Obesity and Energetics Offerings

Featured

• The Simplistic View of Obesity Management: A Curse in Disguise.
• The Overlooked Variable in Animal Studies: Why Diet Makes a Difference.
• Accelerating Animal Energetics: High Dive Costs in a Small Seabird Disrupt the Dynamic Body Acceleration - Energy Expenditure Relationship.(pdf)
• RCT: Sperm Count Is Increased by Diet-Induced Weight Loss and Maintained by Exercise or GLP-1 Analogue Treatment.
• Evaluating the Process to Develop the Dietary Guidelines for Americans, 2020–2025.

Headline vs Study

• Headline: Everyone Eats Three Extra Cheeseburgers a Day Than They Admit, Study Shows.
• Study: Estimates of Underreporting When Accounting for Allometric Scaling. Daily Cheeseburger Underreporting Not Described.

Contrary or Null Findings

• An Isoproteic Cocoa Butter-Based Ketogenic Diet Fails to Improve Glucose Homeostasis and Promote Weight Loss in Obese Mice.
• Meta-Analysis: No Major Differential Effects of Intermittent Fasting in Humans Compared to Caloric Restriction.
• Heat Acclimation in Females Does Not Limit Aerobic Exercise Training Outcomes.
• "...increased BMI is not positively associated with a greater odds of developing sarcoidosis." (pdf)
• BMI Is Not an Independent Factor Associated with Recovery Room Length of Stay for Patients Undergoing Outpatient Surgery.
• "The findings suggest that in diabetes patients increase in BMI alone does not lead to any alterations in their lipid profile."
• RCT: Resistance Training with or Without Nutritional Supplementation Showed No Influence on Muscle Thickness in Old Institutionalized Adults. A Secondary Analysis of the Vienna Active Ageing Study.
• "Highest quartile of percentage of energy intake from UPF [ultra-processed food] (PEI-UPF) was not significantly correlated with maternal GWG (p=0.215), infant QMR fat (p=0.816) and lean mass (p=0.423) or ADP fat (p=0.482) or fat-free mass (p=0.835)."

Basic

• Monochromatic Blue Light Not Green Light Exposure Is Associated with Continuous Light-Induced Hepatic Steatosis in High Fat Diet Fed-Mice Via Oxidative Stress.
• Deletion of GPR30 Drives the Activation of Mitochondrial Uncoupling Respiration to Induce Adipose Thermogenesis in Female Mice.
• IL-1R-IRAKM-Slc25a1 Signaling Axis Reprograms Lipogenesis in Adipocytes to Promote Diet-Induced Obesity in Mice.
• Calorie Restriction and Calorie Dilution Have Different Impacts on Body Fat, Metabolism, Behavior, and Hypothalamic Gene Expression.
• Differential Effects of Acute Versus Chronic Dietary Fructose Consumption on Metabolic Responses in FVB/N Mice.
• Adolescent Obesity Incurs Adult Skeletal Deficits in Murine Induced Obesity Model.

Scientific Rigor & Scholarly Dialogue

• Overview of Objective Measurement Technologies for Nutrition Research, Food-Related Consumer and Marketing Research.
• Adjusting for Collider Bias in Genetic Association Studies Using Instrumental Variable Methods.
• Letter: Common Errors and Pitfalls in Observational Studies Examining the Association of Medical Nutrition Therapy with Outcomes in Critically Ill Patients.
• Response: Reply to W. H. Hartl.
• Fixing Food Deserts: Promising or Trivial Effects?

Clinical

• RCT: Intervention Targeting Appetitive Traits on BMI Among Adults with Overweight or Obesity.
• Systematic Review: The Effectiveness of Weight Loss Programs for Low Back Pain.

Children and Adolescents

• Meta-Analysis: The Effectiveness of E-health Interventions for the Treatment of Overweight or Obesity in Children and Adolescents.
• Distinct Causal Effects of Body Fat Distribution on Cardiometabolic Traits Among Children.
• Systematic Review: Methods for the Economic Evaluation of Obesity Prevention Dietary Interventions in Children.
• Degree of Food Processing and Association with Overweight and Abdominal Obesity in Adolescents.

Surgery

• Development and Validation of an Artificial Intelligence-Based Model to Predict Gastroesophageal Reflux Disease After Sleeve Gastrectomy.
• Vertical Sleeve Gastrectomy Lowers SGLT2/Slc5a2 Expression in the Mouse Kidney.
• Effect of Meal Texture on Postprandial Glucose Excursions and Gut Hormones After Roux-En-Y Gastric Bypass and Sleeve Gastrectomy.
• Meta-Analysis: Bariatric Surgery and Cardiovascular Disease.

Drugs

• Impact of Antiseizure Medications on Appetite and Weight in Children.
• Cardiovascular Outcomes in Patients Initiating First-Line Treatment of Type 2 Diabetes with Sodium–Glucose Cotransporter-2 Inhibitors Versus Metformin: A Cohort Study.

Food & Diet

• Audio: When Climate Change Reaches Your Plate.
• Diverse Impact of N-Acetylcysteine or Alpha-Lipoic Acid Supplementation During High-Fat Diet Regime on Fatty Acid Transporters in Visceral and Subcutaneous Adipose Tissue.
• Antiobesity, Antihyperglycemic, and Antidepressive Potentiality of Rice Fermented Food Through Modulation of Intestinal Microbiota.
• Nicotinamide Reprograms Adipose Cellular Metabolism and Increases Mitochondrial Biogenesis to Ameliorate Obesity (in Mice).
• Association between Vitamin D and Adiponectin and Its Relationship with BMI.
• Meta-Analysis: Low Glycemic Index and Glycemic Load Diets in Adults with Excess Weight.

Caloric and Dietary Restriction

• Short-Term Moderate Caloric Restriction in a High-Fat Diet Alleviates Obesity Via AMPK/SIRT1 Signaling in White Adipocytes and Liver.
• Calorie Restriction and Calorie Dilution Have Different Impacts on Body Fat, Metabolism, Behavior, and Hypothalamic Gene Expression.
• RCT: Cardiometabolic Effects of Early Vs. Delayed Time-Restricted Eating Plus Caloric Restriction in Adults with Overweight and Obesity.

Exercise & Physical Activity

• Weights Can Be Weapons in Battle Against Obesity.
• Meta-Analysis: Factors That Moderate the Effect of Nitrate Ingestion on Exercise Performance in Adults.
• RCT: Influence of Diet on Acute Endocannabinoidome Mediator Levels Post Exercise in Active Women.
• RCT: Effects of Pre-Surgical Aerobic Dance-based Exercise on Lower Extremity in People with Morbid Obesity Awaiting Bariatric Surgery.
• Duration of an Acute Moderate-Intensity Exercise Session Affects Approach Bias Toward High-Calorie Food Among Individuals with Obesity.

Economics & Sociology

• Socioeconomic Status and Eating Disorder Prevalence: At the Intersections of Gender Identity, Sexual Orientation, and Race/ethnicity.
• Systematic Review: Cultural Factors Related to Childhood and Adolescent Obesity in Mexico.
• Socioeconomic Differences in the Association between Maternal Age and Maternal Obesity: A Register-Based Study of 707,728 Women in Finland.
• Scoping Review: Family Socioeconomic Status and Childhood Adiposity in Europe.

Epidemiology

• Hypertension Modifies the Associations of BMI and Waist Circumference with All-Cause Mortality Among Older Chinese: A Retrospective Cohort Study.
• Obesity and Accelerated Epigenetic Aging in a High-Risk Cohort of Children.
• Temporal Relationship Among Adiposity, Gut Microbiota, and Insulin Resistance in a Longitudinal Human Cohort.

Psychology & Neuroscience

• Association of Food Insecurity and Food Addiction Symptoms: A Secondary Analysis of Two Samples of Low-Income Female Adults.
• RCT: Physical and Mental Health Outcomes of an Integrated Cognitive Behavioural and Weight Management Therapy for People with an Eating Disorder Characterized by Binge Eating and a High BMI.
• Long-Term Priming of Hypothalamic Microglia Is Associated with Energy Balance Disturbances Under Diet-Induced Obesity.

Equity and Disparities

• Neighborhood Deprivation and Obesity: Sex-Specific Effects of Cross-Sectional, Cumulative and Residential Trajectory Indicators.
• Anti-Obesity Medication Prescriptions by Race/ethnicity and Use of an Interpreter in a Pediatric Weight Management Clinic.

Stigma

• Book Chapter: Bias, Stigma, and Social Consequences of Obesity.
• Weight Stigma in Children and Adolescents: Recommendations for Practice and Policy.

Policy Related

• Use of Food and Nutrition Labels Among Urban Mongolian Supermarket Shoppers: Implications for Food Labeling Policy and Practice.
• Perspective: Overcoming Congressional Inertia on Obesity Requires Better Literacy in Obesity Science.

Intergenerational Effects

• The Influence of Parental Body Composition and Lifestyle on Offspring Growth Trajectories.
• Nutrition During Pregnancy and Lactation: New Evidence for the Vertical Transmission of Extra Virgin Olive Oil Phenolic Compounds in Rats.
• The Mediating Effect of DNA Methylation in the Association between Maternal Sleep During Pregnancy and Offspring Adiposity Status: A Prospective Cohort Study.

Ecology, Evolution, & Energetics

• Complications with Body-Size Correction in Comparative Biology: Possible Solutions and an Appeal for New Approaches.
• Physiological Effects of Food Availability Times in Higher Vertebrates.

Methods

• Systematic Review: Methods Used to Assess and Report Dietary Patterns.
• Validating Dietary Assessment Tools with Energy Expenditure Measurement Methods: Is This Accurate?

Mathematical and Quantitative

• Leptin Effect’s on Glucose and Insulin Kinetics: A Mathematical Model.
• The Impact of Media Coverage on Obesity.

Commentary

• Intro to Lipids & Lipoproteins: Why There Is No ‘Bad’ or ‘Good’ Cholesterol.
• Audio: How Restaurant Menus Mirror Our Warming Ocean.
• Do You Love or Loathe Coffee? Your Genes May Be to Blame.
• Food Cues in the Eat-More Food Environment.
• Infant and Child Formula Shortages: Now Is the Time to Prevent Recurrences.
• Tirzepatide Pricing Comes in Similar to Semaglutide.
• Podcast: "Anti-Aging" Drugs — NAD+, Metformin, & Rapamycin.
• Alzheimer's Disease: The Inevitable Presence of Absence (Does Metformin Have a Role in Alzheimer's Disease?).(pdf)

General

• Dissertation: A Toxicogenomic Analysis of the Hepatic Response to Triclosan.
• Insights from a High-Fat Diet Fed Mouse Model with a Humanized Liver.
• Musings on Mentoring: Teach Your “Children” Well.
• Fluid Balance Is Unlikely Modified by the Menstrual Cycle When Ad Libitum Drinking Is Permitted During Physical Work in the Heat.
• Urban-Adapted Mammal Species Have More Known Pathogens.
• Your Brain Operates at the Edge of Chaos, but That's Not a Bad Thing.
• Effects of Prior Exposure to Conflicting Health Information on Responses to Subsequent Unrelated Health Messages: Results from a Population-Based Longitudinal Experiment.
• Rising Temperatures Erode Human Sleep Globally.

Announcements

• Regenstrief and Indiana University Study Explores Eating, Drinking, and Physical Activity Among Middle Aged Women Living with Obesity and Urban Poverty.
• Applications Open: 2022 Mathematical Sciences in Obesity Research Short Course.
• Applications Open: Strengthening Causal Inference in Behavioral Obesity Research Short Course 2022.

Featured

• Association between a Policy to Subsidize Supermarkets in Underserved Areas and Childhood Obesity Risk.
• Taking a Hard Look at the Empirical Evidence for Popular Community-Based Interventions in Obesity.
• A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity.
• Expression of Obesity-Related Genes in Human Spermatozoa Affects the Outcomes of Reproductive Treatments.

Headline vs Study

• Headline: Poor Sleep Prevents Dieters from Keeping the Weight Off.
• Press-Release: Poor Sleep May Undermine People’s Attempts to Keep Weight Off.
• Meeting Abstract PO3.26: From press release: "Despite the important findings, the authors note that the study is observational and cannot prove that poor sleep causes weight changes."

Contrary or Null Findings

• RCT: "green exercise does not elicit greater reductions in anxiety than urban exercise."
• "Longitudinal Actor-Partner Interdependence Models results showed no indication of selection or socialization...[when] Examining food intake similarities in Adolescent best friend dyads using Longitudinal Actor-Partner Interdependence Models."
• Meta-Analysis: "Compared to continuous energy restriction (CER), IER showed no significant long-term differences in anthropometric, cardiometabolic, inflammatory, or appetite outcomes in included studies."
• RCT: "Resveratrol supplementation had no effect on hepatic steatosis and cardiovascular indices."
• RCT: "The PLAYCE PAWS mHealth intervention did not significantly affect dog-facilitated physical activity in children."
• RCT: "...a single session of eight 4-minute cycles of intermittent hypoxia did not increase serum EPO levels in older individuals."
• RCT: "...a single intramuscular injection of triamcinolone acetonide was sufficient to accelerate erythropoiesis and increase Hbmass, but did not translate into improved aerobic exercise performance..."
• RCT: "The MISAME-III trial did not provide evidence that fortified BEP supplementation is efficacious in reducing SGA [small for gestational age] prevalence."

Basic

• Cyclooxygenase-2 in Adipose Tissue Macrophages Limits Adipose Tissue Dysfunction in Obese Mice.
• Di-(2-Ethylhexyl) Phthalate Substitutes Accelerate Human Adipogenesis Through PPARγ Activation and Cause Oxidative Stress and Impaired Metabolic Homeostasis in Mature Adipocytes.
• Angiotensin-(1-7) Mas Receptors Localized to Proopiomelanocortin Neurons Tonically Regulate Insulin Sensitivity.
• Obesity Differentially Effects Visceral Vs. Subcutaneous Adipose Arteries: Role of Shear Activated Kir2.1 and Alterations to the Glycocalyx in Mediating Endothelial Dysfunction.
• Obesity Exacerbates Lipid Nephrotoxicity and Renal Injury in a Model of Ovarian Hormone Deficiency.
• Spexin Modulates Molecular Thermogenic Profile of Adipose Tissue and Thermoregulatory Behaviors in Female C57BL/6 Mice.
• Differing Impact of Phosphoglycerate Mutase 1-Deficiency on Brown and White Adipose Tissue.

Scientific Rigor & Scholarly Dialogue

• Article: Effect of School-Based Interventions on Body Composition of Grade-4 Children from Lower Socioeconomic Communities in Gqeberha, South Africa.
• Corrigendum: "The two groups met, collegially discussed the issue, and decided to jointly publish a corrigendum and re-label the study from a [cluster randomized controlled trial] to a quasi-experimental study to uphold the integrity of the scientific record".
• Commentary: "Through collegial dialogue, the investigators reached a shared understanding with experts from the IU School of Public Health and jointly issued an correction this week to ensure integrity for the scientific record."
• Retraction: Kale (Brassica oleracea var. sabellica) as Miracle Food with Special Reference to Therapeutic and Nutraceuticals Perspective.
• Retraction Watch: Kale ‘Miracle Food’ Paper Retracted for Being ‘Word Salad’.

Clinical

• Soluble Receptor for Advanced Glycation End Products (sRAGE) Isoforms Predict Changes in Resting Energy Expenditure in Adults with Obesity During Weight Loss.
• Associations between Adult Triceps Skinfold Thickness and All-Cause, Cardiovascular and Cerebrovascular Mortality in NHANES 1999–2010: A Retrospective National Study.
• Retrospective Analysis of the Impact of Severe Obesity on Kidney Transplant Outcomes.

Children and Adolescents

• Behavioral, Cognitive, and Socioemotional Pathways from Early Childhood Adversity to BMI: Evidence from Two Prospective, Longitudinal Studies.
• The Impact of Obesity Assessed by Different Criteria on the Metabolic Parameters in Children and Adolescents in Georgia.
• Detection of Visceral Obesity in Children and Adolescents Based on Body Composition Analysis.
• Is Maternal Autonomy Associated with Child Nutritional Status? Evidence from a Cross-Sectional Study in India.

Surgery

• Anxiety Predicts Reduced Weight Loss 30 Months After Bariatric Surgery.
• Assessment of the Body Composition and the Loss of Fat-Free Mass Through Bioelectric Impedance Analysis in Patients Who Underwent Open Gastric Bypass.
• Factors Associated with Increased Risk for Pulmonary Embolism After Metabolic and Bariatric Surgery: Analysis of Nearly One Million Patients.
• Effect of Bariatric Surgery on Albuminuria in Non-Diabetic Non-Hypertensive Patients with Severe Obesity.

Drugs

• FDA Approves “An Important Advance,” Tirzepatide.
• Assessment of Redox State and Biochemical Parameters of Salivary Glands in Rats Treated with Anti-Obesity Drug Sibutramine Hydrochloride.
• Omega-3 Phospholipids and Obesity-Associated NAFLD: Potential Mechanisms and Therapeutic Perspectives.
• Transdermal Photothermal-Pharmacotherapy to Remodel Adipose Tissue for Obesity and Metabolic Disorders.
• Perceptions of Obesity Pharmacotherapy by Nurse Practitioners.

Food & Diet

• Dietary and Lifestyle Indices for Hyperinsulinemia with the Risk of Obesity Phenotypes: A Prospective Cohort Study Among Iranian Adult Population.
• Review: Potential Role of Selenium in Alleviating Obesity-Related Iron Dyshomeostasis.
• Quinoa Reduces High-Fat Diet-Induced Obesity in Mice Via Potential Microbiota-Gut-Brain-Liver Interaction Mechanisms.

Caloric and Dietary Restriction

• Circadian Alignment of Early Onset Caloric Restriction Promotes Longevity in Male C57BL/6J Mice.
• Estimating Heterogeneity of Physical Function Treatment Response to Caloric Restriction Among Older Adults with Obesity.
• The Combination of Intermittent Caloric Restriction and Moderate-Intensity Interval Training in Decreasing Blood Glucose and CRP Levels with a High Glycemic Index Diet.

Exercise & Physical Activity

• Unbiased Proteomics, Histochemistry, and Mitochondrial DNA Copy Number Reveal Better Mitochondrial Health in Muscle of High-Functioning Octogenarians.
• Meta-Analysis: Where Does the Time Go? Displacement of Device-Measured Sedentary Time in Effective Sedentary Behaviour Interventions.
• Physical Literacy Predicts the Physical Activity and Sedentary Behaviours of Youth.
• Introduction to the Special Section: Approaches to Understanding and Increasing Physical Activity.

Economics & Sociology

• Using Geographically Weighted Models to Explore Obesity Prevalence Association with Air Temperature, Socioeconomic Factors, and Unhealthy Behavior in the USA.
• Neighborhood Greenspace and Socioeconomic Risk are Associated with Diabetes Risk at the Sub-Neighborhood Scale.
• Exploring How Socioeconomic Status Affects Neighbourhood Environments’ Effects on Obesity Risks.
• Growing Taller Unequally? Adult Height and Socioeconomic Status in Spain.

Epidemiology

• Systematic Review: The Influence of Green Space on Obesity in China.
• Effects of Age and Gender on Body Composition Indices as Predictors of Mortality in Middle-Aged and Old People.
• Steady Increase of Obesity Prevalence in Austria: Analysis of Three Representative Cross-Sectional National Health Interview Surveys from 2006 to 2019.
• Food Insecurity Among Disabled Adults.
• A 2022 Update on the Epidemiology of Obesity and a Call to Action: As Its Twin COVID-19 Pandemic Appears to Be Receding, the Obesity and Dysmetabolism Pandemic Continues to Rage On.
• Associations of Physical Activity with Sarcopenia and Sarcopenic Obesity in Middle-Aged and Older Adults: The Louisiana Osteoporosis Study.

Psychology & Neuroscience

• Waist Circumference and Its Association with Premenstrual Food Craving: The PHASE Longitudinal Study.
• Hypothalamic AMPK as a Possible Target for Energy Balance-Related Diseases.
• Day/Night Changes in the Dorsomedial Hypothalamus Firing Responses to Ghrelin are Modulated by High-Fat Diet.
• Impaired Brain Satiety Responses After Weight Loss in Children with Obesity.
• Exploring the Association between Self-Compassion, Mindfulness and Mindful Eating with Eating Behaviours Amongst Patients with Obesity.

Equity and Disparities

• Changes in the Association between Overweight and Depression Across Three Major Ethnic Groups, 2005–2018.
• The Prevalence of Overweight Status Among Early Adolescents from Private Schools in Indonesia: Sex-Specific Patterns Determined by School Urbanization Level.

Stigma

• Are Dietitians with Obesity Perceived as Competent and Warm? Applying the Stereotype Content Model to Weight Stigma in Brazil.
• Investigating the Disease Is the Key to the Obesity Stigma.

Policy Related

• Association between a Policy to Subsidize Supermarkets in Underserved Areas and Childhood Obesity Risk.
• Adults’ Exposure to Unhealthy Food and Beverage Marketing: A Multi-Country Study in Australia, Canada, Mexico, United Kingdom, and United States.
• RCT: Do Sugar Warning Labels Influence Parents’ Selection of a Labeled Snack for Their Children? RCT in a Virtual Convenience Store.

Intergenerational Effects

• Implementation of a Healthy Diet to Lactating Rats Attenuates the Early Detrimental Programming Effects in the Offspring Born to Obese Dams. Putative Relationship with Milk Hormone Levels.
• Parental Obesity Alters Offspring Blood Pressure Regulation and Cardiovascular Responses to Stress: Role of P2X7R and Sex Differences.
• Maternal Adiposity Inversely Associates with Physical Activity in 2-Year-Old Girls.

Ecology, Evolution, & Energetics

• Long-Term Obesogenic Diet Leads to Metabolic Phenotypes Which are Not Exacerbated by Catch-Up Growth in Zebrafish.
• Olfaction in the Context of Obesity and Diabetes: Insights from Animal Models to Humans.

Methods

• Natural Experiments: A Nobel Prize Awarded Research Design for Strengthening Causal Inference on Global Health Challenges. (pdf)
• Systematic Review: Estimates of Resting Energy Expenditure and Total Energy Expenditure Using Predictive Equations in Adults with Overweight and Obesity.
• Challenges in Obtaining Accurate Anthropometric Measures for Adults with Severe Obesity: A Community-Based Study.
• Penn State Equation Versus Indirect Calorimetry for Nutritional Assessment in Patients with Traumatic Brain Injury.

Mathematical and Quantitative

• Dissertation: A Comprehensive Dynamic Model of the Adipocyte.
• Modeling Analysis of the Relationship between Adolescent Aerobic Exercise and Obesity Reduction Based on Deep Learning.
• Mathematical Modeling of Gastrointestinal Starch Digestion-Blood Glucose-Insulin Interactions.

Commentary

• Sex, Muscles and Metabolism.
• CRISPR tool reverse one big consequence of "teenage" drinking in rats.
• ECO2022: Bias Against Persons HCPs are “Caring” For.
• When Does Obesity Care Bring a Longer Life?
• Daunting Medical Words – Like Obesity.
• More Evidence That Good Sleep Helps with Obesity.
• Opportunities and Challenges of Mobile Health Tools to Promote Health Behaviors.
• Dubious Diet Science: On the Perils of Ultraprocessed Food for Thought.

General

• Could We Make Ageing a Thing of the Past?
• Distribution of Females Influences the Evolution of Testes Size in Australian Rodents.
• Conformist Social Learning Leads to Self-Organised Prevention Against Adverse Bias in Risky Decision Making.
• Deadly Venom from Spiders and Snakes May Also Cure What Ails You.
• Researchers Should Be Assessed on Quality Not Quantity: Here’s How.
• Video: Nobel Conversations: How Will Machine Learning Impact Economics?
• Meta-Analysis: Face-To-Face Medication Adherence Interventions for Patients with Long Term Health Conditions.
• New Instructions to Authors Emphasize Open Science, Transparency, Full Reporting of Sociodemographic Characteristics of the Sample, and Avoidance of Piecemeal Publication.

Announcements

• NFL Alumni Wins Major Award for Obesity Awareness Campaign.
• 2022 National Workshop on Data Science Education.
• Applications Open: 2022 Mathematical Sciences in Obesity Research Short Course.
• Applications Open: Strengthening Causal Inference in Behavioral Obesity Research Short Course 2022. Priority Application by June 17.

Featured

• The Energy Balance Model of Obesity - Beyond Calories In, Calories Out.
• Circadian Alignment of Early Onset Caloric Restriction Promotes Longevity in Male C57BL/6J Mice.
• Meta-analysis: Red Meat Consumption and Risk Factors for Type 2 Diabetes.
• RCT: People's Intended Serving Behaviour at Social Vs. Non-Social Meals.

Headline vs Study

• Headline: Better School Lunches Blunt U.S. Kids' Weight Gain.
• Study: Associations between the Free or Reduced-Price National School Lunch Program and BMI-Related Outcome Before Versus After Implementation of the Healthy, Hunger-Free Kids Act of 2010. Causation Not Established.
• Headline: Study Highlights Need for Tailored Weight Loss Plans to Treat Obesity.
• Meeting Abstract: Survey of Obesity-Related Complications and Healthcare Resource Use in Six European Countries. Need for Tailoring Neither Assessed nor Defined.

Contrary or Null Findings

• RCT: No Significant Effects of Cognitively Engaging Physical Activity on Preschool Children's Cognitive Outcomes.
• "In our sample of overweight and obese adults, no beneficial effect of adding exercise to an energy-restricted diet was found in terms of HRQOL and Depression."
• No Evidence That Long Runs of Homozygosity Tend to Harbor Risk Variants for Polygenic Obesity in Labrador Retriever Dogs.
• "Evidence of clinically meaningful differences in growth or biochemical measures of nutrition for children with vegetarian diet was not found."
• Exercise Training Does Not Affect Heat Tolerance in Chinook Salmon (Oncorhynchus tshawytscha).
• Gestational Purple Grape Juice Consumption Does Not Change Fetal Ductus Arteriosus Constriction in Wistar Rats.
• RCT: Caffeine ... Does Not Modify Substrate Oxidation During 1 H of Self-Paced Cycling.
• RCT: Sodium Citrate Supplementation...has No Influence on HRV Responsiveness in Endurance- Trained Men.

Basic

• Whole-Genome Shotgun Metagenomic Sequencing Reveals Distinct Gut Microbiome Signatures of Obese Cats.
• Metformin Combats Obesity by Targeting FTO in an M6A-YTHDF2-Dependent Manner.
• HIF-2α Preserves Mitochondrial Activity and Glucose Sensing in Compensating Beta Cells in Obesity.
• Aerobic Exercise Improves Adipogenesis in Diet-Induced Obese Mice Via the LncSRA/p38/JNK/PPARγ Pathway.
• The Effect of α-Lipoic Acid on Oxidative Stress in Adipose Tissue of Rats with Obesity-Induced Insulin Resistance.

Scientific Rigor & Scholarly Dialogue

• Why are We Basing Food Policy on Black Box Data?
• Article: Feasibility, Safety, and Beneficial Effects of MCT-Based Ketogenic Diet for Breast Cancer Treatment: A Randomized Controlled Trial Study.
• Letter: Critical Remarks to the Article by Khodabakhshi and Colleagues Reporting Results from a Randomized Study on Ketogenic Diet.
• Critics Challenge Data Showing Key Lipids Can Curb Inflammation.

Clinical

• Proposal of an Obesity Classification Based on Weight History: An Official Document by the Brazilian Society of Endocrinology and Metabolism (SBEM) and the Brazilian Society for the Study of Obesity and Metabolic Syndrome (ABESO).
• Induction of Labour at 39 Weeks Versus Expectant Management in Low-Risk Women with Obesity.

Children and Adolescents

• Association between Postterm Pregnancy and Adverse Growth Outcomes in Preschool-Aged Children.
• Impaired Brain Satiety Responses After Weight Loss in Children with Obesity.
• ECO2022: A Massive Global Survey of Teen Obesity.
• Birth Anthropometry Predicts Neonatal and Infant Mortality in Rural Bangladesh: A Focus on Circumferential Measurements.
• Role of Diet Quality in the Association between Excess Weight and Psychosocial Problems in a Large Sample of Children in Spain.

Surgery

• Remission of Diabetes and Cardiometabolic Risk in Patients After 5 Years of Bariatric Surgery: A Case-Control Study.
• Robotic Vs. Laparoscopic Metabolic and Bariatric Surgery, Outcomes over 5 Years in Nearly 800,000 Patients.
• Five-Year Changes in Weight and Diabetes Status After Bariatric Surgery for Craniopharyngioma-Related Hypothalamic Obesity: A Case-Control Study.
• RCT: Intraperitoneal Instillation of Local Anesthetic (IPILA) in Bariatric Surgery and the Effect on Post-Operative Pain Scores.

Drugs

• Apixaban and Rivaroxaban Use for Atrial Fibrillation in Patients with Obesity and BMI ≥50 Kg/m2.
• Clinical Review of Subcutaneous Semaglutide for Obesity.
• Long-Acting Amylin Analogues for the Management of Obesity.
• Association of Glucagon-Like Peptide-1 Receptor Agonist Use with Risk of Gallbladder and Biliary Diseases.
• RCT: Phentermine/Topiramate for the Treatment of Adolescent Obesity.

Food & Diet

• Meta-Analysis: Association between Adherence to the Mediterranean Diet and Risk of Type 2 Diabetes.
• β-Hydroxybutyrate Suppresses Colorectal Cancer.
• Identification of Sex and Aging Differences in C57BL/6-NClr Mice on the Ketogenic Diet.
• Effects of Siraitia grosvenorii Extracts on High Fat Diet-Induced Obese Mice: A Comparison with Artificial Sweetener Aspartame.
• RCT: Effects of Nigella sativa Supplementation on Blood Concentration and MRNA Expression of TNF-α, PPAR-γ and Adiponectin, as Major Adipogenesis-Related Markers, in Women with Overweight and Obesity.
• The Association between Dietary Polyphenol Intake and Cardiometabolic Factors in Women with Overweight and Obesity: A Cross-Sectional Study.
• Intuitive Eating and Biomarkers Related to Cardiovascular Disease in Older Adults.
• The Effect of a High-Polyphenol Mediterranean Diet (Green-MED) Combined with Physical Activity on Age-Related Brain Atrophy.
• Systematic Review: The Effects of Zinc and Selenium Supplementation on Body Composition and Thyroid Function in Individuals with Overweight or Obesity.
• Plasmalogens Eliminate Aging-Associated Synaptic Defects and Microglia-Mediated Neuroinflammation in Mice.

Caloric and Dietary Restriction

• Time-Restricted Feeding Improved Vascular Endothelial Function in a High-Fat Diet-Induced Obesity Rat Model.
• Distinct and Additive Effects of Calorie Restriction and Rapamycin in Aging Skeletal Muscle.
• Individual Evaluation of Aging- and Caloric Restriction-Related Changes to Distinct Multimeric Complexes of Circulating Adiponectin by Immunoblotting.
• Effects of Dietary Energy Density and Supplemental Rumen Undegradable Protein on Intake, Viscera, and Carcass Composition of Lambs Recovering from Nutritional Restriction.
• Higher Protein Intake During Caloric Restriction Improves Diet Quality and Attenuates Loss of Lean Body Mass.
• Effects of Caloric Restriction on the Gut Microbiome are Linked with Immune Senescence.

Exercise & Physical Activity

• Relative Fat Mass Assessment Estimates Changes in Adiposity Among Female Older Adults with Obesity After a 12-Month Exercise and Diet Intervention.
• Consensus Statement: Asia-Pacific Consensus Statement on Integrated 24-Hour Activity Guidelines for Children and Adolescents.
• Effect of Severe Compared with Moderate Energy Restriction on Physical Activity Among Postmenopausal Female Adults with Obesity.
• RCT: Effects of Reduced Sedentary Time on Cardiometabolic Health in Adults with Metabolic Syndrome.

Economics & Sociology

• Public Health in the Making: Dietary Innovators and Their On-The-Job Sociology.
• Dissertation: Salient Beliefs of Individuals with Obesity: A Qualitative Study Based on the Theory of Planned Behavior.
• Healthcare Costs and Hospitalizations in US Patients with Type 2 Diabetes and Cardiovascular Disease: A Retrospective Database Study (OFFSET).

Epidemiology

• Elements Behind Sedentary Lifestyles and Unhealthy Eating Habits in Individuals with Severe Obesity.
• Association of BMI and Abdominal Obesity with the Risk of Airflow Obstruction: National Health and Nutrition Examination Survey (NHANES) 2007-2012.
• Body Composition in Amyotrophic Lateral Sclerosis Subjects and Its Effect on Disease Progression and Survival.
• Prevalence of Gestational Diabetes Increases by Almost 40% During COVID-19 Pandemic.
• Dose–response Association of the Dietary Inflammatory Potential with All-Cause and Cause-Specific Mortality.

Psychology & Neuroscience

• Altered Neural Correlates of Episodic Memory for Food and Non-Food Cues in Females with Overweight/Obesity.
• Commentary: Maternal Proinflammatory Processes and Fetal Neurodevelopment: Integrating Clinical and Preclinical Research Approaches and Identifying Knowledge Gaps That Warrant Future Collaboration.
• Need of Nutritional Assessment and Monitoring in a Population with Acquired Brain Injury: An Analytical Cross-Sectional Study.
• Systematic review and meta-analysis: Effects of Dietary Restriction on Cognitive Function.

Equity and Disparities

• Diabetes Screening by Race and Ethnicity in the United States: Equivalent BMI and Age Thresholds.
• What Factors Drive Gender Differences in the BMI? Evidence from Turkish Adults.
• Disparity in Obesity and Hypertension Risks Observed between Pacific Islander and Asian American Health Fair Attendees in Los Angeles, 2011–2019.

Stigma

• Development of a Cognitive-Behavioral Intervention for Internalized Weight Stigma.
• Stepping Up to Shut Down Harmful Health Stigma.
• Weight Stigma Among Heterosexual and Sexual Minority Individuals: Dating and Hiring Preferences.
• Concept Mapping of Weight Bias Among Canadian Young Adults.
• Stigma Toward Bariatric Surgery in the Netherlands, France, and the United Kingdom: Protocol for a Cross-Cultural Mixed Methods Study.

Policy Related

• The Impact of Taxing Sugar-Sweetened Beverages in México: A Censored QUAI Demand System Approach.
• Obesity: No European Country Is on Track to Halt Rising Levels by 2025, WHO Warns.
• Using Systems Science for Strategic Planning of Obesity Prevention and Treatment: The Roundtable on Obesity Solutions Experience.

Intergenerational Effects

• Impact of Earlier Gestational Diabetes Screening for Pregnant People with Obesity on Maternal and Perinatal Outcomes.
• RCT: Relationship between Chrono-Nutrition, Sleep and Glycemic Control in Women with Gestational Diabetes.
• The Relationship between Obesity and Pre-Eclampsia: Incidental Risks and Identification of Potential Biomarkers for Pre-Eclampsia.
• Can Adult Polygenic Scores Improve Prediction of BMI in Childhood?

Ecology, Evolution, & Energetics

• Systematic Review: Weight Loss and Fat Metabolism During Multi-Day High-Altitude Sojourns: A Hypothesis Based on Adipocyte Signaling.
• Obesity: An Evolutionary Context.
• Climate Change, Urbanisation, and Their Impact on Increased Occurrence of Cardiometabolic Syndrome.

Methods

• RCT: Amino Acid Nitrogen Isotope Ratios Respond to Fish and Meat Intake in a 12-Week Inpatient Feeding Study of Adult Men.
• Construction of Regression Equation for Maximum Oxygen Uptake Recognition of Respiration and Heart Rate in Exercise Training.
• Concurrent Outcomes from Multiple Approaches of Epistasis Analysis for Human BMI Associated Loci Provide Insights Into Obesity Biology.
• The Food Recognition Benchmark: Using Deep Learning to Recognize Food in Images.

Commentary

• Audio: NPR - TASTE BUDDIES: Y U Salty?
• The Wonky Overlap in Federal Food Regulation.
• ECO2022: Obesity Hype, Hope, and Progress.
• Communicating Your Findings Through Graphical Abstracts.
• For Mice, Fasting at the Right Time Extended Lifespans — but Can It Work for Humans?
• With New Diabetes Drug Data, Eli Lilly Is Taking Aim at Obesity.
• Using Systems Science for Strategic Planning of Obesity Prevention and Treatment: The Roundtable on Obesity Solutions Experience.
• Are Nitrates the Next Big Thing for Athletic Performance?

General

• Podcast: Centenarians, Metformin, and Longevity with Nir Barzilai, M.D.
• GRATIFOOD.
• I Was Thinking to Help but Then I Changed My Mind! The Influence of Injunctive and Descriptive Norms on the Donation Intention-Behavior Link.
• Does cognitive control affect successful "sandbagging" of concussion symptoms?
• To Tailor or Not to Tailor: An Investigation of Narrative Tailoring for Health Communication.
• It's Not a Lie If You Believe the Norm Does Not Apply: Conditional Norm-Following and Belief Distortion.
• The Evidence Does Not Support Long-Term Oxygenation as a Functional Explanation for the Evolution of Yawning.
• RandoMice, a Novel, User-Friendly Randomization Tool in Animal Research.
• Thesis: Predictors of Perceived Scarcity: The Impact of Demographic Factors, Objective Socioeconomic Status, and Subjective Social Status.

Video & Audio

• Video: NIH Obesity Research Task Force - Moving Beyond BMI: Exploring the Heterogeneity of Obesity.

Announcements

• Indiana University School of Public Health-Bloomington Faculty Member to Be Named President of National Lipid Association.
• ASN Foundation Announces More Registration Award & Grant Opportunities to Increase Accessibility of Nutrition 2022 Live Online.
• Applications Open: 2022 Mathematical Sciences in Obesity Research Short Course. Priority Application by May 17.
• Applications Open: 2022 Strengthening Causal Inference in Behavioral Obesity Research Short Course. Priority Application by June 17.

Featured

• RCT: Effects of a Laughter Program on Body Weight and Mental Health Among Japanese People with Metabolic Syndrome Risk Factors.
• Intraclass Correlation Coefficients for Weight Loss Cluster Randomized Trials in Primary Care: The PROPEL Trial.
• Capsaicin Directly Promotes Adipocyte Browning in the Chemical Compound-Induced Brown Adipocytes Converted from Human Dermal Fibroblasts.
• Time to Revisit the Passive Overconsumption Hypothesis? Humans Show Sensitivity to Calories in Energy-Rich Meals.

Headline vs Study

• Headline: Walking Just 10 Minutes a Day May Lead to a Longer Life.
• Study: Estimated Number of Deaths Prevented Through Increased Physical Activity Among US Adults - "the observational study design limits the direct determination of causality."
• Critique: Does Walking 10 Minutes Per Day Extend Your Life? (Hint: No.).

Contrary or Null Findings

• RCT: "Our CBT-based intervention for parents of children with obesity was not superior in reducing BMI z-score vs. our PEP-based intervention."
• RCT: No Effect of Isolated Anthocyanins from Bilberry Fruit and Black Rice on LDL Cholesterol or Other Biomarkers of Cardiovascular Disease in Adults with Elevated Cholesterol.
• RCT: High Dietary Nucleotide Consumption for One Week Increases Circulating Uric Acid Concentrations but Does Not Compromise Metabolic Health.
• RCT: Brazil Nut Supplementation Does Not Affect Trimethylamine-N-Oxide Plasma Levels in Patients with Coronary Artery Disease.
• BMI Does Not Impact Survival in COVID-19 Patients Requiring Veno-Venous Extracorporeal Membrane Oxygenation.
• Aflatoxin M1 in Milk Does Not Contribute [is Not Associated With] Substantially to Global Liver Cancer Incidence.
• No Effect of Chronotype on Hunger or Snack Consumption During a Night Shift with Acute Sleep Deprivation.
• Prior Arm Crank Exercise Has No Effect on Postprandial Lipaemia in Non-Disabled Adults.

Basic

• Strength Training Alters the Tissue Fatty Acids Profile and Slightly Improves the Thermogenic Pathway in the Adipose Tissue of Obese Mice.
• YAP-Dependent Wnt5a Induction in Hypertrophic Adipocytes Restrains Adiposity.
• Obesity Modulates the Immune Macroenvironment Associated with Breast Cancer Development.
• Subcutaneous Administration of a Nitric Oxide-Releasing Nanomatrix Gel Ameliorates Obesity and Insulin Resistance in High-Fat Diet-Induced Obese Mice.
• Monitoring of Inflammation Using Novel Biosensor Mouse Model Reveals Tissue- and Sex-Specific Responses to Western Diet.

Scientific Rigor & Scholarly Dialogue

• A Viral Twitter Thread Reawakens the Dark History of Anthropology.
• Article: Adjustment for Energy Intake in Nutritional Research: A Causal Inference Perspective.
• Letter: Re: Adjustment for Energy Intake in Nutritional Research: A Causal Inference Perspective.

Clinical

• Sex-Associated Differences between BMI and SARS-CoV-2 Antibody Titers Following the BNT162b2 Vaccine.
• Systematic Review: The Influence of Bariatric (Metabolic) Surgery on Blood Polyunsaturated Fatty Acids.
• Enriched Marine Oil Supplement Increases Specific Plasma Specialized Pro-Resolving Mediators in Adults with Obesity.

Children and Adolescents

• Age at Adiposity Rebound and the Relevance for Obesity.
• Systematic Review: Sleep Timing and Health Indicators in Children and Adolescents.
• Changes in Body Size Phenotypes from Childhood to Adulthood and the Associated Cardiometabolic Outcomes.
• Association of Dietary Macronutrient Intake with Adiposity During Childhood According to Sex: Findings from the Generation XXI Birth Cohort.

Surgery

• Demographic Factors as Determinant of Selection of Sleeve Gastrectomy or Gastric Bypass for Surgical Weight Loss.
• Review: Effects and Acceptability of Technology-Based Physical Activity Interventions in Bariatric Surgery.
• Comparison of Ambulatory Health Care Costs and Use Associated with Roux-En-Y Gastric Bypass vs Sleeve Gastrectomy.
• Review: Cardiac Surgery in Individuals with Extreme Obesity.

Drugs

• Individual Differences in the Effects of the ACTION-PAC Intervention: An Application of Personalized Medicine in the Prevention and Treatment of Obesity.
• "Lilly's tirzepatide delivered up to 22.5% weight loss in adults with obesity or overweight in SURMOUNT-1."
• GLP-1 Physiology Informs the Pharmacotherapy of Obesity.
• The Incretin/Glucagon System as a Target for Pharmacotherapy of Obesity.

Food & Diet

• Preprint: "our results suggest that [nicotinamide riboside] acts as a potent modifier of NAD+ metabolism, muscle mitochondrial biogenesis and stem cell function, gut microbiota, and DNA methylation in humans irrespective of BMI."
• RCT: Micronutrient Status of Individuals with Overweight and Obesity Following 3 Months’ Supplementation with PolyGlycopleX (PGX®) or Psyllium.
• Association of Animal and Plant Protein Intakes with Biomarkers of Insulin and Insulin-Like Growth Factor Axis.
• Associations between the Dietary Inflammatory Index with Obesity and Body Fat in Male Adolescents.

Caloric and Dietary Restriction

• RCT: Early Time-Restricted Eating Compared with Daily Caloric Restriction in Adults with Obesity.
• Integrative Epigenomic and Transcriptomic Analyses Reveal Metabolic Switching by Intermittent Fasting in Brain.

Exercise & Physical Activity

• Dissertation: Relative Importance of Physical Activity and Body Composition on Insulin Resistance in Older Adult Population.
• RCT: Impact of Obesity on the Molecular Response to a Single Bout of Exercise in a Preliminary Human Cohort.
• Systematic Review: eHealth Interventions to Promote Physical Activity in Adults with Obesity or Overweight.
• Association between Objectively Measured Physical Activity of Parents and Children: The 2015 Pelotas Birth Cohort.
• Thesis: Socioeconomic Status and Physical Activity Levels in African Americans with and without Obesity.

Economics & Sociology

• Dietary Trajectories Through the Life Course: Opportunities and Challenges.
• Beverage Availability and Price: Variations by Neighborhood Poverty Level in New York City.

Epidemiology

• Trends in Growth and Nutritional Status of High School Graduates in Hangzhou, China, 2011–2020.
• Twenty-Year Trends in Heart Failure Among U.S. Adults, 1999–2018: The Growing Impact of Obesity and Diabetes.
• Meta-Analysis: Obesity as a Predictor of Outcome Following Traumatic Brain Injury.

Psychology & Neuroscience

• The Neural Basis of Weight Control and Obesity.
• Systematic Review: Effects of Physical Activity on Social, Behavioral, and Cognitive Skills in Children and Young Adults with Autism Spectrum Disorder.

Equity and Disparities

• Research Opportunities to Address Nutrition Insecurity and Disparities.
• Racial and Ethnic Equity in Care for Hypertension and Diabetes in an Urban Indian Health Organization.
• Racial and Ethnic Disparities in COVID-19: Rate Ratios Provide an Incomplete Picture of US Trends, April 2020–March 2021.

Stigma

• Presenting Complaint: Use of Language That Disempowers Patients.
• A Comprehensive Examination of the Nature, Frequency, and Context of Parental Weight Communication: Perspectives of Parents and Adolescents.

Policy Related

• Development and Implementation of Physical Education State-Level Accountability for Student Learning and Performance.
• Population Impact of Sugar-Sweetened Beverages on Dental Caries and Overweight/Obesity in Australian Children.
• Intergovernmental Policy Opportunities for Childhood Obesity Prevention in Australia: Perspectives from Senior Officials.
• Addressing Social and Racial Justice in Public Policy for Healthy Living.

Intergenerational Effects

• Associations between Maternal Obesity and Offspring Gut Microbiome in the First Year of Life.
• Relationships between Maternal BMI and Child Cognitive Outcomes at 3 Years of Age are Buffered by Specific Early Environments in a Prospective Canadian Birth Cohort.
• Systematic Review: Dietary Patterns During Pregnancy and Gestational Weight Gain.
• Maternal Metabolic Health, Lifestyle, and Environment – Understanding How Epigenetics Drives Future Offspring Health.

Ecology, Evolution, & Energetics

• Begging Behavior Influenced Food Allocation on Creamy-Bellied Thrush (Turdus amaurochalinus) Nestlings.
• Measuring Metabolic Rate in Single Flies During Sleep and Waking States Via Indirect Calorimetry.
• Sex-Specific Body Mass Ageing Trajectories in Adult Asian Elephants.
• Reduced Mitochondrial Respiration in Hybrid Asexual Lizards.

Methods

• A New Mathematical Mixed Effect Model Was Used for Analysing the Influencing Factors of Hypoglycaemia of Newborns from Women with Gestational Diabetes Mellitus.
• Editorial: Plant Foods and Dietary Supplements: Building Solid Foundations for Clinical Trials.

Mathematical and Quantitative

• Excess Mortality Associated with Elevated Body Weight in the USA by State and Demographic Subgroup: A Modelling Study.

Commentary

• Is Cold Exposure Beneficial for Metabolic Health?
• How Is Bone Mineral Density Affected by Gender & Obesity?
• Metformin: Rejoicing in the Lost Lilac. (pdf)
• Controlling the Obesity Pandemic: Geoffrey Rose Revisited.
• Nutritional Considerations for Transgender Patients.
• Type 2 Diabetes Mellitus in Latinx Populations in the United States: A Culturally Relevant Literature Review.
• Tirzepatide Phase Three Obesity Results: Wow!
• Defining Goals for Regulating Food Marketing.

General

• Flexible Use of Memory by Food-Caching Birds.
• Many Labs 4: Failure to Replicate Mortality Salience Effect with and Without Original Author Involvement.
• Fascinating Adaptations in Amphibians.
• Reproducibility in the Social Sciences.
• Inductivism.
• Review Of: How the Other Half Eats: The Untold Story of Food and Inequality in America.
• Age and Physical Activity Levels in Companion Dogs: Results from the Dog Aging Project.

Video & Audio

• Podcast with Alan Alda: Saul Perlmutter: The Man Who Upended the Universe.
• Video: Recorded Public Session from the National Academy of Sciences Strategic Council for Research Excellence, Integrity, and Trust: Meeting 3.

Announcements

• New Jewish Culture Center, in Partnership with IU Hillel, Open on Bloomington Campus.
• Students Use Little 500 to Raise Awareness About Food Insecurity.
• White House Conference on Hunger, Nutrition, and Health.
• Applications Open: 2022 Mathematical Sciences in Obesity Research Short Course. Priority Application by May 17.
• Applications Open: 2022 Strengthening Causal Inference in Behavioral Obesity Research Short Course. Priority Application by June 17.