Featured
Headline vs Study
Contrary or Null Findings
- "Contrary to expectations, adherence to plant-based diet did not mitigate the negative effects of unhealthy supper choices on cognitive function."
- RCT: "No clinically significant changes were observed in body weight, BMI, hematological indices, or renal function in Safety of Lactiplantibacillus plantarum K014 in Healthy Adults."
- "Contrary to our hypothesis, we found no change in fasting blood glucose levels or in the area under the curve with the GTT, indicating that the HF diet and OVX together had no effect on glucose handling in the hypertensive BPH/2J mice."
- "[C]ontrary to our initial hypotheses, core temperature seems to reduce more rapidly in males, skin temperatures appear to be similar between the sexes, and higher metabolic rates in males cannot solely be attributed to body morphology, especially to BSA-to-mass ratio."
- "[C]ontrary to our hypothesis, plasma calcium levels were elevated after three days at high altitude (ANOVA main effect p=0.026; SL: 4.8±0.98 mg/uL; HA: 5.6±0.77 mg/uL) but did not differ across Acetazolamide and placebo treatments (p=0.32)."
- "Contrary to our predictions, succinate concentrations increased 39-fold during torpor, peaked early during arousal but declined in IBE… These results suggest that hibernation presents a hypoxic challenge with potential for oxidative stress upon reoxygenation during arousal."
- "Contrary to predictions that resting should remain invariant as an energetic baseline, resting was the most responsive activity to environmental variation, functioning as a behavioural buffer that absorbs fluctuations in resource availability and thermal conditions, although this flexibility is constrained above a critical temperature threshold with implications for population resilience under projected climate warming."
- "Contrary to our expectations, changes in fecal bacterial composition did not affect innate immunity and body composition with regard to fat and lean mass and bone mineral density."
Basic
Scientific Rigor & Scholarly Dialogue
Clinical
Children and Adolescents
Surgery
Drugs
Food & Diet
Caloric and Dietary Restriction
Exercise & Physical Activity
Economics & Sociology
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Stigma
Policy Related
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- Webinar: A Recipe for Creativity in [Nutrition] Research: Cross-Fertilization, Credulity, Constraint, Contrarianism, Conversation, Courage.
- Plenty of Food Noise in Istanbul at ECO2026.
- On the Importance of Including Both Sexes in Animal Studies - Insights from Home-cage Monitoring.
- ECO2026: Rigor on Obesity and Eating Disorders.
- Framework for the Pharmacological Treatment of Obesity and Its Complications from the European Association for the Study of Obesity (EASO): 2026 Update.
- "A protein called HSL, long believed to simply release stored fat when the body needs energy, turns out to have a second job deep inside the nucleus of fat cells—helping keep those cells healthy and balanced. Even more surprising, people and mice missing this protein don’t become obese as expected."
- Obesity Pharmacotherapy: An Urgent Need for Progressing Science, Access, and Equity - JACC: Advances Expert Panel.
- Expert Reaction to an Analysis of Global Obesity Trends.
General
Announcements
Featured
Headline vs Study
Contrary or Null Findings
Basic
Scientific Rigor & Scholarly Dialogue
Clinical
Children and Adolescents
Surgery
Drugs
Food & Diet
Caloric and Dietary Restriction
Exercise & Physical Activity
Economics & Sociology
Epidemiology
Psychology & Neuroscience
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Ethics
Stigma
Policy Related
Intergenerational Effects
Ecology, Evolution, & Energetics
Methods
Mathematical and Quantitative
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General
Announcements
Featured
Headline vs Study
Contrary or Null Findings
Basic
Scientific Rigor & Scholarly Dialogue
- Article: Processed Meat Intake and Changes in Weight, Waist, Body Mass Index, and Fat Mass: Systematic Literature Review, Meta-Analysis, and GRADE Assessment of Cohort Studies Of Adults.
- Letter: Conceptual Confusion About “Processed Meat”.
- Reply to: Conceptual Confusion About “Processed” Meat.
- "The recent article by Xu et al. (1) concludes that creatine supplementation has positive effects on cognitive performance... However, certain aspects of the statistical approach have introduced a unit-of-analysis error."
- Article: The Effect of the Participatory Heat Education and Awareness Tools (HEAT) Intervention on Agricultural Worker Physiological Heat Strain: Results from a Parallel, Comparison, Group Allocated Study.
- Letter: Mislabeling and Inappropriate Analysis Render Interpretations from “The Effect of the Participatory Heat Education and Awareness Tools (HEAT) Intervention on Agricultural Worker Physiological Heat Strain: Results from a Parallel, Comparison, Group Randomized Study” Unreliable.
- Reply to: ‘Mislabeling and Inappropriate Analysis Render Interpretations from “The Effect of the Participatory Heat Education and Awareness Tools (HEAT) Intervention on Agricultural Worker Physiological Heat Strain: Results from a Parallel, Comparison, Group Randomized Study” Unreliable’.
- Correction: The Effect of the Participatory Heat Education and Awareness Tools (HEAT) Intervention on Agricultural Worker Physiological Heat Strain: Results from a Parallel, Comparison, Group Allocated Study.
Clinical
Children and Adolescents
Surgery
Drugs
Food & Diet
Caloric and Dietary Restriction
Exercise & Physical Activity
Economics & Sociology
Epidemiology
Psychology & Neuroscience
Differential Population Circumstances, Exposures, Outcomes, and Effects
Stigma
Policy Related
Intergenerational Effects
Ecology, Evolution, & Energetics
Methods
Mathematical and Quantitative
Commentary
General
Announcements
Featured
Headline vs Study
Contrary or Null Findings
Basic
Scientific Rigor & Scholarly Dialogue
Clinical
Children and Adolescents
Surgery
Drugs
Food & Diet
Caloric and Dietary Restriction
Exercise & Physical Activity
Economics & Sociology
Epidemiology
Psychology & Neuroscience
Differential Population Circumstances, Exposures, Outcomes, and Effects
Stigma
Policy Related
Intergenerational Effects
Ecology, Evolution, & Energetics
Methods
Mathematical and Quantitative
Commentary
General
Announcements
Featured
Headline vs Study
Contrary or Null Findings
Basic
Scientific Rigor & Scholarly Dialogue
- Retraction: Association between Vitamin D and Mortality Risk in Gout Patients.
- Letter: Stopping Spin at the Source: Learning from an Example in Obesity.
- Response To: “Stopping Spin at the Source: Learning From an Example in Obesity."
- PubPeer Comments On: The Effects of Omega-3 Supplementation on Stress, Anxiety, Depression, Sleep Quality, and Everyday Memory in Individuals with Psychological Distress: A Randomized, Double-Blind, Placebo-Controlled Trial.
- Retraction: The Effects of Omega-3 Supplementation on Stress, Anxiety, Depression, Sleep Quality, and Everyday Memory in Individuals with Psychological Distress: A Randomized, Double-Blind, Placebo-Controlled Trial.
- Controlling Confounding in Nutrition Research: Methodological Strategies, Software Implementation, and Reporting Guidelines. (pdf)
- Interview: Christopher Borgert on an Infamous Glyphosate Paper.
Clinical
Children and Adolescents
Surgery
Drugs
Food & Diet
Caloric and Dietary Restriction
Exercise & Physical Activity
Economics & Sociology
Epidemiology
Psychology & Neuroscience
Differential Population Circumstances, Exposures, Outcomes, and Effects
Stigma
Policy Related
Intergenerational Effects
Ecology, Evolution, & Energetics
Methods
Commentary
General
Announcements
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