Obesity and Energetics Offerings

Featured

• RCT: Effects of a Diabetes Prevention Program on Type 2 Diabetes Risk Factors and Quality of Life Among Latino Youths with Prediabetes.
• E4orf1 Prevents Progression of Fatty Liver Disease in Mice on High Fat Diet.
• Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor Initiation and Hepatocellular Carcinoma Prognosis.
• Variability in Energy Expenditure Is Much Greater in Males Than Females.

Headline vs Study

• Study: Timing of Daily Calorie Loading Affects Appetite and Hunger Responses Without Changes in Energy Metabolism in Healthy Subjects with Obesity.
• Headlines: PlumX Metrics Show Mostly Reasonable Headlines!

Contrary or Null Findings

• RCT: Front-Loading Calories Early in the Day Reduces Hunger but Does Not Affect Weight Loss.
• RCT: Seven-Month Wintertime Supplementation of 1200 IU Vitamin D Has No Effect on Hand Grip Strength in Young, Physically Active Males.
• RCT: One-Week L-Arginine Supplementation Had No Effect on 200m Freestyle Swimming Time Trial in Moderately-Trained Male Swimmers.
• RCT: No Evidence of Brown Adipose Tissue Activation After 24 Weeks of Supervised Exercise Training in Young Sedentary Adults.
• RCT: No Differential Effect of DASH Diet vs. DASH Diet Plus Physical Activity in Older Patients with Type 2 Diabetes and High Blood Pressure.
• "These findings, surprisingly, indicate that during substantial weight gain, an increase in small adipocytes (suggesting hyperplastic expansion) is associated with impaired (not improved) metabolic health outcomes, specifically visceral and ectopic fat accumulation."
• "Contrary to the belief that adult adipocytes are relatively static, we show that adipocytes are very dynamic, relying on actin-driven mechanical forces to execute LD extrusion and intercellular LD transfer processes."
• Calorie Restriction Has No Effect on Bone Marrow Tumour Burden in a Vk*MYC Transplant Model of Multiple Myeloma [in Mice].

Basic

• Obesity Aggravated Hippocampal-Dependent Cognitive Impairment After Sleeve Gastrectomy in C57/BL6J Mice Via SIRT1/CREB/BDNF Pathway.
• Fish Oil Supplementation of Rats Fed a High Fat Diet During Pregnancy Improves Offspring Insulin Sensitivity.
• Malnourishment Affects Gene Expression Along the Length of the Small Intestine.
• Exercise and Metformin Intervention Prevents Lipotoxicity-Induced Hepatocyte Apoptosis by Alleviating Oxidative and ER Stress and Activating the AMPK/Nrf2/HO-1 Signaling Pathway in db/db Mice.
• Influences of the Interactions of Genetic Variations of Seven Core Circadian Clock Genes with Lifestyle Factors on Metabolic Parameters.
• Excess Dietary Zinc Drives a Cushing's-Like Syndrome in Ovariectomized Mice – Implications for Postmenopausal Obesity.

Scientific Rigor & Scholarly Dialogue

• Registering Incredulity.
• Strengthening Causal Inference from RCTs of Complex Interventions.

Clinical

• Scoping Review: Peripartum Care of Persons with Obesity.
• Effect of a Lifestyle Intervention on Cardiometabolic Health Among Emerging Adults.
• Effectiveness of a Nurse-Led mHealth App to Prevent Excessive Gestational Weight Gain Among Women with Overweight and Obesity.
• Fat-To-Muscle Ratio as a Predictor for Dyslipidaemia in Transitional-Age Youth.

Children and Adolescents

• Prospective Cohort Study: Association between Key Family and Individual Factors and Obesity Status Among Youth.
• "The First Step to Changing Something": Addressing Latinx Childhood Obesity through Photovoice.
• Metabolic Impact of Infant Formulas in Young Infants. An Outlook from the Urine Metabolome.
• Improving Nutrition in the First 1000 Days in the United States: A Federal Perspective.
• Developmental Pathways Linking Obesity Risk and Early Puberty: The Thrifty Phenotype and Fetal Overnutrition Hypotheses.

Surgery

• Meta-Analysis: New Insights on the Association between Socioeconomic Status and Weight Loss After Bariatric Surgery.
• Can Serum Basal Cortisol Values Predict Successful Operations for Bariatric Surgery Patients?
• Trends in Adolescent Bariatric Procedures: A 15-Year Analysis of the National Inpatient Survey.

Drugs

• RCT: 8-Week Intranasal Oxytocin Administration in Adults with Obesity: Rationale, Study Design, and Methods.
• Anti-Obesity Carbonic Anhydrase Inhibitors: Challenges and Opportunities.

Food & Diet

• RCT: The Effect of Steamed Potato-Wheat Bread Intake on Weight, Lipids, Glucose, and Urinary Na +/K +.
• Meta-Analysis: Effect of Flavonoid Intake on Circulating Levels of Adiponectin and Leptin.
• Association of Nut Consumption with CVD Risk Factors in Young to Middle-Aged Adults.
• "Increase in dietary choline or betaine intake were longitudinally related to improvements in cardiometabolic parameters".

Caloric and Dietary Restriction

• RCT: Effects of Inulin Supplementation on Inflammatory Biomarkers and Clinical Symptoms of Women with Obesity and Depression on a Calorie-Restricted Diet.
• RCT: Effect of Mediterranean Diet and Mediterranean Diet Plus Calorie Restriction on Cognition, Lifestyle, and Cardiometabolic Health.
• Obesity-Associated Anxiety Is Prevalent Among College Students and Alleviated by Calorie Restriction.

Exercise & Physical Activity

• Hypoxic High-Intensity Interval Training in Individuals with Overweight and Obesity.
• Late Afternoon Vigorous Exercise Increases Post-Meal but Not Overnight Hypoglycemia in Adults with Type 1 Diabetes Managed with Automated Insulin Delivery.
• Effects of Weight-Bearing Vs. Non-Weight-Bearing Endurance Exercise on Reducing Body Fat and Inflammatory Markers in Females with Obesity.
• Myokines in Adolescents with Obesity During Aerobic Exercise.

Economics & Sociology

• Systematic Review: Cost-Effectiveness of Continuous Glucose Monitoring Compared to Self-Monitoring of Blood Glucose in Type 1 Diabetes.
• Longitudinal Exposure to Neighborhood Poverty and Obesity Risk in Emerging Adulthood.

Epidemiology

• Long-Term Trends in Obesity Prevalence by Socio-Economic Group in Five European Countries and the USA.
• Body Composition of the Upper Limb Associated with Hypertension, Hypercholesterolemia, and Diabetes.

Psychology & Neuroscience

• Systematic Review: Effects of Mirror Exposure on Behaviour in Individuals with Obesity.
• Investigating Psychological Variables for Technologies Promoting Physical Activity.

Equity and Disparities

• Review: Care of Gender Diverse Youth with Obesity.
• Black New Yorkers with Type 2 Diabetes: Afro-Caribbean Immigrants Have Lower BMI and Lower Waist Circumference Than African Americans.

Stigma

• Cross-Sectional: Internalised Weight Stigma Mediates Relationships between Perceived Weight Stigma And Psychosocial Correlates In Individuals Seeking Bariatric Surgery.
• Cross-Sectional & Mixed Methods: “Thin and Muscular”.
• Fat Stigma and Body Objectification: A Text Analysis Approach Using Social Media Content.
• How Is Physicians' Implicit Prejudice Against People with Obesity or Mental Illness Moderated by Specialty and Experience?

Policy Related

• Cluster RCT: The Efficacy of a Multi-Strategy Choice Architecture Intervention on Improving the Nutritional Quality of High School Students' Lunch Purchases from Online Canteens (Click & Crunch High Schools).
• Review: Food Governance for Better Access to Sustainable Diets.
• Time Preference and Nutrition Label Use: Evidence from China.
• An Evaluation of the 'Bottom-Up' Implementation of the Active at School! Programme in Quebec, Canada.
• Case Study Implementing Nutrition and Sustainability Policy Into Government Food Procurement.
• Obesity Disparities and Evaluation of Public Policy Interventions at the Local Level.

Intergenerational Effects

• Meta-Analysis: Associations of Timing of Maternal Smoking Cessation Before and During Pregnancy with Childhood Overweight and Obesity.
• Longitudinal Characterization of Determinants Associated with Obesogenic Growth Patterns in Early Childhood.
• Prenatal Exposure to Polybrominated Diphenyl Ethers and BMI Z-Scores from 5 to 14 years.
• Protective Effect of Prenatal Social Support on the Intergenerational Transmission of Obesity in Low-Income Hispanic Families.
• Human Placental Lipid Content and Lipid Metabolic Enzyme Abundance in Obesity and Across Gestation.
• Associations between Maternal Metabolic Parameters During Pregnancy and Fetal and Child Growth Trajectories from 20 Weeks' Gestation to 5 years of Age.

Ecology, Evolution, & Energetics

• Scoping Review: Evaluating the Human Capacity of Carrying Loads Without Costs.
• Review: Neuroendocrine MicroRNAs Linked to Energy Homeostasis: Future Therapeutic Potential.
• Novel Host Unmasks Heritable Variation in Plant Preference Within an Insect Population.
• The Evolving View of Thermogenic Fat and Its Implications in Cancer and Metabolic Diseases.

Methods

• Personalized Energy Expenditure Estimation: Visual Sensing Approach with Deep Learning.
• Issues Related to the Assessment of Energy Balance During Short-Term Over-, Under- and Refeeding in Normal Weight Men.
• Anthropometric Equations to Predict Visceral Adipose Tissue in European and American Youth.

Commentary

• Sarcopenia and Sarcopenic Obesity in Chronic Kidney Disease: Update on Prevalence, Outcomes, Risk Factors and Nutrition Treatment.
• Food Texture Trumps Food Processing in the Regulation of Energy Intake.
• Looking for Real Plants in a Plant-Based Diet.
• Can the White House Fix Food?
• Locked Into the Wrong Debate About Obesity.
• Off-Label Drugs for Obesity.
• Treating Obesity to Prevent Diabetes.
• Adolescents with Anorexia Nervosa or Atypical Anorexia Nervosa with Premorbid Overweight/Obesity: What Should We Do About Their Weight Loss?

General

• Pilot Study: Effect of Cocoa (Theobroma cacao L.) on Platelet Function Testing Profiles in Patients with Coronary Artery Disease.
• That’s a Lot to Process! Pitfalls of Popular Path Models.
• Does Constructing a Belief Distribution Truly Reduce Overconfidence?
• No Evidence That Mandatory Open Data Policies Increase Error Correction.
• An Empirical Bayes Approach to Improving Population-Specific Genetic Association Estimation by Leveraging Cross-Population Data.
• Sex-Specific Endocrine Regulation of Seasonal Aggression in Siberian Hamsters.
• Body Image and Health-Related Behaviors Among Fitspirit Participants.
• On the Importance of the Dynamics of Humour and Comedy for Constructionism and Reflexivity in Social Science Research Methodology.

Video & Audio

• Greater male variability in energy expenditure (accompanies "Featured" article "Variability in Energy Expenditure Is Much Greater in Males Than Females."

Announcements

• "IU Bloomington and Indiana University-Purdue University-Indianapolis (IUPUI) received the only national award that honors individual institutions for being outstanding examples of universities committed to making diversity and inclusion a top priority across their campuses."
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Scientific Meeting: Causes of Obesity: Theories, Conjectures and Evidence.
• USDA Funds IU-Led Research Team to Develop Disease-Resistant Wheat.