The Weight of Weight: The Salience of Body Weight in the Impression Formation Process.

Policy Related

• RCT: Optimal Design of an Added-Sugar Menu Warning Label.
• Systematic Review: Food Service Professionals' Perspectives on the Barriers and Facilitators to the Implementation of Nutrition Standards for School Food: A Mixed-Methods Systematic Review.
• Analysing Celebrity and Influencer Marketing of Food and Beverages to Adolescents on Instagram.
• Integrating Registered Dietitian Nutritionists’ Medical Nutrition Therapy Benefit Into Existing State Medicaid Coverage and Reimbursement Policy.
• Public Attitudes Towards Obesity Policies on the Island of Ireland; Exploring the Relationship with Biopsychosocial Characteristics.

Intergenerational Effects

• Assessing the Risk Factors and Establishing Multivariable Prediction Models for Singleton Macrosomia.
• Impact of Maternal Obesity on Neonatal TSH Levels.

Ecology, Evolution, & Energetics

• Microbiome Characterization of a Pre-Hispanic Man from Zimapán, Mexico: Insights Into Ancient Gut Microbial Communities.
• The Effect of a Kibble Diet Versus a Raw Meat-Based Diet on Energy Metabolism Biomarkers in Dogs.
• Divergent Selection Alters Metabolism and Body Temperature in Obese Mice.
• Effect of Female Body Size on Courtship Preferences of Males in Two Pierid Butterfly Species: Pieris melete and P. napi.

Methods

• Machine Learning Framework for Predicting Susceptibility to Obesity.
• Obesity Prediction Using Machine Learning Algorithms.

Commentary

• Review: Impact of Anabolic Steroids on Tendons.
• In Favor of a Prediabetes Indication for GLP-1s.
• Novel GLP-1-Based Medications for Type 2 Diabetes and Obesity.
• Weight Loss Drug Stigma Shows Society Still Holds Negative Attitudes Towards Body Weight and Obesity.
• Food Formulation and Precision Nutrition in the Ozempic Era: ‘There’s an Entire Secondary Market That Can Come from Any Breakthrough Technology’.
• Toby Carvery Has Made a Huge Change in All of Its 158 Restaurants Due to New Nanny State Obesity Rules.
• The SWEET Spot for Weight Maintenance.
• Fear, Food & False Claims: How Nutrition Myths & Politics Distract from Real Health.
• The Body Mass Index: What’s the Use?

General

• Association of Genetic Scores Related to Insulin Resistance with Neurological Outcomes in Ancestrally Diverse Cohorts from the Trans-Omics for Precision Medicine (TOPMed) Program.
• Performance of an Automated Sleep Scoring Approach for Actigraphy Data in Children and Adolescents.
• Influence of Varying Proximity-To-Failure on Muscular Adaptations and Repetitions-In-Reserve Estimation Accuracy in Resistance-Trained Individuals.
• Deeper Microchimerism Study Sheds New Light on a Mother’s Cellular Gift.
• Extinct Megafauna Dominated Human Subsistence in Southern South America Before 11,600 Years Ago.
• Density-Dependent Recruitment but Not Survival Drives Cyclic Dynamics in a Field Vole Population.

Video & Audio

• Science vs Podcast: Sugar: How Bad Is It Really?
• Peter Attia Podcast: The Protein Debate: Optimal Intake, Limitations of the RDA, Whether High-Protein Intake Is Harmful, and How to Think About Processed Foods | David Allison, Ph.D.

Announcements

• Free Webinar Available on Demand October 28th, 2025 on Sarcopenia in Clinical Practice.