Obesity and Energetics Offerings

Featured

• Eleventh and 12th-Grade Students from an Economically Disadvantaged Charter School Express High Interest in Food/Cooking Education.
• Modeling the Circadian Dynamics of Resting Energy Expenditure for the Built Environment.
• Time-Restricted Feeding Extends Healthspan in Both Sexes and Lifespan in Male C57BL/6 J Mice.
• Definitions of Arginine Availability: A Critical Metabolic Marker of Physiological Processes.

Headline vs Study

• Headline: What You Eat May Be Shaping Your Mental Health - Especially If You're a Woman.
• Study: Self-Reported Dietary Inflammatory Index Is Associated with Reported Depressive Symptoms in Men and Women, with No Formal Test to See Whether It Is Especially for Women.

Contrary or Null Findings

• "Omega-3 supplementation may be associated with accelerated cognitive decline in older adults... These findings challenge the prevailing view of omega-3 as uniformly beneficial and highlight the need for a cautious reassessment of its widespread use for cognitive protection."
• "...unlike in C. elegans, WWP1 is not required for CR-induced longevity in mammals..."
• RCT: "The linear mixed-effects models using period-level change scores showed no statistically significant treatment effects for steps, sleep time, sedentary time, lightly active time, or active time" in "Feasibility of remotely delivered Tai Chi on older adults’ 24-hour movement behaviors."
• RCT: "...no significant between-group differences were detected..." in "The Effect of Low Glycemic Load Diet on Central Obesity and Lipid Related Metabolic Abnormalities in T2DM Patients Is Comparable to That of Energy-Restricted Diet..."
• RCT: No Significant Between-Group "Effects of Continuous vs. Intermittent Caloric Restriction on Fat Loss."
• RCT: "Sakurajima radish does not appear to improve endothelial function in patients with MetS within the constraints of this short-term crossover design."
• RCT: "The intervention improved participants' nutrition-related KAP [knowledge, attitude, and practice] scores but did not increase the intake of immune-enhancing nutrients, except for vitamin E."
• RCT: "The primary outcome, subjective fatigue assessed using the web-based daily log, was not significantly different between groups during the summer study period" in "Combined NY1301 and DDMP on Sleep and Autonomic Function in Summer".

Basic

• Nitrate-Sialin2 Axis Couples ER-Mitochondrial Calcium Signaling with Fatty Acid Metabolism to Drive White Adipose Browning.
• Independent and Synergistic Effects of Maternal and Paternal Obesogenic Diets on Offspring Early-Life Outcomes in the Rat.
• Genome-Wide DNA Methylation Changes Induced by High-Fat Diet and Methyl Donor Supplementation in Female Lupus Models.
• Dietary Omega-6 Lipids Promote Post-Injury Aberrant Bone Formation in Obesity.
• Time-Restricted Feeding Counters Brown Adipose Tissue Whitening and Inflammation in Obese Mice Under Chronic Light Exposure.

Scientific Rigor & Scholarly Dialogue

• BITESIZE: Omega-3 Supplements and Cognitive Decline? Here’s the Full Story.
• Perspective: Interpreting Ultra-Processed Food Trial Evidence: Evidentiary Limits, Reporting Practices, and Policy Relevance.
• Believing Is Seeing: Effects of Food Labeling in Chile.
• Review: Concerns Regarding the Standard Deviation of Individual Responses for Assessing Treatment Response Heterogeneity | Journal of Applied Physiology.
• Letter: Misconceptions About Variance Comparisons for Exploring the Presence of Treatment Response Heterogeneity in Randomized Controlled Trials | Journal of Applied Physiology.
• Reply to Atkinson et al. | Journal of Applied Physiology.

Clinical

• RCT: Time-Restricted Eating Promotes Weight Loss and Favorable Changes in Adipose in Obesity.
• RCT: Multidimensional Effects of Personalized Exercise Intervention in Type 2 Diabetes.
• Meta-Analysis: Cardiovascular Outcomes of Glucagon-Like Peptide-1 Receptor Agonists in Patients Without Obesity.

Children and Adolescents

• Disparities of Children’s Obesogenic Environments in Louisiana.
• Observed Mealtime Interactions, Meal Healthfulness, and Childhood Obesity Among Low-Income Families.
• Meal Replacement Therapy for Metabolic Dysfunction-Associated Steatotic Liver Disease in Adolescents with Severe Obesity.
• Review: Childhood Obesity: Epidemiology, Risk Factors, Prevention, and Emerging Treatment Strategies.
• Parental Communication with Children around Obesity Management Medications, Weight Loss, and Health Behavior Change.
• Prevalence of Preclinical and Clinical Obesity Among US Children and Adolescents Aged 5 to 18 Years: NHANES 2017-2023.

Surgery

• Global Variability in Children and Adolescent Metabolic Bariatric Surgery Guidelines: A Worldwide IFSO Survey.
• Divergent Colorectal Cancer Risks Following Metabolic Bariatric Surgery: Anatomical Remodeling and the Genotoxic Microenvironment.
• Inguinal Hernia Repair Utilizing Laparoscopic Techniques in People with Obesity.
• Systematic Review: What Is Weight Loss After Bariatric Surgery Expressed in Percentage Total Weight Loss (%TWL)?
• Case report: Multilevel Endoscopic Thoracic Spine Surgery in a Patient with Obesity.

Drugs

• Physical Fitness with Exercise and GLP-1 Receptor Agonist Treatment Alone or Combined After Diet-Induced Weight Loss.
• RCT: Survodutide Once Weekly for the Treatment of Adults with Obesity.
• RCT: Treatment with 9-mg Mazdutide for Weight Reduction in Chinese Adults with Obesity.
• Zealand Pharma Announces Boehringer Ingelheim's Survodutide Phase III Trial in People Living with Obesity Showed Targeted 34% Visceral and 63% Liver Fat Reduction, While Minimizing Lean Mass Loss in Pre-Specified Analysis.
• Meta-Analysis: Placebo Response on the Weight Change and Its Influencing Factors in Overweight or Obesity with or Without Diabetes.

Food & Diet

• Review: Spices for Targeting the Gut Microbiome to Improve Cardiometabolic Health.
• Semaglutide-Induced Loss of Skeletal Muscle Mass Is Blunted by Co-Administration of Ketone Esters.
• Review: The Purpose of Food Processing and Ultra-Processed Food: The Potential, Pitfalls and Path Forward for Public Health.
• Meta-Analysis: "Higher adherence to the MD [Mediterranean diet] is associated with a reduced risk of all-cause mortality".
• Meta-Analysis: Impact of Tomatoes and Tomato-Derived Products on Obesity and Cardiometabolic Health.
• Meta-Analysis: Late Eating and Obesity.

Caloric and Dietary Restriction

• When Caloric Restriction and Exercise Join Forces: Counteracting the Detrimental Effects of Obesity on the Musculoskeletal System.
• Trace Element Dynamics Following Low-Calorie Formula Diet and Their Association with Glycaemic Traits.
• RCT: Very Low Calorie Diet Versus Conventional Energy-Restricted Diet for Weight Loss Before Bariatric Surgery.
• Review: Caloric Restriction Rejuvenates Aged Adult Stem Cells: From Mechanisms to Interventions.

Exercise & Physical Activity

• RCT: Myosin Light Chain Proteins Cooperatively Promote Sarcomere Growth in Fast-Twitch Muscle.
• RCT: Prunes Preserve Cortical Density and Estimated Strength of the Tibia in Postmenopausal Women.
• Exercise Attenuates Obesity-Related Cognitive and Sleep-Circadian Dysfunctions by Attenuating Neuroinflammation Via JAK/STAT in Sex and Age Specific Manner.
• Systematic Review: Digital Health Interventions for Physical Activity in Children and Adolescents with Obesity.
• Longitudinal Associations between Physical Activity-Sedentary Time Balance and Internalizing/Externalizing Problems in Children.

Economics & Sociology

• GLP-1 Therapy and the Reshaping of Socioeconomic Gradients in Health.
• Systematic Review: Obesity, Employment, and Economic Productivity in Europe.

Epidemiology

• Associations between Screen Time and Dietary Intake Among Early Adolescents: A Prospective Cohort Study.
• Early-Onset Obesity and Heart Failure Burden Independent of Cardiometabolic Risk Factors.
• Association between Metabolic Heterogeneity of Obesity and Biological Aging Among Adults: A Population-Based Study.
• Meta-Analysis: Obesity Is Associated with Suppressed Bone Turnover.

Psychology & Neuroscience

• Systematic Review: Effectiveness of Internet-Delivered Cognitive Behavioural Therapy in Improving Weight-Loss and Psychosocial Well-Being Among Adults with High BMI.
• Anti-Obesity Medications and Cognitive Disorder Risk: A Discrepancy between RCTs and Real-World Evidence.
• Depression Meets Obesity: Co-occurrence Patterns, Temporal Trends and Socioeconomic Correlates Across 199 Countries and Territories.
• Commentary: Your Brain on a GLP-1: What We Know About the Mental Side.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• A Cross-Sectional Investigation of Relationships between Food Pleasure and Worry, Eating Behaviors, and Cultural Attributes Among Mexican American Adults.
• Preprint: Twenty-Year Trends in Adolescent Overweight and Obesity and Socioeconomic Inequalities.
• Food Insecurity, Dietary Quality, and Cardiovascular Risk Among Early Childhood Cancer Survivors.
• Associations between Race, Healthcare Coverage, Adiposity, and Cardiometabolic Risk Among Underserved U.S. Adolescents.

Ethics

• Systematic Review: BMI and Weight-Based Eligibility Criteria in Drug-Development Trials: Ethical Analysis.

Stigma

• Psychometric Validation of the Weight and Emotions Scale (WES) in Adults with Obesity or Overweight.
• Commentary: Obesity Stigma: Is Art History the Fix?
• Internalized Weight Stigma and Obesity-Related Quality of Life in Adults with Obesity or Overweight.

Policy Related

• From a Policy Perspective, Is Sugar the New Tobacco?
• Commentary: New Federal Food Policies Will Affect Food Labeling, Reformulation, and Healthfulness.
• Integrated Food Policy and Child Obesity.
• Commentary: A Framework for Developing Intake and Use Guidance for Dietary Supplement Bioactives.
• Evidence-Informed Guidance for the Clinical Use of Oral Semaglutide in Obesity Management.

Intergenerational Effects

• Genetic and Environmental Influences on Educational Disparities in Adult Weight Change: An Individual-Based Pooled Analysis of 11 Twin Cohorts.
• Long-Term Effects of Exercise During Pregnancy on the Metabolic Health of Mothers with Overweight/Obesity and Their Offspring.

Ecology, Evolution, & Energetics

• Energy Requirements: The Case for the Factorial Model.
• Renal Gluconeogenesis: A Key Metabolic Hub in Health and Kidney Disease.

Methods

• Systematic Review: How Have Researchers Estimated the Impact of Excess Weight on Mortality?
• Systematic Review: Validated Food Quantification Aids for Dietary Assessment.
• Temporal External Validation of a Customized Fetal BMI Percentile Model for Neonatal Nutritional Status Assessment.
• Assessment of Body Composition in Severe Obesity: Agreement between Multifrequency Bioelectrical Impedance Analysis and DXA and Contribution of Raw Impedance Data.

Commentary

• Podcast: Dominic D’Agostino Discusses Advances in Ketogenic Metabolic Therapy and Hyperbaric Oxygen Therapy.
• Podcast: Brain Lipidology: Understanding APOE, Cholesterol Homeostasis, Alzheimer’s Disease Risk, and the Effects of Lipid-Lowering Therapies on Brain Health | Tom Dayspring, M.D.
• "Elecoglipron, a novel oral GLP-1 receptor agonist (RA), led to significant reductions in A1c and moderate reductions in body weight in people with type 2 diabetes (T2D), according to the results of the phase 2b SOLSTICE trial."
• Podcast: Female Training, Hormones & Nutrition: Fact Vs. Fiction | Dr. Lauren Colenso-Semple.
• Time-Restricted Feeding Puts Mouse Healthspan on the Clock.
• Eos SENOLYTIX Presents Best-In-Class Preclinical Body Composition Data Highlighting Unique Muscle Mass Gains with MitoXcel™ Geropeptide PTC-2105 at the Sachs 2nd Annual Obesity & Cardiometabolic Innovation Forum.
• Implicit Bias Inferring Causality for Obesity Medicines.
• Interaction of Physical Activity and Gut-Brain Axis: Relevance for Obesity.

General

• Podcast: Public Health Misinformation & Communication: How to Build Trust for Behavior Change - Dr. Jessica Steier.
• First in Situ Observations of the Goblin Shark Mitsukurina owstoni.
• Podcast: Derisking Phase II Clinical Trials in HF.
• Ameliorating Calcium Homeostasis Improves Longevity and Healthspan in Progeroid and Naturally Aged Mice.
• P21-Senescent Cells Drive Pancreatic Islet Dysfunction Through Targetable Paracrine Signaling in Type 2 Diabetes.
• Revealed: How Venus Flytraps Snap Shut with Astonishing Speed.
• Podcast: What’s the Future of Gene Editing?
• Ferroptosis Susceptibility in Hippocampal Neural Precursor Cells Influences Neurogenesis and Memory Across Aging.
• Humans Outperform AI at This Highly Rigorous Mathematics Test.

Video & Audio

• Podcast: Why Amylin May Be the Most Important Weight Loss Hormone You've Never Heard Of.
• Podcast: Public Health Equity | Stats + Stories Episode 388.
• Exploring the Benefits of Creatine for Aging Adults Grappling with Loss of Muscle Mass.

Announcements

• Texas Children’s Hospital and Baylor College of Medicine Researcher Awarded Up to $17.25 Million to Join an International Autism Research Collaborative.
• Watch the 2026 State of the Science Address - Marcia McNutt of the National Academy of Sciences.

Featured

• The Anabolics are Coming: RCT - Apitegromab for Lean Mass Preservation During Tirzepatide-Induced Weight Loss.
• Tracking Changes in Body Composition in Athletes: Are Rapid Four-Compartment Models Valid?
• Podcast: Ozempic, Yo-Yo Diets & the Science of Weight Loss, with Dr. David Allison.
• Drosophila Disengage Systemic Protein Storage as an Evolutionary Response to Chronic Larval Malnutrition.
• Ultraprocessed Foods and Obesity: Interpreting the Evidence.
• Systematic Review: Evaluating the Safety of Creatine Monohydrate in Adolescents.

Headline vs Study

• Headline: Could a Gut Microbe Help Reduce Weight Regain After Dieting? New Study Suggests It Might.
• RCT: Pasteurized (i.e., Dead and Processed) Akkermansia muciniphila Muc^T Supplement Resulted in Better Weight Loss Maintenance in People with Overweight and Obesity.

Contrary or Null Findings

• RCT: "A 24-week intervention with freeze-dried blueberries had no effect on serum p-tau181 and serum NFL in older adults."
• RCT: "In ELBW infants, providing an additional 1 g/d of parenteral amino acids for 5 days after birth has little to no effect on survival without neurocognitive impairment at school age and may have adverse effects on strength and psychosocial functioning."
• Meta-Analysis: "Vitamin B12 supplementation (alone or when supplemented with other micronutrients) in children may have little to no effect on growth (i.e. height/length), cognitive function (e.g. attention), development outcomes (e.g. motor skill development), or anaemia, compared to placebo, no intervention, or the same supplements without vitamin B12."
• RCT: No Apparent Impact of a Prenatal Nutrition Package with Balanced Energy Supplementation on Gestational Weight Gain in Amhara, Ethiopia.
• "Contrary to our hypothesis, higher BMI was associated with poorer CAT and cognitive performance among participants with HIV."
• "Results are contrary to the established links between executive function and time spent outdoors..."
• Umbrella Review: "Testosterone therapy improved lean muscle mass and strength without adverse effect in older men...There was no effect demonstrated on major cardiovascular events or all-cause mortality."
• "...high-intensity systematic training significantly decreases Body Mass Index and significantly increases osteocalcin levels, whereas other training types had no effect [association]."

Basic

• 15-PGDH Inhibition Promotes Muscle Repair and Strength Recovery During GLP-1 Receptor Agonist-Induced Weight Loss.
• Effects of Changes in Fat Metabolism by Particulate Matter on Endometrium and Infertility.
• STAU1 Fine-Tunes Adipose Thermogenesis by Regulating Ucp1 mRNA Stability.
• Targeting Hypothalamic SIK3 to Promote Weight Loss and Improve Glycemic Control in Mice.

Scientific Rigor & Scholarly Dialogue

• Article: Evaluating Agreement between Individual Nutrition Randomised Controlled Trials and Cohort Studies - a Meta-Epidemiological Study.
• Letter: Concordance between Nutritional Cohorts and Randomized Trials: Biological Confirmation or Statistical Consequence? A Re-Analysis of Stadelmaier et al.
• Response to: Matters Arising in Relation to “Evaluating Agreement between Individual Nutrition Randomised Controlled Trials and Cohort Studies - A Meta-Epidemiological Study”.

Clinical

• Patient Preferences for Pharmacological Treatments for Obesity: The VOICE Study.
• Association of Post-Oral Glucose Tolerance Test Hypoglycaemia with Clinical Features, Incident Diabetes and Mortality.
• Clinical Intervention Following Detection of Incident Diabetes Within a Large Psychiatric Service System: A Chart Review Study.

Children and Adolescents

• Systematic Review: Adolescent Obesity and Risk of Serious Chronic Morbidity and Mortality in Young Adulthood.
• Healthy Lifestyle Synergy and Its Association with Overweight and Obesity Among Parent-Child Dyads.
• Meta-Analysis: Childhood Obesity and Age-Related Diseases.
• What Is Driving Energy Intake After Weight Loss? A Longitudinal Mediation Analysis in Adolescents with Obesity.
• Relationship between Triglyceride-Glucose-Derived Obesity Indices and NAFLD in Adolescents.

Surgery

• Metabolic and Bariatric Surgery Vs. Dietary Counseling in Adults with Severe Obesity: Risk of De Novo Malignancy in a Propensity-Matched Multicentered Real-World Analysis.
• ‘Bridging Therapy’ as a Preoperative Strategy for Bariatric Surgery in Super-Super Obesity: A Report of Two Cases.
• Scoping Review: The Application of Large Language Models in Bariatric Surgery.
• Tirzepatide for Recurrent Weight Gain After Bariatric Procedures: Real-World Evidence of Efficacy and Safety.
• Bariatric Surgery in Adolescents with Obesity: Weight and Cardiometabolic Outcomes - Real-World Data.

Drugs

• Glucagon-Like Peptide-1 Receptor Agonists and Cardiovascular Events in Adults with Obesity and Autoimmune Disease: A Target Trial Emulation.
• Scoping Review: Do GLP-1 Receptor Agonists Sabotage Fat Grafts? GLP-1 Receptor Agonist Effects on Adipocyte Biology and Implications for Autologous Fat Transfer.
• Semaglutide Slows Epigenetic Aging in RCT of HIV-Associated Lipohypertrophy.

Food & Diet

• Attenuation of Adaptive Thermogenesis by a Culinary Dose of Red Pepper During 24-Hour Negative Energy Balance.
• Chronic High-Fat Diet Does Not Alter Overall Cancer Incidence in Trp53R270H/+ Mice.
• Whole-Body Protein Balance During Arctic Military Training Is Unaffected by Dietary Essential Amino Acid or Energy Density.
• Anti-Obesity Mechanisms of Adzuki Bean Saponin.

Caloric and Dietary Restriction

• Dietary Energy Level Modulates Dietary Silver Nanoparticle Toxicity in Zebrafish (Danio rerio): Growth, Oxidative Stress, Fatty Acid Composition, and Bioaccumulation.
• Time-Restricted Feeding Extends Healthspan in Both Sexes and Lifespan in Male C57BL/6 J Mice.
• Untargeted Metabolomics Reveals Effects of Calorie Restriction on Skeletal Muscle in Older Female and Male Rats.
• RCT: 12 Weeks of Caloric Restriction with a Novel Diet in Overweight Cats with Diabetes Mellitus.
• Do the Effects of Early Time-Restricted Eating Vary by Cardiometabolic Phenotype, Age, Sex, or Race?

Exercise & Physical Activity

• Preprint: Ageing Blunts the Phospho-Proteomic Response to Resistance Exercise in Humans.
• Exercise-Induced Changes in Systemic Inflammatory Biomarkers in Populations with Overweight or Obesity.

Economics & Sociology

• The Role of Social Food Infrastructure in Addressing SNAP Participation Gaps: Evidence from Linked Administrative and Ground-Sourced Data.
• Projecting the Macroeconomic Burden of Type 2 Diabetes Mellitus Attributable to High Body-Mass Index in Southeast Asia.
• Abstract: Associations and Interactions of Genetic Predispositions for Taste Preferences and Socioeconomic Status with Hyperpalatable Food Intake.

Epidemiology

• Prepregnancy BMI in Ontario from 2012 to 2022.
• Socioeconomic Development, Longevity and Prevalence of Obesity and Overweight.
• Prevalence and Associated Factors of Obesity Among the Staff of the University Hospital Center of Owendo.
• Dietary Intake of Polybrominated Diphenyl Ethers (PBDEs) and the Risk of Obesity in the French E3N Cohort.
• Review: Epidemiology of Cardiometabolic Multiple Long-Term Conditions.

Psychology & Neuroscience

• Obesity and Depressive Disorders Among U.S. Adults with Disabilities: The Mediating Role of Healthcare Access and the Moderating Effect of Physical Activity.
• Deletion of Neurosecretory Proteins GL and GM Drives Dual Anti-Obesity Effects Via Appetite Suppression and Enhanced Energy Expenditure.
• Adipose Tissue as a Systemic Modulator of Brain Aging: Mechanistic Links between Metabolism, Inflammation and Neurodegeneration.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Association of Lifestyle Behaviours and Socioeconomic Disparities with Overweight and Obesity Among School-Aged Children and Adolescents: A Population-Based Cross-Sectional Study.
• Attenuating the Mortality Risk of Socioeconomic Deprivation in Type 2 Diabetes: Minimum and Compensatory Physical Activity Estimates.

Stigma

• Interventions to Reduce Implicit Weight Bias: A Focus on Mechanisms and Individual Differences.
• Weight Stigma in Cancer Care.
• Internalized Weight Bias Is Associated with Dysregulated Affect and Binge Eating in Daily Life Among Adults of High Body Weight with and Without HIV.

Policy Related

• Examining the Relationship between Meal Costs and the Redemption of the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) Benefits in Oklahoma: An Instrumental Variables Method.
• Reducing Unhealthy Consumption While Balancing Health Inequality: The Dual Effects of Explicit Sugar Taxes.

Intergenerational Effects

• Role of Parental Characteristics and Feeding Practices in Childhood Obesity.
• Preprint: BMI Decline and Cognitive Trajectories in Mild Cognitive Impairment: The Role of Maternal History of Alzheimer's Disease.

Ecology, Evolution, & Energetics

• Chapter: Foraging Ecology, Nutrition, and Energetics.
• Nutrient-Driven Histone Acetylation Underlies Energy Storage and Mobilization.
• Auditory Prey Specialization Sustains Fat-Deposition-Free Winter Survival in Morpho-Acoustically Adapted Bats.
• Strong Pleiotropic Effects of a Fatty Acid Synthase on Energy Storage, Sexual Signalling and Reproduction in a Parasitic Wasp.

Methods

• A Deep-Learning Framework Reveals Whole-Body Perturbations at Cell Level.
• Optimizing Machine Learning Models for Obesity Risk Prediction Through Hyperparameter Tuning.
• Reducing Bias and Enhancing Equity in AI-Enabled Precision Nutrition: Addressing Measurement Error Across Wearables, Multiomics, and Dietary Data.
• Carbon Isotope Ratios as Biomarkers for Added Sugar Intake: Fundamental Limitations That Constrain Valid Application.
• Construction and Validation of a Machine Learning Model to Predict the Sarcopenic Obesity Population.
• Examining the Invariance of a Common Household Food Insecurity Measure Across Various Adult and Child Characteristics.

Commentary

• A Global Commitment to Addressing Chronic Liver Disease.
• Podcast: Are Food Preservatives Raising Your Blood Pressure? A New Study Explained.
• What the Ultra-Processed Foods Debate Still Gets Wrong.
• Shouldn't Where We Get Fat (and When) Tell Us Something About Why?
• The Evidence Against 10,000 Steps for Weight Loss Exercise Has Important Health Benefits, but Diet Drives Meaningful Weight Change.
• Dairy Byproducts Hold Promise for Human Nutrition.
• Biomea Fusion Presents New Clinical and Translational Data for Icovamenib at the American Diabetes Association (“ADA”) 86th Scientific Sessions and Announces Expansion of Ongoing Phase I BMF-650 Study.
• Is It Time to Reassess the View of Linoleic Acid and Inflammation?
• Why Should Nutrition Research and Innovation Be Integrated with Environmental Science?
• Benefits Beyond Weight Loss with Survodutide.

General

• AI-Assisted Teams Outperform AI-Led Teams but Not Human-Only Teams in Assessing Research Reproducibility in Quantitative Social Science.
• Preprint: Automating Reproducibility Checks Using Large Language Models.
• Podcast: Peakspan: Defining and Extending the Boundaries of Human Performance.
• Podcast: The Measure of Motion with Dr. Christine Harper.
• Why Psychopathology Researchers Should Avoid Studying One Mental Disorder at a Time: An Intergenerational and Developmental Evidence Base for Understanding ‘p’.
• Data Sharing in Stepped-Wedge Cluster RCTs: Suboptimal Data Availability Despite “Data Available upon Request”. (pdf)
• Data Available upon Request - Time to End the Charade?
• From Replication Crisis to Research Rigor: What Applied Sport Science Can Learn from Psychology.
• OLD DOG - Validating the Dog as an Animal Model for Human Aging Studies.
• Does the Biodiversity of Urban Green Spaces Impact on Human Health.

Video & Audio

• Podcast: Obesity, Liver Disease, and the Patient Voice.
• Podcast: Ketones - Aitor Viribay Energy Series.

Announcements

• Postdoctoral Fellowship Positions - USDA ARS Children’s Nutrition Research Center.
• Jamie Justice: The Woman Behind the World’s Biggest Longevity Competition.

Featured

• Impact of Prematurity on Nutrient Signaling and Protein Synthesis in Skeletal Muscle.
• Male Obesity Causes Adipose Mitochondrial Dysfunction in F1 Mouse Progeny Via Let-7-DICER Axis.
• Validation of Digital Anthropometric Measurements During Pregnancy: A Longitudinal Study.
• Podcast: The Science of Getting Science Right w/ Dr. David Allison.

Headline vs Study

• Headline: New Research Finds Link between Obesity and Breast Cancer Risks.
• Press Release: Obesity May Influence How Breast Cancer Spreads.
• Study: Transcriptomic Differences in Breast Cancer Samples from Women with and without BMI-Defined Obesity. Breast Cancer Risks nor Spreading Studied.

Contrary or Null Findings

• RCT: No Differential Effect (or Differential Lack of Effect) of Mediterranean and Healthy Eating Guideline Interventions on the Dietary Inflammatory Index in Rheumatoid Arthritis.
• RCT: "At habitual dietary protein intakes -0.9 g/kg body mass/d, further rBLG or WHEY supplementation did not influence muscle recovery or iMyoPS rates, suggesting that protein supplementation, at the intakes studied, may have limited efficacy as a tool to enhance muscle recovery and remodeling from damaging exercise."
• RCT: "Disclosure of obesity-related genetic information with tailored advice did not improve weight outcomes overall..."
• RCT: "Wild blueberry effects on postprandial glucose and appetite hormone responses were evident at anthocyanin doses of 300 mg and above but did not impact other outcomes in healthy adults."
• RCT: "A multicomponent mHealth sedentary reduction intervention led to changes at 5M in sit-to-stand transitions but was not effective in reducing sedentary time in adults who had undergone TKR..." (pdf)
• RCT: "A combination of heatwrap and exercise was not statistically superior to heatwrap alone or a sham heatwrap in the treatment of acute LBP, contrasting with the existing literature and guidelines."
• "Ultimately, biochar had limited and variable effects on reducing Pb ingestion risks in the studied vegetable agrisystems, which suggests that its remediation potential in urban agrisystems is context-dependent and may offer limited protection for growers and consumers in soils with elevated pH and organic matter."
• "Consumption of Energy drinks was found to be a risk factor, while caffeinated drinks had no effect" on overactive bladder.

Basic

• Gut Microbiota Alteration Contributes to Bone Marrow Mesenchymal Stem Cells Connexin43 Response to High-Fat Diet Induced Obesity in Mice.
• Effects of Exercise on PVAT-Derived Exosomes in the Modulation of Vascular Function in Obese Mice.
• Phosphomannomutase 1 Restrains Adipose Thermogenic Programming Via Inosine Signaling.
• Functional Rice Enriched with Resistant Starch Ameliorates Metabolic Dysregulation in High-Fat Diet-Induced Obese Mice.
• Biobank Analysis Reveals More Than 88,000 Genetic Associations with Metabolic Traits.
• Review: Hypothalamic Obesity.

Scientific Rigor & Scholarly Dialogue

• On Health and Understanding: Signature Threats to Signal in an Age of Noise.
• Editorial: Inconvenient for the Investigator but Convenient for Science: Trial Registration in the American Journal of Clinical Nutrition.
• Article: Reframing Basic Experimental Studies in Humans - Implications for Nutrition Science.

Clinical

• Validation of the Obesity Lifecycle Model Built to Assess the Cost Effectiveness of Novel Therapies in the Management of Obesity.
• Statins and Risk of Cardiovascular Disease: Emulating a Primary Prevention Trial in Breast Cancer Survivors.
• Cardio-Obstetrics Care: Challenging Scenarios in Heart Failure and Future Directions.

Children and Adolescents

• Diagnostic Performance of Obesity Indices for Predicting Hypertension Among Children Aged 6-13 Years in Polokwane.
• Letter: No Significant Change in Childhood Obesity.
• The Impact of Maternal Metabolic Flexibility During Gestation on Infant Adiposity in Individuals with Obesity.
• Prevalence, Trends, and Projections of Overweight and Obesity Among Children and Adolescents in Indonesia.
• Perinatal Outcomes in Pregnancies with Type 2 Diabetes and Weight Gain Less Than 5 Kilograms.

Surgery

• Cefazolin Surgical Prophylaxis in Obesity: A Body Composition-Driven Population Pharmacokinetic Approach.
• Metabolic and Bariatric Surgery in Mild Obesity.

Drugs

• Commentary: Incretin Therapies, Nutrition and Food Insecurity in the UK.
• The Evolving Landscape of Obesity Pharmacotherapy.

Food & Diet

• Associations Among Pork Intake, Weight-Loss, and Diet Quality Outcomes in a Commercial Weight-Management Program.
• RCT: Very Low-Carbohydrate Ketogenic Diet in Treatment-Naïve Women with Endometrial Cancer and Overweight.
• Tradeoffs between Convenience, Cost, and Healthy Eating Index for Menus Varying in Ultra-Processed Foods.
• The Whey of the Future: Is RBLG a New Player Within Protein Nutrition?
• Rethinking Dietary Fat for the Aging Brain: The Roles or Ketosis and Fat Quality in Cerebrovascular Aging and VCID.
• Meta-Analysis of RCTs: Long-Term Effects of Plant Vs. Animal Protein Supplementation on Body Composition, Muscle Strength, Physical Performance, and Cardiometabolic Risk Factors in Adults.
• Associations between Sugar-Sweetened Beverage Intake and Metabolic Syndrome Among Postmenopausal Black Women with Obesity and a Family History of Breast Cancer.

Caloric and Dietary Restriction

• RCT: Achieving Diabetes Remission Through Dietary Intervention.
• Self-Selected Dietary Intake and Association with Achieved Caloric Restriction.
• An In-Depth Analysis of the Molecular Changes Induced by Short-Term Calorie Restriction Before Living Kidney Donation.

Exercise & Physical Activity

• Physical Activity and Life Expectancy: A Life-Table Analysis.
• Meta-Analysis: Effects of Physical Activity-Based Digital Health Interventions on Psychological Outcomes in Adolescents with Overweight or Obesity.

Economics & Sociology

• Preprint: Weight Management Practices, Views, and Experiences Among Adults with Low Socioeconomic Position and Obesity.
• Dietary Inflammatory Index Mediates the Relationship of Social Determinants of Health with Blood Pressure and Obesity in the United States.
• Obesity and the Experienced Cultural, Economic, and Climate Variations Among Immigrants to High-Income Countries.
• Clinical and Economic Burden Among People with Knee Osteoarthritis and Obesity in the United States: A Retrospective Analysis.

Epidemiology

• National Prevalence of Clinical Obesity by BMI Class.
• Comparing Multiple Definitions of Obesity in a Large Nationwide Health Program.
• Association between Obesity and Abdominal Aortic Aneurysm: Complex Interactions between Waist Circumference and BMI.
• The Association between GLP-1R Expression and Cardiovascular-Kidney-Metabolic-Related Diseases in a Population without Diabetes or Obesity Population.
• Sarcopenic Obesity and Dementia Risk: Primary Associations and Landmark Analyses of Muscle Strength and Body Composition Trajectories.

Psychology & Neuroscience

• Impaired Boundaries, Sense of Self, and Personal Control: The Lifelong Trajectory of Co-Occurring Obesity and Adverse Childhood Experiences for Adult Women.
• Insomnia and Daytime Sleepiness Identify Distinct Behavioural Phenotypes of Binge Eating and Mood in Clinical Obesity: The MOCC Cohort (n = 2,016).
• Suicidality as a Potential Risk and Therapeutic Target During Widespread GLP-1 Receptor Agonists Use: Implications of Inflammation.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Socioeconomic Disparities and Nutritional Aging: How Food Insecurity and Financial Hardship Accelerate Health Decline in Older Adults.
• Preprint: Urban Environment and Socio-Economic Inequalities in Childhood Excess Weight: A Cross-Sectional Study in Geneva, Switzerland.
• Racial Disparities in Severe Maternal Morbidity During the COVID-19 Pandemic.

Stigma

• Social Perceptions of Weight Loss with Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists.
• RCT: Using Theatre to Tackle Weight Stigma in Primary Care: A Participatory Study on Empathy and Professional Awareness.

Policy Related

• Thesis: Do Cash Transfer Programs Work? Evidence from Peru’s Juntos Program on Child Outcomes Program on Child Outcomes.
• "The 2025-2030 Dietary Guidelines for Americans are associated with higher land, water and nitrogen use, and greenhouse gas emissions."
• Assessing Europe's Policy Readiness to Confront the MASLD/MASH Public Health Threat.
• Ending the Chronic Liver Disease Public Health Threat: Systemic Challenges Through the Patient Lens.
• Examining Public Support for Food Marketing Policy Among Adults in Canada.

Intergenerational Effects

• The Role of Fathers in the Intergenerational Transmission of Obesity.
• Scoping Review: Influence of Paternal Preconception Health on Miscarriage and Time to Pregnancy.

Ecology, Evolution, & Energetics

• Telomere Length in Metabolic Syndrome: Mechanisms, Epidemiology and Clinical Implications.

Methods

• Unsupervised Machine Learning for Scientific Discovery: Workflow and Best Practices.
• Precision Obesity Medicine: A Translational Perspective on Epigenetics, the Gut Microbiome, and AI-Assisted Multi-Omics Integration.
• Body Composition Phenotyping of Obesity in Children Aged 6-18 Years: Multi-Strategy Clustering and Interpretable Machine Learning.
• Mobile Applications for Body Composition Estimation: Functionality, Current Findings, and Future Directions.
• Skinfolds Measurement Protocols and Standards: A Narrative Review.

Commentary

• Podcast: Diet and Exercise Recommendations for Patients Taking GLP-1 Receptor Agonists.
• Podcast: Intense Exercise & Potential Heart Damage (aka Athlete's Heart).
• Podcast: Creatine for Muscle, Bone, Brain & Longevity (Plus Caffeine, Dosing, and Safety) with Dr. Darren Candow.
• Podcast: Dr. Mikhail Kosiborod Discusses the Evolving Science and Cardiometabolic Diseases Associated with Obesity.
• Podcast: The Silent Fuel Crisis Starving Your Brain | Dr Stephen Cunnane.
• New AI Model Finds a Cheaper Path to Healthier Eating.

General

• Podcast: Creatine Supplementation in the Management of Osteosarcopenia.
• Misinformation Blaming and Labelling May Damage Health, Science and Policy Making. (pdf)
• Impact of Socioeconomic Status on Patient Characteristics and Postoperative Outcomes in Colorectal Cancer Surgery.
• fMRI Research: Do We Need Statistically Better Studies, Larger Studies, or No More Studies?
• Universal Transcriptomic Hallmarks of Mammalian Ageing and Mortality.
• RCT: Cooling Vest May Reduce Body Fat in Obesity.
• RCT: Effectiveness of a Mobile Health Exercise Program for Adults with Mobility Disabilities.

Announcements

• The 2026 American Society of Animal Science (ASAS) Annual Meeting as Part of the Companion Animal Program, Including the Session on “Rigor and Reproducibility in Nutrition Research.”

Featured

• Podcast: Your Doctor Is Watching the Wrong Number. LDL, ApoB & Heart Risk Explained. - Dr. Kevin Maki.
• Standardising Rodent & Other Animal Diets: A Call for Global Action.
• From Chow to Conclusions: Why Standardising Laboratory Animal Diets Is Essential for Rigor, Reproducibility, and Translational Relevance in Nutrition Research.
• Protein Decoys, Alcohol, and Energy Intake: Testing a Mechanistic-Ecological Model.
• An Appetite for Protein.

Headline vs Study

• Headline: Molecular Switch in Mice Links Energy Burning and Bone Health.
• Press Release: Discovery of Fat-Burning ‘Switch’ Could Lead to Advances in Bone Disease Treatments: In the Longer Run, Obesity Research Also Stands to Benefit from This Breakthrough.
• Study: Discovery of Glycerol Is an Allosteric Activator of Tissue-Nonspecific Alkaline Phosphatase. No Human Bone Treatments or Obesity Breakthroughs Reported.

Contrary or Null Findings

• Meta-Analysis: "Creatine supplementation does not significantly reduce inflammatory biomarkers in humans based on current evidence."
• "These findings are ... contrary to general expectations that higher resource availability should favor larger and more female-biased offspring" in bees.
• "Contrary to expectations, neither self-love nor body image significantly predicted self-acceptance directly. Furthermore, body image did not mediate the relationships between self-love or self-compassion and self-acceptance."
• "Contrary to previous findings, individuals in this sample appeared to be more motivated by alcohol misuse than disordered eating to engage in drunkorexia behavior."
• "Contrary to our expectations, social desirability did not moderate the effect of messages, suggesting that the findings are not attributable to self-presentation strategies" in “The effect of persuasive messaging on attitude and intention to reduce meat consumption - a mediation analysis.”
• "Our meta-analysis of randomised controlled trials comparing home-based interventions with control conditions suggests that home-based physical exercise is feasible and improves aerobic capacity, but does not confer significant benefits for functional capacity, muscle strength or quality of life in children and adolescents with chronic diseases."
• RCT: "In conclusion, this study showed that priming exercise did not improve performance when water polo players were analyzed as a whole group."
• RCT: "These findings do not support a neuroprotective effect of progressive aerobic exercise..." in Parkinson's Disease.
• RCT: "In older patients with overweight and persistent AF [atrial fibrillation], a low-calorie diet and behavioral support program was associated with significant weight loss at 8 months with no safety concerns but did not affect AF symptoms, AF burden, cardiac remodeling, or the need for further rhythm control interventions."

Basic

• Adipocyte-Specific NIK Depletion Enhances Energy Metabolism and Glucose Tolerance in Mice.
• C2orf74 Orchestrates Germ-Leydig Crosstalk to Inhibit White Adipose Tissue Browning in Male Mice.
• Gdf15 Expression in Thermogenic Adipocytes Regulates Diet-Induced Weight Gain in a Sex-Dependent Manner.

Scientific Rigor & Scholarly Dialogue

• Retraction Watch: Widely Criticized Keto Diet Study Retracted.
• Reassessment of Antibody-Based Detection of the Murine T Cell GLP-1 Receptor.
• A Call for Methodological Rigour: Suspending Systematic Reviews and Meta-Analyses of Observational Studies on Ultra-Processed Foods.
• Best (but Oft Forgotten) Practices: Applying the Target Trial Framework in Nutrition Research.
• Letter: Comment on Liu et al. Low-Carbohydrate Diets of Varying Macronutrient Quality and Risk of Type 2 Diabetes in Three U.S. Prospective Cohort Studies.
• Response to: Comment on Liu et al. Low-Carbohydrate Diets of Varying Macronutrient Quality and Risk of Type 2 Diabetes in Three U.S. Prospective Cohort Studies.

Clinical

• GLP-1 Agonists in Orthopedic Surgery: A Narrative Review of Bone Health and Surgical Implications.
• Factors That Influence the Implementation of Obesity Support in Dental Settings: An Observational Study in Texas.
• Meta-Analysis: Effectiveness of Pre-Pregnancy Weight Loss Interventions on the Risk of Gestational Diabetes Mellitus in Women with Overweight or Obesity.
• Systematic Review: Virtual Reality Interventions in Obesity and Eating Disorders.
• End-Of-Life Care for Hospitalized Patients with Severe Obesity.

Children and Adolescents

• Evaluation of a Behavioral Intervention to Support Adolescents Undergoing Bariatric Surgery Using the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) Framework.
• Systematic Review: Effects of Behavioural Interventions for Preventing Obesity in Young Children from Ethnic Minority Backgrounds.
• Prevalence of Overweight and Obesity Among Children in Greenland: A Growing Concern.
• Association of Birth Weight with General Obesity, Central Obesity, and MASLD in a Nationally Representative Sample of US Adolescents.
• Childhood BMI Trajectories and Risk of Overweight and Obesity in Young Adulthood.
• Early Life Socio Dietary Clusters and Later Overweight and Obesity Up to Age 15 in Australian Children: Evidence from the Longitudinal Study of Australian Children.

Surgery

• Impact of BMI on Two-Year Outcomes Following Meniscal Repairs and Meniscectomies in Pediatric and Adolescent Patients.
• Metabolic - Bariatric Surgery in Elderly Patients - Safety and Effectiveness in a Single-Center Cohort.
• Initiation of GLP-1 Receptor Agonists Treatment After Bariatric Metabolic Surgery and Major Adverse Cardiac Events.

Drugs

• RCT: Tirzepatide for Maintenance of Bodyweight Reduction in People with Obesity.
• RCT: Semaglutide Versus Placebo in Individuals with Poor Weight Loss After Bariatric Surgery.
• Weight Loss by Sodium-Glucose Co-Transporter 2 Inhibitor Canagliflozin Is Followed by Rebound in db/db Mice but Maintained in Fat-Fed Mice Via Circadian Rises in Body Temperature and Locomotor Activity.

Food & Diet

• RCT (Preprint): Ketogenic Diet or Exogenous Ketone Supplementation Restore Menstrual Activity in Women with PMOS: Preliminary Findings.
• The Emerging Role of Branched-Chain Amino Acid Metabolism in Obesity.
• Type I Corn Resistant Starch Attenuates Obesity in High-Fat Diet-Induced Mice by Modulating the Gut Microbiota, Appetite and Lipid Metabolism Genes.

Caloric and Dietary Restriction

• Methionine Restriction Extends Yeast Lifespan By Activating Non-Nitrogen-Starvation-Induced Autophagy Through Limiting Methylation of Protein Phosphatase 2A.
• Metabolic and Urinary Profiles in Normal-Weight, Overweight and Obese Dogs: Clinical Response to an Individualised Weight Loss Programme.
• Meta-Analysis: Effects of Calorie Restriction with and without Strength, Endurance or Mixed Training on Fat-Free and Skeletal Muscle Mass in Individuals with Overweight or Obesity.

Exercise & Physical Activity

• Meta-Analysis: Effects of Prenatal Exercise Interventions on Physical Activity, Sedentary Behaviour, Maternal Health, and Pregnancy Outcomes.
• The Mediating Effect of 24-H Movement Behaviors in the Association between Obesity-Related Comorbidities and Depression: Evidence from a Large-Scale Cohort Study.

Economics & Sociology

• Body Size, Cardiometabolic Risk, and Educational Disparities in Mortality Among U.S. Adults, 1988-2019.
• Association of Socioeconomic Status and Lifestyle Factors with Incident Diabetes Among Individuals with Prediabetes.
• Physical Stature as Human Capital: Consequences of Globalisation and Rising Injuries.

Epidemiology

• Inflammation Does Not Mediate Relationships between BMI/BMI-For-Age Z-Score and Retinol or Retinol-Binding Protein in Adult Women or Young Children Without Underweight, Wasting, or Malaria.
• Meta-Analysis: BMI and Activities of Daily Living Impairment.
• Prolactin in High-Metabolic Risk Pregnancies: Associations with Maternal Obesity and Metabolic Health.
• Antibiotic Use in the First 2 Years of Life Is Related to Longitudinal BMI Trajectories from 0 to 18 Years.
• Association between Obesity and Frailty: A Two-Sample Mendelian Randomization.
• Exome-Wide Association Study of Blood Lipids in 1,158,017 Individuals from Diverse Populations.
• Association between BMI and Mortality in Intensive Care Unit Patients with Sepsis.
• Optimal Dietary Patterns for Lower Weight Gain and Risk of Obesity Surrounding Menopause.
• Prevalence of Excess Adiposity Among US and Canadian Adults with and Without BMI-Defined Obesity.
• Association of BMI with Lower Extremity Long Bone Fracture Location.
• Review: Obesity and Biological Aging Across the Life Course.

Psychology & Neuroscience

• Associations between Food Addiction Symptoms, Food Intake and BMI-For-Age in Children from a Low-Income Region.
• Semaglutide Drives Weight Loss Through cAMP-Dependent Mechanisms in GLP1R-Expressing Hindbrain Neurons.
• Neurobiological Mechanisms of Second-Generation Antipsychotic-Induced Obesity: Interactions between Ghrelin Signaling and Neurotransmitter Systems.
• Meta-Analysis: Influence of Reward-Related Genetic Variants on BMI and Predisposition to Obesity.
• Central Nervous System Adaptation Mechanism of Obesity Induced by High-Fat High-Sucrose Diet: Differences in Brain Function between Obese and Obese Resistant Rats Based on fMRI.

Differential Population Circumstances, Exposures, Outcomes, and Effects

• Characterizing Disparities in GLP-1 Receptor Agonist Use Among US Adults with and without Diabetes.
• Health Inequities in Older Adults with Type 1 Diabetes: A Nationwide Registry Analysis of Sociodemographic and Clinical Profiles for Glycaemic Control and Complications.
• Associations of Social Determinants and Lifestyle Factors with Incidence and Dynamic Progression of Type 2 Diabetes in the Chinese Population.
• Built Environment-Modulated Epigenetics: The Epigenetic Consequences of Architecturally Mediated Allostatic Overload in the Built Environment.
• Distribution of Adult Certified Bariatric Surgery Centers in the United States: Are We Meeting the Needs of the People?
• Associations of Racialized Economic Segregation with the Prevalence of Unhealthy Behaviors and Poor Mental Health in the United States.

Stigma

• Weight Stigma Is Associated with Reduced Dietary Diversity in Women and Older Adults with Diabetes.
• Beyond Body Size: Gender Specific Associations between Self-Perceived Body Shape and Experienced and Internalized Weight Stigma.

Policy Related

• Systematic Review: The Impact of Front-Of-Pack Labeling on Social Inequality in Sugar Consumption and Purchase.
• Using Systems Archetypes to Understand System Behaviour and Identify Leverage Points for Change in Local Obesity Prevention in the Netherlands.
• U.S. Consumer Preferences for FDA Healthy Vs. Generic Healthy Food Labels: The Influence of Trust.
• RCT: The Impact of Restaurant Menu Eco Labels on Consumer Meal Selections.

Intergenerational Effects

• Early Maternal Obesity Shapes Offspring Development Through Immune Mechanisms.
• Maternal Obesity and the Embryonic Rewiring of Feeding Circuits: Beyond the Hypothalamus.
• Association between Pre-Pregnancy BMI and Neonatal Outcomes in Women Undergoing Assisted Reproductive Technology.

Ecology, Evolution, & Energetics

• Exploration of the Mechanism of Lipid Droplets Regulating Animal Adipose Tissue Thermogenesis.
• Jump Now, Pay Later: Saltatory Behavior Trades Off with Body Mass and Facilitates Shelter Repair in a Seed-Dwelling Insect.

Methods

• The (ab)use of Food Frequency Questionnaire Data in Substitution Modelling in Nutritional Epidemiology.
• Cross-Cultural Adaptation and Psychometric Validation of the Mindful Eating Scale in Chinese Individuals with Overweight or Obesity.
• Development and Validation of an Explainable Machine Learning-Based Risk Prediction Model for Obesity in Chinese Children and Adolescents.

Commentary

• How Do Fatty15 Gummies Help with Healthy Aging?
• Is Weight Cycling Clinically Harmful?
• Prof Emeritus Arne Astrup, Dairy Foods, Saturated Fats, and the Matrix.
• Scientists Discover How a Father’s Obesity Affects His Children’s Metabolism.
• Retatrutide Results Suggest a Change in the Order of Things.
• The Obesity Epidemic at a Crossroads Progress and Pitfalls.
• Exploring Nutritional Myths and Fake News: Impact and Counteractions.
• Clinical Trial Design Considerations to Improve Equitable Anti-Obesity Medication Access for Youth.
• The Weird Politics of Access to Obesity Care.
• Ultra-Processed Foods: Challenging Corporate Power and Promoting Local Food Systems to Reclaim Health.

General

• Reciprocal Cross-Feeding between Bacteria Can Limit the Emergence of Metabolic Dependencies.
• A Compendium of Reporting Guidelines for Traditional, Complementary, and Integrative Medicine from the Enhancing the QUAlity and Transparency of Health Research (EQUATOR) Network.
• National Academies Unveil a Roadmap for U.S. Statistical Science Through 2035.
• In Math, Rigor Is Vital. But are Digitized Proofs Taking It Too Far?
• Blueberries, Exercise, Memory, and Memories: Combining Open-Minded, Promising Inquiry with Rigorous, Trustworthy Scientific Research.
• Bottlenose Dolphin Reliance on Trawlers in Prey-Depleted Adriatic Sea Regions.
• Peroxisomes Orchestrate Metabolic Flexibility and Longevity Via an Interorganelle Cascade.
• Future of Continuous Ketone Monitoring and Its Utility for Safe Use of Sodium-Glucose Cotransporter-2 Inhibitors in Type 1 Diabetes.
• The Effect of Chronic Exogenous Ketone Use on Aortic Responses in Male and Female HFpEF Rats.

Video & Audio

• Podcast: Obicetrapib: The CETP Inhibitor with Cardiovascular Benefits and Potential Alzheimer's Prevention.
• Webinar: Understanding Metabolic Flexibility: Methods, Mechanisms, and Links to Cardiometabolic Disease.
• Podcast: How Do Clinical Trials Work, and Who Can Participate?

Announcements

• New Podcast Series from Stu Phillips.