Obesity and Energetics Offerings

Featured

• RCT: Effectiveness of Early Time-Restricted Eating for Weight Loss, Fat Loss, and Cardiometabolic Health in Adults with Obesity.
• Energy as the Cornerstone of Environmentally Driven Sex Allocation.
• The Associations between Relative and Absolute BMI with Mortality Rate Based on Predictions from Stigma Theory.
• Evaluating the Process to Develop the Dietary Guidelines for Americans, 2020-2025 a Midcourse Report (2022).

Headline vs Study

• Headline: Too Hot to Play! Childhood Obesity and Inactivity Increasing Because of Climate Change.
• Narrative Review: Climate change and childhood obesity, thermal stress, and physical fitness. Causal relations discussed but not established.

Contrary or Null Findings

• Calorie Restriction Has No Effect on Bone Marrow Tumour Burden in a Vk*MYC Transplant Model of Multiple Myeloma.
• RCT: "Treatment of neonatal hypoglycaemia (<2.6 mol/L) with dextrose gel does not alter neurosensory impairment at 4.5 years."
• Systematic Review: “The evidence for the efficacy of behavioral weight loss interventions for improving diet quality among adults with overweight and obesity is limited…”.
• RCT: “No significant alleviating effects of SM DNA [salmon milt DNA] were observed on the primary (hepatic functions and liver-to-spleen ratio), and secondary (NAFLD fibrosis score, serum protein levels, blood glucose, blood lipids, inflammatory markers, adipokines, cytokines, fatigue scoring, and skin conditions) endpoints.”
• RCT: “Unexpectedly, more products (+7.3 products)—albeit mostly healthy ones—and thus more calories (+1732 kcal) were purchased in the label conditions than in the control condition.”
• RCT: "…no FOPLs [Front-of-Package Labels] led to a reduction in intentions to purchase the packaged foods on Unhealthy Packaged Foods in India….”
• “Although romosozumab and active vitamin D3 combination therapy increased trabecular bone volume, there was no evidence on its ability to accelerate fracture healing” in rats.
• RCT: "There were no positive effects of daily intraindividual variations in the three examined factors on habit strength at the next day. There was an unexpected negative effect of daily behavioral performance on habit strength at the next day. We found little to no evidence for our expected and pre-registered interaction effects."

Basic

• Inulin Reduces Visceral Adipose Tissue Mass and Improves Glucose Tolerance Through Altering Gut Metabolites.
• Changes in Plasma Ghrelin Levels Following Surgical and Non-Surgical Weight-Loss in Female Rats Predict Alcohol Use.
• Mitochondrial Proteostasis Stress in Muscle Drives a Long-Range Protective Response to Alleviate Dietary Obesity Independently of ATF4.

Scientific Rigor & Scholarly Dialogue

• An Updated Framework for Industry Funding of Food and Nutrition Research: Managing Financial Conflicts and Scientific Integrity.
• Use of Pre-Post Treatment Values in Place of between Group Comparisons Invalidates Meta-Analysis Findings. Commentary: Can Millet Consumption Help Manage Hyperlipidemia and Obesity?: A Systematic Review and Meta-Analysis.
• Article: Deuterium-Depleted Water as Adjuvant Therapeutic Agent for Treatment of Diet-Induced Obesity in Rats.
• Letter: Re-Analysis and Additional Information Needed to Inform Conclusions. Comment on Halenova et al. Deuterium-Depleted Water as Adjuvant Therapeutic Agent for Treatment of Diet-Induced Obesity in Rats.

Clinical

• Parents’ Experiences Following Conversations About Their Young Child’s Weight in the Primary Health Care Setting: A Study Within the STOP Project.
• Raman Studies of the Adipose Tissue: Current State-Of-Art and Future Perspectives in Diagnostics.
• Elevated Heart Rate as Sympathetic Biomarker in Human Obesity.
• European Guideline on Obesity Care in Patients with Gastrointestinal and Liver Diseases - Joint ESPEN/UEG Guideline.
• Obesity Impairs Skeletal Muscle Repair Through NID-1 Mediated Extracellular Matrix Remodeling by Mesenchymal Progenitors.
• Effect of Aronia melanocarpa Fruit Juice on Glucose Tolerance, Lipid Metabolism, and Obesity in a Rat Model of Metabolic Syndrome.

Children and Adolescents

• Effects of Double Burden Malnutrition on Energetic Metabolism and Glycemic Homeostasis: A Narrative Review.
• At Their Own Pace: Optimal Walking Speed in Children and Adolescents.
• Does Childhood Obesity Trigger Neuroinflammation?

Surgery

• Altered Glucose Metabolism and Glucose Transporters in Systemic Organs After Bariatric Surgery.
• Obesity-Associated Sleep Hypoventilation and Increased Adverse Post-Operative Bariatric Surgery Outcomes in a Large Clinical Retrospective Cohort.
• Biochemical Markers and Obstructive Sleep Apnea Risk in Individuals After Long-Term Bariatric Surgery.
• Review: Endoscopic Management of Weight Recurrence Following Bariatric Surgery.

Drugs

• Narrative Review: Anti-Obesity Medications for Patients with Obesity and Osteoarthritis.
• Drivers of Medicalization in the Canadian Adult Obesity Clinical Practice Guidelines.
• A Co-Crystal Berberine-Ibuprofen Improves Obesity by Inhibiting the Protein Kinases TBK1 and IKKɛ.
• A New Use for Old Drugs: Identifying Compounds with an Anti-Obesity Effect Using a High Through-Put Semi-Automated Caenorhabditis elegans Screening Platform.
• Cinnamic Acid Attenuates Peripheral and Hypothalamic Inflammation in High-Fat Diet-Induced Obese Mice.
• Chemical Profiles and Antiobesity Effect of a Mixture of Astragalus Membranaceus and Lithospermum erythrorhizon Extract in High Fat Diet Fed Mice.

Food & Diet

• Review: The Potential of Honey as a Prebiotic Food to Re-Engineer the Gut Microbiome Toward a Healthy State.
• Flavonoids from Lycium barbarum Leaves Attenuate Obesity Through Modulating Glycolipid Levels, Oxidative Stress, and Gut Bacterial Composition in High-Fat Diet-Fed Mice.
• Polyphenol-Rich Oolong Tea Alleviates Obesity and Modulates Gut Microbiota in High-Fat Diet-Fed Mice.
• A Comparative Study on Roles of Natural Killer T Cells in Two Diet-Induced Non-Alcoholic Steatohepatitis-Related Fibrosis in Mice.

Caloric and Dietary Restriction

• RCT: Dietary Recommendations for Fasting Days in an Alternate-Day Intermittent Fasting Pattern.
• RCT: Effectiveness of Early Time-Restricted Eating for Weight Loss, Fat Loss, and Cardiometabolic Health in Adults with Obesity.

Exercise & Physical Activity

• Dose–Response Association of Aerobic and Muscle-Strengthening Physical Activity with Mortality: A National Cohort Study of 416 420 US Adults.
• Physical Activity Paradox: Could Inflammation Be a Key Factor?
• Resistance to Obesity Prevents Obesity Development Without Increasing Spontaneous Physical Activity and Not Directly Related to Greater Metabolic and Oxidative Capacity.
• Estrogen Regulation of Daily Metabolic Rhythms in Female Mice.
• Relationships Among Changes in Physical Activity, Quality of Life, and Obesity-Status Following a Behavioral Intervention for Rural Appalachian Adults.

Economics & Sociology

• Adversity and Child BMI in Fragile Families over 15 Years: Do Type and Timing Matter?
• The Influence of Routine and Leisure Family Activities on the Ability of Young Asian Americans to Maintain a Healthy Lifestyle: Findings from a Nationwide Survey.

Epidemiology

• Sex Differences in the Association between the Change in Triglyceride‑glucose Index and Cognitive Decline: A Population-Based Cohort Study.
• Epigenetic Epidemiology of Obesity and Type 2 Diabetes.

Psychology & Neuroscience

• The Relationship of Chronotypes with Food Addiction, Impulsivity, and Attention Deficit Hyperactivity Disorder Symptoms in a Sample of Undergraduate University Students.
• Preprint: Inhibitory Control Towards Angry Stimuli in Patients with Binge Eating Disorder – a Pilot Study.
• Testing Go/No-Go Training Effects on Implicit Evaluations of Unhealthy and Healthy Snack Foods.
• Impulsivity Is Longitudinally Associated with Healthy and Unhealthy Dietary Patterns in Individuals with Overweight or Obesity and Metabolic Syndrome Within the Framework of the PREDIMED-Plus Trial.

Equity and Disparities

• Healthy Schoolhouse 2.0 Strides Toward Equity in Obesity Prevention.
• Equality- Versus Equity-Based Approaches to Promoting Health and Fitness in Diverse Populations.
• Dissertation: Deletion of Period Genes Exacerbates Diet-Induced Obesity in Female, but Not Male, Mice.

Stigma

• Systematic Review: Couples Losing Kinship: A Systematic Review of Weight Stigma in Romantic Relationships.
• Does Weight Stigma Harm More Than Obesity?
• Meta-Analysis: Interventions for Reducing Weight Bias in Healthcare Providers.

Policy Related

• Translating Multisectoral Nutrition Policy Into Community Practice: Participation of Nutrition Officers in Tanzania Fosters Effective Collaborative Strategies to Improve Child Nutrition.
• Burden of Childhood Malnutrition: A Roadmap of Global and European Policies Promoting Healthy Nutrition for Infants and Young Children.
• Challenging Terrains: Socio-Spatial Analysis of Primary Health Care Access Disparities in West Virginia.
• Ethnic Differences in Fast-Food Advertising Exposure and BMI Among Asian American/Pacific Islander and White Young Adults.

Intergenerational Effects

• Optimal Gestational Weight Gain for Women with Obesity.
• Placental DNA Methylation in Pregnancies Complicated by Maternal Diabetes And/or Obesity: State of the Art and Research Gaps.
• Parent-Of-Origin Effects Propagate Through Networks to Shape Metabolic Traits.
• Insulin Increases Placental Triglyceride as a Potential Mechanism for Fetal Adiposity in Maternal Obesity.

Ecology, Evolution, & Energetics

• Energy Expenditure of Red-Footed Tortoises (Chelonoidis carbonaria) Fed Kibble Diets with High Levels of Fibre, Starch, or Fat.
• Nutrient Balance and Energy-Acquisition Effectiveness: Do Birds Adjust Their Fruit Diet to Achieve Intake Targets?
• Acute and Long-Term Effects of Psilocybin on Energy Balance and Feeding Behavior in Mice.

Methods

• The Relationship between BMI and Physical Activity Participation Rate Design Based on Fuzzy Breakpoint Regression Design.
• Abstract: Determining an Appropriate Statistical Model When Assessing the Association between Obesity and Mortality.

Commentary

• Opinion: Changing When and How Much We Eat May Extend Healthspan.
• First Case of Human PCSK9 Gene-Editing.
• Arrogant Beliefs About People Living with Obesity.
• Vitamin D(éjà Vu): New Study, Same Old Problems.
• Telemedicine or Telehealth for Obesity?
• Navigating Linear and Ponderal Growth in Undernourished Children.
• Statin Therapy Is Not Warranted for a Person with High LDL-Cholesterol on a Low-Carbohydrate Diet.

General

• Geometric Analysis Reveals How Birds Mastered Flight.
• Pregnancy-Induced Maternal Microchimerism Shapes Neurodevelopment and Behavior in Mice.
• Study: Monkeys Can Do Math.
• RCT: Frequently Interrupting Prolonged Sitting with Light Body-Weighted Resistance Activity Alters Psychobiological Responses to Acute Psychological Stress.
• Is There Resource Wastage in the Research for Spinal Diseases? An Observational Analysis of Discontinuation and Non-Publication in RCTs.
• RCT: Honey Had No Pharmacological Effect on Nocturnal Coughs and Sleep Quality at 1–5 years of Age.
• NASEM Report: Addressing Inaccurate and Misleading Information About Biological Threats Through Scientific Collaboration and Communication in Southeast Asia.
• Global Food Insecurity and Famine from Reduced Crop, Marine Fishery and Livestock Production Due to Climate Disruption from Nuclear War Soot Injection.

Video & Audio

• Podcast Episode 218: OMEGA-6 PUFAS, Inflammation & NAFLD – Dr. Martha Belury.
• Podcast: Exercise, VO2 Max, and Longevity | Mike Joyner, M.D.

Announcements

• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Scientific Meeting: Causes of Obesity: Theories, Conjectures and Evidence.
• Webinar: Barriers to Access Medical Care for Patients with Obesity.

Featured

• RCT: Morning Exercise Reduces Abdominal Fat and Blood Pressure in Women; Evening Exercise Increases Muscular Performance in Women and Lowers Blood Pressure in Men.
• Pharmacological Regulation of Melanocortin-3 And-4 Receptors by Melanocortin-2 Receptor Accessory Protein 1 or 2.
• "Contrary to our hypothesis, our results documented significant associations between adherence to the EAT-Lancet diet and incidence of cancer only in some subgroups, and no association with CVD."

Headline vs Study

• Headline: Strawberries May Fend Off Alzheimer's.
• Study: Associations between estimated pelargonidin intake (a compound found in strawberries) from food frequency questionnaires and neuropathological markers of Alzheimer's. "The study was an observational study and does not prove a direct causal relationship."

Contrary or Null Findings

• Systematic Review: "results from 6/6 RCTs favoured control with respect to body weight and composition, although most of these effects were small. This was contrary to cohort study results suggesting small benefits of walnut consumption on body weight."
• "Aerobic scope (AS) showed the same pattern as SMR, differing across habitats, but contrary to expectations, was lower in pelagic perch."
• "there is no evidence for proposed effects [of gluten] on driving appetite by the brain, nor on energy expenditure and weight gain. "
• RCT: "Men receiving radical RT and ADT gained weight and had increases in waist circumference over time, which metformin did not significantly mitigate."
• RCT: Null Effects of Inulin Supplementation on Body Composition and Metabolic Outcomes in Children with Obesity.
• Systematic Review: Low- and No-Calorie Sweetened Beverages "were not associated with cardiometabolic harm in analyses that model the exposure as change or substitutions."
• RCT: "timing of starting a weight loss attempt [does not appear to affect] ...weight change and trajectory after 12 months in adults newly diagnosed with moderate-severe OSA and treated at home with overnight CPAP."
• Meta-Analysis: "Based on low certainty evidence, early feeding may have little to no effect on necrotizing enterocolitis, feed intolerance, and days to regain birth weight."

Basic

• Octopamine Mediates Sugar Relief from a Chronic-Stress-Induced Depression-Like State in Drosophila.
• Codon-Optimized FAM132b Gene Therapy Prevents Dietary Obesity by Blockading Adrenergic Response and Insulin Action.
• The AAV-PCSK9 Murine Model of Atherosclerosis and Metabolic Dysfunction.
• T-Bet+ B Cells Accumulate in Adipose Tissue and Exacerbate Metabolic Disorder During Obesity.
• The Ameliorating Effects of Metformin on Disarrangement Ongoing in Gastrocnemius Muscle of Sarcopenic and Obese Sarcopenic Mice.
• Hepatokine Fetuin B Expression Is Regulated by Leptin-STAT3 Signalling and Associated with Leptin in Obesity.

Scientific Rigor & Scholarly Dialogue

• Letter: Troubling Assumptions Behind GBD 2019 on the Health Risks of Red Meat.
• Video: Debate - Should We Eat More Processed Foods?

Clinical

• Weight Loss Outcomes Achieved by Adults Accessing an Online Programme Offered as Part of Public Health England’s ‘Better Health’ Campaign.
• Association of Changes in Histologic Severity of Nonalcoholic Steatohepatitis and Changes in Patient-Reported Quality of Life.
• The Promise of New Anti-Obesity Therapies Arising from Knowledge of Genetic Obesity Traits.

Children and Adolescents

• The Association between Weight Loss and Long Term Development in Quality-Of-Life Among Children Living with Obesity: A Pragmatic Descriptive Intervention Study.
• Does Increasing Parental Knowledge of Healthy Behaviors Lead to Lifestyle Changes for Children with Overweight or Obesity? A Prospective Study. (pdf)
• Identifying Modifiable Obesogenic Behaviors Among Latino Adolescents in Primary Pediatric Care.
• Thesis: Digitally-Delivered Healthcare for Children and Adolescents with Obesity.
• Systematic Review: Healthy and Sustainable Dietary Patterns in Children and Adolescents.
• A Longitudinal Effectiveness Study of a Child Obesity Electronic Health Record Tool.

Surgery

• Perception of Bariatric Surgery and Endoscopic Bariatric Therapies Among Primary Care Physicians.
• Behavioral Interventions to Attenuate Driven Overeating and Weight Regain After Bariatric Surgery.
• Innovative Bariatric Procedures and Ethics in Bariatric Surgery: The IFSO Position Statement.
• RCT: Endoscopic Sleeve Gastroplasty for Treatment of Class 1 and 2 Obesity (MERIT).

Drugs

• Discovery of MK-1462: GLP-1 and Glucagon Receptor Dual Agonist for the Treatment of Obesity and Diabetes.
• In Silico and in Vitro Analysis of PPAR – α / γ Dual Agonists: Comparative Evaluation of Potential Phytochemicals with Anti-Obesity Drug Orlistat.
• Effect of HIV and Antiretroviral Therapy Use on Body Weight Changes in a Cohort of U.S. Veterans Living with and Without HIV.

Food & Diet

• RCT: Effect of a Peanut-Enriched Weight Loss Diet Compared to a Low-Fat Weight Loss Diet on Body Weight, Blood Pressure, and Glycemic Control.
• Cinnamon Extract Improves Abnormalities in Glucose Tolerance by Decreasing Acyl-CoA Synthetase Long-Chain Family 1 Expression in Adipocytes.
• Dose-Response Relationship between Dietary Inflammatory Index and Diabetic Kidney Disease in US Adults.

Caloric and Dietary Restriction

• RCT: Effectiveness of Early Time-Restricted Eating for Weight Loss, Fat Loss and Cardiometabolic Health in Adults with Obesity.
• Life-Long Dietary Restrictions Have Negligible or Damaging Effects on Late-Life Cognitive Performance: A Key Role for Genetics in Outcomes.
• Unexpected Role for IGF-1 in Starvation: Maintenance of Blood Glucose.
• RCT: Effect of 5:2 Fasting Diet on Liver Fat Content in Patients with Type 2 Diabetes with Nonalcoholic Fatty Liver Disease.

Exercise & Physical Activity

• Systematic Review: Golf and Physical Health.
• Mathematical Modeling Reveals Differential Dynamics of Insulin Action Models on Glycerol and Glucose in Adolescent Girls with Obesity.
• A Latent Transition Analysis of Physical Activity and Screen-Based Sedentary Behavior from Adolescence to Young Adulthood.

Economics & Sociology

• Non-Farm Employment Promotes Nutritious Diet Without Increasing Carbon Footprint: Evidence from Rural China.
• RCT: The Impact of Increasing the Availability of Lower Energy Foods for Home Delivery and Socioeconomic Position.

Epidemiology

• The Timing of Adiposity and Changes in the Life Course on the Risk of Cancer.
• Obesity and Lifestyle Habits Among Kidney Transplant Recipients.
• The Weight of Childhood Adversity: Evidence That Childhood Adversity Moderates the Impact of Genetic Risk on Waist Circumference in Adulthood.
• Smoothened Percentiles for Height, Weight and BMI of Urban School Going Adolescents Aged 11-17 Years in National Capital Territory Region of Delhi, India.
• Exposure to Outdoor and Indoor Air Pollution and Risk of Overweight and Obesity Across Different Life Periods: A Review.
• Systematic Review: Body Composition and Prostate Cancer Risk.
• Obesity in Young Sudden Cardiac Death: Rates, Clinical Features, and Insights Into People with BMI >50kg/m2.

Psychology & Neuroscience

• Perceived Intrinsic, Social, and Environmental Barriers for Weight Management in Older Hispanic/Latino Adults with Obesity.
• Barriers and Facilitators of Participation in Weight Loss Intervention for Patients with Suboptimal Weight Loss After Bariatric Surgery.
• RCT: A Feasibility Study of Food-Related Computerised Attention Training Versus Mindfulness Training for Adults with Overweight or Obesity.
• Impulsivity Is Longitudinally Associated with Healthy and Unhealthy Dietary Patterns in Individuals with Overweight or Obesity and Metabolic Syndrome Within the Framework of the PREDIMED-Plus Trial.

Equity and Disparities

• Impact of Trends and Gender Disparity in Obesity on Future Type 2 Diabetes in Turkey: A Mathematical Modelling Analysis.
• Regional Disparities in Dual Burden of Malnutrition Among Rural Men in India: Evidence from National Family Health Survey.
• Translating the Recommended Multicomponent Intervention for Childhood Overweight and Obesity Into Practice: Implementation Challenges.
• Mitigating Breast Cancer Disparities by Addressing the Obesity Epidemic.

Stigma

• Weight Stigma of Nutrition and Dietetics Students Towards People with Obesity.
• Comparison of Perceived Weight Discrimination between Polish and German Patients Underwent Bariatric Surgery or Endoscopic Method Versus Conservative Treatment for Morbid Obesity: An International Multicenter Study.

Policy Related

• From Healthy Food Environments to Healthy Wellbeing Environments: Policy Insights from a Focused Ethnography with Low-Income Parents’ in England.
• Reshaping Food Policy and Governance to Incentivize and Empower Disadvantaged Groups for Improving Nutrition.
• Strengthening US Food Policies and Programs to Promote Equity in Nutrition Security: A Policy Statement from the American Heart Association.

Intergenerational Effects

• Maternal and Neonatal Outcome of Women Before Vs. After Bariatric Surgery: A Single Tertiary Center Experience.
• Association of Prepregnancy Physical Activity with Obesity in Offspring: The Japan Environment and Children's Study.
• Systematic Review: General Parenting Intervention Impacts on Child Weight as a Secondary Outcome.
• Prospective Relations of Maternal Reward-Related Eating, Pregnancy Ultra-Processed Food Intake and Weight Indicators, and Feeding Mode with Infant Appetitive Traits.

Ecology, Evolution, & Energetics

• The Comparative Energetics of the Carnivorans and Pangolins.
• Overwintering in North American Domesticated Honeybees (Apis mellifera) Causes Mitochondrial Reprogramming While Enhancing Cellular Immunity.

Methods

• Biological Age for Chronic Kidney Disease Patients Using Index Model.
• Body Weight and Obstructive Sleep Apnea: A Mathematical Relationship between BMI and Apnea-Hypopnea Index in Veterans.
• Accuracy of Body Composition Measurement Techniques Across the Age Span.
• Towards Systems Models for Obesity Prevention: A Big Role for Big Data.
• Novel Approaches to Evaluate Dietary Quality: Combining Methods to Enhance Measurement for Dietary Surveillance and Interventions.

Mathematical and Quantitative

• Dietary Alterations in Impaired Mitochondrial Dynamics Due to Neurodegeneration.
• Can Math Help Us Understand the Gut System of People with Obesity?

Commentary

• When Modern Science Meets Ancient Traditions.
• Avoiding Injury Part II: Grip Strength.
• Health Benefits and Risks of Chocolate.
• Childhood Obesity, Part 2: We Could Fix It… Any Time We Wanted.
• Fresh, Canned, or Frozen: Which Is Better?
• Does Eating High-Fat Dairy Cause Heart Disease or Obesity? Has the Science Changed in the Last Decade?
• Semaglutide SELECT Study: No News Is News.
• When Scientific Paradigms Collide - What If Overeating Doesn’t Make You Fat?

General

• Research Culture: Highlighting the Positive Aspects of Being a PhD Student.
• Dogs and the Good Life: A Cross-Sectional Study of the Association between the Dog-Owner Relationship and Owner Mental Wellbeing.
• Clinical Features Distinguishing Diabetic Retinopathy Severity Using Artificial Intelligence.
• NIH Launches Experimental Science Rigor Initiative.
• Constructive and Obsessive Criticism in Science.
• Rigor and Transparency Index: Large-Scale Analysis of Scientific Reporting Quality.
• Comparative Genome Anatomy Reveals Evolutionary Insights Into a Unique Amphitriploid Fish.
• Retractions are Increasing, but Not Enough.

Announcements

• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency And/ or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• Civic Champs from Bloomington, IN Was Named the Winner of 2022 HungerTech Challenge.
• Webinar: Spreading Effective Interventions to Support Healthy Child Growth: CDC’s Data Modernization and Implementation Science Efforts August 18, 2022, 2:00 P.m. ET.
• IU's Dr. Nasser Paydar Confirmed as Assistant Secretary for Postsecondary Education.

Featured

• No Evidence for Nudging After Adjusting for Publication Bias.
• Human Total, Basal and Activity Energy Expenditures are Independent of Ambient Environmental Temperature.
• The Evolution of Dog Diet and Foraging: Insights from Archaeological Canids in Siberia.
• Hepatic TORC2 Signaling Facilitates Acute Glucagon-Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice.

Headline vs Study

• Headline: Transport for London Junk Food Ad Restrictions ‘Have Led to Fewer Obesity Cases’.
• Press Release: Junk Food Advertising Restrictions Prevent Almost 100,000 Obesity Cases.
• Study: Micro Simulation Health Economic Modeling Study of London Obesity Rates.
• Critique: Obesity in London? 100,000 Cases Prevented!

Contrary or Null Findings

• RCT: "No significant intervention group differences were observed...[in]...multiple-component mindfulness intervention for Chinese adolescents living with overweight."
• RCT: Three Weeks of Time-Restricted Eating Improves Glucose Homeostasis in Adults with Type 2 Diabetes but Does Not Improve Insulin Sensitivity.
• RCT: Dihydrocapsiate Does Not Increase Energy Expenditure nor Fat Oxidation During Aerobic Exercise in Men with Overweight/obesity. (PDF)
• RCT: No Significant Effects of Treatment Assignment in Cardiometabolic Effects of Early Vs. Delayed Time-Restricted Eating Plus Caloric Restriction in Adults with Overweight and Obesity.
• RCT: Vitamin D3 Supplementation Did Not Result in a Significantly Lower Risk of Fractures Than Placebo Among Generally Healthy Midlife and Older Adults Who Were Not Selected for Vitamin D Deficiency, Low Bone Mass, or Osteoporosis.
• "Contrary to studies in residential areas and schools, nutrition environments were not related to nutrition practices in ECEs."
• "No school-level factor was statistically associated with the sustainment of overall weekly PA or energisers scheduled."
• RCT: "Intuitive eating alone or in combination with nutritional guidelines did not alter the general domains of eating behaviors, weight, and BMI in individuals with obesity."

Basic

• Cooperative Action of Gut-Microbiota-Accessible Carbohydrates Improves Host Metabolic Function.
• Early Life Dietary Exposures Mediate Persistent Shifts in the Gut Microbiome and Visceral Fat Metabolism.
• Disruption of Adipocyte HIF-1α Improves Atherosclerosis Through the Inhibition of Ceramide Generation.

Scientific Rigor & Scholarly Dialogue

• Competing Paradigms of Obesity Pathogenesis: Energy Balance Versus Carbohydrate-Insulin Models.
• A Brief History and Future of the Traffic Light Diet.
• Support Europe’s Bold Vision for Responsible Research Assessment.
• Article: Perspective: Obesity—an Unexplained Epidemic.
• Letter: Could Increasing Inequalities in Energy Intake Partly Explain the Increasing Prevalence of Obesity Despite a Leveling Mean Intake?

Clinical

• RCT: Effects of Inulin Supplementation on Body Composition and Metabolic Outcomes in Children with Obesity.
• Obesity Indexes are Positively Correlated with Blood Pressure Variability in Patients with Essential Hypertension.
• Preventing Obesity in Midlife Women: A Recommendation from the Women's Preventive Services Initiative.
• Meta Analysis: Impact of Program Characteristics on Weight Loss in Adult Behavioral Weight Management Interventions.

Children and Adolescents

• “Fat but Fit” Paradox and Cardiometabolic Risk in Children: The Role of Physical Activity.
• Diagnosis Accuracy of Waist-To-Height Ratio to Predict Cardiometabolic Risk in Children with Obesity.
• Green and Blue Spaces and Lung Function in the Generation XXI Cohort: A Life Course Approach.
• Trends in Obesity Prevalence Among Children and Adolescents Aged 2 to 19 Years in the US from 2011 to 2020.

Surgery

• RCT: Weight Loss and β-Cell Responses Following Gastric Banding or Pharmacotherapy in Adults with Impaired Glucose Tolerance or Type 2 Diabetes.
• Review: The Impact of Bariatric and Metabolic Surgery on Cancer Development.
• Altered Glucose Metabolism and Glucose Transporters in Systemic Organs After Bariatric Surgery.
• Meta-Analysis: De Novo Inflammatory Bowel Disease Following Bariatric Surgery.

Drugs

• Meta-Analysis: Metformin and Thyroid Carcinoma Incidence and Prognosis.
• Preclinical Efficacy of INST3399, a Synthetic Novel PKCbeta Inhibitor, for the Treatment of Obesity and Fatty Liver Disease.
• Obesity Treatment - Overview of Pharmacological and Surgical Methods.

Food & Diet

• About EAT-Lancet 2.0.
• USPSTF Final Research Plan: Food Insecurity.
• Meta-Analysis: Efficacy of the Omega-3 Fatty Acids Supplementation on Inflammatory Biomarkers.
• Food Insecurity, Food Environments, and Disparities in Diet Quality and Obesity in a Nationally Representative Sample of Community-Dwelling Older Americans.
• Identification of Different Lipoprotein Response Types in People Following a Mediterranean Diet Pattern with and Without Whole Eggs.
• Review: A Conceptual Framework for Understanding the Environmental Impacts of Ultra-Processed Foods and Implications for Sustainable Food Systems.

Caloric and Dietary Restriction

• Temporal Dynamics of the Intestinal Microbiome Following Short-Term Dietary Restriction.
• Podcast: Matt Kaeberlein Discusses Healthspan, Longevity, and Rapamycin. 
• Podcast: Why Do We Get Old, and Can Aging Be Reversed?

Exercise & Physical Activity

• Sedentary Behavior and Cardiovascular Disease Risk: An Evolutionary Perspective.
• Career-Best Changes in Body Mass and Physical Fitness Test Performance Among Division 1 College Football Players Encompassing 28 Years at the Same Institution.
• Meta-Analysis: Effects of Physical Exercise on Bone Mineral Density in Older Postmenopausal Women.
• Phosphoproteomics of Three Exercise Modalities Identifies Canonical Signaling and C18ORF25 as an AMPK Substrate Regulating Skeletal Muscle Function.

Economics & Sociology

• Exploring the Relationship between Self-Employment and Women’s Cardiovascular Health.
• The Association between the Presence of Fast-Food Outlets and BMI: The Role of Neighbourhood Socio-Economic Status, Healthy Food Outlets, and Dietary Factors.
• Assessing the Affordability of Nutrient-Adequate Diets.

Epidemiology

• Gender Differences in the Relationship between Food Insecurity and BMI Among Adults in the USA.
• Preprint: Association of Machine Learning-Derived Measures of Body Fat Distribution in >40,000 Individuals with Cardiometabolic Diseases.
• Analysis of Somatic Mutations in 131 Human Brains Reveals Aging-Associated Hypermutability.
• Analysis of Epigenetic Age Acceleration and Healthy Longevity Among Older US Women.

Psychology & Neuroscience

• The Association between Childhood Trauma and Overweight and Obesity in Young Adults: The Mediating Role of Food Addiction.
• Evidence for a Neuromuscular Circuit Involving Hypothalamic Interleukin-6 in the Control of Skeletal Muscle Metabolism.

Equity and Disparities

• Disparities in Sleep Duration Among American Children: Effects of Race and Ethnicity, Income, Age, and Sex.
• A Healthy Plant-Based Diet Was Associated with Slower Cognitive Decline in African American Older Adults: A Biracial Community-Based Cohort.
• Preprint: Decades of Systemic Racial Disparities in Funding Rates at the National Science Foundation.

Stigma

• Anti-Fat Attitudes Among Spanish General Population: Psychometric Properties of the Anti-Fat Attitudes Scale.
• Weight-Based Teasing, Body Dissatisfaction, and Eating Restraint: Multilevel Investigation Among Primary Schoolchildren.
• Video: Weight Stigma in the Media - Panel Discussion.

Policy Related

• Supply Chain Crisis Leads to 60% Increase in Food Waste in Just Six Months.
• Benchmarking the Nutrition-Related Commitments and Practices of Major French Food Companies.
• An 18-Country Analysis of the Effectiveness of Five Front-Of-Pack Nutrition Labels.

Intergenerational Effects

• Intrauterine Malnutrition Disrupts Leptin and Ghrelin Milk Hormones, Programming Rats.
• Evaluation of Subclinical Atherosclerosis and Cardiac Functions in Children of Mothers with Gestational Diabetes and Maternal Obesity.

Ecology, Evolution, & Energetics

• Review: Hindbrain Circuits in the Control of Eating Behaviour and Energy Balance.
• Genome Size Drives Morphological Evolution in Organ-Specific Ways.

Methods

• A Strategy for Accurately and Sensitively Quantifying Free and Esterified Fatty Acids Using Liquid Chromatography Mass Spectrometry.
• How to Avoid Overestimating the Burden of Hypertension in Epidemiological Studies? A New Methodology to Account for Within-Person Variability of Blood Pressure.

Commentary

• Intermittent Fasting and the Ketogenic Diet: Why They are Harmful.
• Vitamin D: The Panacea That Isn’t.
• Childhood Obesity Worsens: Fiddlers, All, as Rome Burns?
• Energy Balance Versus Insulin and Carbs, Again.
• CRISPR-Based Genome Editing for Nutrient Enrichment in Crops: A Promising Approach Toward Global Food Security.
• How Humans Adapted to Digest Lactose — After Thousands of Years of Milk Drinking.
• Diverse Thinking About the Complexity of Obesity.
• Emergency Contraception Caution for Women with Obesity.
• What If the Focus on Calories and Energy Balance Is Simply Wrong?
• When Is Obesity Care Worth It?

General

• Video: What Role Does Google Play in Public Health?
• Invasive Fish: Sperm Hijacking as Success Strategy.
• How Do Fitness Trackers Monitor Your Sleep?
• Climate Change May Be Culprit in Antarctic Fish Disease Outbreak.
• Commentary On: The Fallacy of Science Is Science: The Impact of Conflict of Interest in Vaping Articles.
• Are You Clumsy—or Just Mean? Your Dog May Know the Difference.
• The Impact of Optical Impressions on Dog Feeding Practice.
• "Craft beer showed greater acceptance when consumed to the sound of classic rock."
• A.I. Predicts the Shape of Nearly Every Protein Known to Science.
• Distinguishing Bad Use of Science from Bad Science.

Announcements

• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency And/or Statistical and Data Analytic Research in the Obesity, Nutrition, or Aging Research Domains.
• "U.S. News & World Report has released its 2022-2023 ‘Best Hospitals’ rankings that include Indiana University Health Medical Center among the nation’s top adult hospitals for the 25th consecutive year."
• "Registration is now open for the causes of obesity meeting at the Royal Society (London Oct 17-19th 2022). Free to attend. Unlimited online places. In person attendance numbers are limited."

Featured

• An Analysis of the Recent U.S. Dietary Guidelines Process in Light of Its Federal Mandate and a National Academies Report.
• Age and Diet Shape the Genetic Architecture of Body Weight in Diversity Outbred Mice.
• Tirzepatide Once Weekly for the Treatment of Obesity.
• Review: Bioactive Compounds in Mothers Milk Affecting Offspring Outcomes.

Headline vs Study

• Headline: Common Migraine Prescription Could Treat Obesity: Study.
• Press Release: UTSW Researchers Show Effectiveness of Migraine Drug in Weight Loss.
• Study: Delineating a Serotonin 1B Receptor Circuit for Appetite Suppression ... In Mice.

Contrary or Null Findings

• RCT: "No statistically significant differences were observed between low and high avocado allotment groups in liver enzymes, GGT, hsCRP or NAFLD fibrosis score."
• RCT: "The [Small Change Approach] did not prevent weight gain compared with monitoring alone at 2 or 3 years in adults with overweight or obesity".
• "Together, contrary to our hypothesis, heat-killed probiotics did not improve neutrophil function and survival outcome in a murine severe burn injury model."
• "Contrary to affect regulation theory and laboratory data, but consistent with prior ecological momentary assessment data in children and adolescents, pre-meal NA was not linked to subsequent LOC-eating."
• Antibiotic Therapy Does Not Alter Mitochondrial Bioenergetics in Lymphocytes of Patients with Septic Shock – a Prospective Cohort Study.
• RCT: Blood Flow Restriction Therapy for Two Weeks Prior to Anterior Cruciate Ligament Reconstruction Did Not Impact Quadriceps Strength Compared to Standard Therapy.
• No Association between Infant Growth and Adherence to the Dietary Approaches to Stop Hypertension (DASH) Diet in Lactating Women.
• RCT: "...daily consumption of 24 ml concentrated BJ [beetroot juice] did not affect the levels of glycemic measures, blood pressure, and lipid profile."
• RCT: "Findings indicated that the intervention did not produce take-home effects on children's home availability of fruit (p = 0.52) and vegetables (p = 0.67) or parental modelling of fruit (p = 0.26) and vegetable consumption (p = 0.78)..."

Basic

• The Gene Knockout of Angiotensin II Type 1a Receptor Improves High-Fat Diet-Induced Obesity in Rat Via Promoting Adipose Lipolysis.
• Macrophage-Specific Connexin 43 Knockout Protects Mice from Obesity-Induced Inflammation and Metabolic Dysfunction.
• Adipose Tissue Myeloid-Lineage Neuroimmune Cells Express Genes Important for Neural Plasticity and Regulate Adipose Innervation.
• A Signature of Exaggerated Adipose Tissue Dysfunction in Type 2 Diabetes Is Linked to Low Plasma Adiponectin and Increased Transcriptional Activation of Proteasomal Degradation in Muscle.
• Multiomics Reveals Persistence of Obesity-associated Immune Cell Phenotypes in Adipose Tissue During Weight Loss and Weight Regain in Mice.
• Preprint: Plasma Level of ATPase Inhibitory Factor 1 (IF1) Is Associated with Type 2 Diabetes Risk in Humans: A Prospective Cohort Study.

Scientific Rigor & Scholarly Dialogue

• Preprint: Limitations of the Food Compass Nutrient Profiling System.
• Avoiding the Effects of Translocation on the Estimates of the Metabolic Rates Across an Elevational Gradient.

Clinical

• Untargeted Lipidomic Analysis of Plasma from Women with Obesity Submitted to Combined Physical Exercise.
• Do Lifestyle Factors and Quality of Life Differ in People with Metabolically Healthy and Unhealthy Obesity?

Children and Adolescents

• Making Every Bite Count: Best Practices for Introducing Foods During the Complementary Feeding Period.
• The 100 Top-Cited Articles on Childhood Obesity: A Bibliometric Analysis.

Surgery

• T and B Cell Composition and Cytokine Producing Capacity Before and After Bariatric Surgery.
• Changes in the Expression of Meteorin-Like (METRNL), Irisin (FNDC5), and Uncoupling Proteins (UCPs) After Bariatric Surgery.
• De Novo Glycine Synthesis Is Reduced in Adults with Morbid Obesity and Increases Following Bariatric Surgery.
• RCT: Weight Loss and β-Cell Responses Following Gastric Banding or Pharmacotherapy in Adults with Impaired Glucose Tolerance or Type 2 Diabetes.
• Desire to Lose Weight Was Associated with the Adoption of Weight Control Strategies but Not Healthier Lifestyle Behaviours Among Post-Bariatric Surgery Patients: NHANES 2013–2018.

Drugs

• Hypoglycemia Risk with SGLT2 Inhibitors or Glucagon-Like Peptide 1 Receptor Agonist Versus Sulfonylureas Among Medicare Insured Adults with CKD in the United States.
• Melanocortin-4 Receptor Complexity in Energy Homeostasis, Obesity and Drug Development Strategies.
• Dysosmobacter welbionis Is a Newly Isolated Human Commensal Bacterium Preventing Diet-Induced Obesity and Metabolic Disorders in Mice.
• Meta-Analysis: Effect of Glucagon-Like Peptide-1 Receptor Agonists on Body Weight in Adults with Obesity Without Diabetes Mellitus.
• RCT: Semaglutide Once a Week in Adults with Overweight or Obesity, with or Without Type 2 Diabetes in an East Asian Population (STEP 6).

Food & Diet

• Body Weight Index Indicates the Responses of the Fecal Microbiota, Metabolome and Proteome to Beef/Chicken-Based Diet Alterations in Chinese Volunteers.
• The Relationship between Dietary Phytochemical Index and Resting Metabolic Rate Mediated by Inflammatory Factors in Women with Overweight and Obesity: A Cross-Sectional Study.
• RCT: Apnoea Occurring in Females Who are Overweight After Menopause.

Caloric and Dietary Restriction

• RCT: Dietary Protein Restriction Improves Metabolic Dysfunction in Patients with Metabolic Syndrome.
• Modestly Increased Incidence of Ketosis in Caloric Restriction Does Not Significantly Alter the Effects of Caloric Restriction.

Exercise & Physical Activity

• School and Non-School Day Screen Time Profiles and Their Differences in Health and Educational Indicators in Adolescents.
• Genome-Wide Association Study of Liking for Several Types of Physical Activity in the UK Biobank and Two Replication Cohorts.

Economics & Sociology

• Changes in Neighborhood Environments and the Increasing Socioeconomic Gap in Child Obesity Risks: Evidence from Singapore.
• The Role of Health-Based Food Choice Motives in Explaining the Relationship between Lower Socioeconomic Position and Higher BMI in UK and US Adults.
• Estimating the Benefits of Obesity Prevention on Productivity: An Australian Perspective.
• Changes in the Local Food-At-Home Environment, Supplemental Nutrition Assistance Program Participation, and Dietary Quality.

Epidemiology

• BMI Moderates the Association between Adverse Childhood Experiences and COPD.
• Obesity Fact Sheet in Korea, 2021: Trends in Obesity Prevalence and Obesity-Related Comorbidity Incidence Stratified by Age from 2009 to 2019.

Psychology & Neuroscience

• More Complex Than You Might Think: Neural Representations of Food Reward Value in Obesity.
• “You are Always at War with Yourself” the Perceptions and Beliefs of People with Obesity Regarding Obesity as a Disease.
• Review: Acts of Appetite: Neural Circuits Governing the Appetitive, Consummatory, and Terminating Phases of Feeding.
• More Complex Than You Might Think: Neural Representations of Food Reward Value in Obesity.
• Objective Physical Activity Accumulation and Brain Volume in Older Adults: An MRI and Whole Brain Volume Study.

Equity and Disparities

• Inequalities in Overweight and Obesity Among Reproductive Age Group Women in India: Evidence from National Family Health Survey (2015–16).
• Income Disparities in Obesity Trends Among U.S. Adults: An Analysis of the 2011–2014 California Health Interview Survey.
• Income-Related Health Inequality in Urban China (1991–2015): The Role of Homeownership and Housing Conditions.

Stigma

• A Public Health Framework for Reducing Stigma: The Example of Weight Stigma.
• Preprint: Mediators of the Association between Childhood BMI and Educational Attainment: Analysis of a UK Prospective Cohort Study.

Policy Related

• The Relationship between Volume of Newspaper Coverage and Policy Action for Nutrition Issues in Australia: A Content Analysis.
• Integrating Nutrition and Food Safety in Food Systems Policy and Programming.
• Intergovernmental Policy Opportunities for Childhood Obesity Prevention in Australia.

Intergenerational Effects

• In-Utero Co-Exposure to Toxic Metals and Micronutrients on Childhood Risk of Overweight or Obesity: New Insight on Micronutrients Counteracting Toxic Metals.
• Associations between Family Functioning During Early to Mid-Childhood and Weight Status in Childhood and Adolescence.

Ecology, Evolution, & Energetics

• Parents Exposed to Warming Produce Offspring Lower in Weight and Condition.
• Genomic Insights Into the Secondary Aquatic Transition of Penguins.
• Diet and Ontogeny Drastically Alter the Larval Microbiome of the Invertebrate Model Galleria mellonella.
• Circulating and Skeletal Muscle MicroRNA Profiles are More Sensitive to Sustained Aerobic Exercise Than Energy Balance in Males.

Methods

• Systematic Review: The Use of Mobile-Based Ecological Momentary Assessment (mEMA) Methodology to Assess Dietary Intake, Food Consumption Behaviours and Context in Young People.
• Dietary Assessment -- Pattern Recognition Rather Than Recall.
• Comparison of Weight Loss Data Collected by Research Technicians Versus Electronic Medical Records: The PROPEL Trial.
• Next Generation Smartwatches to Estimate Whole Body Composition Using Bioimpedance Analysis: Accuracy and Precision in a Diverse Multiethnic Sample.

Mathematical and Quantitative

• Predictive Equations for Energy Expenditure in Adult Humans: From Resting to Free-Living Conditions.
• Obesity and Labour Market Outcomes in Italy: A Dynamic Panel Data Evidence with Correlated Random Effects.
• The Health, Cost and Equity Impacts of Restrictions on the Advertisement of High Fat, Salt and Sugar Products Across the Transport for London Network: A Health Economic Modelling Study.

Commentary

• Genetic Effects: Accounting for Diet and Age.
• Why Don’t Most Foods Cause Allergies?
• Improving Health Through Food Engineering.
• As Diabetes During Pregnancy Grows More Common, Experts Point to a Need for Preventive Care.
• What are the Health Benefits of Watermelon?
• Dietary Assessment: Do We Really Know What People are Eating?
• Is Air Conditioning Causing Obesity?
• Overly Restrictive Salt Intake May Worsen Outcomes for Common Form of Heart Failure.

General

• Remote Video Analysis of an Unusual Fish Life-History Combination: Nest-Building, Paternal Care, and Protogyny in a Seabream.
• Dietary Bacillus licheniformis Improves the Effect of Astragalus membranaceus Extract on Blood Glucose by Regulating Antioxidation Activity and Intestinal Microbiota in InR[E19]/TM2 Drosophila melanogaster.
• Contrary to Popular Belief, Woodpeckers Don’t Protect Their Brains When Headbanging Trees.
• Fact-Value Framework for Adjudicating Public Health Policy Debates.
• A Neuroscience Image Sleuth Finds Signs of Fabrication in Scores of Alzheimer’s Articles, Threatening a Reigning Theory of the Disease.
• Prolonged Administration of Melatonin Ameliorates Liver Phenotypes in Cholestatic Murine Model.
• What Can We Learn from Selfish Loci That Break Mendel’s Law?
• Food Waste Is a Complex Problem That Requires Creative Solutions.
• Food Expiration Dates Don’t Have Much Science Behind Them.

Announcements

• IU School of Public Health-Bloomington Invites Applications for a Post-Doctoral Fellow with Strong Data Analytic and Collaborative Skills to Join a Team of Researchers Focused on Rigor, Reproducibility, and Transparency and/or Statistical and Data Analytic Research in the Obesity, Nutrition or Aging Research Domains.
• Nine IU Faculty Members Named Fulbright US Scholar Award Winners for 2022-23 .
• Webinar: Spreading Effective Interventions to Support Healthy Child Growth: CDC’s Data Modernization and Implementation Science Efforts.