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Contrary or Null Findings
- Thesis: "We also fail to confirm our choice substitution effect hypothesis between full-service and limited- service restaurants, finding counter-intuitive outcomes in one of the three cities studied as well as in our Placebo test city. These findings suggest that public infrastructure projects are not a panacea, as they don’t translate into immediate spillover effects to the food system."
- "A 300 kcal/kg difference in dietary energy [density] (2,750–3,050 kcal/kg) does not affect short-term (36–52 wk of age) egg production in Hy-Line W-36 laying hens."
- "Contrary to expectations, oral Lactobacillus communities were not enriched by the XOS-supplemented diet" [in mice].
- "Orthorexia nervosa and healthy orthorexia assessed by most measures, contrary to the expectations, had significant positive associations with psychological distress indicated by stress, anxiety, and depression."
- Thesis: Contrary to Our Hypotheses, BMI Was Not Significantly Associated with Overall Emotion Recognition Accuracy.
- No Evidence of Compensatory Changes in Energy Balance, Despite Reductions in Body Weight and Liver Fat, During Dapagliflozin Treatment in Type 2 Diabetes Mellitus.
- "...our analysis of a nationwide claims database found no evidence that SGLT2 inhibitors increase UTIs in Japanese patients with DM, regardless of sex or age."
- RCT: "The primary out-come was weight loss and weight loss maintenance in the respective phases....Overall, there was ...no significant differences between groups..." on weight loss.
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Headline vs Study
Contrary or Null Findings
- RCT: "Contrary to expectations, children in the control group demonstrated higher perceptions of intention (F(2, 84) = 4.838, p = 0.010) and effort (F(2, 80) = 3.473, p = 0.036) towards leisure-time physical activity at follow-up."
- "Contrary to prevailing hypotheses, weight changes in childhood is probably not a major explanatory mechanism linking early childhood adversity with later-life morbidity."
- "...contrary to our hypothesis, the study suggests that weight loss among overweight individuals did not result in higher life satisfaction."
- "Contrary to our hypotheses, higher greenness exposure was associated non-linearly with lower mean steps per minute after adjusting for confounders. We found higher levels of greenness were inversely associated with steps per minute."
- "With a limited number of studies, our data indicate that LCn-3 PUFA supplementation has no effect on muscle strength or functional abilities in older adults but may increase muscle mass..."
- "Contrary to our hypothesis, we find that the myoglobin gene from the minke whale, Balaenoptera acutorostrata, shows a low level of expression, only about 8% that of humans", that has implications for "Hypotheses regarding the mechanisms leading to these high myoglobin levels often invoke the induction of gene expression by exercise, hypoxia...".
- "Contrary to our hypothesis, we found almost no pattern in pore placement between clades, dietary groups or venom toxicity."
- "Contrary to our expectations, a 4-hr fast during the light photoperiod promotes a paradoxical increase in inter-animal variation in metabolic rate, physical activity, body temperature, glycemia, and glucose tolerance."
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Headline vs Study
Contrary or Null Findings
- "Despite strong statistical power, this study reveals no positive effect of the locally produced label on consumer WTP [willingness to pay]. These null results are contrary to most of the existing literature on this topic."
- RCT: No Significant Effect of an Online Self-Compassion Intervention for Weight Management Above and Beyond Weight Watchers.
- "Contrary to our hypothesis, increased hindgut starch fermentation did not induce an inflammatory response in this study" of cows.
- "Contrary to the body size and the dominance hypotheses, [flamingo] juveniles in better body condition were more likely to migrate than those in worse conditions, which opted for a residence strategy."
- "In conclusion, our study findings indicate some benefits of selenium on fasting insulin, and QUICKI [quantitative insulin sensitivity check index] compared with placebo, but elicits no effect on HbA1c, HOMA-IR, and FBS."
- "Healthy eating interventions could have favourable effects on child weight and risk of overweight and obesity, although there was little to no difference in BMI and BMI z-scores."
- Preprint: "Contrary to its role in Hbt. salinarum and Saccharolytic hyperthermophiles, TrmB does not act as a global regulator: it does not directly repress the expression of glycolytic enzymes, peripheral pathways such as cofactor biosynthesis, or catabolism of other carbon sources in Har. hispanica."
- Dissertation: "Contrary to my predictions, lizards showed no difference in macronutrient consumption between sexes."
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Headline vs Study
Contrary or Null Findings
- RCT: "Overall, the tested school-based health promotion strategies in this randomized clinical trial had a neutral [i.e., null] effect on the CVH of the adolescents."
- RCT: No Effect of a Low Dose of Omega-3 on the Lipid Profile of Pregnant Women with Obesity.
- RCT: No Effect of Multi-Strain Probiotic Supplementation on Metabolic and Inflammatory Markers and Newborn Body Composition in Pregnant Women with Obesity.
- Meta-analysis of RCTs: Medicinal cannabis for management of pain, sleep, and fatigue in cancer survivors "...had no effect ... appetite loss, weight loss..."
- "...contrary to our expectations, we observed weight loss during the lockdown."
- "These results suggest that, in mice, exercise has differential effects on aortic calcification, cardiac function, and skeletal bone mineral density."
- "Contrary to research on nondisabled children, we found that greater parental use of controlling dietary strategies was associated with lower BMI percentile in Latino children with IDD."
- "There was no difference in MVPA in overweight or obese (53.8%) vs. healthy weight (44.2%) adolescents (45.0 minutes [SD 16.6] vs. 43.1 minutes [SD 18.8])" in Type 1 diabetes.
- RCT: Changes in Polyunsaturated Fatty Acids During Treatment of Malnourished Children May Be Insufficient to Reach Required Essential Fatty Acid Levels.
- "In this sample of Victorian canteen menus, there was no evidence of associations of healthiness and pricing by school characteristics except for regional centres having the highest proportion of ‘black’ (banned) items compared with all other remoteness categories examined."
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Featured
Headline vs Study
Contrary or Null Findings
Basic
Scientific Rigor & Scholarly Dialogue
Clinical
Children and Adolescents
Surgery
Drugs
Food & Diet
Caloric and Dietary Restriction
Exercise & Physical Activity
Economics & Sociology
Epidemiology
Psychology & Neuroscience
Equity and Disparities
Stigma
Policy Related
Intergenerational Effects
Ecology, Evolution, & Energetics
Methods
Commentary
General
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