Obesity and Energetics Offerings

Featured

• A Neuromarker for Drug and Food Craving Distinguishes Drug Users from Non-Users.
• Low subjective social status is associated with daily selection of fewer healthy foods and more high-fat/high sugar foods.
• Randomization, Design and Analysis for Interdependency in Aging Research: No Person or Mouse Is an Island.
• Endosomal Lipid Signaling Reshapes the Endoplasmic Reticulum to Control Mitochondrial Function.

Headline vs Study

• Headline: What Causes Childhood Obesity? New Study Says a Single Gene Could Be Responsible.
• Study: Aberrant Expression of Agouti Signaling Protein (ASIP) as a Cause of Monogenic Severe Childhood Obesity... In 5 of 1,746 Children with Overweight or Obesity.

Contrary or Null Findings

• Urbanization Does Not Endanger Food Security: Evidence from China's Loess Plateau.
• RCT: Early Nutritional Intervention Does Not Prevent Long-Term Adverse Events in Women with Breast Cancer.
• Recapitulation of Anti-Aging Phenotypes by Global, but Not by Muscle-Specific, Deletion of PAPP-A in Mice.
• "We found inconsistent evidence that a child’s BMI affected their depressive and ADHD symptoms, and little evidence that a child’s BMI affected their anxiety symptoms."
• Iron Supplementation Does Not Aggravate Impaired Glucose Tolerance and Sugar Overload-Induced Genotoxicity in Rats.
• Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake.
• RCT: Eight-Hour Time-Restricted Eating Does Not Lower Daily Myofibrillar Protein Synthesis Rates.
• RCT: Acute Pre-Exercise Hydrogen Rich Water Intake Does Not Improve Running Performance at Maximal Aerobic Speed in Trained Track and Field Runners.
• RCTs: Imagined Eating & Satiety - "Priming appeared to be specific to the taste of the exposed stimulus, and satiation, contrary to prior literature, appeared to be more general. Neither colour nor flavour variety reliably moderated any of the responses."

Basic

• Review: Novel Importance of MiR-143 in Obesity Regulation.
• Angiotensin(1–7) Attenuates Visceral Adipose Tissue Expansion and Lipogenesis by Suppression of Endoplasmic Reticulum Stress Via Mas Receptor.
• Brevibacillus laterosporus BL1, a Promising Probiotic, Prevents Obesity and Modulates Gut Microbiota in Mice Fed a High-Fat Diet.
• Empagliflozin Protects Mice Against Diet-Induced Obesity, Insulin Resistance, and Hepatic Steatosis.
• L-Arginine Supplementation Regulates Energy-Substrate Metabolism in Skeletal Muscle and Adipose Tissue of Diet-Induced Obese Rats.

Scientific Rigor & Scholarly Dialogue

• Big Claims, Vexing Flaws of an Intermittent Fasting Study.
• Article: Coffee and Green Tea Consumption and Cardiovascular Disease Mortality Among People with and Without Hypertension.
• Comments: Expert Reaction to Study Looking at Coffee and Green Tea Consumption and Heart Deaths in People with Severe High Blood Pressure.

Clinical

• RCT: Comparison of an Online Versus Conventional Multidisciplinary Collaborative Weight Loss Programme in Type 2 Diabetes Mellitus.
• Review: Intermuscular Adipose Tissue in Metabolic Disease.
• Detailed Versus Simplified Dietary Self-Monitoring in a Digital Weight Loss Intervention Among Racial and Ethnic Minority Adults.
• RCT: Effects of a Web-Based Weight Loss Program on the Healthy Eating Index-NVS in Adults with Overweight or Obesity and the Association with Dietary, Anthropometric and Cardiometabolic Variables.
• RCT: Body Fat Reduction Effect of Bifidobacterium Breve B-3.

Children and Adolescents

• Trends in U.S. Adolescent Physical Activity and Obesity: A 20-Year Age-Period-Cohort Analysis.
• Meta-Analysis: Effects of Nutritional Intervention Strategies in the Primary Prevention of Overweight and Obesity in School Settings.
• Obesity, Overweight and Hyperglycemia Among Primary School Children in a Low-Middle Income Country with a Multiethnic Population.
• Fat Content in Infant Mesenchymal Stem Cells Prospectively Associates with Childhood Adiposity and Fasting Glucose.

Surgery

• Gut Adaptation After Gastric Bypass in Humans Reveals Metabolically Significant Shift in Fuel Metabolism.
• Systematic Review: The Efficacy of GLP-1RAs for the Management of Postprandial Hypoglycemia Following Bariatric Surgery.
• Protein Supplementation with Short Peptides Prevents Early Muscle Mass Loss After Roux-En-Y-Gastric Bypass.

Drugs

• Meta-Analysis: Reducing Craving and Consumption in Individuals with Drug Addiction, Obesity or Overeating Through Neuromodulation Intervention.
• Review: Drug Dosing in Hospitalized Patients with Obesity and COVID-19.
• Effectiveness and Persistence of Anti-Obesity Medications (Liraglutide 3 Mg, Lorcaserin, and Orlistat) in a Real-World Primary Care Setting.
• Effects of Jowiseungki-Tang on High Fat Diet-Induced Obesity in Mice and Functional Analysis on Network Pharmacology and Metabolomics Analysis.

Food & Diet

• Meta-Analysis: Combined Effects of Aspartame and Acesulfame-K Blends on Appetite.
• Perspective: Multi-Sectoral Strategies Needed to Establish Healthy Portion Size Norms That Disincentivize Hyperpalatable, Energy-Dense Foods and Sugary Beverages in Food Environments Linked to Obesity and Diet-Related Chronic Diseases in the United States.
• Multi-Omics Gut Microbiome Signatures in Women with Obesity: Role of Diet and Uncontrolled Eating Behavior.
• Effect of D-β-Hydroxybutyrate-(R)-1,3 Butanediol on Appetite Regulation in People with Prediabetes.

Caloric and Dietary Restriction

• RCT: Effect of an Intermittent Calorie-Restricted Diet on Type 2 Diabetes Remission.
• Effects of Dietary Methionine Restriction on Age-Related Changes in Perivascular and Beiging Adipose Tissues in the Mouse.
• Review: Energy Intake at the Intersection of the Clock and Ageing.

Exercise & Physical Activity

• Association of Longitudinal Activity Measures and Diabetes Risk: An Analysis from the National Institutes of Health All of Us Research Program.
• Review: Myokine, a Key Cytokine for Physical Exercise to Alleviate Sarcopenic Obesity.

Economics & Sociology

• Preprint: Associations of Socioeconomic Status and Obesity with Hypertension in Tibetan Adults in a Chinese Plateau Area.
• G7 Food Security Working Group: Financial Report on Food Security and Nutrition 2020. (pdf)
• Associations of Neighborhood Opportunity and Social Vulnerability with Trajectories of Childhood BMI and Obesity Among US Children.

Epidemiology

• Weight Change Across Adulthood and Accelerated Biological Aging in Middle-Aged and Older Adults.
• Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program.

Psychology & Neuroscience

• Imaginal Retraining Reduces Craving for High-Calorie Food.
• The Concept of “Metabolic Jet Lag” in the Pathophysiology of Bipolar Disorder: Implications for Research and Clinical Care.

Equity and Disparities

• Socioeconomic Disparities in Diabetes Prevalence and Management Among the Adult Population in Bangladesh.
• Neighborhood Disadvantage Is Associated with Decreased Ovarian Reserve in Women with Overweight and Obesity.
• Trends in School-Neighbourhood Inequalities and Youth Obesity: Repeated Cross-Sectional Analyses of the Public Schools in the State of California.

Stigma

• Weight Stigma Among Adolescents in Three Low- and Middle-Income Countries.
• Intuitive Eating Buffers the Link between Internalized Weight Stigma and BMI in Stressed Adults.

Policy Related

• A Scientific Transition to Support the 21st Century Dietary Transition.
• Person-First Treatment Strategies: Weight Bias and Impact on Mental Health of People Living with Obesity.
• Series of Rapid Reviews: Breakfast Consumption by School-Aged Children and Adolescents and School Performance, Weight-Related Outcomes, and Health & U.S. School Breakfast Program Best Practices, Including Models of Student Costs and Breakfast Delivery.
• A Novel Approach to Characterize State-Level Food Environment and Predict Obesity Rate Using Social Media Data: Correlational Study.

Intergenerational Effects

• Egg Introduction During Infancy Is Associated with Lower Fat Mass Index in Females at Early Adolescence.
• RCT: Maternal Well-Being and Stage of Behaviour Change During Pregnancy.
• Maternal BMI in the Preconception Period, and Association with Child zBMI Growth Rates.
• Epigenetic Age Acceleration in Mothers and Offspring 4–10 Years After a Pregnancy Complicated by Gestational Diabetes and Obesity.

Ecology, Evolution, & Energetics

• Review: Finding Balance: Understanding the Energetics of Time-Restricted Feeding in Mice.
• Chronic Intermittent Hypoxia During Sleep Causes Browning of Interscapular Adipose Tissue Accompanied by Local Insulin Resistance in Mice.
• Preprint: Age but Not Menopausal Status Is Linked to Lower Resting Energy Expenditure.

Methods

• A Conductive Hydrogel Microneedle-Based Assay Integrating PEDOT:PSS and Ag-Pt Nanoparticles for Real-Time, Enzyme-Less, and Electrochemical Sensing of Glucose.
• Machine Learning in Nutrition Research.
• Letter: The A, B, C, D's of Dietary Trials.
• Reply to H Staudacher et al.

Commentary

• The Marketing of Plant-Based Protein - the Beyond Meat Case: Making Food Alternatives Appealing to Multiple Groups of Consumers.
• Sugar May Become Healthier Through Wyss, Kraft Heinz Collaboration.
• Starvation Triggers Metabolic Rewiring Crucial for Cellular Survival.
• Tiny Patch Could Give Diabetics Painless Glucose Monitoring.
• A Metabolic Gift for Gaining Weight and Hibernating.
• Common Food Dye Can Trigger Inflammatory Bowel Diseases, Say Researchers.
• Blood-Based Metabolic Signature Outperforms Standard Method for Predicting Diet, Disease Risk: The Study Found That Machine Learning Techniques Improved Diet Prediction by 10-20%.
• Obesity Researchers Discover New Gene Mutation in Children.

General

• Collecting: A Demonic Passion. (pdf)
• WEBINAR | Considerations in the Study of Sex as a Biological Variable in Aging Research February 2, 2023 from 4-5pm ET.
• The Equality Paradox: Gender Equality Intensifies Male Advantages in Adolescent Subjective Well-Being.
• Towards a New Paradigm for ‘Journal Quality’ Criteria: A Scoping Review.
• Neurons Responsible for Maintaining Body Temperature: Study.
• The Musicality of Birds: From Charles Darwin to Hermeto Pascoal.
• Twin Research for Everyone. (pdf)
• Improving the Rigor of Mechanistic Behavioral Science: The Introduction of the Checklist for Investigating Mechanisms in Behavior-Change Research (CLIMBR).
• NIH Plans Grant-Review Overhaul to Reduce Bias.
• Glassfrogs Conceal Blood in Their Liver to Maintain Transparency.

Announcements

• IU Bloomington School of Public Health Seeks Chair of the Department of Environmental and Occupational Health.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Indiana University School of Public Health-Bloomington Is Recruiting for Tenure-Track Faculty in Every Department!

Featured

• Increased Meal Size but Reduced Meal-Stimulated Plasma Cholecystokinin Concentrations in Women with Obesity.
• RCT: Early Time-Restricted Eating Affects Weight, Metabolic Health, Mood, and Sleep in Adherent Completers: A Secondary Analysis.
• RCT: A Culturally Sensitive and Theory-Based Intervention on Prevention and Management of Diabetes.

Headline vs Study

• Headline: Healthy New Brain Food for Stressed University Students.
• RCT: No Significant Walnut-Versus-Control Effects Reported for the Primary 16-Week Outcomes of Profile of Mood States (POMS), Salivary Cortisol, or Brain-Derived Neurotrophic Factor.
• Trial Registration: The Effects of Walnuts on General Well­being and Mood Related Factors in a Sample of University Students.

Contrary or Null Findings

• "...fecal microbiota transplantation did not reduce the body weight of patients undergoing bariatric surgery."
• RCT: Time-Restricted Eating Did Not Alter Insulin Sensitivity or β-Cell Function in Adults with Obesity.
• RCT: "Persons with T2DM on a 6-month, calorie-unrestricted, LCHF diet had greater clinically meaningful improvements in glycemic control and weight compared with those on an HCLF diet, but the changes were not sustained 3 months after intervention."
• RCT: "Adults with overweight and obesity experience modest weight loss in response to an exercise program, but there does not appear to be an optimal time to exercise."
• "The overall risk of fractures increases years after BS" [bariatric surgery].
• Co-Diet Supplementation of Low Density Polyethylene and Honeybee Wax Did Not Influence the Core Gut Bacteria and Associated Enzymes of Galleria mellonella Larvae (Lepidoptera: Pyralidae).
• Supplementation of Graded Levels of Rumen-Protected Choline to a Pelleted Total Mixed Ration Did Not Improve the Growth and Slaughter Performance of Fattening Lambs.
• RCT: Plasma FGF21 Levels are Not Associated with Weight Loss or Improvements in Metabolic Health Markers upon 12 Weeks of Energy Restriction.
• Contrary Associations of Positive End-Expiratory Pressure on Intracranial Pressure in Severe Brain Injury Patients with Versus without Obesity.

Basic

• Fat Quality Impacts the Effect of a High-Fat Diet on the Fatty Acid Profile, Life History Traits and Gene Expression in Drosophila melanogaster.
• Revised Protein Sparing Diet in Obesity and Type 2 Diabetes Mellitus.

Scientific Rigor & Scholarly Dialogue

• Letter: Measurement Rigor Is Not a Substitute for Design Rigor in Causal Inference: Increased Physical Activity Does Cause (Modest) Weight Loss.
• Response: Exercise Is Essential for Health but a Poor Tool for Weight Loss: A Reply to Allison and Colleagues.
• Editorial: Does Physical Activity Cause Weight Loss?
• Use of Behavioural Change Taxonomies in Systematic Reviews and Meta-Analyses Regarding Obesity Management.

Clinical

• Navigating Data Governance Approvals to Use Routine Health and Social Care Data to Evidence the Hidden Population with Severe Obesity: A Case Study from a Clinical Academic’s Perspective.
• PodCast: The State of Obesity Care: Better Policies for Older Adults.
•  Meta-Analysis: Distribution of Energy Intake Across the Day and Weight Loss.
• RCT: Mindful Eating for Weight Loss in Women with Obesity.

Children and Adolescents

• Systematic Review: The Effect of Maternal Overweight and Obesity Pre-Pregnancy and During Childhood in the Development of Obesity in Children and Adolescents.
• The Role of Molecular and Hormonal Factors in Obesity and the Effects of Physical Activity in Children.
•  Meta-Analysis: The Prevalence of Obesity Among Children with Type 2 Diabetes.
• Book Chapter: Obesity in Children: Recent Insights and Therapeutic Options.
• Treating Obesity in Children and Adolescents with Special Healthcare Needs.
• Risk Factors, Clinical Consequences, Prevention, and Treatment of Childhood Obesity.
• Analysis of Urinary Endothelin-I Levels in Late Adolescents with Obesity.
• Promoter Methylation Status of RORC, IL17A, and TNFA in Peripheral Blood Leukocytes in Adolescents with Obesity-Related Asthma.

Surgery

• Corset Trunkoplasty Is Able to Preserve Postoperative Abdominal Skin Sensation in Massive Weight Loss Patients.
• Adverse Right Ventricular Remodelling, Function, and Stress Responses in Obesity: Insights from Cardiovascular Magnetic Resonance.

Drugs

• A Study on Cancer-Obesity-Treatment Model with Quadratic Optimal Control Approach for Better Outcomes.
• Exposure to Metal Mixtures and Overweight or Obesity Among Chinese Adults.
• Review: Kidney Damage Caused by Obesity and Its Feasible Treatment Drugs.
• The Rheumatoid Arthritis Drug Auranofin Lowers Leptin Levels and Exerts Antidiabetic Effects in Obese Mice.

Food & Diet

• Fat and Not Sugar as the Determining Factor for Gut Microbiota Changes, Obesity and Related Metabolic Disorders in Mice.
• Intake of Slow-Digesting Carbohydrates Is Related to Changes in the Microbiome and Its Functional Pathways in Growing Rats with Obesity Induced by Diet.
• Understanding the Complex Interactions between Coffee, Tea Intake and Neurologically Relevant Tissues Proteins in the Development of Anxiety and Depression.
• Proceedings of a Workshop: Alternative Protein Sources: Balancing Food Innovation, Sustainability, Nutrition, and Health.
• Scoping Review: Measurement Tools to Assess Usual Dietary Intake and Physical Activity in Individuals with Autism Spectrum Disorder.

Caloric and Dietary Restriction

• Low-Cost Thermoregulation of Wild Sloths Revealed by Heart Rate and Temperature Loggers.
• Thermal and Rheological Study of Artificial and Natural Powder Tabletop Sweeteners.
• Molecular Mechanisms and Pathophysiological Pathways of High-Fat Diets and Caloric Restriction Dietary Patterns on Pain.

Exercise & Physical Activity

• Association between Childcare Movement Behaviour Compositions with Health and Development Among Preschoolers.
• Population Characteristics Associated with Adherence to Prenatal Group-Based Exercise Programs.
• RCT: A Christmas Themed Physical Activity Intervention to Increase Participation in Physical Activity During Advent.
• Psychometric Properties of the Arabic Version of Physical Activity Questionnaire for Adolescents (PAQ-A).
• Systematic Review: Correlates of Physical Activity and Sedentary Behaviour in Children Attending Before and After School Care.

Economics & Sociology

• Overlooked and Under-Evidenced: Community Health and Long-Term Care Service Needs, Utilization, and Costs Incurred by People with Severe Obesity.
• Do Top-Grossing American Movies Portray Healthy and Unhealthy Foods Differently? A Systematic Analysis of Food in Film.

Epidemiology

• The Association between Breakfast Macronutrient Composition and Body Weight, in Preadolescence: An Epidemiological Study Among Schoolchildren.
• Relationship between Anthropometric Indices and Arterial Stiffness: Insights from an Epidemiologic Study.

Psychology & Neuroscience

• BMI and Childhood Symptoms of Depression, Anxiety, and Attention-Deficit Hyperactivity Disorder: A Within-Family Mendelian Randomization Study.
• Recent Updates on Associations Among Various Obesity Metrics and Cognitive Impairment: From BMI to Sarcopenic Obesity.
• Mediterranean Diet, Physical Activity, and Family Characteristics Associated with Cognitive Performance in Italian Primary School Children.
• Association between Physical Health and Physical Activity Behaviors for Children Aged 3–6 Years in Kindergarten: A Cross-Sectional Study from China.
• Mendelian Randomization Study: Causal Association between Obesity, Circulating Glutamine Levels, and Depression.
• Preprint: Gut Microbiome Proles are Related to Atypical Antipsychotic Associated Overweight in Asian Children with Psychiatric Disorder.
• The Prevalence of Obesity and Lifestyle Behaviors of Parents of Youth with Intellectual and Developmental Disabilities.

Equity and Disparities

• Effects of Socioeconomic Status on Nutrition and Nutrition Policy Studies in Asia.
• Health Inequities in the USA: A Role for Dietary Acid Load? Results from the National Health and Nutrition Examination Surveys.
• Secondary Analysis of RCT: Influence of Nutritional Status on a Family-Centered Care Intervention for Older Adults with Cognitive Impairment Following Hip-Fracture Surgery.

Stigma

• Indigenous Research on Social Bias of Evaluating People with Obesity.
• What Is It Like to Live with Obesity in Peninsular Malaysia? A Qualitative Study.

Policy Related

• A Global Analysis of National Dietary Guidelines on Plant-Based Diets and Substitutions for Animal-Based Foods.
• Health Improvements of Older Adults Based on Benefit Duration: Lessons from Korean Social Pension Policies.
• Healthfulness of Fast-Food and Full-Service Restaurants in 16 Georgia Counties After Mandatory Menu Labeling.
• Qualitative Study: Health Promotion Partnership to Promote Physical Activity in Swedish Children with ASD and ADHD.

Intergenerational Effects

• Appetitive Motivation and Associated Neurobiology Change Differentially Across the Life Course of Mouse Offspring Exposed to Peri- and Postnatal High Fat Feeding.
• Self-Regulation Linking the Quality of Early Parent–child Relationship to Adolescents' Obesity Risk and Food Consumption.
• Early Childhood Exposure to Maternal Smoking and Obesity: A Nationwide Longitudinal Survey in Japan.
• Individual and Parental Factors of Adolescents’ MHealth App Use: Nationally Representative Cross-Sectional Study.

Ecology, Evolution, & Energetics

• Preprint: Population Divergence in Maternal Investment and Embryo Energy Use and Allocation Reveals Adaptive Responses to Cool Climates.
• Pronounced Differences in Heart Rate and Metabolism Distinguish Daily Torpor and Short-Term Hibernation in Two Bat Species.

Methods

• cRCT: Active vs Traditional Methods of Recruiting Children for a Clinical Trial in Rural Primary Care Clinics.
• Review: Food Composition Databases in the Era of Big Data: Vegetable Oils as a Case Study.
• BMI Decline Patterns and Relation to Dementia Risk Across Four Decades of Follow-Up in the Framingham Study.

Commentary

• The Challenge of Defining the Optimal Lifestyle Weight Loss Intervention for Real-World Settings.
• "In IJO, don't miss the debate between Herman Pontzer and David Allison et al regarding the value of #exercise for #WeightLoss."
• Surprise! Vague Weight Loss Advice Fails Us.
• NASEM Report: Alternative Protein Sources Balancing Food Innovation, Sustainability, Nutrition, and Health: Proceedings of a Workshop–in Brief (2022).
• Front-of-Package Nutrition Labeling as a Driver for Healthier Food Choices: Lessons Learned and Future Perspectives.
• MicroRNAs: A Crossroad That Connects Obesity to Immunity and Aging.
• Is There an Obesity Paradox in Transcatheter Aortic Valve Replacement?
• Therapeutic Potential of Gallic Acid in Obesity: Considerable Shift!

General

• Different, but the Same: Inferring the Hunting Behaviour of the Hypercarnivorous Bush Dog (Speothos venaticus) Through Finite Element Analysis.
• The Association of Peripheral and Central Olfaction with Frailty in Older Adults.
• Podcast Episode 227: Aquaponics: The Future of Sustainable Food – Dr. Steven Summerfelt & Molly Stanek.
• Ambient Temperature and Ambulatory Blood Pressure: An Hourly–level, Longitudinal Panel Study.
• Preprint: Is Chimerism Associated with Cancer Across the Tree of Life?
• RCT: Does Coffee Affect Bowel Recovery After Minimally Invasive Colectomy?
• Survey of Belgian Owners’ Perspectives on Quality of Life and Difficulties During a Weight-Loss Programme in Obese Cats.
• Peeking and Lying in the Temptation Resistance Paradigm in 2.5-Year-Olds: The Role of Inhibitory Control.
• Person-First Treatment Strategies: Weight Bias and Impact on Mental Health of People Living with Obesity.

Announcements

• IU Bloomington School of Public Health Seeks Chair of the Department of Environmental and Occupational Health.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Indiana University School of Public Health-Bloomington Is Recruiting for Tenure-Track Faculty in Every Department!
• Gleaners of Indiana announces new ten-week program to address food inequity.

Featured

• Estimating Running Speed from Wrist- or Waist-Worn Wearable Accelerometer Data: A Machine Learning Approach.
• RCT: "These data suggest a potential anti-inflammatory role of semaglutide in obesity."
• Transgenerational Transmission of Aspartame-Induced Anxiety and Changes in Glutamate-GABA Signaling and Gene Expression in the Amygdala.

Headline vs Study

• Headline: Anti-Inflammatory Diet Improves Female Fertility, Study Finds.
• Study: Self-Reported Dietary Patterns and Fecundability in 2 Prospective Cohorts. Associations (Not Necessarily Causal Improvement) Seen with Alternative Mediterranean Diet, Healthy Eating Index-2010, the Danish Dietary Guidelines, or the Dietary Inflammatory Index in One or Both Cohorts.

Contrary or Null Findings

• RCT: No Significant Effect of Liraglutide on Weight or BMI Loss in Children and Adolescents with Prader–Willi Syndrome and Obesity.
• RCT: "...there were no significant treatment effects (Group x Time) for any of the PA outcomes - total PA, LPA, MPA, sedentary behavior, or steps [in trial of] Effects of a behavioral intervention on physical activity, diet, and health-related quality of life in pregnant women with elevated weight."
• RCT: No significant effects on most anthropometric variable "Effects of synbiotic supplementation on anthropometric indices and body composition in overweight or obese children and adolescents."
• RCT: "Contrary with our hypothesis, our results showed no difference in the change in BMI status between treatment arms...[in] An addiction-based digital weight loss intervention."
• "contrary to what has been observed in previous studies in Spain and elsewhere, our study shows that living without a partner has no effect on low birth weight."
• "Contrary to our predictions, herbivore traits did not influence differences in the bottom-up or top-down effects except for stronger top-down effects for shelter-builders."
• "Contrary to expectation, everyday discrimination experiences were more strongly associated with body image disturbance and eating disorder/ body dysmorphic disorder pathology in heterosexual men than in gay men (all p ≤ .05)."
• Review: "Most existing models of childhood obesity prevention have not worked, yielding little to no effect on improving weight status or the proximal health behaviors most attributed to obesity risk: nutritional intake, physical activity, sedentary behaviors, and sleep."

Basic

• Role of PVAT in Obesity-Related Cardiovascular Disease Through the Buffering Activity of ATF3.
• Blockade of CXXC5-Dishevelled Interaction Inhibits Adipogenic Differentiation, Obesity, and Insulin Resistance in Mice.
• Time-Dependent Metabolome and Fatty Acid Profile Changes Following a High-Fat Diet Exposure in Drosophila melanogaster.
• Interleukin-33 Inhibits Glucose Uptake in Human Adipocytes and Its Expression in Adipose Tissue Is Elevated in Insulin Resistance and Type 2 Diabetes.
• Thesis: Astrocytes Regulate Brain Fatty Acid Sensitivity and Food Intake Via Cluster of Differentiation (CD)36 in Diet-Induced Obesity.
• Endothelin Receptor Antagonism Improves Glucose Tolerance and Adipose Tissue Inflammation in an Experimental Model of Systemic Lupus Erythematosus.

Scientific Rigor & Scholarly Dialogue

• The Wisdom of Collaborating with Adversaries.
• A Meta-Epidemiological Study of Positive Results in Clinical Nutrition Research: The Good, the Bad and the Ugly of Statistically Significant Findings.

Clinical

• RCT: Effects of Synbiotic Supplementation on Anthropometric Indices and Body Composition in Children and Adolescents with Overweight or Obesity.
• RCT: An Addiction-Based Digital Weight Loss Intervention.
• FDA: Body Sculpting: Information and Resources About Benefits and Risks of Non-Invasive Body Contouring Devices.
• "Weight-loss advice from GPs to patients with obesity rarely included effective methods": What Advice Do General Practitioners Give to People Living with Obesity to Lose Weight? A Qualitative Content Analysis of Recorded Interactions.

Children and Adolescents

• The Influence of Increased Dairy Product Consumption, as Part of a Lifestyle Modification Intervention, on Diet Quality and Eating Patterns in Female Adolescents with Overweight/Obesity.
• Prolonged Body Weight Gain, Lifestyle Changes and Health-Related Quality of Life in Children During the COVID-19 Pandemic Lockdown: A Follow-Up Study.
• Bioactive Compounds in Childhood Obesity and Associated Metabolic Complications: Current Evidence, Controversies and Perspectives.
• Changes in DNA Methylation of Clock Genes in Adolescents with Obesity After a Short-Term Body Weight Reduction Program: A Possible Metabolic and Endocrine Chrono-Resynchronization.

Surgery

• Higher Magnesium Levels are Associated with Better Glycaemic Control and Diabetes Remission Post-Bariatric Surgery.
• Comparison of a Pre-Bariatric Surgery Very Low-Calorie Ketogenic Diet and the Mediterranean Diet Effects on Weight Loss, Metabolic Parameters, and Liver Size Reduction.
• The Importance of Endogenously Secreted GLP-1 and GIP for Postprandial Glucose Tolerance and β-Cell Function After Roux-En-Y Gastric Bypass and Sleeve Gastrectomy Surgery.
• The Role of the Gut Microbiome in Pediatric Obesity and Bariatric Surgery.

Drugs

• Hypothalamic Anorexigenic Signaling Pathways (Leptin, Amylin, and Proopiomelanocortin) are Semaglutide (GLP-1 Analog) Targets in Obesity Control in Mice.
• Tirzepatide: First Approval.
• Pharmacologic Therapy for Obesity.

Food & Diet

• Post-Exercise Skimmed Milk, but Not a Sucrose Beverage, Decreases Energy Intake at the Next Meal Compared to a Placebo Beverage in Active Males.
• Rhamnose Displays an Anti-Obesity Effect Through Stimulating Adipose Dopamine Receptors and Thermogenesis.

Caloric and Dietary Restriction

• Metabolomics of Testosterone Enanthate Administration During Severe-Energy Deficit.
• Deep Phenotyping and Lifetime Trajectories Reveal Limited Effects of Longevity Regulators on the Aging Process in C57BL/6J Mice.
• Early Life Low-Calorie Sweetener Consumption Impacts Energy Balance During Adulthood.

Exercise & Physical Activity

• Longitudinal Association of Childhood Physical Activity and Physical Fitness with Physical Activity in Adolescence.
• Association between Nap Habituality and Sedentary Time and Physical Activity in Early Childhood.

Economics & Sociology

• Consumerism and Gendering in Food Culture: A Study of Urban Kerala.
• Socio-Economic Difference in Purchases of Ultra-Processed Foods in Australia: An Analysis of a Nationally Representative Household Grocery Purchasing Panel.
• Designing Financial Incentives for Health Behaviour Change: A Mixed-Methods Case Study of Weight Loss in Men with Obesity.

Epidemiology

• Multi-Level Analysis Reveals the Association between Diabetes, Body Mass Index, and HbA1c in an Iraqi Population.
• The Association of Problematic Gaming Characteristics with Dietary Habits Among Finnish Vocational School Students.
• Historical and Cultural Aspects of Obesity: From a Symbol of Wealth and Prosperity to the Epidemic of the 21st Century.

Psychology & Neuroscience

• Apple Versus Chocolate: Evidence for Discrimination of Distension-Related and Calorie-Related Satiety Signals in Post-Prandial Fullness and Hunger, and in the Quality and Location of Other Body Sensations.
• Astrocyte Reactivation in Medial Prefrontal Cortex Contributes to Obesity-Promoted Depressive-Like Behaviors.

Equity and Disparities

• Relationship between Olfactory Function and BMI in Normal Weight Healthy Subjects and Patients with Overweight or Obesity.
• RCT: Different Isocaloric Meals and Adiposity Modify Energy Expenditure and Clinical and Metabolomic Biomarkers During Resting and Exercise States in a[n].. Acute Trial of Normal-Weight and Men with Overweight/Obesity.
• Content Analysis of Websites of Didactic Programs in Dietetics for Evidence of Diversity, Equity, and Inclusion.

Stigma

• Weight Stigma Speaks Italian, Too.
• Cancer Prevention in Females with and Without Obesity: Does Perceived and Internalised Weight Bias Determine Cancer Prevention Behaviour?
• Practice Considerations and Attitudes Regarding Patients with Large Bodies in Medical Radiation Sciences.

Policy Related

• Systematic Review: Acceptability of Policies Targeting Dietary Behaviours and Physical Activity.
• Applying a Systems Perspective to Understand the Mechanisms of the European School Fruit and Vegetable Scheme.
• Public Preferences for Policies Promoting a Healthy Diet: A Discrete Choice Experiment.
• From Harmful Nutrients to Ultra-Processed Foods: Exploring Shifts in ‘foods to Limit’ Terminology Used in National Food-Based Dietary Guidelines.
• Development of a Framework to Guide Research Into Policies Promoting Physical Activity and Healthy Diets in the European Context: The System-Based Policy Evaluation Network (PEN) Framework.
• Editorial: Pay for Performance- When Slogans Overtake Science in Health Policy.

Intergenerational Effects

• Postnatal Leptin Levels Correlate with Breast Milk Leptin Content in Infants Born Before 32 Weeks Gestation.
• Transgenerational Associations of Parental Famine Exposure in Early Life with Offspring Risk of Adult Obesity in China.
• A Maternal High-Fat Diet Causes Anxiety-Related Behaviors by Altering Neuropeptide Y1 Receptor and Hippocampal Volumes in Rat Offspring: The Potential Effect of N-Acetylcysteine.

Ecology, Evolution, & Energetics

• The Big Brown Bat (Eptesicus fuscus) Reduces Its Body Mass During Winter in a Tropical Montane Ecosystem of Central Mexico.
• Review: Indirect Calorimetry: Should It Be Part of Routine Care or Only Used in Specific Situations?

Methods

• Continuous Glucose Monitoring and Metrics for Clinical Trials: An International Consensus Statement.
• Use of a Focus Group-Based Cognitive Interview Methodology to Validate a Cooking Behavior Survey Among African-American Adults.
• Toward Systems Models for Obesity Prevention: A Big Role for Big Data.

Mathematical and Quantitative

• Sensitivity Analysis of a Predictive Model of Social Network Impact on Obesity and Its Chronic Complications.
• Control Strategies of a Stochastic Social Obesity Epidemic Model in the Region of Valencia, Spain.

Commentary

• Are We Suffering a Deficit of Forgiveness?
• The Mythical Race between Diet and Exercise.
• What are Whole Grains, Anyway?
• New Potential Molecular Mechanism in Obesity Identified.
• Imagining 'Eat' Together: The School Meal.
• Take the Stairs for a Longer Life?
• With Early Data and a Possible Advantage, Amgen Enters the Obesity Drug Race.
• The New Obesity Breakthrough Drugs.

General

• How Do Microscopic Creatures Called Tardigrades Survive Being Completely Dried Out?
• PLD3 Affects Axonal Spheroids and Network Defects in Alzheimer’s Disease.
• Finerenone in Mild to Severe Chronic Kidney Disease and Type 2 Diabetes: A Fidelity Subgroup Analysis in Patients with Heart Failure.
• Why Do Some Dogs Chase Squirrels? Study Finds Genetic Links to Canine Quirks.
• Foodborne Nanoparticles May Predispose Infants to Food Allergy.
• How People Wake Up Is Associated with Previous Night’s Sleep Together with Physical Activity and Food Intake.
• People Can Have Food Sensitivities Without Noticeable Symptoms – Long-Term Consumption of Food Allergens May Lead to Behavior and Mood Changes.
• Can Florida’s Gentle Manatees Rebound—Again?
• Association of Muscle Mass Measured by D3-Creatine (D3Cr), Sarcopenic Obesity, and Insulin-Glucose Homeostasis in Postmenopausal Women.

Announcements

• IU Research Contributes to First FDA-Approved Drug to Delay Onset of Type 1 Diabetes.
• IU Bloomington School of Public Health Seeks Chair of the Department of Environmental and Occupational Health.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Indiana University School of Public Health-Bloomington Is Recruiting for Tenure-Track Faculty in Every Department!

Featured

• Humor & Physics: Lose Weight the Slow and Incredibly Difficult Way.
• Just Noticeable Difference in Sweetness Perception of Cola: Small Changes in Sugar are Noticeable.
• Machine Learning Modeling Practices to Support Principles of Artificial Intelligence and Ethics in Nutrition Research.

Headline vs Study

• Headline: Eating Fewer Than 3 Meals Per Day Can Shorten Life Span, Study Says. Plus, Why Breakfast Really Might Be the Most Important Meal of the Day.
• Press Release: Food for Thought: If You Eat and When You Eat Can Impact Your Mortality.
• Study: Self-Reported Meal Skipping and Shorter Meal Intervals are Associated with Increased Risk of All-Cause and Cardiovascular Disease Mortality Among US Adults. Causation Not Necessarily Established.

Contrary or Null Findings

• Meta-Analysis: Rapamycin, Not Dietary Restriction, Improves Resilience Against Pathogens [in Mice].
• RCT: "Potato and Bean diets low in energy density were equally effective [or equally ineffective] in reducing insulin resistance and promoting weight loss in individuals with impaired blood glucose control."
• RCT: "Weight loss did not modify macronutrient specific response of hormones and satiety in people with overweight and obesity without metabolic disease."
• RCT: "Hypocaloric diet with lower meal frequency did not affect weight loss, body composition and insulin responsiveness..."
• Vitamin D Supplementation Is Not Preventative for Statin-Associated Muscle Symptoms or Statin Discontinuation.
• No Evidence to Support a Causal Relationship between Circulating Adiponectin Levels and Ankylosing Spondylitis.
• No Evidence That Spice Consumption Is a Cancer Prevention Mechanism in Human Populations.
• "Contrary to expectations, overweight male politicians were rated lowest on these [positive] characteristics."

Basic

• Anti-Obesity Effects of Red Pepper (Capsicum annuum L.) Leaf Extract on 3T3-L1 Preadipocytes and High Fat Diet-Fed Mice.
• Prebiotic Oligofructose Protects Against High-Fat Diet-Induced Obesity by Changing the Gut Microbiota, Intestinal Mucus Production, Glycosylation and Secretion.
• Exercise Training Upregulates Cardiac Mtp Expression in Drosophila Melanogaster with HFD to Improve Cardiac Dysfunction and Abnormal Lipid Metabolism.
• The Effects of a Green Rooibos (Aspalathus linearis) Extract on Metabolic Parameters and Adipose Tissue Biology in Rats Fed Different Obesogenic Diets.
• Effect of Intermittent Fasting and Complete Fasting on Biochemical and Histological Parameters in High Fat High Sugar Induced Rat Model of Obesity.
• Exercise Training Prevents Obesity/ Diabetes-Induced Activation of Inflammatory Signaling in Rat Brown Adipose Tissue.
• Resistance Exercise Training-Induced Skeletal Muscle Strength Provides Protective Effects on High-Fat-Diet-Induced Metabolic Stress in Mice.

Scientific Rigor & Scholarly Dialogue

• Retraction Watch: A [Sport Science] Paper Used Capital T’s Instead of Error Bars. But Wait, There’s More!
• Article: Association between Dietary Habits in Midlife with Dementia Incidence over a 20-Year Period.
• Commentary: A Response to the Recent Study ‘Association between Dietary Habits in Midlife with Dementia Incidence over a 20 Year Period’ from the Olive Wellness Institute Scientific Advisory Committee.

Clinical

• Systematic Review: The Effect of Weight Loss Interventions for Obesity on Fertility and Pregnancy Outcomes.
• RCT: Therapeutic Effects of Butyrate on Pediatric Obesity.
• RCT: Mid- and Long-Term Changes in Satiety-Related Hormones, Lipid and Glucose Metabolism, and Inflammation After a Mediterranean Diet Intervention with the Goal of Losing Weight.
• Treating Chronic Diseases Without Tackling Excess Adiposity Promotes Multimorbidity.

Children and Adolescents

• Review: Anti-Obesity Pharmacotherapy for Treatment of Pediatric Type 2 Diabetes.
• RCT: Different Protein Intake in the First Year and Its Effects on Adiposity Rebound and Obesity Throughout Childhood.
• Mothers as Advocates for Healthier Lifestyle Behaviour Environments for Their Children.
• An Internet-Based Educational Intervention for Mothers Targeting Preschoolers’ Weight Management Promotion.

Surgery

• 2022 ASMBS/IFSO Guidelines on Indications for Metabolic and Bariatric Surgery.
• "Bariatric surgery remains safe and effective therapy for chronically immunosuppressed patients with excellent long-term outcomes for patients with moderate to severe obesity."
• Effect of Weight Regain on Body Composition and Metabolic Biomarkers After Sleeve Gastrectomy.

Drugs

• Review: Anti-Obesity Effects of Phytochemicals Through Wnt/β-Catenin Signaling Pathway.
• Review: Anti-Obesity Siddha Medicinal Plants.
• Can Homeopathic Medicine Chelidonium Majus Serve a Dual Role of an Anti-Obesity and Anti-Diabetic Agent?
• Discovery of Eukaryotic Cellular Receptor for Withaferin A, a Multifaceted Drug from Withania Somnifera Plant.
• Racial and Ethnic Disparities in Financial Barriers Among Adults with Overweight and Obesity Eligible for Semaglutide in the United States.

Food & Diet

• RCT: "Green Mediterranean diet reduces twice as much visceral fat as traditional Mediterranean diet."
• "During 2017–March 2020, less than one-third of U.S. adults had heard of MyPlate and less than one-tenth had tried to follow the recommendations." (pdf)

Caloric and Dietary Restriction

• Systematic Review: Investigating the Effectiveness of Very Low-Calorie Diets and Low-Fat Vegan Diets on Weight and Glycemic Markers in Type 2 Diabetes Mellitus.
• Systematic Review: Effects of Time-Restricted Feeding and Ramadan Fasting on Body Weight, Body Composition, Glucose Responses, and Insulin Resistance.
• Dissertation: Do Sex and Age Influence the Metabolic and Cardiovascular Consequences of Caloric Restriction?

Exercise & Physical Activity

• Tracking Possible Differences between Female- and Male Staff in Promoting Physical Activity Towards Girls and Boys in the Outdoor Playground of the Kindergarten.
• Effects of Creatine Monohydrate Timing on Resistance Training Adaptations and Body Composition After 8 Weeks in Male and Female Collegiate Athletes.
• The Influence of Exercise Training Versus Intensive Insulin Therapy on Insulin Resistance Development in Type 1 Diabetes.

Economics & Sociology

• RCT: Effectiveness of Goal-Directed and Outcome-Based Financial Incentives for Weight Loss in Primary Care Patients with Obesity Living in Socioeconomically Disadvantaged Neighborhoods.
• "Increasing sleep duration was associated with a decreased risk of overweight/obesity, but the association was not present in adolescents from racial/ethnic minority groups (i.e. Hispanic) and those with low socioeconomic status."

Epidemiology

• Obesity Marker Trajectories and Cognitive Impairment in Older Adults: A 10-Year Follow-Up in Taichung Community Health Study for Elders.
• Adipose Tissue Insulin Resistance Is Not Associated with Changes in the Degree of Obesity in Children and Adolescents.

Psychology & Neuroscience

• "Our findings provide evidence in support of the neuroinflammation and neuronal stress theories of overeating, specifically, with greater area deprivation influencing health outcomes of obesity via brain structure alterations."
• The Immediate Effect of Overnutrition and Fluoxetine Treatment During the Critical Period of Development on the Hippocampus.
• Assessing Adolescents' Readiness for Action and Attitudes Toward Obesity Prevention: Instrument Development and Psychometric Properties.
• Food-Induced Brain Activity in Children with Overweight or Obesity Versus Normal Weight.

Equity and Disparities

• RCT: Reaching High-Risk Black Adults for Diabetes Prevention Programming During a Pandemic.
• The “Our Voice” Method: Participatory Action Citizen Science Research to Advance Behavioral Health and Health Equity Outcomes.
• Home Physical Activity Environments of Racially/Ethnically Diverse and Immigrant/Refugee Children.
• African American Patients Experience Worse Outcomes Than Hispanic Patients Following Bariatric Surgery.

Stigma

• How Do Looking Patterns, Anti-Fat Bias, and Causal Weight Attributions Relate to Adults' Judgements of Child Weight?
• The Impact of a Values Affirmation Intervention on Body Dissatisfaction and Negative Mood in Women Exposed to Fitspiration.
• Daily Weight Stigma Experiences, and Disordered and Intuitive Eating Behaviors Among Young Adults with Body Dissatisfaction.

Policy Related

• Systematic Review: The Impact of Mass-Media Campaigns on Physical Activity.
• Review: Estimating the Impact of Nutrition and Physical Activity Policies with Quasi-Experimental Methods and Simulation Modeling.
• Short Commentary: From Childhood Obesity Risk to Healthy Growth in the U.S.: A 10-Year Social Work Research & Policy Update.
• Leveraging a Community Engaged Citizen Science Method to Contextualize the New Orleans Food Environment.
• Using GRADE Evidence to Decision Frameworks to Support the Process of Health Policy-Making: An Example Application Regarding Taxation of Sugar-Sweetened Beverages.
• Public Preferences for Policies Promoting a Healthy Diet.
• The Impact of the ‘Planning Health in School’ Program on a Pair of Twins with Obesity.

Intergenerational Effects

• Meta-Analysis: Pre-Pregnancy Maternal BMI and Placental DNA Methylation Identifies 27 CpG Sites with Implications for Mother-Child Health.
• Maternal Diabetes in Youth-Onset T2D Is Associated with Progressive Dysglycemia and Risk of Complications.
• Is Small for Gestational Age Status Independently Correlated with Body Composition During Childhood?
• Effects of Bisphenol a (BPA) Substitutes on the Prenatal and Cardiovascular Systems.
• Intergenerational Pathways between Parental Experiences of Adverse Childhood Experiences and Child Weight: Implications for Intervention.

Ecology, Evolution, & Energetics

• TRH and NPY Interact to Regulate Dynamic Changes in Energy Balance in Male Zebra Finch.
• Intestinal Plasticity and Metabolism as Regulators of Organismal Energy Homeostasis.

Methods

• Nascent to Novel Methods to Evaluate Malnutrition and Frailty in the Surgical Patient.
• Smartwatch-Based Bioimpedance Analysis for Body Composition Estimation: Precision and Agreement with a 4-Compartment Model.
• Mean Intake and Trends of Whole-Grain Food Consumption Varies by Whole-Grain Definition.

Commentary

• Are Americans Eating Enough Whole Grains? It Depends on Who You Ask.
• The Most Damaging Exercise Myth.
• Why 2023 Will Be the Year of Strength Training for Longevity.
• Regular Physical Activity May Improve Vaccine Effectiveness Against COVID-19 Outcomes.
• The Real Benefits of Walking in a Winter Wonderland.
• Psychological Perspectives on Consumer Obesity.
• ”Why are So Many of Us Fat? Pandemic Obesity, and the Absence of Mystery”.
• A Unified Definition of Whole-Grain Foods Is Needed.

General

• "New predictive model of the touchdown times in a high level 110 m hurdles."
• Serum Syndecan-4 Correlates with Blood Pressure and Cardiovascular Parameters but Not Proinflammatory Markers in Healthy Older Women.
• Diabetes, Metformin Use, and Risk of Non-Hodgkin's Lymphoma in Postmenopausal Women.
• War in Ukraine: The Rationale “Wait-And-See” Mode of Global Food Markets.
• Cannabis Use Among Pregnant Women Under Different Legalization Frameworks in the United States.
• Pupating Ants Make Milk — and Scientists Only Just Noticed.
• Association of Dietary Sodium, Potassium, Sodium/Potassium, and Salt with Objective and Subjective Cognitive Function Among the Elderly in China.
• In Praise of Research in Fundamental Biology.

Announcements

• Healthy People 2030’s Population Data are Here!
• New Book: Outlive the Science and Art of Longevity.
• Redesigning Diabetes Technology to Detect Low Blood Sugar in Older Adults with Diabetes and Alzheimer’s Disease.
• IU Bloomington School of Public Health Seeks Chair of the Department of Environmental and Occupational Health.
• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Indiana University School of Public Health-Bloomington Is Recruiting for Tenure-Track Faculty in Every Department!